Brief Summary of Minutes of Annual Meeting

Objective 1: Identify, develop, and/or validate trace residue analytical methods, immunological procedures, and biomarkers 

Hawaii, Li: π-Cation Interactions in Molecular Recognition and Design. The π-cation interaction that differs from the cation-π interaction is a valuable concept in molecular design of drugs and pesticides. In this report we present an up-to-date review (1995 to 2017) on bioactive molecules involving π-cation interactions with the recognition site, and categorize into systems of inhibitor-enzyme, ligand-receptor, ligand-transporter, and hapten-antibody. The concept of π-cation interactions offers use of π systems in a small molecule to enhance the binding affinity, specificity, selectivity, lipophilicity, bioavailability, and metabolic stability, which are physiochemical features desired for drugs and pesticides.

California, Gan: A Tiered Framework to Evaluating Accumulation of Emerging Contaminants in Food Crops. Irrigation with treated wastewater and application of biosolids or animal waste introduce numerous contaminants of emerging concern (CECs) into agroecosystems. Accumulation of CECs in food produce constitutes a potential food safety and human health risk. However, a comprehensive risk assessment and management of CECs in agroecosystems is constrained by multiple factors, the utmost of which is the enormous number and diverse characteristics of CECs.  In this perspective, we briefly summarize the current knowledge on accumulation of CECs in plants including vegetables. We then delineate processes contributing to the ultimate accumulation of CECs in edible tissues in the soil-plant continuum. We outline a tiered framework as the path forward to prioritize CECs that may have a high risk for accumulation in food produce. This tiered approach is valuable as it helps us focus our research efforts only on the priority CECs and thus maximizes the use of our limited research resources to tackle this urgent issue.

Objective 2: Characterize abiotic and biotic reaction mechanisms, transformation rates, and fate in agricultural and natural ecosystems

Louisiana, Armbrust: Advanced Experiments to Investigate Pesticide Fate Processes in Shallow Water Aquatic Systems. Shallow water aquatic systems are relevant to many areas in agriculture.  Some agricultural settings, such as rice culture, make use of these directly to control weeds and other agricultural pests.  They are also employed in aquaculture for many marine species (fish, crabs, shrimp) as well as freshwater aquaculture (catfish, crawfish) and can serve as breeding grounds freshwater and marine organisms and serve as breeding grounds for juvenile organisms. The purpose of the present and ongoing investigation is to use shallow irradiated water-sediments systems to simulate degradation processes influenced by sunlight in shallow aquatic habitats such as rice fields and estuarine systems receiving agricultural runoff, hydroxyl radical rate constants to capture degradation rate information for chemicals susceptible to this process, and phototoxicity experiments on freshwater and marine fish as well as an economically important invertebrate, red swamp crawfish.  Many of these processes are not captured in the standard battery of tests submitted by registrants for pesticide registration, but can be captured by these systems and potentially simulated exposure models used by the US EPA.  The present work is focusing on selected rice herbicides as well as the fungicide dicloran.

USDA ARS Maryland, Hapeman: Launching a National Study to Age-date Stream Waters using Chiral MESA. Agricultural activities can be significant non-point sources of nutrient pollution to surface waters, and various conservation practices and remediation methods have been implemented to control and remediate these nutrient losses. Evaluating their effectiveness on mitigating delivery of groundwater pollutants to surface waters requires reliable dating methods to measure groundwater residence times. Several approaches have been utilized to improve these estimates, including isotopic ratio changes in nitrate or water, fortuitous detection of soluble anthropogenic compounds (e.g., CFCs, SF6), or gaseous analysis, but significant uncertainties still exist. Furthermore, these methods cannot be used in waters exposed to atmosphere, such as streams and lakes. Recently, we have discovered a method to estimate the age of groundwater under agricultural lands based on the mean residence time and the change in the chirality ratio of MESA (metolachlor ethane sulfonic acid, 2-[(2-ethyl-6-methylphenyl)(2-methoxy-1-methylethyl)amino]-2-oxoethanesulfonic acid), a degradation product of the herbicide metolachlor (2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide).

