06/10/2008

C. O. Lemley, S. T. Butler, W. R. Butler, and M. E. Wilson. Short communication: insulin alters hepatic progesterone catabolic enzymes cytochrome P450 2C and 3A in dairy cows. J.Dairy Sci 91 (2):641-645, 2008.

Ferguson DE, Tsang PCW, Schreiber DT, Keator CS, Milvae RA, McCracken JA. 2007. In vivo changes in protein expression of the gelatinases, matrix metalloproteinases-2 and -9 (MMP-2 and MMP-9), and tissue inhibitor of metalloproteinases-1 (TIMP-1) in the ovine corpus luteum (CL) after multiple pulses of prostaglandin F2 alpha (PGF2±). The annual meeting of the Society for the Study of Reproduction in San Antonio, Texas; Biol Reprod (special issue): abstract #103, pp.99-100.

Cherry JA, Hou Xiaoying, Rueda BR, Davis JS, Townson DH 2008 Microvascular endothelial cells of the bovine corpus luteum: A comparative examination of the estrous cycle and pregnancy. Journal of Reproduction and Development 54(3): 183-191.

Yoon SY, Fissore RA. Release of phospholipase C zetaand [Ca2+]i oscillation-inducing activity during mammalian fertilization. Reproduction. 2007. 134:695-704.

Ross PJ, Beyhan Z, Iager AE, Yoon SY, Malcuit C, Schellander K, Fissore RA, Cibelli JB. Parthenogenetic activation of bovine oocytes using bovine and murine phospholipase C zeta. BMC Dev Biol. 2008. 8:16.

Wurst A. K., A. B. Dixon, and E. K. Inskeep. 2007. Lack of effect of transrectal ultrasonography with restraint on lambing rate and prolificacy in ewes, Theriogenology 68:1012-1016.

Goravanahally, M. P., A. Sen, E. K. Inskeep, and J.A. Flores. 2007. PKCe and an
increase in intracellular calcium concentration are necessary for PGF2± to inhibit LH-stimulated progesterone secretion in cultured bovine steroidogenic luteal cells. Reprod. Biol. Endocrinol. 5:37-43.

Lingenfelter, B.M., Dailey, R.A., Inskeep, E.K., Vernon, M.W., Poole, D.H., Rhinehart, J.D. and Yao, J. 2007. Microarray analysis of gene expression in granulosal cells from persistent follicles in cattle. Anim. Reprod. Sci. 104:405-413.

Doerr, M. D, M. P. Goravanahally, J. D. Rhinehart, E. K. Inskeep and J. A. Flores. 2008. Effects of endothelin receptor type-A and type-B antagonists on prostaglandin F2&-induced luteolysis of the sheep corpus luteum. Biol. Reprod. 78:688-696.

Wurst, Aimee Kathryn 2007. Effects of Ovulation of Aged Follicles, Pregnancy Diagnosis By Ultrasonography, and Treatments During Lactation On Reproduction in Ewes, Dissertation, West Virginia University, [On-line Abstract].

Available: https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5347

Lingenfelter, Brandon Michael (2008). The Effect of Follicular Aging on Gene
Expression in oocytes and Granulosal Cells, Dissertation, West Virginia University, [On-line Abstract].

Available: https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5783

Davis, TL and Pate, JL. 2007. Proliferation of major histocompatibility nonrestricted gamma delta T cells is stimulated by bovine luteal cells. Biol. Reprod. 77:914-922

Hou, X., Arvisais, E.W., Jiang, C., Chen, D, Roy, S.K., Pate, J.L., Hansen, T.R., Rueda, B.R. and Davis, J.S. 2008. Prostaglandin F2± (PGF2±) stimulates the expression and secretion of TGFB1via induction of the early growth response 1 gene (EGR1) in the bovine corpus luteum. Mol. Endocrinol. 22:403-414

06/19/2009

Stevenson, JS, Tifany SM, Inskeep EK. Maintenance of pregnancy in dairy cattle after treatment with human chorionic gonadotropin or gonadotropin-releasing hormone. J. Dairy Sci 2008. 91:3092-3101.

Rhinehart JD, Starbuck-CLemmer MJ, Flores JA, Milvae RA, Yao J, Poole DH, Inskeep EK. Low peripheral progesterone and late embryonic / early fetal loss in sucked beef and lactating dairy cows. Theriogenology 2008; 71:480-490.

Devonish, EH, Knights, M, Inskeep, EK. Effect of expected peripheral concentration of progesterone on ovulation rate and litter size in Barbados Black berry ewes. Sheep and Goat Research Journal 2009; 24:17-25.

