NE2439: Improving the health span of aging adults through diet and physical activity

(Multistate Research Project)

Status: Active

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SAES-422 Reports

10/31/2025

Published Journal Articles (19 TOTAL)



  1. Yang B*, Manifold B*, Han W*, DeSousa C, Zhu W, Streets A*, Titov DV*. SRS microscopy identifies inhibition of vitellogenesis as a mediator of lifespan extension by caloric restriction in C. elegans. bioRxiv 2025.01.31.636008.

  2. Monroe-Lord, L., Ardakani, A., Schweitzer, A.,et al. Demographic Determinants of Food Insecurity in Older Adults During the COVID-19 Pandemic. Nutrients 2025, 17(18), 2934; https://doi.org/10.3390/nu17182934

  3. Richards, M., Russo, Y., Duarte, S., et al., Food Security, Mental Health Status and Prostate Cancer in US Men: 2023 NHIS Data. Journal of Food Security, 2025;13(3), 99-105. DOI: 10.12691/jfs-13-3-3

  4. Kim, H., Eubank, J.M., Orazem, J., et al. The impact of a sense of belonging on the health-related quality of life among the elderly in New York City. American Journal of Public Health Research, 2025; 13(1), 20-37. DOI: 10.12691/ajphr-13-1-4

  5. Oberlin, D.J., Eubank, J.M., Kim, H., et al. Descriptive Study of Diet and Food Security of Older Adults Across New York City Boroughs: Implications for Cognitive Decline. American Journal of Public Health Research, 2024; 12(4):81-86. doi: 10.12691/ajphr-12-4-3

  6. Tia Jeffery, Amy Schweitzer, Lillie Monroe-Lord, and Carolyn Miller (2025), Hybrid Delivery of a Heritage-Based Nutrition Program for Black Older Adults, Health Promotion Practice, https://doi.org/10.1177/15248399251354955

  7. Lillie Monroe-Lord, Azam Ardakani, Amy Schweitzer, Elmira Asongwed, Xuejing Duan, Tia Jeffery, Phronie Jackson, Elgloria Harrison, and Eyerusalem Beza (2025), Demographic Determinants of Food Insecurity in Older Adults During the COVID-19 Pandemic, Nutrients, 17 (18) 2934. https://doi.org/10.3390/nu17182934

  8. Lillie Monroe-Lord, Azam Ardakani, Xuejing Duan, Elmira Asongwed, Tia Jeffery, and Phronie Jackson (2025) Impact of Socioeconomic Factors on Post-COVID-19 Dietary Changes: Analysis Across Income and Education Levels: American Journal of Public Health Research, Vol. 13, No. 4, 152-164. DOI: 10:12691/ajphr-13-4-2

  9. Tia Jeffery, Xuejing Duan, Azam Ardakani, Sapna Batheja, Gifty N. Stevinson and Lillie Monroe-Lord (2025) Patterns of US Citizenship Status VS. Diet Quality Among Adults of African Decent: BMC Nutrition; 11: 136, 1754. https://doi.org/10.1186/s40795-025-01108-z

  10. Lillie Monroe-Lord, Azam Ardakani, Ricardo Brown, Elmira Asongwed, Xuejing Duran, Tia Jeffery, and Phronie Jackson (2025) Changes in Food Consumption Patterns After the Onset of the COVID-19 Pandemic Based on Age and Sex, Nutrients; 17 (11), 1754, https://doi.org/10.3390/nu17111754

  11. Moosavi, D.A. Mullens, L.A. Davidson, Y.Y. Fan, J.S. Goldsby, I.V. Ivanov, L. Levy, O.J. Kahsai, K.R. Curtis, D. Raftery, H.J. Purcell, E. Mather, H. Ammar, T. Randolph, R.B. Issaka, S.L. Navarro, J.W. Lampe, M.A. Hullar, and R.S. Chapkin. Gut microbial community and host intestinal gene expression with combined fish oil and soluble corn fiber compared with corn oil and maltodextrin: a randomized crossover trial in healthy older individuals. American Journal of Clinical Nutrition 122:396-412. 2025. PMID: 40754387.

