07/23/2002

06/05/2003

INDIANA

Bidwell, C.A., M. Spurlock, and D. Moody. 2003. Serial analysis of gene expression of pig adipose and muscle tissue. Plant and Animal Genomes XI Conference, San Diego, CA. www.intl-pag.org/11/abstracts/P01_P69_XI.html.



IOWA

Berg, E. P., E. L. McFadin, K. R. Maddock, R. N. Goodwin, T. J. Baas, and D. H. Keisler. 2003. Serum concentrations of leptin in six genetic lines of swine and relationship with growth and carcass characteristics. J. Anim. Sci. 81:167-171.



Chaiwong, N., J.C.M. Dekkers, R.L. Fernando and M.F. Rothschild. 2003. Introgressing Multiple QTL through Backcross Breeding Programs. Swine Research Reports. Iowa State University.



Chen, P., T. J. Baas, J. W. Mabry, J. C. M. Dekkers, and K. J. Koehler. 2002. Genetic parameters and trends for lean growth rate and its components in U. S. Yorkshire, Duroc, Hampshire, and Landrace pigs. J. Anim. Sci. 80:2062-2070.



Chen, P., T. J. Baas, J. W. Mabry, J. C. M. Dekkers, and K. J. Koehler. 2003. Genetic parameters and trends for litter traits in U. S. Yorkshire, Duroc, Hampshire, and Landrace pigs. J. Anim. Sci. 81:46-53.



Ciobanu, D.C., S.M. Lonergan, M. Malek, J.R. Woollard, E.J. Lonergan and M.F. Rothschild. 2003. New Alleles in the Calpastatin Gene Associated with Improved Tenderness in Pigs. Swine Research Reports. Iowa State University



Crock, A.M., D.S. Casey, and J.C.M. Dekkers. 2003. Feeding behavior of finishing boars and gilts on electronic feeders. J. Anim. Sci. 81 (Suppl. 2):

Kim, K.S., N. T. Nguyen, J. M Reecy, L. L. Anderson, and M. F. Rothschild. 2003. Molecular genetic studies of porcine genes for obesity. Swine Research Reports. Iowa State University.



Kulak, K., J. Wilton, G. Fox and J. Dekkers. 2003. Comparisons of economic values with and without risk for livestock trait improvement Livestock Production Science, 79: 183-191.



Malek, M., D. C. Ciobanu, and M. F. Rothschild. 2003. Genetic and physical mapping of ACACB, PPP1CC and GPR49 genes on porcine chromosomes 5 and 14 help to define a break point on human chromosome 12. Proceedings Plant & Animal Genome XI meeting, January 11-15, San Diego, CA.



Moeller, S. J., T. J. Baas, T. D. Leeds, R. S. Emnett, and K. M. Irvin. 2003. Rendement Napole gene effects and a comparison of glycolytic potential and DNA genotyping for classification of Rendement Napole status in Hampshire-sired pigs. J. Anim. Sci. 81:402-410.



Newcom, D. W., T. J. Baas, and J. W. Lampe. 2002. Prediction of intramuscular fat percentage in live swine using real-time ultrasound. J. Anim. Sci. 80:3046-3052.



Newcom, D. W., T. J. Baas, and R. N. Goodwin. 2003. Relationship between intramuscular fat percentage predicted from real-time ultrasound and meat quality traits in pigs. Midwest ASAS Abstracts, p. 5.



Newcom, D. W., T. J. Baas, J. W. Mabry, and R. N. Goodwin. 2002. Genetic parameters for pork carcass components. J. Anim. Sci. 80:3099-3106.



Nguyen, N-T, K.-S. Kim, H. Thomsen, J. Helm and M. F. Rothschild 2003. Investigation of candidate gene for growth and fatness QTL on the pig chromosome 7. Proceedings Plant & Animal Genome XI meeting, January 11-15 San Diego, CA.



Otieno, C.J., S. Vleck, C. Jelks, K.-S. Kim, N. T. Nguyen and M. F. Rothschild. 2003. Mapping of diabetes-related genes in the pig. Proceedings Plant & Animal Genome XI meeting, January 11-15, San Diego, CA.



Rothschild, M.F. 2002. Approaches and limitations to measuring genetic diversity. EEC sponsored Conference on Swine Genetic Diversity, November 7, Cordoba, Spain.



Rothschild, M.F. 2002. Transferring Biotechnology to Swine Genetic Programs: From Lab to Pork. Spanish Swine Breeders Conference. November 5, Barcelona, Spain



Rothschild, M.F. and S. Newman. 2002. Intellectual property rights in animal breeding and genetics. CABI Press. 272 pages



Schwab, C. R., T. J. Baas, S. J. Moeller, and D. W. Newcom. 2003. Accuracy of prediction in the National Swine Improvement Federation (NSIF) Ultrasound Certification Program. Midwest ASAS Abstracts, p. 14.



Shi, X.W., Y.D. Zhang, and C.K. Tuggle. 2002. Linkage mapping of porcine STCH further refines the HSA3/21 breakpoint on pig chromosome 13. Anim. Genet. 33:395-396.



Sun, H.S., C.K. Tuggle, A. Goureau, C.J. Fitzsimmons, P. Chardon, P. Pinton, and M. Yerle. 2002. Precise mapping of breakpoints in conserved synteny between human chromosome 1 and pig chromosomes 4, 6, and 9. Anim. Gen. 33:91-96.



Sun, H.S., L. L. Anderson, T.-P. Yu, K.S. Kim, J. Klindt, and C. K. Tuggle. 2002. Neonatal Meishan pigs show POU1F1 genotype effects on plasma GH and PRL concentration. Anim. Reprod. Sci. 69:223-237.



Thomsen, H., J. C. M. Dekkers, and M. F. Rothschild. 2003. Detection and characterization of QTL for growth and meat quality traits in the Berkshire-Yorkshire cross. Swine Research Reports. Iowa State University.



Wang, J., J. Fulton, and J. Dekkers. 2003. Accuracy of detecting quantitative trait loci by selective DNA pooling. J. Anim. Sci. 81 (Suppl. 2):



Wang, J., K. Koehler, M. Soller, and J.C.M. Dekkers. 2003. Least squares interval mapping to detect QTL with selective DNA pooling. Plant and Animal Genome XI: 69.