Jordan, KM, Inskeep EK, Knights M. Use of gonadotropin releasing hormone to inprove reproductive responses of ewes introduced to rams during seasonal anestrus. Anim Reprodu Sci 2009;

Goravanahally, MP, Salem M, Yao J, Inskeep EK, Flores JA. Differential gene expression in the bovine corpus luteum during transition from early phase to midphase and its potential role in acquisition of luteolytic sensitivity to prostaglandin F2 alpha. Biol Reprod 2009; 80:980-988.

Odhiambo, JF, Poole DH, Hughes L, DeJarnette Jm, Inskeep EK, Dailey RA. Pregnancy outcome in dairy and beef cattle after artificial insemination and treatment with seminal plasma or transforming growth factor beta-1.
http://dx.doi.org/10.1016/j.theriogenology.2009.04.013.

Jyothsma T, Lee KB, Tripurani SW, Smith GW, Yao J. Role of importin alpha 8, a new member of the importinalpha family of nuclear transport proteins, in early embryonic development in cattle. 2009 DOI: 10.1095/biolreprod.109.077396.

Keator CS, Hoagland TA, McCracken Ja, Milvae RA. Intrauterine infusion of BA-610, an endothelin type A receptor antagonist, delays luteolysis in dairy heifers. Dom Anim Endocr 2008; 34:411-418.

Rhinehart JD, Starbuck-Clemmer MJ, Flores JA, Milvae RA, Poole DH, Inskeep EK. Low peripheral progesterone and late embryonic / early fetal loss in sucked beef cows and lactaging dairy cows. Theriogenology 2009; 71:480-490.

Casale P. Luteolytic effects of endothelin-1 in the ewe. MS Thesis, U of Connecticut, 2009.

Camp M. The role of nitric oxide in ovine luteolysis. MS Thesis, University of Connecticut 2009.

Cherry JA, Xiaoying H, Rueda BR, Davis JS, Townson Dh. Microvascular endothelial cells of the bovine corpus luteum: A comparative examination of the estrous cycle and pregnancy. Journal of Reproduction and Development 2008. 54: 183-191.

Ferguson DE. Temporal expression of progesterone and proteins associated with prostaglandin F2-alpha-induced luteolysis in the sheep. MS Thesis, University of New Hampshire, 2009.

Sa Filho oG, Lemley CO, Wilson ME, Hillegass J, Vasconcelos JLM, Butler WR,. Relationships between dry matter intake (DMI), plasma progesterone (P4), and liver catabolic enzymes in lactating dairy cows. Abstract accepted for presentation at Joint Annual Meeting ADSA/ASAS, Montreal, Canada, July 2009.

Castaneda-Gutierrez E, Pelton SH, Giolbert RO, Buter WR. Effect of peripartum dietary energy supplementation of dairy cows on metabolites, liver function and reproductive variables. Anim Reprod Sci 2009; 112: 301-315.

Yang MY, Muruvi W, Fortune JE. Effects of steroids and kit ligand / kit on follicle formation in fetal bovine ovaries in vitro. Biology of Reproduction 2009; Special issue, proc of the 42nd annual meetin of the society for the study of reproduction.

Muruvi, W, Fortune JE. Kit ligand-KIT interaction is required for follicle activation and mediates insulin-stimulated activation of bovine primordial follicles in vitro. Biology of Reproduction 2009; Special issue, proceedings of the 42nd annual meeting of the society for the study of reproduction.

Souza Ah, Gumen A, Silva EP, Cunha AP, Guenther JN, Peto CM, Caraviello DZ, Wiltbank MC. Supplementation with estradiol-17-b before the last gonadotropin-releasing hormone injection of the ovsynch protocol in lactating diary cows. Journal of Dairy Science 2007; 90:4623-34.

Silva E, STerry RA, Kilb D, Wiltbank MC< Fricke PM. Effect of pretreatment with prostaglandin F2Alpha before resynchronization of ovulation on fertility of lactating dairy cows. Journal of Dairy Science 2007; 90: 5509-5517.

Souza Ah, Sartori R, Guenther JN, Caraviello D, Monson R, Wilbank MC. Effect of semen source and dose of FSH on superovulatory response and embryo production in Holstein heifers. Animal Reproduction 2008; 4:70-76.

Brusveen DJ, Cunha AP, Silva CD, Cunha PM, STerry RA, Silva EPB, Guenther JN, Wiltbank MC. Altering the time of the second gonadotropin-releasing hormone injection and artificial insemination during ovsynch affects pregnancies per AI in lactating dairy cows. Journal of Dairy Sciences 2008 91:1044-1052.

