NC1167: N-3 Polyunsaturated Fatty Acids and Human Health and Disease (NC167)

(Multistate Research Project)

Status: Inactive/Terminating

SAES-422 Reports

03/01/2004

Turek, J.J., Watkins, B.A., Schoenlein, I.A., Allen, K.G.D., Hayek, M.G. and Aldrich, C.G. Oxidized lipids depress canine growth, immune function, and bone formation. J. Nutr. Biochem. 14: 24-31, 2003.





Yu, L., Perret, J., Parker,T. and Allen, K.G.D. Enzymatic modification to improve the water-absorbing and gelling properties of psyllium. Food Chem. 82: 243-248, 2003.





Watkins, B.A., Li, Y., Romsos, D.R., Hoffman, W.E., Allen, K.G.D. and Seifert, M.F. CLA and Bone Modeling in Rats. In: Advances in Conjugated Linoleic Acid Research, Volume 2, pp 218-250 (Sebedio, J-L., Christie, W.W. and Adlof, R. Eds.) American Oil Chemists Society (AOCS) Press, Champaign IL, 2003.





Allen, K.G.D., Perez, M.A., Hansen, R.A. and Harris, M.A. N-3 fatty acids alter eicosanoid and matrix metalloproteinase mediators of parturition in rats. Presented at Experimental Biology 2003 Meeting, San Diego, CA, April 11-15, 2003. FASEB J. 17, A1118 (Abstract # 695.1), 2003.



Hansen, R.A. Short term effects of dietary fish oil on matrix metalloproteinases in dogs with anterior cruciate ligament disease. PhD Dissertation, Colorado State University, Fort Collins, CO, Summer 2003.



Seal, S.J. Circulating PGE2 and PGF2? metabolite and long chain polyunsaturated fatty acid levels in full term pregnancy with docosahexaenoic acid supplementation. Masters Thesis, Colorado State University, Fort Collins, CO, Spring 2003.



Hansen, R.A., Allen, K.G.D., Pluhar, E.G., Ogilvie, G.K., Fettman, M.J. and Harris, M.A. N-3 fatty acids decrease inflammatory mediators in arthritic dogs. Presented at Experimental Biology 2003 Meeting, San Diego, CA, April 11-15, 2003. FASEB J. 17, A330 (Abstract # 200.3), 2003.





Allen, K.G.D. A role for dietary n-3 fatty acids in gestational length. Presented at The Institute of Food Technologists (IFT) Annual Meeting and Food Expo, July 12-16, 2003, Chicago IL, as part of Session 82: Symposium on Dietary n-6/n-3 Fatty Acid Balance. Abstract 82-3, page 207 of 2003 IFT Annual Meeting Technical Program Abstracts.





Lee, J-Y., Lewis, N.M., Scheideler, S.E., Carr, T.P. 2003. Consumption of omega-3 fatty acid enriched eggs and serum lipids in humans. Journal of Nutraceuticals, Functional and Medical Foods. 4(1):3-13.





Lewis, N., Plugge, S., Eskridge, K., Wander, R.C. 2003. Serum ALA increases with inclusion of one omega-3 enriched egg in the diet. The FASEB J. 17:A336.





Al-Numair, Khalid and Lewis, Nancy M. 2003. Variation in source and consumption of omega-3 fatty acids in two different population groups in Saudi Arabia. 5th International Food Data Conference and 27th National Nutrient Databank Conference, Washington, D.C., Proceedings, p. 85.





Heidal, Kimberly. 2003. Evaluating the effects of a nutrition education program on the consumption of omega-3 fatty acids for heart patients. Ph.D. Dissertation, University of Nebraska, Lincoln, NE.





Lohse B, Shafer K. Problem-based learning is effective for extension education about omega-3 fats. Society for Nutrition Education Annual Conference Proceedings 36(1):33;2003.





Lohse B, Nitzke S, Ney D. Introducing a problem-based unit into a lifespan nutrition class using a randomized design produces equivocal outcomes. J Amer Diet Assoc. 103(8):1020-1025;2003.





Lohse Knous B, Nutritional Issues for Pharmacists: Dietary Supplements [Continuing Professional Education] 2003;29(4):1-23. Lawrence, KS:Pharmat, Inc.





Weigh to Diet. Lesson (MF2595) and Leader?s Guide (MF2596). August 2003.

http://www.oznet.ksu.edu/library/fntr2/MF2596.pdf

http://www.oznet.ksu.edu/library/fntr2/MF2595.pdf

12/14/2004

Allen, K.G.D., Bristow, S.J. and Yu, L. Hypolipidemic effects of modified psyllium preparations. J. Agric. Food Chem. 52: 4998-5003, 2004.

Irons, R., Anderson, M.J., Zhang, M. and Fritsche K.L. (2003) Dietary fish oil impairs primary host resistance against L. monocytogenes more than the immunological memory response. J. Nutr. 133: 1163-1169.


Zhang, M. and Fritsche K.L. (2004) Fatty acid-mediated inhibition of interleukin-12 production by murine macrophages is independent of peroxisome proliferator-activated receptor-g. Brit. J. Nutr. 91: 733-739.