MICHIGAN



Farber, C.R., N.E. Raney, D.L. Kuhlers, K. Nadarajah and C.W. Ernst. 2003. Mapping of porcine genetic markers generated by representational difference analysis. Anim. Biotech. 14:87-102.



Yao, J., P.M. Coussens, P. Saama, S. Suchyta and C.W. Ernst. 2002. Generation of expressed sequence tags from a normalized porcine skeletal muscle cDNA library. Anim. Biotech. 13:211-202.



Zhao, S-H., D. Nettleton, W. Liu, C.W. Fitzsimmons, C.W. Ernst N.E. Raney, and C.K. Tuggle. 2003. cDNA macroarray analysis of differential gene expression in porcine fetal and postnatal muscle. J. Anim. Sci. (Accepted)



Allison, C.P., R.O. Bates, A.M. Booren, R.C. Johnson and M.E. Doumit. 2003. Pork quality is not explained by activity of rate-limiting glycolytic enzymes. Meat Science 93:17-22.



Bates, R.O., D.B. Edwards and R.L. Korthals. 2003. Sow performance when housed in groups with electronic sow feeders or stalls. Livestock Production Science 79:29-35.



Bates, R.O., M.D. Hoge. B.E. Edwards and B. Straw. 2003. The influence of canine teeth clipping on nursing and nursery pig performance. Swine Health and Production 11(2):75-80.



Edwards, D.B., R.O. Bates and W.N. Osburn. 2003. Evaluation of Duroc- vs Pietrain-sired pigs for carcass and meat quality measures. J. Anim. Sci. 81: (Accepted).



Pagan, M. M.E. Davis, D.A. Stick, R.C.M. Simmen, N.E. Raney, R.J. Tempelman and C.W. Ernst. 2003. Evaluation of serum insulin-like growth factor binding proteins (IGFBP) in Angus cattle divergently selected for serum IGF-I concentration. Domest. Anim. Endocrinol. (Accepted).



NORTH CAROLINA



Holl, J. W. and O. W. Robison. 2003. Results from nine generations of selection for increased litter size in swine. J. Anim Sci. 81:624629, March 2003.



Blowe, C. D., E. J. Eisen, O. W. Robison, and J. P. Cassady. Characterization of a line of pigs selected for increased litter size for genes known to affect reproduction. J. Anim. Sci. 81(Suppl 1): 56, March 2003.



Walker, S., O. W. Robison, C. S. Whisnant, and J. P. Cassady. Effect of selection for testosterone production on testicular morphology and daily sperm production in pigs. J. Anim Sci.. 81(Suppl 1): 5, March 2003.



Cassady, J. P., K. A. Leymaster, and L. D. Young. Heterosis and recombination effects on pig reproductive traits. J. Anim Sci. 80(9):2286-2302, Sept. 2002



Cassady, J. P., K. A. Leymaster, and L. D. Young. Heterosis and recombination effects on pig growth and carcass traits. J. Anim Sci. 80(9):2303-2315, Sept. 2002.



OHIO



Stoller G. M., H. N. Zerby, S. J. Moeller, T. J. Baas, C. Johnson, and L. E. Watkins. 2003. The effect of feeding Ractopamine (Payleand) on muscle quality and sensory characteristics in three diverse genetic lines of swine. J. Anim. Sci. 81:1508-1516.



Moeller, S. J., T. J. Baas, T. D. Leeds, R. S. Emnett, and K. M. Irvin. 2003. Rendement Napole gene effects and a comparison of glycolytic potential and DNA genotyping for classification of Rendement Napole status in Hampshire-sired pigs. J. Anim. Sci. 81:402-410.



Isler, B. J., K. M. Irvin, S. M. Neal, S. J. Moeller, and M. E. Davis. 2002. Examination of the relationship between the estrogen receptor gene and reproductive traits in swine. J. Anim. Sci. 80:2334-2339.



NEBRASKA



Bertani G, Johnson RK, Pomp D (2003) Mapping of porcine ESTs putatively differentially expressed in anterior pituitary Animal Genetics 34:132-134.



Caetano A, RK Johnson, D Pomp (2003) Generation and Sequence Characterization of a Normalized cDNA Library from Swine Ovarian Follicles. Mammalian Genome 14:65-70.



Childs KD, DW Goad, MF Allan, D Pomp, C Krehbiel, RD Geisert, JB Morgan, JR Malayer (2002) Expression of the NAT1 translational repressor in intramuscular adipocytes of Angus X Hereford steers. Physiological Genomics 10:49-56.



Chiang, C. F., R. K. Johnson, and M. K. Nielsen. 2002. Maternal Behavior in Mice Selected for Large Litter Size. Appl. Anim. Behavior Sci. 79: 63-73.



Chiang, C. F., R. K. Johnson, and M. K. Nielsen. 2002. Selection for Maternal Behavior in Mice  Direct and Correlated Responses. Appl. Anim. Behaviour Sci. 79: 311-323.



Gladney C, G Bertani, MK Nielsen, D Pomp (2003) Evaluation of gene expression in pigs selected for enhanced reproduction. I: Ovarian Follicles. J Anim Sci (In Revision).



Leamy L, Pomp D, Eisen EJ, Cheverud J (2002) Pleiotropy of quantitative trait loci for organ weights and limb bone lengths in mice. Physiol. Genomics 10:21-29.



Mesa, H. t. J. Safranski, R. K. Johnson, and W. R. Lamberson. 2003. Correlated response in placental efficiency in swine selected for an index of components of litter size. J. Anim. Sci. 81: 74-79.



Risatti GR, D Pomp, RO Donis (2003) Patterns of cellular gene expression in cells infected with cytopathic or non-cytopathic bovine diarrhea virus. Animal Biotechnology (In Press).



Tuggle C, Green JA, Fitzsimmons C, Woods R, Prather RS, Malchenko S, Soares MB, Tack D, Robinson N, O‘Leary B, Scheetz T, Casavant T, Pomp D, Edeal JB, Zhang Y, Rothschild MF, Garwood K, Beavis W (2003) EST-Based Gene Discovery in Pig: Virtual Expression Patterns and Comparative Mapping to Human. Mammalian Genome (In Press).