Objective 3: Determine adverse impacts from agrochemical exposure to cells, organisms, and ecosystems

Indiana, Sepulveda:  Effects of Per/Polyfluoroalkyl Substance (PFAS) Exposure on Larval Eastern Tiger Salamanders (Ambystoma tigrinum) and American Toads (Anaxyrus americanus). Per/polyfluoroalkyl substances (PFASs) are a ubiquitous group of anthropogenic environmental toxicants. Decades of production and use in a variety of applications has led to contamination of surface waters across the globe. Many species of wildlife are exposed to these compounds with unknown effects, though research suggests exposure may result in disruption of thyroid hormone regulation. Since thyroid hormone is a primary driver of amphibian metamorphosis, amphibians may represent a group of at-risk animals due to PFAS exposure. With this in mind, we chronically exposed larval eastern tiger salamanders (Ambystoma tigrinum) and American toads (Anaxyrus americanus) to four different PFASs (perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), perfluorohexane sulfonate (PFHxS) and 6:2 fluorotelomer sulfonate (6:2 FtS)). First, we determined time to steady-state by conducting a 40-day uptake study and examining body burdens and bioconcentration of PFAS when exposed via contaminated water. A following study examined effects on growth, body condition, and thyroid gland development. For all compounds, uptake was rapid and a steady-state body burden was generally achieved in 10 d or less. Only PFOS showed significant bioconcentration (up to 117.7 at 10 d, all others were <10 throughout exposure). Salamanders in all treatment groups were found to have body condition indices below control levels, with significance for low dose (10 µg/L PFAS in water) PFOA and PFHxS, as well as mid and high-dose (100 and 1000 µg/L) 6:2 FtS. No reductions in growth or body condition were noted for toads. Thyroid gland development was only appreciable in toads at the developmental stages examined; no effects of PFAS exposure were noted on thyroid gland histology. The reduction in body condition of salamanders exposed to low doses of PFASs is of concern and may adversely affect populations of this species in nature.

 Objective 4: Develop technologies that mitigate adverse human and environmental impacts

USDA ARS South Dakota, Papiernik: Summer Fertigation of Dairy Slurry Reduces Subsurface Drainage Nitrate Losses Compared to Fall Injection. Leaching of nitrate (NO₃-N) from manure-applied cropping systems can represent a substantial route of nitrogen loss to the environment for dairy farms, particularly in fields with artificial subsurface drainage. In this on-farm study, we used a Before/After analysis to assess the effectiveness of summer fertigation with reduced manure rates versus fall injection of dairy slurry in terms of subsequent corn silage yield, corn N removal, soil NO₃-N distribution, and NO₃-N losses in subsurface tile drainage from a 65-ha field in Minnesota. Here, we present the results for NO₃-N losses. Weekly flow-weighted mean NO₃-N concentration in tile drainage was lower during fertigation (47.7 mg L-1) than injection (56.8 mg L-1), although mean weekly drainage depth was greater during fertigation (2.3 versus 1.1 mm). Results suggest that summer fertigation with attendant reduction in application rate is a viable method for reducing drainage NO₃-N losses without impacting yield of irrigated silage corn in the U.S. Midwest.

 Oregon, Jenkins: Probabilistic Methods to Evaluate the Relationship between Chlorpyrifos Use at the Watershed Scale and Impacts on Aquatic Resources. Pesticide surface water monitoring beginning in the early 1990’s has led to the identification of the Zollner Creek watershed, located in the Willamette Valley, OR, one of the most contaminated surface waters in the state of Oregon. Zollner Creek was monitored for pesticides from 1993-2008 by the USGS as part of the National Water Quality Assessment Program (NAWQA). Starting in 2005, the Oregon Department of Environmental Quality (ODEQ) began monitoring in the Zollner Creek watershed as part of the Pesticide Stewardship Partnership (PSP). For this study, a probabilistic approach was used to characterize use practices of the organophosphate insecticide chlorpyrifos in the Zollner Creek watershed located in the Willamette Valley of Oregon between 2010 and 2011. The Soil and Water Assessment Tool (SWAT) was used to simulate the fate and transport of chlorpyrifos applied in the watershed and estimate aqueous exposure concentrations over a continuous 2 year period. The estimated exposure concentrations were used in conjunction with a Tier 1 Daphnia magna theoretical population model to evaluate the effect on population growth dynamics over the 2 year period. Daphnia magna was chosen as a sensitive species within the salmonid food web.