Anderson M and Fritsche KL (2004) Dietary polyunsaturated fatty acids modulate in vivo, antigen-driven CD4+ T-cell proliferation in mice. J. Nutr. 134: 1978-1983.


Anderson, M. (2004) Dietary omega-3 polyunsaturated fatty acids and Th1 immunity. Ph.D. Dissertation, University of Missouri, Columbia, MO.


Irons, R. (2004) Fish oil severely impairs immunity to Listeria monocytogenes without affecting the adaptive immune response. Ph.D. Dissertation, University of Missouri, Columbia, MO.

Harkins, JM, Moustaid-Moussa, N, Penner, KM, Pestka, JJ, Chung, YJ, North, CM, and Claycombe, KJ. Expression of interleukin-6 is greater in preadipocytes than in adipocytes of 3T3-L1 cells and C57BL/6J and ob/ob mice. J Nutr. 134:2673-2677, 2004.


Harkins, JM, Whelan J, Jones L, Ken Allen, and Claycombe, KJ. Inhibitory effect of SDA and EPA on 3T3-L1 preadipocyte secretion of interleukin-6 (IL-6). In preparation, 2004.

Sindelar, Carrie A., Lewis, Nancy M., Scheerger, Sarah B., Plugge, Sheri L., Eskridge, Kent M., and Wander, Rosemary C. 2004. Serum lipids of physically active adults consuming omega-3 fatty acid-enriched eggs or standard eggs. Nutrition Research 24:731-739.


Heidal, Kimberly, Lewis, Nancy, and Evans, Sharon. 2004. Survey of omega-3 food selections in heart patients living in the Midwest. Nutrition Research 24:741-747.


Heidal, Kimberly, Lewis, Nancy M. 2004. Omega-3 fatty acid nutrition education resources. Journal of Nutrition Education and Behavior 36 (4):209-210.
Al-Numair, Khalid and Lewis, Nancy M. 2004. Omega-3 fatty acid intake and incidence of nonfatal myocardial infarction differ between coastal and internal regions of Saudi Arabia. Ecology of Food and Nutrition 43:93-106.

Ciubotaru I, Lee YS, Wander. Dietary fish oil decrease C-reaction protein, interleukin-6, and triacylglycerol to HDL-cholesterol ratio in postmenopausal women on HRT. J Nutr Biochem. 2003 Sep;14(9):513-21.


Toobert DJ, Glasgow RE, Strycker LA, Barrera M Jr, Radcliffe JL, Wander RC, Bagdade JD. Biologic and quality-of-life outcomes from the Mediterranean Lifestyle Program: a randomized clinical trial. Diabetes Care. 2003 Aug;26(8):2288-93.


Hall JA, Tooley KA, Gradin JL, Jewell DE, Wander RC. Effects of dietary n-6 and n-3 fatty acids and vitamin E on the immune response of healthy geriatric dogs. Am J Vet Res. 2003 Jun;64(6):762-72.

Manns PJ, Williams DP, Snow CM, Wander RC. Physical activity, body fat, and serum C-reactive protein in postmenopausal women with and without hormone replacement. Am J Hum Biol. 2003 Jan-Feb;15(1):91-100.


Whelan, J. and McEntee, M.F. 2003. NSAIDs, Prostaglandins and APC-Driven Intestinal Tumorigenesis. In: Cyclooxygenase-2 Blockade in Cancer Prevention and Therapy (Ed., Harris, R.E.) Humana Press, Inc.. Totowa, NJ

D.W.L. Ma, J. Seo, L.A. Davidson, E.S. Callaway, Y.Y. Fan, J.R. Lupton and R.S. Chapkin. n-3 PUFA alter caveolae lipid composition and resident protein localization in mouse colon. Faseb Journal, April 2004, 10.1096/fj.03-0604fje, 18:1040-1042, 2004.


L.M. Sanders, C.E. Henderson, M.Y. Hong, R. Barhoumi, R.C. Burghardt, R.J. Carroll, N.D. Turner, R.S. Chapkin and J.R. Lupton. Pro-oxidant environment of the colon compared to the small intestine may contribute to greater cancer susceptibility. Cancer Letters 208:155-161, 2004.


K.C. Switzer, Y-Y. Fan, N. Wang, D.M. McMurray and R.S. Chapkin. Dietary n-3 polyunsaturated fatty acids promote activation-induced cell death in the Th1-polarized murine CD4+ T-cells. Journal of Lipid Research, 45:1482-1492, 2004.


L.A. Davidson, D.V. Nyuyen, R.M. Hokanson, E.S. Callaway, R.B. Isett, N.D. Turner, E.R. Dougherty, J.R. Lupton, R.J. Carroll and R.S. Chapkin. Chemopreventive n-3 polyunsaturated fatty acids reprogram genetic signatures during colon cancer initiation and progression in the rat. Cancer Research 64:6797-6804, 2004.