Souza AH, Ayres H, Ferreira RM, Wiltbank MC. A new presynchronization system (double-ovsynch( increases fertility at first postpartumtime AI in lactating diary cows. Theriogenology 80:208-15.

Stevenson JS< Tenouse DE, Krisher RL, Lamb GC, Dahlen CR, Pursley JR, Bello NM, Fricke PM, Wiltbank MC, Brusveen DJ, Burkhart M, Yougqist RS, Garverick HA. Detection of anovulation by heatmount detectors and transrectal ultrasonography before treatment with progesterone in a timed insemination protocol. Jounral of Dairy Science 2008; 91:2901-2915.

Silva C*, Wood JR*, Salvador L, Kostetskii I, Williams CJ, and Strauss JF 3rd (2009) Expression profile of male germ cell-associated genes in mouse embryonic stem cell cultures treated with all-trans retinoic acid and testosterone, Mol Reprod Dev, 76(1) 11-21, *authors contributed equally to the manuscript

JR, Slattery R, Clopton DT, Smith J, Beavers KA, Pohlmeier W, Bergman JW, Moline KV, Cupp AS (2009) Reproductive Ageing Influences Ovarian Function in Beef Cows, University of Nebraska Beef Report, in press

Wood JR, Yang Z, Mack EM, Cockerill KA, Hofman LA, and Smith JE (2008) Expression profile of MTOC-associated genes and growth factors in the ovary, Nebraska Physiological Society 11th Annual Meeting, Omaha, NE

Slattery R, Clopton D, Wood JR, Cushman R, and Cupp A (2009) Vascular endothelial growth factor (VEGF) mRNA isoforms are altered in bovine granulosa cells (GC) by circulating progestin concentrations (P4) and may indicate follicle status and ooctye competence Midwest Animal Science Annual Meeting (J. Animal Science) 87 (Supp 1) 85

Cushman RA, Wood JR, Echternkamp SE, and Cupp AS (2009) Influence of exogenous progestin on ovarian function in beef cows. Midwest Animal Science Annual Meeting (J. Animal Science) 87 (Supp 1) 239.

Smith JE, Yang Z, Yaw T, and Wood JR (2009) IGF-1 Dependent Changes in Histone H3 Modifications are Associated with Akt Signaling and the Expression of Cell Survival Genes, Society for the Study of Reproduction 42nd Annual Meeting, Pittsburgh, PA

Davis, TL and Pate, JL. 2007. Proliferation of major histocompatibility nonrestricted gamma delta T cells is stimulated by bovine luteal cells. Biol. Reprod. 77:914-922

Hou, X., Arvisais, E.W., Jiang, C., Chen, D, Roy, S.K., Pate, J.L., Hansen, T.R., Rueda, B.R. and Davis, J.S. 2008. Prostaglandin F2a (PGF2a) stimulates the expression and secretion of TGFB1via induction of the early growth response 1 gene (EGR1) in the bovine corpus luteum. Mol. Endocrinol. 22:403-414

Ndiaye, K, Poole, DH and Pate, JL. 2008. Expression and regulation of functional oxytocin receptors in bovine T lymphocytes. Biol. Reprod. 78:786-793

Winkelman, LA, Elsasser, TH, Lucy, MC, Pate, JL and Reynolds, CK. 2008. Suppressor of cytokine signaling-2 mRNA increases after parturition in the liver of dairy cows. J. Dairy Sci. 91:1080-1086

Ndiaye, K., Lussier, J. and Pate, J.L. 2008. Characterization of DER1-Like Domain Family Member 1 (DERL1) and its Expression in Bovine Corpus Luteum. World Congress on Reproductive Biology, abstract, no. 19.

Poole, D.H., Ndiaye, K., Pate, J.L., 2008. Prostaglandin F2a induces proinflammatory T lymphocyte phenotypes in the bovine corpus luteum. Biol Reprod. Abstracts, no. 609

Poole, D.H., Ndiaye, K., Pate, J.L., 2008. Potential role of secreted phosphoprotein 1 in the bovine corpus luteum. World Congress on Reproductive Biology, abstract no. 34

Ndiaye, K., Poole, D.H., Hansen, T.R., Pate, J.L., 2008. Expression profiles of cytokine and progesterone receptor messenger ribonucleic acids (mRNA) in bovine corpus luteum during pregnancy. Biol. Reprod. Abstract no. 400

06/11/2010

1. Piccinato CA, Sartori R, Sangsritavong S, Souza AH, Grummer RR, Luchini D, Wiltbank MC. 2010. In vitro and in vivo analysis of fatty acid effects on metabolisms of 17 beta-estradiol and progesterone in dairy cows. Journal of Dairy Science 93:1934-1943.

