11/15/2007

Allred, C. A., Allred, K.F., Ju, Y.H., Doerge, D.R., and Helferich, W.G. (2004) Soy processing influences growth of estrogen-dependent breast cancer tumors. Carcinogenesis 25(9):1649-1657.


Allred, C.A., Allred, K.F., Ju, Y.H., Doerge, D.R., Schantz, S., Korol, D., and Helferich, W.G. (2004) Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats. Carcinogenesis 25:211-218.


Allred, C.D., Twaddle, N.C., Allred, K.F., Churchwell, M.I., Ju, Y.H., Helferich, W.G., and Doerge, D.R. (2005) Soy processing affects metabolism and disposition of dietary isoflavones in ovariectomized Balb/c mice. J. Agric. and Food Chem. 53(22):8542-8550.


Carter, O., Wang, R., Dashwood, W.M., Orner, G.A., Fisher, K.A., Lohr, C.V., Pereira, C.B., Bailey, G.S., Williams, D.E. and Dashwood, R.H. (2007) Comparisons of white tea, green tea, epigallocatechin-3-gallate and caffeine as inhibitors of PhIP-induced colonic aberrant crypts. Nutr. Cancer 58(1), 1-6.


Choi, S. P., Kang, M. Y., Koh, H. J., Nam, S. H., and Friedman, M. (2007) Anti-allergic activities of pigmented rice bran extracts in cell assays. J. Food Sci. 72 (9). S719-S727.


Coulombe, R.A. and Yip, S.M.. (2007) Heterologous expression of a cytochrome P450 from turkey liver that activates aflatoxin B1. In Poisonous Plants: Global Research and Solutions (K. Panter, T. Wierenga, J. Phister, eds.) CAB International, London. pp. 82-88.

DeAssis, S, Wang, M, Goel, S, Foxworth, A., Helferich, W.G. and Hilakivi-Clarke, L. (2006). Increased carcinogen-induced mammary tumorigenesis and activation of MAPK in obese (fa/fa) Zucker rats exposed to pregnancy hormonal environment. J. Nutr. 136(4):998-1004.


Degner S.C., M.Q. Kemp, Bowden GT, and Romagnolo, D.F. (2006) Conjugated Linoleic Acid AttenuatesCyclooxygenase-2 Transcriptional Activity via an Anti-AP-1 Mechanism in MCF-7 Breast Cancer Cells. J. Nutr.136:421-427.


Degner SC, Kemp MQ, Hockings JK, and Romagnolo,D.F. (2007) Cyclooxygenase-2 promoter activation by the aromatic hydrocarbon receptor in breast cancer MCF-7 cells: repressive effects of conjugated linoleic acid. Nutr Cancer. 59(2):248-57.


Friedman, M. (2007) Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas. Mol. Nutr. Food Res. 51 (1): 116-134.


Friedman, M., Henika, P. R., Levin, C. E., and Mandrell, R. E. (2007) Recipes for antimicrobial wine marinades against Bacillus cereus, Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella enterica. J. Food Sci. 72 (6): M207-M213.


Friedman, M., Mackey, B. E., Kim, H. J., Lee, I. S., Lee, K. R., Lee, S. U., Kozukue, E., and Kozukue, N. (2007) Structure-activity relationships of tea compounds against human cancer cells. J. Agric. Food Chem. 55 (2): 243-253.



Friedman, M., McQuistan, T., Hendricks, J. D., Pereira, C., and Bailey, G. S. (2007) Protective effect of dietary tomatine against dibenzo[a,l]pyrene (DBP)-induced liver and stomach tumors in rainbow trout. Mol. Nutr. Food Res. 51 (12), 185-1491.


Gray, J. S., and Pestka, J. J. (2007). Transcriptional regulation of deoxynivalenol-induced IL-8 expression in human monocytes. Toxicol. Sci. 99(2), 502-511.