Wesolowski S, Allan MF, Nielsen MK, Pomp D (2003) Evaluation of hypothalamic gene expression in mice selected for heat loss. Physiological Genomics 13:129-137.



Williams RW, Broman KW, Cheverud JM, Churchill GA, Hitzemann RW, Hunter Kw, Muntz

JD, Pomp P, Reeves RH, Schalkwyk LC, Threadgill DW (2002) A collaborative cross for high

precision complex trait analysis. www.complextrait.org/Workshop1.pdf



Ziemba EA, R. K. Johnson, and g. E. Duhamel. 2002. Identification of Brachyspira pilosicoli attachment phenotypes among purebred and crossbred pigs as determined by epithelial cell brush border adhesion. CRWAD, St. Louis, MO.



Ziemba EA, E. M. Berberov, C. J. Stryker, R. Zhang, R. K. Johnson, and G. E. Duhamel. Attachment of Brachyspira pilosicoli to Pig Intestinal Brush Borders: Identification of Three Pig Phenotypes. CRWAD. Nov 12-13, St. Louis, MO.



OKLAHOMA



C. R. Krehbiel, S. R. Rust, G. Zhang, and S. E. Gilliland. 2003. Bacterial Direct-Fed Microbials in Ruminant Diets: Performance Response and Mode of Action. J. Anim. Sci. (In press).



USDA, ARS, BARC



Lunney, J.K. 2003. In Search of Disease-Resistant Pigs. National Hog Farmer, Apr 15, 2003, pp.30-34.



Martens G W, Lunney J K, Baker J E, Smith D M. 2003. Rapid Assignment of Swine Leukocyte Antigen (SLA) Haplotypes in Pedigreed Herds using a Polymerase Chain Reaction Based Assay. Immunogenetics. In Press.



Lunney JK, Fossum C, Alm GV, Steinbach F, Wattrang E. 2002. Veterinary immunology: opportunities and challenges. Trends Immunol. 23: 4-6.



Solano-Aguilar, G.I., Zarlenga, D., Beshah, E., Vengroski, K, Gasbarre, L., Junker, D., Cochran, M., Weston, C., Valencia, D., Chiang, C., Dawson H, Urban J, and Lunney, J.K. 2002. Limited effect of recombinant porcine Interleukin-12 on porcine lymphocytes due to a low expression of IL-122 receptor. Vet. Immunol. Immunopathol. 89: 133-148.

10/02/2004

Publications: * Indicates joint publication of institutions within NC1004 project

INDIANA
Bidwell, C.A., M. Spurlock, and D. Moody. 2003. Serial analysis of gene expression of pig adipose and muscle tissue. Plant and Animal Genomes XI Conference, San Diego, CA. www.intl-pag.org/11/abstracts/P01_P69_XI.html.

IOWA
*Baas, T. J., R. N. Goodwin, L. L. Christian, R. K. Johnson, O. W. Robison, J. W. Mabry, K. Clark, M. Tokach, S. Henry, and P. J. Berger. 2003. Design and standards for genetic evaluation of swine seedstock populations. J. Anim Sci. 81:2409-2418.

Chen, P., T. J. Baas, J. C. M. Dekkers, K. J. Koehler, and J. W. Mabry. 2003. Evaluation of strategies for selection for lean growth rate in pigs. J. Anim Sci. 81:1150-1157.

Chen, P., T. J. Baas, J. W. Mabry and K. J. Koehler. 2003. Genetic correlations between lean growth and litter traits in U.S. Yorkshire, Duroc, Hampshire and Landrace pigs. J. Anim. Sci. J. Anim. Sci. 81:1700-1705.

Chen, P., T. J. Baas, J. W. Mabry, K. J. Koehler, and J. C. M. Dekkers. 2003. Genetic parameters and trends for litter traits in U.S. Yorkshire, Duroc, Hampshire, and Landrace pigs. J. Anim Sci. 81:46-53.

Dekkers, J.C.M. 2003. Commercial application of marker-assisted selection: strategies and lessons. J. Anim. Sci. 81 (Suppl. 1): 5

Dekkers, J.C.M. 2003. Commercial application of marker-assisted selection: strategies and lessons. Eur. Assoc. Anim. Prod.

Lampe, J. F., T. J. Baas and J. W. Mabry. 2003. Comparison of grain sources (barley, white corn, yellow corn) for swine diets and their effect on meat and eating quality traits. J. Anim. Sci. 81: 55 (Suppl. 2).

Lampe, J. F., T. J. Baas and J. W. Mabry. 2003. Comparison of grain sources (barley, white corn, yellow corn) for swine diets and their effect on fatty acid composition and fat quality. J. Anim. Sci. 81: 76 (Suppl. 1).

Liviu R. Totir, R.L. Fernando, J.C.M. Dekkers, S.A. Fernandez, and B. Guldbrandtsen. 2003. A comparison of alternative methods to compute conditional genotype probabilities for genetic evaluation with finite locus models. Genet. Sel. Evol. 35:1-20

Mabry, J. W. Closed herd production systems: Genetic systems and genetic cost of production. Proceedings of the 2003 NPB Pork Academy, June 4, 2003, Des Moines, IA.

N.-T. Nguyen, K.-S. Kim, H. Thomsen, J. Helm and M. F. Rothschild 2003. Investigation of candidate gene for growth and fatness QTL on the pig chromosome 7. Proceedings Plant & Animal Genome XI meeting, January 11-15 San Diego, CA.

Newcom, D. W., and T. J. Baas. 2003. Comparison of two models to estimate breeding values for intramuscular fat percentage in Duroc pigs. J. Anim Sci 82 (Suppl 1).

Rothschild, M.F. 2003. Advances in pig genomics and functional gene discovery. Comp. Funct. Genom. 4:266-277.

Rothschild, M.F. 2003. Approaches and Challenges in Measuring Genetic Diversity in Pigs. Archivos de Zootecnia 52:129-135

Spike, P.L., R. R. Benson, R. L. Fernando, J. C. M. Dekkers, P. J. Berger, and B. R. Skaar. 2003. A simulation program using finite loci with infinite possibilities, FLIP. J. Anim. Sci. 81 (Suppl. 1): 113

*Stoller, G. M., H. N. Zerby, S. J. Moeller, T. J. Baas, C. Johnson, and L. E. Watkins. 2003. The effect of feeding ractopamine (Paylean) on muscle quality and sensory characteristics in three diverse genetic lines of swine. J. Anim Sci. 81:1508-1516.