2. Araujo RR, Ginther OJ, Ferreira JC, Palhao MM, Beg MA, Wiltbank MC, 2009. Role of follicular estradiol-17² in determining the time of luteolysis in heifers. Biology of Reproduction PMID 19264702. Mar 4.

3. Souza AH, Cunha AP, Silva EPB, Gumen A, Ayres H, Guenther JN, Wiltbank MC, 2009. Comparison of gonadorelin products in lactating dairy cows: efficacy based on induction of ovulation of an accessory follicle and circulating LH profiles. Theriogenology 72:271-279.

4. Brusveen DJ, Souza AH, Wiltbank MC, 2009. Effects of additional prostaglandin F2± and estradiol-17² during Ovsynch in lactating dairy cows. Journal of Dairy Science 92: 1412-1422.

5. Souza AH, Viechnieski S, Lima FA, Silva FF, Araujo R, Bo GA, Wiltbank MC, Baruselli PS, 2009. Effects of equine chorionic gonadotropin and type of ovulatory stimulus in a time-AI protocol on reproductive responses in dairy cows. Theriogenology 72:10-21.

6. Bamber RL, Shook GE, Wiltbank MC, Santos JE, Fricke PM, 2009. Genetic parameters for anovulation and pregnancy loss in dairy cattle. Journal of Dairy Science 92:5739-5753.

7. Watters RD, Wiltbank MC, Guenther JN, Brickner AE, Rastani RR, Fricke PM, Grummer RR, 2009. Effect of dry period length on reproduction during the subsequent lactation. Journal of Dairy Science 92:3081-3090.

8. Checua CM, Beg MA, Gastal MO, Wiltbank MC, Parrish JJ, Ginther OJ, 2009. Effect of suppression of FSH with a GnRH antagonist (acyline) before and during follicle deviation in the mare. Reproduction in Domestic Animal 44:504-511.

9. Watters, RD, Wiltbank, MC, Guenther JN, Brickner AE, Rastani RR, Fricke PM, Grummer RR, 2009. Effects of dry period length on reproduction during the subsequent lactation. Journal of Dairy Science 92: 3081-3090.

10. Kneebone J, Tsang PCW, Townson DH. 2010 IDEXX SNAP® tests detect antibiotic residues in powered milk products. Journal of Dairy Science, Accepted

11. Townson DH, Putnam AN, Sullivan BT, Guo L, Irving-Rodgers HF, 2010. Expression and distribution of cytokeratin 8/19 intermediate filaments in bovine antral follicles and corpus luteum: An intrinsic mechanism of resistance to apoptosis? Histology and Histopathology 25:889-900

12. Duncan AR, 2009. Disruption of cytokeratin 18-containing intermediate filaments in bovine luteal cells: Effects on Fas expression, progesterone secretion, and FasL-induced apoptosis. MS Thesis, University of New Hampshire.

13. Forcina JJ, 2009. Genetic over-expression of cytokeratin 18 in bovine luteal cells: Effects on intermediate filament formation and Fas ligand-induced apoptosis. MS Thesis, University of New Hampshire.

14. Cushman RA, Wood JR, Slattery R, Clopton DT, Smith J, Beavers KA, Pohlmeier W, Bergman JW, Moline KV, Cupp AS (2010) Reproductive Ageing Influences Ovarian Function in Beef Cows, University of Nebraska Beef Report, p16

15. Cooney MA, Malcuit C, Banyoon C, Holland MK, Fissore RA, DCurz NT (2010) Species-Specific Differences In Activity and Nuclear Localization of Murine and Bovine Phospholipase C, Zeta 1. Biol Reprod 83(1):92-101.

16. Tripurani, S.K., Xiao, C., Salem, M. and Yao, J. 2010. Cloning and analysis of fetal ovary microRNAs in cattle. Animal Reproduction Science. 120:16-22.

17. Odhiambo JF, Poole DH, Hughes L, DeJarnette JM, Inskeep EK, Dailey RA. 2009. Pregnancy outcome in dairy and beef cattle after artificial insemination and treatment with seminal plasma or transforming growth factor beta-1. Theriogenology. 72: 566-571.

18. Inskeep K. 2009. Induction of estrus as a reproductive management tool in anestrous ewes. Proceedings Great Lakes Dairy Sheep Symposium. Ed by DL Thomas. Albany NY Nov 12-14, 2009. pp 94-110.