  12. Schultz, S., Francis, S. L., Bauman, A., Vincent, A. D., & Hyde, C. Training Needs and Preferences of the Senior Nutrition Program Network: Amplifying Historically Marginalized Voices. Journal of applied gerontology: the official journal of the Southern Gerontological Society, 7334648251347406. Advance online publication. https://doi.org/10.1177/07334648251347406

  13. Lu C**, Francis SL. β NEWS You Can Use— Helping Older Adults Make Informed Food Choices. Journal of Human Sciences and Extension, 12(3). https://scholarsjunction.msstate.edu/cgi/viewcontent.cgi?article=1501&context=jhse

  14. Nigg, J., Arendt, S., Sapp, S., Francis, SL. Food-related control and person-centered care: Influences on life satisfaction in long-term care residents. Journal of Nutrition in Gerontology and Geriatrics, 1-19. https://doi.org/10.1080/21551197.2024.2428660

  15. Shoemaker ME, Pereira SL, Mustad VA, Gillen ZM, McKay BD, Lopez-Pedrosa JM, Rueda R, Cramer JT. (2025). A pilot study evaluating differences in muscle tissue saturation and blood flow between older adults with and without sarcopenia. Frontiers in Endocrinology. 16. doi: 10.3389/fendo.2025.1644712

  16. Kutnik P, Ramos Da Silva BR, Shoemaker ME, Gonzalez Barbosa-Silva T, Gonzalez MC, Lobo DN, Prado C. (2025). Enhancing health outcomes through optimized body composition in prehabilitation. Annals of Nutrition and Metabolism. 10:1-10. doi: 10.1159/000545026. Epub ahead of print. https://pubmed.ncbi.nlm.nih.gov/40064158/

  17. Frankhouser DE, DeWess T, Snodgrass IF, Cole RM, Steck S, Thomas D, Kalu C, Belury MA, Clinton SK, Newman JW, Yee LD. Randomized dose-response trial of n-3 fatty acids in hormone receptor negative breast cancer survivors-impact on breast adipose oxylipin and DNA methylation patterns. Am J Clin Nutr. 2025; 25: S0002-9165. doi: 10.1016/j.ajcnut.2025.04.021. PMID: 40288580

  18. Madison AA, Shrout MR, Wilson SJ, Renna ME, Peng J, Andridge R, Jaremka LM, Fagundes CP, Belury MA, Malarkey WB, Kiecolt-Glaser JK. "I'm Ready This Time": Investigating physiological and emotional habituation to repetitive social stress. Ann Behav Med. 2025; 59: kaaf009. doi: 10.1093/abm/kaaf009.PMID: 40036285

  19. Ilayan A, Dustin D, Kowalski C, Belury MA, Johnson LK, Conrad Z.J. Micronutrient Inadequacy Differs by Intake of Fat Amount and Class Among Adults That Consume a Restricted Carbohydrate Diet: National Health and Nutrition Examination Survey, 2007-2018. Acad Nutr Diet. 2025 Apr;125(4):501-514.e1. doi: 10.1016/j.jand.2024.11.001. Epub 2024 Nov 7.PMID: 39521380


Published Research Abstracts (11 TOTAL)



  1. Lillie Monroe-Lord, Azam Ardakani, Phronie Jackson, Cassidy Weitman (2025) Socio-Demographic Determinants of Food Security Among Elderly Women During the COVID-19 Pandemic: Journal of Nutrition Education and Behavior 57 (8), S22, https://doi/10.1016/j.jneb.2025.05.050

  2. Lillie Monroe-Lord, Azam Ardekani, Phronie Jackson, Amy Schweitzer, Tia Jeffery, Cassidy Weitman (2025) Changes in Food Security Among Elderly Populations: The Role of Income Disparities During the COVID-19 Pandemic: Current Developments in Nutrition, 9 (2), 106303. https://doi.org/10.1016/j.cdnut.2025.106303