Totir, L.R., R. L. Fernando, and J.C.M. Dekkers. 2003. Response to selection by marker assisted BLUP with use of approximate gametic variance covariance matrices. J. Anim. Sci. 81 (Suppl. 1): 113

*Tuggle, C.K., J. A. Green, C. Fitzsimmons, R. Woods, R. S. Prather, S. Malchenko, M. B. Soares, D. Tack, N. Robinson, B. O'Leary, T. Scheetz, T. Casavant, D. Pomp, J. B. Edeal, Y. Zhang, M. F. Rothschild, K. Garwood, W. Beavis .2003. EST-Based Gene Discovery in Pig: Virtual Expression Patterns and Comparative Mapping to Human, Mammal. Genome 14:565-579

Zhao, H., M. F. Rothschild, R. L. Fernando, J. C.M. Dekkers 2003. Tests of candidate genes in QTL mapping resource populations. Mammal. Genome 14:472-482.

*Zhao, S.-H., D. Nettleton, W. Liu, C. Fitzsimmons, C.W. Ernst, N.E. Raney, and C.K. Tuggle. 2003. Complementary DNA macroarray analyses of differential gene expression in porcine fetal and postnatal muscle. J. Anim. Sci. 81:2179-2188.

MICHIGAN
*Ernst, C.W., N.E. Raney, V.D. Rilington, G.A. Rohrer, J.A. Brouillette and P.J. Venta. 2004. Mapping of the FES and FURIN genes to porcine chromosome 7. Anim. Genet. In Press.

Farber, C.R., N.E. Raney, V.D. Rilington, P.J. Venta and C.W. Ernst. 2004. Comparative mapping of genes flanking the human chromosome 12 evolutionary breakpoint in the pig. Cytogenet. Genome Res. In Press.

Wesolowski, S.R., N.E. Raney and C.W. Ernst. 2004. Developmental changes in the fetal pig transcriptome. Physiol. Genomics. In Press.

*Zhao, S-H., D. Nettleton, W. Liu, C.W. Fitzsimmons, C.W. Ernst, N.E. Raney and C.K. Tuggle. 2003. Complementary DNA macroarray analysis of differential gene expression in porcine fetal and postnatal muscle. J. Anim. Sci. 81:2179-2188.


NEBRASKA
Bertani G, Gladney C, Johnson RK, Pomp D (2004) Evaluation of gene expression in pigs selected for enhanced reproduction. II: Anterior Pituitary. J Anim Sci (In Press).

Gladney C, G Bertani, MK Nielsen, D Pomp (2004) Evaluation of gene expression in pigs selected for enhanced reproduction. I: Ovarian Follicles. J Anim Sci (In Press).

*Rocha J, Eisen EJ, Van Vleck DL, Pomp D (2004) A large sample QTL study in mice. I: Growth. Mammalian Genome (In Press)

*Rocha J, Eisen EJ, Van Vleck DL, Pomp D (2004) A large sample QTL study in mice. II: Body Composition. Mammalian Genome (In Press)

Pomp D, Allan MF, Wesolowski S. Quantitative Genomics: Exploring the genetic architecture of complex trait predisposition. J Anim Sci (In Press).


NORTH CAROLINA
Walker, S. E., O.W. Robison, C.S. Whisnant, and J.P. Cassady. Effect of selection for testosterone production on testicular morphology and daily sperm production in pigs. J. Anim Sci.. 81(Suppl. 1), 23 Jun 2003

Walker, S. E., O.W. Robison, C.S. Whisnant, and J.P. Cassady. Effect of selection for testosterone production on testicular morphology. (Submitted)

OKLAHOMA
Patil, A., Y. Sang, K. Rune, F. Blecha, J.E. Minton, and G. Zhang. 2003. Porcine Innate Immunity: Distinct Tissue Expression and Transcriptional Regulation Patterns of Porcine Beta-Defensin-1 and 2. Proceedings of the 84th Annual Meeting of the Conference of Research Workers in Animal Diseases (CRWAD), Chicago, IL.

Xiao, Y., S. Eicher, H.-W. Cheng, J.-F. Cheng, D. Skinner-Noble, and G. Zhang. 2003. Identification and Characterization of a Beta-Defensin Gene Cluster in the Chicken. Proceedings of the 84th Annual Meeting of the Conference of Research Workers in Animal Diseases (CRWAD), Chicago, IL.

Zhang, G. 2003. Genome-wide analysis of rat _- and _-defensin gene loci: evidence for the existence of four syntenic defensin gene clusters. 2004 Experimental Biology Meeting abstracts. FASEB J. (in press)

USDA, ARS, BARC
Martens G W, Lunney J K, Baker J E, Smith D M. 2003. Rapid Assignment of Swine Leukocyte Antigen (SLA) Haplotypes in Pedigreed Herds using a Polymerase Chain Reaction Based Assay. Immunogenetics. 55: 395-401.

Dawson HD, Beshah E, Nishii S, Solano-Aguilar G, Morimoto M, Zhao A, Madden KB, Ledbetter TK, Dubey JP, Shea-Donohue T, Lunney JK, Urban, JF Jr. Localized multi-gene expression patterns support an evolving Th1/Th2-like paradigm in response to infections with Toxoplasma gondii and Ascaris suum in pigs. Submitted.

Lunney, J.K. 2003. Are there immune gene alleles that determine whether a pig will be healthy? Genetics of Pig Health Symposium, Des Moines, IA.

Bannerman, D., Paape, M.J., Lunney, J.K. 2004.Immunity: Innate. In Encyclopedia of Animal Science; Pond, W.G., Bell, A.W. Eds.; Marcel Dekker, Inc., New York.

Lunney, J.K., Paape, M.J., Bannerman, D. 2004. Immunity: Acquired. In Encyclopedia of Animal Science; Pond, W.G., Bell, A.W. Eds.; Marcel Dekker, Inc., New York.

Royaee AR. Zuckermann FA, Husmann R, Calzada-Nova G, Schnitzlein W, Lunney JK, T cell cytokine response and gene expression profile of porcine lymphoid cells in response to vaccination with PRRS virus. Proceedings Conf. of Research Workers in Animal Disease 2003.