Guarisco, J.A., Hall, J.O., and R.A. Coulombe, Jr. (2007) Butylated hydroxytoluene reduces aflatoxin B1 bioavailability and hepatic adduct formation in turkeys. In Poisonous Plants: Global Research and Solutions (K. Panter, T. Wierenga, J. Phister, eds.) CAB International, London. pp. 197-202.


Heemstra, J. M., Kerrigan, S. A., Doerge, D. R., Helferich, W. G. and Boulanger, W. A. (2006) Total synthesis of (S)-equol. Org. Lett.Vol. 8, No. 24, 5441-5443.


Hill, N.S., Schwarz, L.S., Dahleen, L.S., Neate, S.M., Horsley, R., Glenn, A.E., and O'Donnell, K. (2006). ELISA analysis for Fusarium in barley: Development of methodology and field assessment. Crop Science 46: 2636-2642.


Hockings J.K., Thorne P.A., Kemp M.Q., Morgan S.S., Selmin O. and Romagnolo D.F. (2006) The Ligand Status of the Aromatic Hydrocarbon Receptor Modulates Transcriptional Activation of BRCA-1 Promoter by Estrogen. Cancer Research, 66:1-9.


Hsu JC, Dev A, Wing A, Brew CT, Bjeldanes LF and Firestone GL. (2006) Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein. Biochem Pharmacol. 72(12):1714-23.


Islam, Z., Amuzie, C. J., Harkema, J. R., and Pestka, J. J. (2007). Neurotoxicity and inflammation in the nasal airways of mice exposed to the macrocyclic trichothecene mycotoxin roridin a: kinetics and potentiation by bacterial lipopolysaccharide coexposure. Toxicol. Sci. 98(2), 526-541.


Islam, Z., Harkema, J. R., and Pestka, J. J. (2006). Satratoxin G from the black mold Stachybotrys chartarum evokes olfactory sensory neuron loss and inflammation in the murine nose and brain. Environ. Health Perspect. 114(7), 1099-1107.


Ju, Y. H., Fultz J, Allred K.F., Doerge D.R., and Helferich, W.G. (2006) Effects Of Dietary Daidzein And Its Metabolite, Equol, At Physiological Concentrations On The Growth Of Estrogen-Dependent Human Breast Cancer (MCF-7) Tumor Implanted In Ovariectomized Athymic Mice. Carcinogenesis 27(4):856-63.


Ju, Y.H., Allred, K.F., Allred, C.D., and Helferich, W.G., (2006) Genistein Stimulates Growth of Human Breast Cancer Cells in a Novel, Postmenopausal Animal Model, with Low Plasma Estradiol Concentrations. Carcinogenesis 27(6):1292-9


Ju, Y.H., Clausen, L.M., Almada, A.L., and Helferich, W.G. (2004) Beta$-sitosterol, $Beta-sitosterol glucoside, and a mixture of $Beta- sitosterol and $-sitosterol glucoside modulate the growth of estrogen-responsive breast cancer cells in vitro and in ovariectomized athymic mice. J. Nutr. 134(5):1145-51.


Juneja, V. K. and Friedman, M. (2007) Carvacrol, cinnamaldehyde, oregano oil, and thymol inhibit Clostridium perfringens spore germination and outgrowth in ground turkey during chilling. J. Food Protection. 70 (1): 218-222.


Juneja, V. K., Bari, M. L., Inatsu, Y., Kawamoto, S., and Friedman, M. (2007) Control of Clostridium perfringens spores by green tea leaf extracts during cooling of cooked ground beef, chicken, and pork. J. Food Protection 70 (6): 1429-1433.


Kemp, M.Q., Thorne, P.A., Liu, W., Kane, M.D., Selmin, O. and Romagnolo, D.F. (2006) Expression Profiles Induced by Polycyclic Aromatic Hydrocarbons: The Transferrin Receptor as an Aromatic Hydrocarbon Receptor-inducible Biomarker of Exposure. Environmental Molecular Mutagenesis 47:518-526.