19. Perea-Ganchou F, Inskeep EK. 2010. Infertilidad asociada con la duracion de la fase luteal en vacas postparto. In Manejo Reproductivo de la Vaca Posparto. Ed by German E. Portillo Martinez. Cuadernos Cientificos Girarz 7:205-221. Maracaibo, Venezuala.

20. Inskeep EK. 2010. Time-dependent embryotoxicity of the endogenous luteolysin prostaglandin F2± in ruminants. Chapter 10, pp 240-255 in Endocrine Toxicology. C. Eldridge and J.T. Stevens, Eds. Informa Healthcare, London

21. Inskeep EK, Dailey RA. 2010. Maximizing Embryonic and Early Fetal Survival in Dairy Cattle. In WCDS Advances inDairy Technology 22:51-69. Lorraine Doepel, Editor.

22. Relling, AE, Pate, JL, Reynolds, CK and Loerch, SC. 2010. Effect of feed restriction and supplemental dietary fat on gut peptide and hypothalamic neuropeptide mRNA concentrations in growing wethers. J. Anim. Sci. 88: 737-748

23. Ndiaye, K, Lussier, JG, and Pate, JL. 2010. Molecular characterization and expression of DERL1 in bovine ovarian follicles and corpora lutea. Reprod. Biol. Endocrinol. 8:94 (http://www.rbej.com/content/8/1/94)

24. Pate, JL, Toyokawa, K, Walusimbi, S, and Brzezicka, E. 2010. The Interface of the Immune and Reproductive Systems in the Ovary: Lessons Learned from the Corpus Luteum of Domestic Animal Models. Amer. J. Reprod. Immunol. 64:275-286.

25. Smitz, J., R.L. Stouffer, E.E. Telfer, T.K. Woodruff, M.B. Zelinski, M.M. Dolmans, J. Donnez, J.E. Fortune, O. Hovatta, K. Jewgenow, H.M. Picton, C. Plancha, L.D. Shea, 2010. Current achievements and future research directions in ovarian tissue culture, in-vitro follicle development and transplantation: Implications for fertility preservation. Human Reproduction Update 16:395-414.

26. Fortune, J.E., M.Y. Yang, and W. Muruvi, 2010. The earliest stages of follicular development: Follicle formation and activation. Reproduction in Domestic Ruminants VII, M.C. Lucy, J.L. Pate, M.F, Smith, and T.E. Spencer (eds). Nottingham Univ. Press, Nottingham, UK, p. 203-216.

06/11/2011

1. Mack EM, Smith JE, and Wood JR. IGF-1 has an Additive Effect on cAMP-Dependent Regulation of Granulosa Cell Gene Expression through Activation of Akt- and Erk1/2 Signaling, (submitted to Molecular Cellular Endocrinology)

2. Slattery RG, WE Pohlmeier, RM McFee, JG Kerl, VM Brauer, JR Wood, RA Cushman, AS Cupp. Females with low granulosa cell efficiency have excess follicular fluid androstenedione, reduced IGF-1 mRNA, greater expression of mRNA for VEGFA164b and reduced follicle health and fertility. (submitted to Reproduction)

3. Artec RA, Pohlmeier WE, McFee RM, Brauer V, Wood JR, Cushman R, and Cupp AS. Anti-angiogenic VEGFA164B isoform mRNA is more abundant in E2-inactive, atretic follicles while expression of angiogenic VEGFA isoforms is greater in granulosa cells from developing bovine follicles prior to the LH surge. (Submitted to Reproduction).

4. *Zhang B, *Tsang PCW, Pate JL, Moses MA 2011. A role for cysteine rich 61 in the angiogenic switch during the estrous cycle in cows: Regulation by prostaglandin F 2alpha. Biology of Reproduction. In Press. *These authors contributed equally to this work.

5. Sullivan BT, Cherry JA, Sakamoto H, Henkes LE, Townson DH, Rueda BR 2010 Cytokeratin-18 (CK18) expression inhibits cytokine-induced death of cervical cancer cells. International Journal of Gynecologic Cancer 20:1474-1481.

6. Galvao, K. N., M. Frajblat, W. R. Butler, S. B. Brittin, C. L. Guard, and R. O. Gilbert. Effect of early postpartum ovulation on fertility in dairy cows. Reprod. Dom. Anim., doi: 10.1111/j.1439-0531.2009.01517. 2009.

7. Yang JH, Menshenina J, Cunha GR, and Place N, Baskin LS. (2010). Morphology of mouse external genitalia: implications for a role of estrogen in sexual dimorphism of the mouse genital tubercle. J Urol. 184:1604-1609.