*Smith DM, Martens GW, Lunney JK, Ando A, Lee J-H, Ho C-S, Schook L, Renard C, Chardon P. 2004. Nomenclature for Factors of the SLA Class I System, 2004. Tissue Antigens. Submitted.

Dawson HD, Royaee AR, Nishii S, Kuhar D, Schnitzlein WM, Zuckermann F, Urban JF, Lunney JK. 2004. Identification of Key Immune Mediators Regulating T helper 1 Responses in Swine. Vet. Immunol. Immunopathol. Submitted.

Harry Dawson, Sandra Nishi, Ethiopia Beshah, Gloria Solano-Aguilar, Dante Zarlenga, Joseph F. Urban, Joan Lunney. 2003. Use of real-time assays of immune gene expression to assess the genetic basis of disease resistance. http://www.intl-pag.org/11/abstracts/W52_W330_XI.html

Nishi, S., Dawson, H., Dubey, J.P., Urban, J.F., Lunney, J. 2003. Immune responses controlling Toxoplasma gondii infection in pigs. Proceedings of the American Association of Veterinary Parasitologists, 2003. v.48. Abstract. p.52.

10/17/2005

* Indicates joint publications of stations within NC1004 project

IOWA

*Baas, T. J., K. J. Stalder, J. W. Mabry, and M. T. See. 2004. Effect of off test backfat, loin muscle area, and days to 114 kg on the genetic merit of Yorkshire females for reproductive traits. 15th International Congress on Animal Reproduction, Porto Seguro, Brazil.

*Cassady, J. P., O. W. Robison, R. K. Johnson, J. W. Mabry, L. L. Christian, M. D. Tokach, R. K. Miller, and R. N. Goodwin. 2004. National Pork Producers Council Maternal Line Genetic Evaluation: A comparison of growth and carcass traits in terminal progeny. J. Anim. Sci. 82:3482-3485.

Ciobanu, D.C., J.W.M. Bastiaansen, S.M. Lonergan, H. Thomsen, J.C.M. Dekkers, G.S. Plastow, and M.F. Rothschild. 2004. New alleles in calpastatin gene are associated with meat quality traits in pigs. J. Animal Sci. 82:2829-2839.

Ciobanu, D.C., Lonergan, S.M., Bastiaansen, J.W.M.,Mileham, Miculinich,, Schultz-Kaster, C., Sosnicki, A.A., Plastow , G.S. and M.F. Rothschild. 2004. Association of new Calpastatin alleles with meat quality traits in commercial pigs. 50th Int. Congress of Meat Science and Technology, Helsinki, Finland.

Dekkers, J.C.M. 2004. Commercial application of marker- and gene-assisted selection in livestock: strategies and lessons. J. Anim. Sci. 82: E313-328E

Dekkers, J.C.M., and R. Chakraborty. 2004. Optimizing purebred selection for crossbred performance using QTL. Genet. Sel. Evol. 36: 297-324.

Fernando, R.L., B. R. Southey, J.C.M. Dekkers, M.F. Rothschild, and M. Soller. 2004. Controlling the proportion of false positives (PFP) in a multiple test situation. Genetics 166: 611-619.

Gaboreanu, A.M., L. Grapes, A. M. Ramos, J.-J. Kim and M. F. Rothschild. 2004. Characterization of an X-chromosome PCR-RFLP marker associated with fat deposition and growth in the pig. Animal Genetics 35: 401-403.

Grapes, L., J.C.M. Dekkers, M.F. Rothschild, and R.L. Fernando. 2004. Comparing linkage disequilibrium-based methods for fine mapping quantitative trait loci. Genetics 166: 1561-1570.

Grapes, L., M. Z. Firat, J. C. M. Dekkers, M. F. Rothschild, and R. L. Fernando. 2004. Optimal haplotype structure for linkage disequilibrium-based fine mapping of quantitative trait loci. American Association of Animal Science Midwest Region, Mar 15-17, Des Moines, IA

Grapes, L., S. Rudd, R. L. Fernando, and M. F. Rothschild. 2004. In silico SNP identification from porcine EST sequences and comparative analysis with human SNP density. Plant and Animal Genome XII, Jan 10-14, San Diego, CA

Grindflek, E, N Hoen, H Sundvold, MF Rothschild, G Plastow, and S Lien. 2004. Investigation of a Peroxisome Proliferator Activated Receptor gamma (PPARG) haplotype effect on meat quality and carcass traits in pigs. Anim. Genet 35:238-241.

Houser, T. A., J. G. Sebranek, B. J. Thacker, T. J. Baas, D. Nilubol, E. L. Thacker, and F. Kruse. 2004. Effectiveness of transdermal, needle-free injections for reducing pork carcass defects. Meat Science 68:329-332.

Hu, Z-L, K. Glenn, A. M. Ramos, C. J. Otieno, and M. F. Rothschild. 2004. Expeditor: A Pipeline for Designing Pig Primers Using Human Gene Structure and Pig EST Information. Plant and Animal Genome XII, Jan 10-14, San Diego, CA

*Johnson, R. K., E. P. Berg, R. Goodwin, J. W. Mabry, R. K. Miller, O. W. Robison, H. Sellers and M. D. Tokach. 2004. Evaluation of procedures to predict fat-free lean in swine carcasses. J. Anim. Sci. 82:2428-2441.

Kim, J.-J. and J. C. M. Dekkers. 2004. A combined line-cross and halfsib model to detect and characterize QTL in an F2 outbred cross population. American Society of Animal Science Annual meeting (Abstract). http://www.fass.org/2004/abstracts/414.PDF

Kim, K.S., J. J. Kim, J. C. M. Dekkers, and M. F. Rothschild. 2004. Polar overdominant inheritance of a DLK1 polymorphism is associated with growth and fatness in pigs. Mammalian Genome 15:552-559.

Kim, K.S., J.J. Kim, J.C.M. Dekkers, and M.F. Rothschild. 2004. Polar overdominance imprinting is associated with growth and fat deposition in pigs. PAG XII p240

Kim, K.S., J.M. Reecy, W.H. Hsu, and L.L. Anderson. 2004. Functional and phylogenetic analyses of a melanocortin-4 receptor mutation in domestic pigs. Domestic Animal Endocrinology 26: 75-86.