Journal Articles

1. Janney, P. K., J. J. Jenkins. 2018. Modeling ecohydrology in the Zollner Creek watershed, Oregon USA – a systems approach to evaluating the impact of agricultural practices on water resources. Submitted to Journal of Environmental Quality.
2. Hall, K. E., K. A. Spokas, B. Gamiz, L. Cox, S. K. Papiernik, and W. C. Koskinen. Glyphosate sorption/desorption on biochars – Interactions of physical and chemical processes. Pest Manag. Sci. 74: 1206-1212. 2017.
3. Sandhu, S. S., D. A. N. Ussiri, S. Kumar, R. Chintala, S. K. Papiernik, D. D. Malo, and T. E. Schumacher. Analyzing the impacts of three types of biochar on soil carbon fractions and physiochemical properties in a corn-soybean rotation. Chemosphere 184:473-481. 2017.
4. Gamble, J. D., G. W. Feyereisen, S. K. Papiernik, C. Wente, and J. Baker. Regression-kriged soil organic carbon stock changes in manured corn silage–alfalfa production systems. Soil Sci. Soc. Am. J. 81:1557-1566. 2017.
5. Gamble, J., G. W. Feyereisen, J. M. Baker, S. K. Papiernik, and C. D. Wente. Summer fertigation of dairy slurry reduces soil nitrate concentrations and subsurface drainage nitrate losses compared to fall injection. Front. Sustain. Food Syst. 2:15. 2018.
6. Papiernik, S. K., T. W. Sappington, R. G. Luttrell, L. S. Hesler, and K. C. Allen. Overview: Risk factors and historic levels of pressure from insect pests of seedling corn, cotton, soybean, and wheat in the U.S. J. Integrated Pest Manag. In press.
7. Sappington, T. W., L. S. Hesler, K. C. Allen, R. G. Luttrell, and S. K. Papiernik. Prevalence of sporatic insect pests of seedline corn and factors affecting risk of infestation. J. Integrated Pest Manag. In press.
8. Hesler, L. S, K. C. Allen, R. G. Luttrell, T. W. Sappington, and S. K. Papiernik. Early-season pests of soybean in the United States and factors that affect their risk of infestation. J. Integrated Pest Manag. In press.
9. Allen, K. C., R. G. Luttrell, T. W. Sappington, L. S. Hesler, and S. K. Papiernik. Frequency and abundance of selected early-season insect pests of cotton. J. Integrated Pest Manag. In press.
10. Wang, ; Peng, J.; Li, Q.X.; Peng, Y-L. 2017. Phosphorylation-mediated regulatory networks in mycelia of Pyricularia oryzae revealed by phosphoproteomic analyses. Molecular and Cellullar Proteomics 16: 1669-1682.
11. Lv,; Zhang, J.; Shi, T.; Dai, L.; Li, X.; Wu, X.; Li, X.; Tang, J.; Li, Q.X.; Hua, R. 2017. Procyanidolic oligomers enhance photodegradation of chlorothalonil in water via reductive dechlorination. Applied Catalysis B: Environmental 217: 137-143.
12. Wang, ; Zhu, M.; Jiang, E.; Hua, R.; Na, R.; Li, Q.X. 2017. A simple and rapid turn on ESIPT fluorescent probe for colorimetric and ratiometric detection of biothiols in living cells. Scientific Reports 7(1):4377.
13. Wu, ; Sun, Z.; Shi, T.; Pan, D.; Xue, J.; Li, Q.X.; Hua, R. 2017. Influence of plant growth regulating substances on transport and degradation of acephate and its metabolite methamidophos in tomato. Int’l J. of Environmental Analytical Chemistry 97(4): 345-354.
14. Wu, ; Xue, J.; Pan, D.; Jin, L.; Shi, T.; Cheng, X.; Li, Q.X.; Hua, R. 2017. Dissipation and residue of acephate and its metabolite metamidophos in peach and pear under field conditions. Int’l J. of Environmental Research 11(2): 133–139.