  3. Y Fan, M.L. Salinas, D.A. Mullens, L.A. Davidson, J.S. Goldsby, I.V. Ivanov, J.J. Cai, L. Levy, M.A. Hullar, S.L. Navarro, J.W. Lampe and R.S. Chapkin. Fish oil and soluble fiber reduce colon cancer risk by synergistically promoting targeted ferroptosis in preclinical mouse models and healthy human adults. Presented at the International Society for the Study of Fatty Acids and Lipids (ISSFAL) Meeting, Quebec City, Canada, June 29-July 2, 2025.

  4. M. Donovan, C.R. Martin, S.N. Taylor, D.A. Mullens, J.S. Goldsby, I. Ivanov, L.A. Davidson and R.S. Chapkin. Non-invasive assessment of molecular biomarkers of intestinal development in very preterm infants. NEC Symposium 2025, Chicago IL, September 7-10, 2025.

  5. Rudolph, C.**, Francis, S.L., Bauman, A. (2025). Leveraging Insights from Informal Caregivers: Awareness and Attitudes Toward Adult Community-Based Food and Nutrition Programs. Poster presentation for the SNEB Annual Conference, July 2025.

  6. Rudolph, C., Francis, S.L., Bauman, A. Community Resource Awareness and Referral Practices of Healthcare Providers to Support Older Adults. Poster presentation for the 2024 GSA Annual Conference

  7. Francis, S.L., Rudolph, C.**, Wood, E.C.**, Woodall, S. (2025). Aging Together: Multi-Sector Collaboration for Healthier Futures. Session presentation given at the SNEB Annual Conference, July 2025.

  8. Rudolph, C.**, Francis, S.L., & Bauman, A. (2024). Awareness and Attitudes Toward Senior Nutrition Programs Among Middle-Aged and Older Adults. 30-minute roundtable presentation to be given at the American Public Health Association Annual Meeting & Expo, October 2024

  9. Weidauer, L., Shoemaker, M., Francis, S.L., Xu, F., Delmonico, M., Venturra-Marra, M., Lofgren, I., Baum, J., Woolf, K., Monroe-Lord, L. StrengthenHER: A Remotely Delivered Sarcopenia Prevention Program.  Poster presentation given at the the SNEB Annual Conference, July 2025.

  10. Shoemaker ME, Northrup MJ, Barry, AM. Student-led nutrition and physical activity program to promote healthier aging. Poster presentation at ISBNPA 2025 Annual Meeting, Auckland, New Zealand, June 11-14.

  11. Vaezi S, Shoemaker ME, Freeling JL, Sanders WM, Dey M. A low-ultra-processed, plant-forward diet with lean red meat enhances metabolic health in older adults at risk for insulin resistance. Poster presentation at Nutrition 2025, American Society of Nutrition (ASN), Orlando, FL, May 31-June 3, 2025.


Invited Talks (2 TOTAL)



  1. Invited Speaker: National Pork Board/American Society for Nutrition – Nutrition 2025, Orlando, FL Rethinking the Plate: Leveraging Food Traditions and Flavor for Dietary Guidelines Adherence Title: Optimizing Protein and Nutrient Intake: A Pathway to Better Diet Quality and Guideline Adherence June 2025

  2. Invited Speaker: Indiana University Graduate Nutrition Program – Feb 12thTitle: Protein Intake and Appetite Regulation: Mechanisms, Benefits, and Implications 2025


 Grants and Contracts (16 TOTAL; $1,747,915 total awarded)



  1. Funding Period: August 1, 2025 through July 31, 2028  Title of Grant: Affordability, Nutrition, And Health - The Role of Dietary Protein in Diverse Dietary Patterns Across the Lifespan. Funder: USDA NIFA. Grant Amount: $299,940  Role: Jamie I. Baum, PI