8. Piekarski DJ, Place NJ, and Zucker I. (2010). Facilitation of male sexual behavior in Syrian hamsters by the combined action of dihydrotestosterone and testosterone. PLoS ONE. 5(9):e12749.

9. Place NJ, Coscia EM, Dahl NJ, Drea CM, Holekamp KE, Roser JF Sisk CL, Weldele ML, and Glickman SE. (2011). The anti-androgen combination, flutamide plus finasteride paradoxically suppressed LH and androgen concentrations in pregnant spotted hyenas, but not in males. Gen Comp Endocrinol. 170:455-459.

10. Place NJ, Hansen BS, Cheraskin J-L, Cudney SE, Flanders JA, Newmark AD, Barry B, and Scarlett JM. (2011). Measurement of serum anti-Müllerian hormone concentrations in female dogs and cats before and after ovarihysterectomy. J Vet Diag Invest 23:524-527.

11. Schwacke LH, Zolman ES, Balmer BC, DeGuise S, George RC, Hoguet J, Hohn AA, Kucklick JR, Lamb S, Levin M, Litz JA, McFee WE, Place NJ, Townsend FI, Welss RS, and Rowles TK. (2011). Anemia, hypothyroidism, and immune suppression associated with polychlorinated biphenyl exposure in bottlenose dolphins (Tursiops truncatus) Proc Roy Soc B (in press).

12. Almeida J, Ball BA, Conley AJ, Place NJ, Liu IKM, Scholtz EL, Mathewson L, Stanley SD, and Moeller BC. (2011). Biological and clinical significance of anti-Müllerian hormone determination in blood serum of the mare. Theriogenology (in press).

13. Rutkowska J, Place NJ, Vincent SE and Adkins-Regan E. (2011). Adrenocortical response to mating, social interaction and restraint in the Japanese quail. Physiol Behav (in press).

14. Smitz, J., R.L. Stouffer, E.E. Telfer, T.K. Woodruff, M.B. Zelinski, M.M. Dolmans, J. Donnez, J.E. Fortune, O. Hovatta, K. Jewgenow, H.M. Picton, C. Plancha, L.D. Shea, 2010. Current achievements and future research directions in ovarian tissue culture, in-vitro follicle development and transplantation : Implications for fertility preservation. Human Reproduction Update 16:395-414.

15. Fortune, J.E., M.Y. Yang, and W. Muruvi, 2010. The earliest stages of follicular development: Follicle formation and activation. Reproduction in Domestic Ruminants VII, M.C. Lucy, J.L. Pate, M.F, Smith, and T.E. Spencer (eds). Nottingham Univ. Press, Nottingham, UK, p. 203-216.

16. Fortune, J.E., M.Y. Yang, and W. Muruvi, 2011. In vitro and in vivo regulation of follicular formation and activation in cattle. Reproduction, Fertility and Development 23:15-22.

17. Scaramuzzi, R.J., D.T. Baird, B.K. Campbell, M.-A. Driancourt, J. Dupont, J.E. Fortune, R.B. Gilchrist, G.B. Martin, K.P. McNatty, A.S. McNeilly, P. Monget, D. Monniaux, C. Vinoles Gil, R. Webb, 2011. Regulation of folliculogenesis and the determination of ovulation rate in ruminant. Reproduction, Fertility, and Development 23: 444-467.

18. Relling, AE, Pate, JL, Reynolds, CK and Loerch, SC. 2010. Effect of feed restriction and supplemental dietary fat on gut peptide and hypothalamic neuropeptide mRNA concentrations in growing wethers. J. Anim. Sci. 88: 737-748

19. Ndiaye, K, Lussier, JG, and Pate, JL. 2010. Molecular characterization and expression of DERL1 in bovine ovarian follicles and corpora lutea. Reprod. Biol. Endocrinol. 8:94 (http://www.rbej.com/content/8/1/94)

20. Pate, JL, Toyokawa, K, Walusimbi, S, and Brzezicka, E. 2010. The Interface of the Immune and Reproductive Systems in the Ovary: Lessons Learned from the Corpus Luteum of Domestic Animal Models. Amer. J. Reprod. Immunol. 64:275-286.

21. Pickworth, CL, Poole, DH, Velleman, SG, Pate, JL, Loerch, SC, Fluharty, F L 2010. Adipogenic differentiation state-specific gene expression as related to bovine carcass adiposity. J Anim Sci. 2010 Oct 15. [Epub ahead of print]

22. Lucy, MC, Pate, JL Smith, MF and Spencer, TE, eds. 2010. Reproduction in Domestic Ruminants VII. Society of Reproduction and Fertility Volume 67. Nottingham University Press.