11/12/2005

Al-Numair, Khalid and Lewis, Nancy M. 2005. Omega-3 fatty acid consumption and food sources differ among elderly men living in coastal and internal regions of Saudi Arabia. Pakistan Journal of Nutrition 4(2):106-111. J. Series No. 14308.

Ritter-Gooder, P. and Lewis, Nancy M. 2005. Validity and reliability of a quantitative food frequency questionnaire measuring N-3 fatty acid intakes in cardiac patients in the rural Midwest. Journal of the American Dietetic Association 105:A16.

Ritter-Gooder, P. Validity and reliability of a quantitative food frequency questionnaire measuring omega-3 fatty acid intakes in cardiac patients in the Midwest. M.S. Thesis, University of Nebraska. 2005.

Troxell, H., Anderson, J., Auld, G., Marx, N., Harris, M.A., Reece M.S. and Allen, K.G.D. Omega-3 for Baby and Me: Material Development for a WIC intervention to Increase DHA Intake During Pregnancy. Maternal and Child Health Journal 9: 189-197, 2005.

Lohse B, Shafer KJ, Theory-driven n-3 polyunsaturated fatty acid education delivered by written correspondence and problem-based approaches. Nutrition Research. (In Press).

Jones, L. and Whelan, J., Human Equivalent Dose Modeling for Omega-3 Fatty Acid Supplementation in C57BL/6J Mice. 2005. FASEB J. 590.3A.

Irons, R and Fritsche K.L. (2005) Omega-3 polyunsaturated fatty acids impair in vivo interferon-gamma responsiveness via diminishing receptor signaling. J Infect Dis. 191(3): 481-6.

Irons, R., Pinge-Filho, P., Fritsche, K. (2005) Dietary (n-3) polyunsaturated fatty acids do not affect the in vivo development and function of Listeria-specific CD4+ and CD8+ effector and memory/effector T cells in mice. J. Nutr. 135: 1151-1156.

Fritsche, K., Irons, R., Pompos, L., Janes, J., Zheng Z. and Brown, C. (2005) Omega-3 polyunsaturated fatty acid impairment of early host resistance against Listeria monocytogenes infection is independent of neutrophil infiltration and function. Cell Immunol (in press)

Perez, M.A., Hansen, R.A., Harris, M.A. and Allen, K.G.D. Dietary docosahexaenoic acid alters pregnant rat reproductive tissue prostaglandin and matrix metalloproteinase production. J. Nutr. Biochem. In Press 2005.

Rose, Janelle R. Dietary stearidonic acid and pregnant rat uterine and fetal membrane mediators of premature delivery. Masters degree Thesis, Colorado State University. Fall Semester 2004.

Perez, Mark A. Dietary docosahexaenoic acid alters pregnant rat reproductive tissue prostaglandin and matrix metalloproteinase production. Masters degree Thesis, Colorado State University. Fall Semester 2005.

Krugman, J, Rowe T, Tonso E, Tonso T, Driscoll M, Clement B, Anderson L, Hirschi K, Rule DC, Culver B, and Broughton KS. 2005 Effect of stearidonic acid on eicosanoid metabolism and ovulation. FASEB J. 19:A1007 (590.2)

Harkins JM, Moustaid-Moussa N, Chung YJ, Penner KM, Pestka JJ, North CM, Claycombe KJ. Expression of interleukin-6 is greater in preadipocytes than in adipocytes of 3T3-L1 cells and C57BL/6J and ob/ob mice. J Nutr. 134(10):2673-2677, 2004

Ciubotaru, I., Potempa, L.A., and Wander, R.C. 2005. Production of modified C-reactive protein in U937-derived macrophages. Accepted Society Experimental Biology and Medicine.

Lee, Y.S. and Wander, R.C. 2005. Reduced effect on apoptosis of 4-hydroxyhexenal and oxidized LDL enriched with n-3 fatty acids from postmenopausal women. J Nutr. Biochem. Apr 16(4): 213-221.

Hall, J.A., Henry, L.R., Jha, S., Skinner, M.M., Jewell, D.E., and Wander, R.C. 2005. Dietary (n-3) fatty acids alter plasma fatty acids and leukotriene B synthesis by stimulated neutrophils from healthy geriatric Beagles. Prostaglandins, Leukotrienes, Essential Fatty Acids. Nov 73(5):335-41.

Irina Ciubotaru, Ph.D. 2005. The Anti-Inflammatory Effects of Eicosapentaenoic and Docosahexaenoic Acids found in Fish in vivo and in vitro. Thesis.

D.W.L. Ma, J. Seo, L.A. Davidson, E.S. Callaway, Y.Y. Fan, J.R. Lupton and R.S. Chapkin. n-3 PUFA alter caveolae lipid composition and resident protein localization in mouse colon. Faseb Journal, April 2004, 10.1096/fj.03-0604fje, 18:1040-1042, 2004.

D.W.L. Ma, J. Seo, K.C. Switzer, Y.Y. Fan, D.N. McMurray, J.R. Lupton and R.S. Chapkin. n-3 PUFA and membrane microdomains: a new frontier in bioactive lipid research. J Nutr Biochem 15: 700-706, 2004.

11/11/1111

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