Martin, B. D., T. J. Baas, C. Schwab, D. W. Newcom, J. F. Lampe, and K. J. Stalder. 2004. Comparison of deposition rates for loin muscle area, backfat, and intramuscular fat percentage among breeds in the 2003 National Barrow Show Sire Progeny Test. J. Anim. Sci. 82 (Suppl. 1):455.

*Moeller, S. J., R. N. Goodwin, R. K. Johnson, J. W. Mabry, T. J. Baas, and O. W. Robison. 2004. The National Pork Producers Council Maternal Line National Genetic Evaluation Program: A comparison of six maternal genetic lines for female productivity measures over four parities. J. Anim Sci. 82:41-53.

*Moller, M., F. Berg, J. Riquet, D. Pomp, A. Archibald, S. Anderson, K. Feve, Y. Zhang, M.F. Rothschild, D. Milan, L. Andersson and C.K. Tuggle. 2004. High-resolution comparative mapping across pig chromosome 4 (SSC4), emphasizing the FAT1 region. Mammalian Genome 15: 717-31.

Mote, B. E., J. D. Loy, and M. F. Rothschild. 2004. Identification of SNPs in the insulin-like growth factor gene family and subsequent mapping of IGF2R and IGFBP1 in pigs. Plant and Animal Genome XII, Jan 10-14, San Diego, CA

Newcom, D. W., J. L. Burkett, T. J. Baas, C. R. Schwab, S. J. Moeller, and K. J. Stalder. 2004. Effect of technician, machine, and animal body composition on accuracy of ultrasonic measures of backfat and loin muscle area in swine. J. Anim. Sci. 82 (Suppl. 2):46.

Newcom, D. W., K. J. Stalder, T. J. Baas, R. N. Goodwin, F. C. Parrish, and B. R. Wiegand. 2004. Breed differences and genetic parameters of myoglobin concentration in porcine longissimus muscle. J. Anim Sci. 82:2264-2268.

Newcom, D. W., T. J. Baas, and K. J. Stalder. 2004. Relationship between backfat depth and its individual layers and intramuscular fat percentage in swine. J. Anim. Sci. 82 (Suppl. 2):39.

Rothschild, M.F. 2004. Porcine genomics delivers new tools and results: This little piggy did more than just go to market. Genetical Research 83:1-6.

Rothschild, M.F. 2004. DNA advances offer big payoffs. Pig Progress Magazine. 20:1-3.

Rothschild, M.F. J. P. Bidanel and D.C. Ciobanu. 2004. Genome Analysis of QTL for Muscle Tissue Development and Meat Quality. In: Muscle Development of Livestock Animals. Physiology, Genetics and Muscle Quality. Eds: M.F. W. te Pas, H.P. Haagsman and M.E. Everts. CABI Publishing pgs 247-266.

Rothschild, M.F., G.S. Plastow and S. Newman. 2004. Patenting in animal breeding and genetics. In: WAAP Book of the Year 2003, Eds: A. Rosati, A. Tewolde and C. Mosconi. Pgs 269-280.

Schwab, C. R., T. J. Baas, D. W. Newcom, and K. J. Stalder. 2004. An evaluation of performance and carcass characteristics between pigs sired by boars from two different time periods. J. Anim. Sci. 82 (Suppl. 1): 453.

Schwab, C. R., T. J. Baas, D. W. Newcom, and K. J. Stalder. 2004. An evaluation of meat and eating quality traits between pigs sired by boars from two different time periods. J. Anim. Sci. 82 (Suppl. 1): 454.

Schwab, C. R., T. J. Baas, D. W. Newcom, and K. J. Stalder. 2004. Comparison of growth patterns for loin muscle area, backfat, and intramuscular fat percentage between pigs sired by boars from two different time periods. J. Anim. Sci. 82 (Suppl. 2): 9.

Serenius, T., and K. J. Stalder. 2004. Genetics of length of productive life and lifetime prolificacy in the Finnish Landrace and Large White pig populations. J. Anim. Sci. 82:3111-3117.

Stalder, K. J., M. Knauer, T. J. Baas, M. F. Rothschild, and J. W. Mabry. 2004. Sow Longevity. Pig News and Information. 25:53N-74N.

Thomsen, H., J. C. M. Dekkers, H. K. Lee, and M. F. Rothschild. 2004. Characterization of quantitative trait loci for growth and meat quality in a cross between commercial breeds of swine J. Anim. Sci. 82:2213-2228.

Totir, L.R., R.L. Fernando, J.C.M. Dekkers, and S.A. Fernandez. 2004. A study of the minimum number of loci required for genetic evaluation using a finite locus model. Genet. Sel. Evol. 36: 395-414

Totir, L.R., R.L. Fernando, J.C.M. Dekkers, S.A. Fernandez, and B. Guldbrandtsen. 2004. Effect of using approximate gametic variance covariance matrices on marker assisted selection by BLUP. Genet. Sel. Evol. 36:29-48.

Tuggle, C.K., and Midwest Consortium. 2004. Finding the genes expressed in female reproductive tissues in pigs. Bulletin AS 650, January, 2004, Animal Industry Report 2004, Iowa State University, Ames, IA ASL-R1950.

Tuggle, C.K., X.W. Shi, L. Marklund, A. Stumbaugh, T.J. Stabel, M.A Mellencamp, L. Galina-Pantoja, and J. Bastiaansen 2004. Association of bacterial infection traits with genetic variation at candidate genes for porcine disease resistance. Bulletin AS 650, Animal Industry Report 2004, Iowa State University, Ames, IA ASL-R1952.

*Tuggle, C.K., Y. Zhang, M.F. Rothschild, M.Moller, F. Berg, L. Anderson, J. Riquet, D. Milan, D. Pomp, A. Archibald, and S. Anderson. 2004. A detailed gene map of pig chromosome 4, where the first quantitative trait locus in livestock was mapped. Bulletin AS 650, Animal Industry Report 2004, Iowa State University, Ames, IA ASL-R1951.

Villanueva, B., J.C.M. Dekkers, J. A. Woolliams, and P. Settar. 2004. Maximizing genetic gain over multiple generations with quantitative trait locus selection and control of inbreeding. J. Anim Sci. 82: 1305-1314.