15. Xie,; Zhao, C.; Han, Q.; Zhou, H.; Li, Q.X.; Diao, X. 2017. Effects of pyrene exposure on immune response and oxidative stress of the pearl oyster, Pinctada martensii. Fish Shellfish Immunol. 63: 237-244.
16. Chen, ; Chen, C.; Yoza, B.A.;· Li, Q.X.;· Guo, S.; Wang, P.; Dong, S.; Wang, Q.H. 2017. Efficient ozonation of reverse osmosis concentrates from petroleum refinery wastewater using composite metal oxide loaded alumina supports. Petroleum Science 14: 605-615.
17. Chen,; Liang, J.; Yoza, B.A.; Li, Q.X.; Zhan, Y.; Wang, Q. 2017. Evaluation of an up- flow anaerobic sludge bed (UASB) reactor containing diatomite and maifanite for the improved treatment of petroleum wastewater. Bioresource Technology 243: 620-627.
18. Wang, ; Boesch, R.; Li, Q.X. 2017. A case study of air quality - pesticides and odorous phytochemicals on Kauai, Hawaii, USA. Chemosphere 189: 143-152.
19. Cho, K.; Park, B.-J.; ·Chung, K.H.; Li,Q.X.; Kan, E. 2017. Fenton oxidation of bisphenol A using an Fe3O4-coatedcarbon nanotube: Understanding of oxidation products, toxicity and estrogenic activity. Korean Journal of Pesticide Science 21(3): 310-315.
20. Ye, ; Ching, T.H.; Yoza, B.A., Masutani, S.; Li, Q.X. 2017. Cometabolic degradation of blended biodiesel by Moniliella wahieum Y12Tand Byssochlamys nivea M1. International Biodeterioration & Biodegradation 125: 166-169.
21. Wang, ; Geng, A.; Dong, Y.; Fu, C.; Li, H.; Zhao, Y.; Li, Q.X.; Wang, F. 2017. Comparison of translocation and transformation from soil to rice and metabolism in rats for four arsenic species. Journal of Agricultural and Food Chemistry 65 (41): 8992–8998.
22. Cao, ; Zhang, W.; Ning, X.; Wang, B.; Liu, Y.; Li, Q.X. 2017. Development of monoclonal antibodies recognizing linear epitope: illustration by three Bacillus thuringiensis crystal proteins of genetically modified cotton, tobacco and maize. Journal of Agricultural and Food Chemistry 65(46): 10115-10122.
23. Pan, ; Li, Q.X.; Lin, Z.; Chen, Z.; Tang, W.; Tan, H.; Pan, C.; Zeng, D. 2017. Interactionsbetween salicylic acid and antioxidant enzymes tilting the balance of H2O2 from photorespiration in nontarget-crops under halosulfuron-methyl stress. Pesticide Biochemistry and Physiology 143: 214-223.
24. Clukey, E.; Lepczyk, C.A.; Balazs, G.H.; Work, T.M.; Li, Q.X.; Bachman, M.J.; Lynch,
25. 2018. Persistent organic pollutants in fat of three species of Pacific pelagic longline caught sea turtles: Accumulation in relation to ingested plastic marine debris. Science of the Total Environment 610-611:402-411.
26. Chen, ; Yan, X.; Yoza, B.A; Zhou, T.; Li, Y.; Zhan, Y.; Wang, Q,; Li, Q.X. 2018. Efficiencies and mechanisms of ZSM-5 zeolites loaded with cerium, iron, or manganese oxides for catalytic ozonation of nitrobenzene in water. Science of the Total Environment 612: 1424–1432.
27. Liu,; Pan, D.; Wu, X.; Chen, H.; Cao, H.; Li, Q.X.; Hua, R. 2018. Enhanced degradation of prometryn and other s-triazine herbicides in pure cultures and wastewater by polyvinyl alcohol-sodium alginate immobilized Leucobacter sp. JW-1. Science of the Total Environment 615: 78-86.

27. Li, ; Li, Y.; Pan, X.; Li, Q.X.; Chen, R.; Li,X.; Pan, C.; Song, J. 2018. Comparison of a new air-assisted sprayer and two conventional sprayers in terms of deposition, loss to the soil and residues of azoxystrobin and tebuconazole applied to sunlit greenhouse tomato and field cucumber. Pest Management Science 74(2): 448-455.
28. Sun, ; Pan, D.; Liu, J.; Wu, X.; Hua, R.; Li, Q.X. 2018. Leucobacter prometrynivorans sp. nov., a prometryn-degrading bacterium isolated from sludge. International Journal of Systematic and Evolutionary Microbiology 68: 204-210.
29. Islam, ; Wang, J.; Farooq, M.A.; Khan, M.S.S.; Xu, L.; Zhu, J.; Zhao, M.; Muños, S.; Li, Q.X.; Zhou, W. 2018. Potential impact of the herbicide 2,4-dichlorophenoxyacetic acid on human and ecosystems. Environmental International 111: 332-351.
30. Lv, ; Chen, Y.; Zhao, Z.; Shi, T.; Wu, X.; Li, Q.X.; Hua, R. 2018. Design, synthesis and antifungal activities of 3-acyl thiotetronic acid derivatives: New fatty acid synthase inhibitors. Journal of Agricutlrual and Food Chemistry 66(4): 1023–1032.
31. Fu, ; Xu, T.; Cui, Z.; Ng, Ho, L.; Wang, K.; Li, J.; Li, Q.X. 2018. Mutation of phenylalanine-223 to leucine enhances transformation of benzo[a]pyrene by ring- hydroxylating dioxygenase of Sphingobium sp. FB3 by increasing accessibility of the catalytic site. Journal of Agricultural and Food Chemistry 66(5): 1206-1213.
32. Zhang, ; Zhou, L.; Li, Q.X.; Liang, H.; Qin, H.; Masutani, S.; Yozae, B. 2018. Toxicity of lanthanum oxide nanoparticles to the fungus Moniliella wahieum Y12T isolated from biodiesel. Chemosphere 199: 495-501.
33. Chu, ; Baker, M.R.; Leong, G.; Letcher, R.J.; Li, Q.X. 2018. Covalent binding of the organophosphate insecticide profenofos to tyrosine on α- and β-tubulin proteins. Chemosphere 199: 154-159.
34. Wang, ; Ma, W.; Yoza, B.A.; Xu, Y.; Li, Q.X.; Chen, C.; Wang, Q.; Gao, Y.; Guo, S.; Zhan, Y. 2018. Investigation of catalytic ozonation of recalcitrant organic chemicals in aqueous solution over various ZSM-5 zeolites. Catalysts 8(4): 128.
35. Sanchis, ; Salvador, J.-P.; Campbell, K.; Elliott, C.T.; Shelver, W.L.; Li, Q.X.; Marco, M.-
36. 2018. Fluorescent Microarray for Multiplexed Quantification of Environmental Contaminants in Seawater Samples. Talanta 184: 499-506.
37. Wang, ; Liu, J.; Zhu, M.; Wang, L.; Zen, X.; Fan, S.; Wang, Z.; Li, H.; Na, R.; Zhao, X.; Li, Q.X. 2018. Biophysical characterization of interactions between falcarinol-type polyacetylenes and human serum albumin via multispectroscopy and molecular docking techniques. Journal of Luminescence 200: 111-119.
38. Chen,; Xianyang Yao, C.; Li, Q.X.; Wang, Q.; Liang, J.; Zhang, S.; Ming, J.; Liu, Z.; Deng, J.; Yoza, B.A. 2018. Turf soil enhanced treatment of phenolic wastewater using an up-flow anaerobic sludge blanket (UASB) reactor. Chemosphere 204: 227-234.
39. Wang, ; Na, R.; Zhu, M.; Jiang, E.; Wang, L.; Fan, S.; Wang, Z.; Li, Q.X.; Hua, R. 2018. A colorimetric and ratiometric dual-site fluorescent probe with 2,4-dinitrobenzenesulfonyl aldehyde groups for imaging of aminothiols in living cells and zebrafish. Dyes and Pigments 156: 338-347.