23. Tripurani, S.K., Lee, K.B., Wee, G., Smith, G.W., and Yao, J. 2011. MicroRNA-196a regulates bovine newborn ovary homeobox gene (NOBOX) expression during early embryogenesis. BMC Developmental Biology 11:25. doi:10.1186/1471-213X-11-25.

24. Tripurani, S.K., Lee, K.B., Wang, L.,Wee, G., Smith, G.W., Lee, Y.S., Latham, K.E. and Yao, J. 2011. A Novel Functional Role for the Oocyte-Specific Transcription Factor Newborn Ovary Homeobox (NOBOX) during Early Embryonic Development in Cattle. Endocrinology. 152:1013-1023.

25. Inskeep, E.K. 2011. Ruminant reproduction: recent findings and future challenges, a summary. In: Reproduction in Domestic Ruminants VII. M.F. Smith, M. Lucy and T. Spencer, Eds. 12 pp.

07/05/2012

Abstracts

Tripurani, S.K., Wang, L., Lee, K.B., Gabbine, W., Smith, G.W. and Yao, J. The SUMO-conjugating enzyme Ubc9 is developmentally regulated and interacts with activating transcription factor 7 interacting protein 2 (ATF7IP2) in cattle. 44th Annual Meeting Society for the Study of Reproduction, Portland, Oregon. July 31 - August 4, 2011.

Tripurani, S.K., Lee, K.B., Smith, G.W. and Yao, J. Cloning and expression of bovine factor in the germline alpha (FIGLA) in oocytes and early embryos: a potential target of microRNA-212. 37th Annual Conference of the International Embryo Transfer Society, Orlando, Florida. January 8-11, 2011.

Walusimbi, SS and Pate, JL. 2011. Luteal cells establish contact with T lymphocytes via the T cell receptor and induce deletion of gamma-delta T cells with a proinflammatory phenotype. SSR Abstract #76

Brzezicka, E. and Pate, J.L. 2011. Luteal cells induce gamma delta T cell activation through secretory factors. SSR Abstract #222

Maalouf, SW, Smith, CL and Pate, JL. 2011. MicroRNA in the development of the corpus luteum. SSR Abstract #228

Toyokawa, K, Liu, W and Pate, JL. 2011. Expression and regulation of PRAME in the bovine corpus luteum. SSR Abstract #221

Summers A, Cushman R, Smith JE, Lammers B, McFee R, Pohlmeier W, Brauer V, Sargent K, Lu N, Cupp AS, Wood JR (2011) Females with reduced fertility have excess androstenedione in follicular fluid, altered theca gene expression and increased VEGFA164b, maternal effect, and microRNA processing mRNA levels in cumulus-oocyte complexes, Society for the Study of Reproduction 43rd Annual Meeting, Portland, OR

Wood JR, Yang Z, and Smith JE (2011) Genes involved in the immediate early response and epithelial mesenchymal transition are regulated by adipocytokines in the female reproductive tract, Society for the Study of Reproduction 43rd Annual Meeting, Portland, OR

Schneider, A., L. F. M. Pfeifer, M. N. Corrêa, and W. R. Butler. Difference in the expression of components of the GHR/IGF-I axis in follicular granulosa cells and corpus luteum in cows. J.Dairy Sci. 94(E-Suppl.1):595, 2011. (Abstract)

Esposito, G. and W. R. Butler. Effect of dietary conjugated linoleic acid on reproduction and tissue responses in dairy cows. J Dairy Sci. 94(E-Suppl.1):341, 2011. (Abstract)

Peer-Reviewed

Tripurani, S.K., Lee, K.B., Wee, G., Smith, G.W.. and Yao, J. 2011. MicroRNA-196a regulates bovine newborn ovary homeobox gene (NOBOX) expression during early embryogenesis. BMC Developmental Biology 11:25. doi:10.1186/1471-213X-11-25.

Tripurani, S.K., Lee, K.B., Wang, L.,Wee, G., Smith, G.W., Lee, Y.S., Latham, K.E. and Yao, J. 2011. A Novel Functional Role for the Oocyte-Specific Transcription Factor Newborn Ovary Homeobox (NOBOX) during Early Embryonic Development in Cattle. Endocrinology. 152:1013-1023.

Inskeep, E.K. 2011. Ruminant reproduction: recent findings and future challenges, a summary. In: Reproduction in Domestic Ruminants VII. M.F. Smith, M. Lucy and T. Spencer, Eds. 12 pp.

Tian X and Diaz FJ. Zinc depletion causes multiple defects in ovarian function during the periovulatory period. Endocrinology: (2012) 153:873-886.