Wilke, V. L., B. P. Kinghorn, M. G. Conzemius, and M. F. Rothschild. 2004. Prediction of inheritance for cranial cruciate ligament disease in the Newfoundland dog. Abstract to be presented at the 31st Annual Conference of the Veterinary Orthopedic Society.
Wilke, V. L., B. P. Kinghorn, M. G. Conzemius, and M. F. Rothschild. 2004. Prediction of inheritance for cranial cruciate ligament disease in the Newfoundland dog. Presented at the 2004 ASAS/ADSA Midwestern Meeting, Des Moines, IA.

Zhao, H., D. Nettleton, M. Soller, and J. C. M. Dekkers. 2004. Linkage disequilibrium measures between markers as predictors of linkage disequilibrium between markers and QTL. J. Anim Sci. 82 (Suppl. 2) p.9.

Zhao, H., J.-J. Kim , M. Perez-Enciso, and J. C. M. Dekkers. 2004. Detection of quantitative trait loci segregation within pure breeds in a Berkshire x Yorkshire F2 population.American Society of Animal Science Annual meeting (Abstract). http://www.fass.org/2004/abstracts/452.PDF

Zhao, S.-H. A. Erickson, and C.K. Tuggle. 2004. Physical and Linkage mapping of lymphocyte antigen 86 (Ly86) gene to porcine chromosome 7. Anim. Genet. 35:164.

Zhao, S.-H. and C.K. Tuggle. 2004. Linkage mapping and expression analyses during early gestation in the pig of a novel gene, PLacentally Expressed Transcript 1 (PLET1). Anim. Genet. 35:72-74.

Zhao, S.-H., D. G. Simmons, J.C. Cross, T.E. Scheetz, T.L. Casavant, M. B. Soares, and C.K. Tuggle. 2004. PLET1, a highly expressed and processed novel gene in pig and mouse placenta is transcribed but poorly spliced in human. Genomics 84:114-125.



MICHIGAN

Ernst, C.W., N.E. Raney, V.D. Rilington, G.A. Rohrer, J.A. Brouillette and P.J. Venta. 2004. Mapping of the FES and FURIN genes to porcine chromosome 7. Anim. Genet. 35:142-143.

Farber, C.R., N.E. Raney, V.D. Rilington, P.J. Venta and C.W. Ernst. 2003. Comparative mapping of genes flanking the human chromosome 12 evolutionary breakpoint in the pig. Cytogenet. Genome Res. 102:139-144.

Wesolowski, S.R., N.E. Raney and C.W. Ernst. 2004. Developmental changes in the fetal pig transcriptome. Physiol. Genomics. 16:268-274.



NEBRASKA

*T. J. Baas, R. N. Goodwin, L. L. Christian, R. K. Johnson, O. W. Robison, J. W. Mabry, K. Clark, M. Tokach, S. Henry and P. J. Berger. 2003. Design and standards for genetic evaluation of swine seedstock populations . J. Anim. Sci. 2003. 81:2409-2418.

*J. P. Cassady, O. W. Robison, R. K. Johnson, J. W. Mabry, L. L. Christian, M. D. Tokach, R. K. Miller and R. N. Goodwin. 2004. National Pork Producers Council Maternal Line Genetic Evaluation: A comparison of growth and carcass traits in terminal progeny. J. Anim. Sci. 2004. 82:3482-3485.

*J. W. Holl, J. P. Cassady, D. Pomp and R. K. Johnson. 2004. A genome scan for quantitative trait loci and imprinted regions affecting reproduction in pigs. J. Anim. Sci. 2004. 82:3421-3429.

*R. K. Johnson, E. P. Berg, R. Goodwin, J. W. Mabry, R. K. Miller, O. W. Robison, H. Sellers and M. D. Tokach. 2004. Evaluation of procedures to predict fat-free lean in swine carcasses. J. Anim. Sci. 2004. 82:2428-2441.

D. B. Petry and R. K. Johnson. 2004. Responses to 19 generations of litter size selection in the Nebraska Index line. I. Reproductive responses estimated in pure line and crossbred litters. J. Anim. Sci. 2004. 82:1000-1006.

D. B. Petry, J. W. Holl and R. K. Johnson. 2004. Responses to 19 generations of litter size selection in the NE Index line. II. Growth and carcass responses estimated in pure line and crossbred litters. J. Anim. Sci. 2004. 82:1895-1902.

*S. J. Moeller, R. N. Goodwin, R. K. Johnson, J. W. Mabry, T. J. Baas and O. W. Robison. 2004. The National Pork Producers Council Maternal Line National Genetic Evaluation Program: A comparison of six maternal genetic lines for female productivity measures over four parities. J. Anim. Sci. 2004. 82:41-53.

G. R. Bertani, C. D. Gladney, R. K. Johnson and D. Pomp. 2004. Evaluation of gene expression in pigs selected for enhanced reproduction using differential display PCR: II. Anterior pituitary. J. Anim. Sci. 2004. 82:32-40.

C. D. Gladney, G. R. Bertani, R. K. Johnson and D. Pomp. 2004. Evaluation of gene expression in pigs selected for enhanced reproduction using differential display PCR and human microarrays: I. Ovarian follicles. J. Anim. Sci. 2004. 82:17-31.

Petry, D. B., J. Holl, J. Weber, A. Doster, F. Osorio, and R. Johnson. 2004. Different biological responses of pigs of two genetic populations to PRRSV challenge suggests underlying genetic variation in susceptibility/resistance to PRRSV. NE Swine Report, EC 04-219 A: 24-28.

Holl, J. and R. Johnson. 2004. Major genes affect reproduction and early growth. 2004. NE Swine Report, EC 04-219 A: 28-31.

*J. Holl, J. P. Cassady, D. Pomp , and R. K. Johnson. 2004. Identification of quantitative trait loci affecting reproduction and early growth in pigs. J Anim. Sci. Vol. 82, Suppl. 1: 452.

D. B. Petry, J. W. Holl, F. A. Osario, A. R. Doster, J. S. Weber, and R. K. Johnson. 2004. Biological responses of pigs from two populations to PRRSV challenge. Journal of Animal Science Vol. 82, Suppl. 2: 39.