39. Nzila, ; Ortega Ramirez, C.; Musac, M.M.; Sankaraa, S.; Chanbashac, B.; Li, Q.X. 2018. Pyrene biodegradation and proteomic analysis in Achromobacter xylosoxidans, PY4 strain. International Biodeterioration & Biodegradation 130: 40-47.
40. Fu, Q.G., Q.F. Ye, J. Richards, and J. Gan. 2017. Metabolism of diclofenac in Arabidopsis thaliana cells: Dominance of conjugates and non-extractable residues. Environmental Pollution 222: 383-392.
41. Lao, W.J., Y.W. Hong, D. Tsukada, K. Maruya, and J. Gan. 2016. A new film-based passive sampler for moderately hydrophobic organic compounds. Environmental Science & Technology 50: 13470-13476.
42. Liao, C.Y., A.R. Taylor, W.F. Kenney, M. Brenner, D. Schlenk, and J. Gan. 2017. Historical record and fluxes of DDTs and PCBs at the Palos Verdes Shelf Superfund site, California. Science of the Total Environment 581-582: 697-704.
43. Lin, K.D., W.J. Lao, Z.J. Lu, F. Jia, K. Maruya, and J. Gan. 2017. Measuring freely dissolved DDT and metabolites in seawater using solid-phase microextraction with performance reference compounds. Science of the Total Environment 599-600: 364-371.
44. Xue, J.Y., C.Y. Liao, J. Wang, Z. Cryder, T.B. Xu, F.M Liu, and J. Gan. Development of passive samplers for in situ measurement of pyrethroid insecticides in surface water. Environmental Pollution 224: 516-523.
45. Fu, Q.G., J.B. Zhang, Schlenk, D. Borchardt, and J. Gan. 2017. Direct conjugation of emerging contaminants in higher plants: An overlooked risk? Environmental Science & Technology 51: 6071-6081.
46. Coffin, S., J. Gan, and D. Schlenk. 2017. The use of an isotope dilution method to estimate risk of DDTs from contaminated sediments to humans that consume fish in Palos Verdes, California, USA. Science of the Total Environment 601-602: 1139-1146.
47. Ding, T.D., M.T. Yang, J.M. Zhang, K.D. Lin, J.Y. Li, and J. Gan. 2017. Toxicity, degradation and metabolic fate of ibuprofen on freshwater diatom Navicula sp. Journal of Hazardous Materials 330: 127–134.
48. Cheng, Z.P., F.S. Dong, J. Xu, X.G. Liu, X.H. Wu, Z.L. Chen, X.L. Pan, J. Gan, Y.Q. Zheng. 2017. Simultaneous determination of organophosphorus pesticides in fruits and vegetables using atmospheric pressure gas chromatography quadrupole-time-of-flight mass spectrometry. Food Chemistry 231: 365–373.
49. Pennington, M.J., J.A. Rothman, M.B. Jones, Q.S. McFrederick, J. Gan, and J.T. Trumble. 2017. Effects of contaminants of emerging concern on Megaselia scalaris (Lowe, Diptera: Phoridae) and its Microbial Community. Scientific Reports 7: 8165, DOI:10.1038/s41598-017-08683-7
50. Ding, T.D., K.D. Lin, B. Yang, M.T. Yang , J.Y. Li, W.Y. Li, and J. Gan. 2017. Biodegradation of naproxen by freshwater algae Cymbella and Scenedesmus quadricauda and the comparative toxicity. Bioresource Technology 238: 164-173.
51. Sanganyado, E., Z.J. Lu, Q.G. Fu, D. Schlenk, and J. Gan. 2017. Chiral pharmaceuticals: A review on their environmental occurrence and fate processes. Water research 124: 527-542.
52. Bertotto, L., J. Richards, J Gan, D. Volz, and D. Schlenk. 2018. Effects of bifenthrin exposure on the estrogenic and dopaminergic pathways in zebrafish embryos and juveniles. Environmental Toxicology & Chemistry 37: 236-246.
53. Liao, C.Y., J. Richards, A. Taylor, and J. Gan. 2017. Development of polyurethane-based passive samplers for ambient monitoring of urban-use insecticides in water. Environmental Pollution 231: 1412-1420
54. Sun, C.L., S. Dudley, and J. Gan. 2018. Pharmaceutical and personal care products-induced stress symptoms and detoxification mechanisms in cucumber plants. Environmental Pollution 234: 39-47.
55. Pennington, M.J., J.A. Rothman, S. L. Dudley, M. B. Jones, Q. S. McFrederick, J. Gan, and J. T. Trumble. 2017. Contaminants of emerging concern affect Trichoplusia ni growth and development on artificial diets and a key host plant. Proceedings of National Academy of Science USA. 9923–9931 (pnas.org/cgi/doi/10.1073/pnas.1713385114)