Pickworth, CL, Poole, DH, Velleman, SG, Pate, JL, Loerch, SC, Fluharty, F L 2011. Adipogenic differentiation state-specific gene expression as related to bovine carcass adiposity. J Anim Sci. 89:355-366.

Poole, DH and Pate, JL. 2012. Luteal microenvironment directs resident T lymphocyte function. Biol. Reprod. 86(2)29:1-10.

Pate, JL. 2012. Commentary: It takes two to tango but four for the finale. Biol. Reprod. Doi:10.1095/biolreprod 112.099150.

Pate, JL. Johnson-Larson, C.J., Ottobre, J.S. Life or Death decisions in the corpus luteum. Reprod. Domest. Anim. (in press)

*Zhang B, *Tsang PCW, Pate JL, Moses MA 2011. A role for cysteine-rich 61 in the angiogenic switch during the estrous cycle in cows: Regulation by prostaglandin F 2alpha. Biology of Reproduction 85:261-268 *These authors contributed equally to this work.

Townson DH, Combelles CMH 2012 Ovarian Follicular Atresia. In: Basic Gynecology  Some Related Issues, In Tech Publishing, Atef Darwish (Ed), Rijeka, Croatia. pp. 43-76. ISBN 978-953-51-0166-6.

McCracken JA, Custer EE, Schreiber DT, Tsang PCW, Keator CS, Arosh JA 2012. A new in vivo model for luteolysis using systemic pulsatile infusions of PGF2±. Prostaglandins and Other Lipid Mediators 97:90-96.

Yang Z, Norwood KA, Kerl JG, and Wood JR (2012) Genes Involved in the Immediate Early Response and Epithelial-Mesenchymal Transition are Regulated by Adipocytokines in the Female Reproductive Tract, Mol Reprod Dev 79(2): 128-137 PMID: 22128093

Mack EM, Smith JE, and Wood JR (2012) IGF1 has an Additive Effect on cAMP-Dependent Regulation of Granulosa Cell Ovulatory Response Genes through Activation of Akt- and Erk1/2 Signaling, Reproduction (submitted 6/2012)

Extension Bulletins

Lu N*, Smith JE*, Brauer V, Summers A, Pohlmeier W, Beavers KA, McFee R, Sargent K, Kerl JG, Cushman RA, Cupp AS, Wood JR (2012) Oocyte mRNA and Follicle Androgen Levels are Associated with Fertility, Nebraska 2012 Beef Cattle Report, p.28 *authors contributed equally to the manuscript

Theses/Dissertations

Current Funding

USDA Proposal number: 2009-01853 - Jorge Flores
Proposal Title: Regulation of Corpus Luteum Lifespan: Developmental Differences in Signal Transduction Mechanisms Associated with the Luteal PGF2alpha Receptor, Total Direct and indirect costs: $338,416.

USDA Proposal number: 2009-01853 - Jianbo Yao
Proposal Title: Functional Characterization of Bovine Importin ±8, A New Member of the Importin ± Family Specifically Expressed in Oocytes and Early Embryos, Total Direct and indirect costs: $347,000.



WV -140 Out-of-Season Breeding in Sheep, West Virginia State Legislature - E. K. Inskeep, P. E. Lewis, Marlon Knights, Direct Costs: $86,000 per year

Increasing Adoption of Out-of-Season Breeding to Enhance Profitability of Sheep Producers in West Virginia GNE11-015, USDA/SARE GRAD/ EXT/COM Award Knights, M & D'Souza, K, 8/1/2011- 7/30/2012 $14,999.00

In-Kind Donation (2012) - 1250 CIDR-G Inserts (Retail Value $5.00 each) - Pfizer Animal Health - E. K. Inskeep and M. Knights $6,250.00

National Research Initiative Competitive Grant no. 2008-35203-04617 from the USDA National Institute of Food and Agriculture to JL Pate

NRICGP/USDA Grant #2007-35203-18074,"Role of Cytokeratin 8/18 Filaments in Fas Ligand-Induced Apoptosis of Ovarian Steroidogenic Cells". D. Townson

USDA (NRICGP, #2008-35203-05989); 9/30/09-8/31/012; PI - 15% effort, "Effects of Fetal Steroids on the Formation of Ovarian Follicles and on their Competence to Initiate Growth", JE Fortune

NIH (R21 HD0602322); 07/01/09- 06/30/13; PI  20% effort, "Effects of Fetal Steroids on the Formation of Bovine Ovarian Follicles and on their Competence to Initiate Growth", JE Fortune