  1. Period of Funding: September 1, 2025 through August 31, 2028. Title of Grant: Exploring the Impact of Pulse Consumption as Part of a Healthy Diet on Cardiometabolic Health Outcomes in Older Adults with Overweight/Obesity: The Role of Inflammation and Gut Microbiome. Funder: USDA Pulse Crop Health Initiative. Grant Amount: $325,000 Role: Jamie I. Baum, PI



  1. Period of Funding: January 1, 2025 - December 31, 2025. Title of Grant: Development and assessment of sustainable protein-based products for metabolic support throughout the lifespan. Funder: University of Arkansas Honors College Research Grant Award Grant Amount: $5,500 Role: Jamie I. Baum, PI



  1. Funding Period: 9/2023-5/2028. Title of Grant: Nutritional and clinical predictors of intestinal maturation and feeding tolerance in the preterm infant. Funder: NIH. Name of PD/PI:  Donovan/Chapkin. Grant Amount:  $3,421,966



  1. Funding Period: October 1, 2021 – September 30, 2026 (concluded early)  Title of Grant: National Resource Center on Nutrition and Aging: A partnership with Iowa and the Administration on Community Living (ACL) Funder: DHHS, ACL. Grant Amount: $4,909,899 (Total received by Iowa Department of Health and Human Services, Division on Aging and Disabilities); ISU Overall portion: $1,211,579  (2024-25 total is $282,981)  Role: Sarah L. Francis ISU Principal Investigator (PI)



  1. Funding Period: October 2012 – Present. Title of Grant: Wellness and Independence through Nutrition (WIN): SNAP Outreach Funder: Iowa Department of Human Services Grant Amount: $56,070.55 Role: Sarah L. Francis, PI



  1. Funding Period: October 1, 2024 through September 30, 2029. Title of Grant: Partnership StrengthenHer: Empowering women through a community-based virtual sarcopenia prevention program.  Funder: National Institute of Food and Agriculture (AFRI) Competitive Grant, United States Department of Agriculture  Grant Amount: $1,091,218. Role:  Lee Weidauer, PI



  1. Period Oct 2024-Oct 2026. Title: Prevention of Cancer Cachexia by Dietary Naringenin: Impact on the Gut-Brain Axis. Funder: Cancer Center and CFAES Role: PI     



  1. Period: Sep 2023- Sep 2028. Title: Improving Sarcopenia by Targeting Mitochondria Funder: NIA/NIH R01    AG080184  Amount: $3,049,000 Role: MPI



  1. Period: Apr 2023 – Apr 2026 Title: Walnuts, The Gut-Brain Axis and Cognitive Function Funder: USDA NIFA #2022-07315 Amount: $300,000 Role: PI                                                                            



  1. Period: Mar 2024 – Feb 2029 Title: Contributions of Adipose Tissue to the Development of Pancreatic Cancer Funder: NIH/NCI Amount: $3,000,000  Role: Co-I



  1. Mar 2023 – Feb 2028 Title: Fecal microbial transplantation for chemotherapy behavioral side effects Funder: NIH/NCI Amount:$3,000,000 Role: Co-I



  1. Period: Jan 2023 – Dec 2026 Title: Uncovering the Feedback Loop Between the Central Nervous System and Adipose Tissue Funder: W. M. Keck Foundation Amount:  $ 1,400,000 Role: Co-I



  1. Funding Period: August 1, 2025 - July 31, 2028 Title of Grant: Affordability, Nutrition, And Health - The Role of Dietary Protein in Diverse Dietary Patterns Across the Lifespan Funder: USDA NIFA-AFRI Grant Amount: $300,000 Role: Jamie I. Baum, PI



  1. Funding Period: September 1, 2025 through August 31, 2028 Title of Grant: Exploring Impact of Pulse Diet on Cardiometabolic Health Outcomes in Overweight/Obesity Older Adults: Role of Inflammation and Gut Microbiome Funder: USDA Pulse Crop Health Initiative Grant Amount: $310,000 Role: Jamie I. Baum, PI                                                  

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