56. Ding, T.D., K.D. Lin, M.T. Yang, L.J. Bao, J.Y. Li, B. Yang, and J. Gan. Biodegradation of triclosan in diatom Naviculasp.: Kinetics, transformation products, toxicity evaluation and the effects of pH and potassium permanganate. Journal of Hazardous Materials 344: 200-209.
57. Richards, J., Z.J. Lu, Q.G. Fu, D. Schlenk, and J. Gan. Conversion of pyrethroid insecticides to 3-phenoxybenzoic acid on urban hard surfaces. Environmental Science & Technology Letters 4: 546-550.
58. Wang, J., A. Taylor, C.Y. Xu, D. Schlenk, and J. Gan. 2018. Evaluation of different methods for assessing bioavailability of DDT residues during soil remediation. Environmental Pollution 238: 462-470.
59. Wang, J., A. Taylor, D. Schlenk, and J. Gan. 2018. Development of isotope dilution method (IDM) for predicting bioavailability of hydrophobic organic pollutants in soil. Environmental Pollution 236: 871-877.
60. Fu, Q.G., C.Y. Liao, D. Schlenk, and J. Gan. 2018. Back conversion from product to parent: Methyl triclosan to triclosan in plants. Environmental Science & Technology Letters 5: 181-185.
61. Pennington, M., J.A. Rothman, M.B. Jones, Q.S McFrederick, J. Gan, and J.T. Trumble. 2018. Effects of contaminants of emerging concern on Myzus persicae (Sulzer, Hemiptera: Aphididae) biology and on their host plant, Capsicum annum. Environmental Monitoring and Assessment 190: 125 (1-11).
62. Ding, T.D., K.D. Lin, L.J. Bao, M.T. Yang, J.Y. Li, B. Yang, and J. Gan. 2018. Biouptake, toxicity and biotransformation of triclosan in diatom Cymbella sp. and the influence of humic acid. Environmental Pollution 234: 231-242.
63. Sun, C.L., S. Dudley, M. McGinnis, and J. Gan. Hydrogen peroxide mediated root growth inhibition in wheat by triclosan. Environmental Pollution (in press)
64. Wang, J., K.D. Lin, A. Taylor, and J. Gan. In vitro Assessment of pyrethroid bioaccessibility via particle ingestion. Environment International (in press).
65. Zhai, Y.W., X.H. Xia, X.Y. Xiong, L.Z. Xia, X.J. Guo, and J. Gan. 2018. Role of fluoranthene and pyrene associated with suspended particles in their bioaccumulation by zebrafish (Danio rerio). Ecotoxicology and Environmental Safety 157: 89-94.
66. Ding, T.D., K.D. Lin, J. Chen, Q. Hu, B. Yang, J.Y. Li, and J. Gan. 2018. Causes and mechanisms on the toxicity of layered double hydroxide (LDH) to green algae Scenedesmus quadricauda. Science of the Total Environment 635: 1004-1011. Romero-Flores, McConnell LL, Hapeman CJ, Ramirez M, Torrents A. 2017. Evaluation of an electronic nose for improved biosolids alkaline-stabilization treatment and odor management. Chemosphere 186:151-159.
67. Niño de Guzmán GT, Hapeman CJ, Millner PD, McConnell LL, Jackson D, Kindig D, Kjellerup B, Torrents A. 2018. Using a high-organic matter biowall to treat a trichloroethylene plume at the Beaver Dam Road Landfill. Environ Sci Pollut Res 25:8735-8746.
68. Spiegal S, Bestelmeyer BT, Archer DW, Augustine DJ, Boughton EH, Boughton RK, Cavigelli MA, Clark PE, Derner JD, Duncan EW, Hapeman CJ, Harmel RD, Heilman P, Holly MA, Huggins DR, King K, Kleinman PJA, Liebig MA, Locke MA, McCarty GW, Millar N, Mirsky SB, Moorman TB, Pierson FB, Rigby JR, Robertson GP, Steiner JL, Strickland TC, Swain HM, Wienhold BJ, Wulfhorst JD, Yost MA, Walthall CL. 2018. Sustainable intensification of U.S. agriculture: strategies, barriers, and the role of the Long-Term Agroecosystem Research network. Environ Res Lett 13:034031. DOI: https:10.1088/1748-9326/aaa779.
69. Yao Q, Yang Z, Li H, Buser MD, Wanjura JD, Downey PM, Zhang C, Craige C, Torrents A, McConnell LL, Holt GA, Hapeman CJ. 2018. Assessment of particulate matter and ammonia emission concentrations and respective plume profiles from a commercial poultry house. Env Pollut 238:10-16.
70. Ro KS, Li H, Hapeman CJ, Harper LA, Flesch TK, Downey PM, McConnell LL, Torrents A, Yao Q. 2018. Enhanced dispersion and removal of ammonia emitted from a poultry house using a vegetative environmental buffer. Agriculture 8:46. DOI:10.3390/agriculture8040046.