*J. W. Holl, J. P., Cassady, and R. K. Johnson. 2004. Identification of quantitative trait loci affecting birth and weaning weights in pigs. J. Anim. Sci. Vol. 81, Suppl. 1: 195.



NORTH CAROLINA

*Cassady, J. P., O. W. Robison, R. K. Johnson, J. W. Mabry, L. L. Christian, M. D. Tokach, R. K. Miller, R. N. Goodwin. National Pork Producers Council Maternal Line Genetic Evaluation: A comparison of growth and carcass traits in terminal progeny. Journal of Animal Science. 82(12): 3482-5, 01 Dec 2004.

*Holl, J. W., J. P. Cassady, D. Pomp, R. K. Johnson. A genome scan for quantitative trait loci and imprinted regions affecting reproduction in pigs. Journal of Animal Science. 82(12): 3421-9, 01 Dec 2004.

House, R.L., J.P. Cassady, E.J. Eisen, T.E. Eling, and J. Odle. Functional genomic characterization of polygenic obese mice fed t10, c12 conjugated linoleic acid (CLA). FASEB J. 18(4&5), 2004.

*Van Vleck, L. D., J. P. Cassady. Unexpected estimates of variance components with a true model containing genetic competition effects. Journal of Animal Science. 2005 Accepted.

Walker, S. E., O.W. Robison, C.S. Whisnant, and J.P. Cassady. Effect of divergent selection for testosterone production on testicular morphology and daily sperm production in boars. Journal of Animal Science. 82(8): 2259-63, 01 Aug 2004.

Bender, J.M., J.P. Cassady. 2004. Growth and carcass composition in lines divergently selected for testosterone production and their crossbred progeny. Journal of Animal Science Supplement 1

*Van Vleck, L.D., J.P. Cassady. 2004. Random models with direct and competition genetic effects. Proceedings, 2004 Conference on Statistics in Agriculture, Manhattan, KS

*Van Vleck, L.D., J.P. Cassady. 2004. Unexpected estimates of variance components with a true model containing genetic competition effects. Journal of Animal Science Supplement 1

*Cassady, J.P., L.D. Van Vleck. 2004. Estimation of (co) variance components due to genetic competition effects in pigs. Journal of Animal Science Supplement 1

*Holl, J.W., J.P. Cassady, R.K. Johnson. 2004. Identification of quantitative trait loci affecting birth and weaning weights in pigs. Journal of Animal Science Supplement 1

*Holl, J.W., J.P. Cassady, D. Pomp, R.K. Johnson. 2004. Identification of quantitative trait loci affecting reproduction and early growth in pigs. Journal of Animal Science Supplement 1

Blowe, C.D., E.J. Eisen, O.W. Robison, and J.P. Cassady. 2004. Characterization of a line of pigs selected for increased litter size for two RFLPs identified in follistatin C. D. Blowe, E. J. Eisen, O. W. Robison, and J. P. Cassady. Journal of Animal Science Supplement 1



OHIO

*Moeller, S. J., R. N. Goodwin, R. K. Johnson, J. W. Mabry, T. J. Baas, O. W. Robison. 2004. The National Pork Producers Council Maternal Line National Genetic Evaluation Program: A comparison of six maternal genetic lines for female productivity measures over four parities. J. Anim. Sci. 82: 41-53



OKLAHOMA

Vonnahme,K.A., Fernando,S.C., Ross,J.W., Ashworth,M.D., DeSilva,U., Malayer,J.R., and Geisert,R.D. (2004). Porcine endometrial expression of kininogen, factor XII, and plasma kallikrein in cyclic and pregnant gilts. Biology of Reproduction 70, 132-138



USDA-BARC

Martens GW, Lunney JK, Baker JE, Smith DM. 2003. Rapid Assignment of Swine Leukocyte Antigen (SLA) Haplotypes in Pedigreed Herds using a Polymerase Chain Reaction Based Assay. Immunogenetics. 55: 395-401.

Dawson HD, Beshah E, Nishi S, Solano-Aguilar G, Morimoto M, Zhao A, Madden KB, Ledbetter TK, Dubey JP, Shea-Donohue T, Lunney JK, Urban, JF Jr. Localized multi-gene expression patterns support an evolving Th1/Th2-like paradigm in response to infections with Toxoplasma gondii and Ascaris suum in pigs. Infection and Immunity. In Press.

*Smith DM, Martens GW, Lunney JK, Ando A, Lee J-H, Ho C-S, Schook L, Renard C, Chardon P. 2004. Nomenclature for Factors of the SLA Class I System, 2004. Tissue Antigens. In Press.

Dawson HD, Royaee AR, Nishi S, Kuhar D, Schnitzlein WM, Zuckermann F, Urban JF, Lunney JK. 2004. Identification of Key Immune Mediators Regulating T helper 1 Responses in Swine. Vet. Immunol. Immunopathol. 100: 105-111.

Royaee AR, Husmann R, Dawson HD, Calzada-Nova G, Schnitzlein WM, Zuckermann F, Lunney JK. 2004. Deciphering the involvement of innate immune factors in the development of the host responses to PRRSV vaccination. Vet. Immunol. Immunopathol. 102: 199-216.

Meier WA, Husmann RJ, Calzada-Nova G, Schnitzlein WM, Lunney JK, Zuckermann FA. 2004. In vivo modulation of the PRRS virus vaccine-induced immune responses of swine toward a Th1 phenotype. Vet. Immunol. Immunopathol. 102: 299-314.

Galina-Pantoja L, Solano-Aguilar GI, Mellencamp MA, Bastiaansen J, Lunney JK. 2004. Relationship between immune cells and pig growth on a commercial farm. Proc. 18th IPVS Congress, Hamburg, Germany, 2004, Vol. I. p.381.

Bannerman D, Paape MJ, Lunney JK. 2004. Immunity: Innate. In Encyclopedia of Animal Science; Pond, W.G., Bell, A.W. Eds.; Marcel Dekker, Inc., New York. p.552-554.

Lunney JK, Paape MJ, Bannerman D. 2004. Immunity: Acquired. In Encyclopedia of Animal Science; Pond, W.G., Bell, A.W. Eds.; Marcel Dekker, Inc., New York. p.548-551.

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