1. Abdel-moneim A, Mahapatra CT*, Sepúlveda MS. (2018). In vivo visual reporter system for estrogenic contaminant exposure using transgenic see-through Japanese medaka Oryzias latipes. Chemosphere 201:251-253. (IF = 4.20).
2. Rodgers ML, Jones ER, Klinkhamer C, Mahapatra CT*, Serafin J, Bosker T, Perkins C, Griffitt RJ, De Guise S, Sepúlveda MS. (2018). Combined effects of Deepwater Horizon crude oil and environmental stressors on Fundulus grandis embryos. Environmental Toxicology and Chemistry. In Press. (IF = 2.95).
3. Poynton HC, Hasenbein S, Benoit JB, Sepúlveda MS, Poelchau MF, Hughes DST, Murali SC, Chen S, et al. (2018). The Toxicogenome of Hyalella azteca: a model for sediment ecotoxicology and evolutionary toxicology. Environmental Science & Technology. In Press. (IF = 6.19).
4. Godfrey A, Hooser B, Abdel-moneim A, Horzmann KA, Freeman JL, Sepúlveda MS. (2017) Thyroid disrupting effects of halogenated and next generation chemicals on the swim bladder development of zebrafish. Aquatic Toxicology 193:228-235. (IF = 4.12).
5. Thurner K, Goforth RR, Chen S, Amberg J, Leis E, Kinsella JM, Mahapatra C, Sepúlveda MS. (2017) Viruses, bacteria and helminths of invasive carp: Insights from an in vitro assay and a survey with native fishes in a large Midwestern River. Journal of Fish Pathology 30:000-000. (IF = 2.05).
6. Chatuverdi P, Vanegas DC, Hauser BA, Foster JS, Sepúlveda MS, McLamore ES (2017) Microprofiling real time nitric oxide flux for field studies using a stratified nanohybrid carbon-metal electrode. Analytical Methods 42:6061-6072. (IF = 1.90).
7. Hoover GM, Chislock MF*, Tornabene BJ, Guffey SC, Choi YJ, De Perre C, Hoverman JT, Lee LS, Sepúlveda MS. (2017). Uptake and depuration of four per/polyfluoroalkyl substances (PFASs) in northern leopard frog Rana pipiens tadpoles. Environmental Science & Technology Letters 4:399-403. (IF = 5.30).
8. Abdel-moneim A, Deegan D, Gao J, Perre C, Doucette JS, Jenkinson B, Lee LS,  Sepúlveda MS. (2017) Gonadal intersex in smallmouth bass Micropterus dolomieu from northern Indiana with correlations to molecular biomarkers and anthropogenic chemicals. Environmental Pollution 230:1099-1107. (IF = 5.09).
9. Bosker T, van Balen Liselotte, Walsh B, Sepúlveda MS, DeGuise S, Perkins C, Griffitt R. (2017). The combined effect of Macondo oil and corexit on sheepshead minnow (Cyprinodon variegatus) during early development. Journal of Toxicology and Environmental Health Part A 80:477-484. (IF = 2.73).
10. Godfrey A, Abdel-moneim A, Sepúlveda MS. (2017) Acute mixture toxicity of halogenated chemicals and their next generation counterparts on zebrafish embryos. Chemosphere 181:710-712. (IF = 4.20).
11. Dunlop ES, McLaughlin R, Adams JV, Jones M, Birceanu O, Christie MR, Criger LA, Hinderer JLM, Hollingworth RM, Johnson NS, Lantz S, Li W, Mille J, Morrison BJ, Mota-Sanchez D, Muir A, Sepúlveda MS, Steeves T, Walter L, Westman E, Wirgin I, Wilkie MP. (2017) Rapid evolution meets invasive species control: the potential for pesticide resistance in sea l. Canadian Journal of Fisheries and Aquatic Sciences 75:152-168. (IF = 2.85).
12. Keller CEM, Sepúlveda MS, Hopf Jannasch A, Roumani AM, Zhou FC, Brown PB. (2017) Metabolite changes in the zebrafish model of fetal alcohol spectrum disorder associated with established neural abnormalities. The FASEB J. 31:792.1. (IF = 5.49).
13. Miles JC, Hua J, Sepúlveda MS, Krupke CH, Hoverman JT. (2017). Effects of clothianidin on aquatic communities: Evaluating the impacts of lethal and sublethal exposure to neonicotinoids. PLoS ONE 12, e0174171. (IF = 3.23).
14. Almeida LZ, Guffey SC, Sepúlveda MS, Höök TO. (2017) Behavioral and physiological responses of yellow perch (Perca flavescens) to moderate hypoxia. Comparative Biochemistry and Physiology. Part B: Biochemistry and Molecular Biology 209:47-55. (IF = 1.75).
15. Kar S, Sepúlveda MS, Roy K, Leszczynski J. (2017) Endocrine-disrupting activity of per- and polyfluoroalkyl substances: Exploring combined approaches of ligand and structure based modeling. Chemosphere 184:514-523. (IF = 4.20).
16. Mahapatra CT*, Damayanti NP, Guffey SC, Serafin SS, Irudayaraj J, Sepúlveda MS. (2017) Comparative in vitro toxicity assessment of perfluorinated carboxylic acids. Journal of Applied Toxicology 37:699-708. (IF = 3.15).
17. Gao J, Lin L, Wei A, Sepúlveda MS. (2017) Protein corona analysis of silver nanoparticles exposed to fish plasma. Environmental Science & Technology Letters 4:174-179. (IF = 5.30).

88. Estes, T. and Armbrust. (2018).  Development of a New Method for Estimating Runoff Curve Numbers.  Journal of Environmental Quality.  (submitted)
89. Xu, W.; E. Vebrosky, M. Richards and Armbrust (2018). Evaluation of Dicloran Phototoxicity using primary cardiomyocyte culture from Crassostrea virginica.  Science of the Total Environment 628-629:1-10.
90. Vebrosky, E.; Saranjampour, P; D.G. Crosby and Armbrust. (2018). Photodegradation of Dicloran in Freshwater and Seawater.  Journal of Agricultural and Food Chemistry.  66(11):2654-2659.
91. Saranjampour, P; E. Armbrust. (2018). Repeatability of n-octanol/water partition coefficient values between liquid chromatography measurement methods.  Environmental Science and Pollution Research DOI: 10.1007/s11356-018-1729-4.
92. Saranjampour, P; E. Vebrosky and Armbrust. (2017). Salinity impacts on water solubility and n-octanol/water partition coefficients of selected pesticides and oil constituents.  Environmental Toxicology and Chemistry 36(9): 2274-2280.
93. Sarajampour, P., Armbrust and BD. Marx. (2017).  Assessing the hydroxyl radical and volatilization roles in the aquatic fate of polycyclic aromatic sulfur-containing hydrocarbons.  Environmental Toxicology and Chemistry 36(8):1998-2004.