Kirui, G. K., Misra, A. K., Olanya, O. M., Friedman, M., El-Bedewy, R., and Ewell, P. T. (2007) Glycoalkaloid content of some superior potato (Solanum tuberosum L) clones and commercial cultivars. Archiv. Phytopathology and Plant Protection. Online (1): 1 - 11. 2007.


Kozukue, N., Park, M.-S., Choi, S.-H., Lee, S.-U., Ohnishi-Kameyama, M., Levin, C. E., and Friedman, M. (2007) Kinetics of light-induced cis-trans isomerization of four piperines and their levels in ground black peppers as determined by HPLC and LC/MS. J. Agric. Food Chem. 55 (17): 7131-7139.


Li, M., Harkema, J. R., Cuff, C. F., and Pestka, J. J. (2007). Deoxynivalenol exacerbates viral bronchopneumonia induced by respiratory reovirus infection. Toxicol. Sci. 95(2), 412-426.


Li, M., Harkema, J. R., Islam, Z., Cuff, C. F., and Pestka, J. J. (2006). T-2 toxin impairs murine immune response to respiratory reovirus and exacerbates viral bronchiolitis. Toxicol. Appl. Pharmacol. 217(1), 76-85.


Mbandi, E., and Pestka, J. J. (2006). Deoxynivalenol and satratoxin G potentiate proinflammatory cytokine and macrophage inhibitory protein 2 induction by Listeria and Salmonella in the macrophage. J. Food Prot. 69(6), 1334-1339.


Morgavi, D.P. and Riley, R.T. (2007) Fusarium and their toxins: Mycology, occurrence, toxicity, control and economic impact. Animal Feed Science and Technology 137: 199-200.


Morgavi, D.P. and Riley, R.T. (2007) An historical overview of field disease outbreaks known or suspected to be caused by consumption of feeds contaminated with Fusarium toxins. Animal Feed Science and Technology 137: 201-212.


Muthyala, R.S., Ju, Y.H., Sheng, S., Williams, L.D., Doerge, D.R., Katzenellenbogen, B.S., Helferich, W.G., and Katzenellenbogen, J.A. (2004) Equol, a natural estrogenic metabolite from soy isoflavones: convenient synthesis and resolution of R- and S-equol and their biological activity through the estrogen receptors alpha and beta. Bioorganic & Medicinal Chemistry 12(6): 1559-567.



Nerurkar, P.V., Pearson, L., Efird, J., Adeli, K., Theriault, A.. and Nerurkar, V.R. (2005) Inhibition of microsomal triglyceride transfer protein (MTP) gene expression and ApoB secretion by bitter melon in HepG2 Cells. J. Nutr. 135: 702-706.



Nerurkar, P.V., Lee, Y.K., Linden, E.H., Lim, S., Pearson, L., Frank, J. and Nerurkar, V.R. (2006) Lipid lowering effects of Momordica charantia (bitter melon) on cellular lipids and apolipoproteins in protease inhibitor-treated human hepatoma cells. Br J Pharmacol. 148(8):1156-64.



Putt, K.S., Chen, G.W., Pearson, J.M., Sandhorst, J.S., Hoagland, M.S., Kwon, J.T., Hwang, S.K., Jin, H., Churchwell, M.I., Cho, M.H., Doerge, D.R., Helferich, W.G. and Hergenrother, P.J. (2006) Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nat Chem Biol. 2, 10, 543-550.


Reed, K.M., Mendoza, K.M. and R. A. Coulombe, Jr. (2007). Structure and genetic mapping of the Cytochrome P4501A5 gene in the turkey (Meleagris gallopavo). Cytogenetics and Genome Research 116: 104-109


Rojas-Graü, M. A., Olsen, C., Avena-Bustillos, R. J., Friedman, M., Henika, P. R., Martin-Belloso, O., and McHugh, T. H. (2007) Effects of plant essential oils and oil compounds on physicochemical and antimicrobial properties of alginate-apple puree edible film. J. Food Engineering 81 (3): 634-641.


Romagnolo, D.F., S.C. Degner, M.Q. Kemp, J.K. Hockings, and O. Selmin. (2006) Role of dietary xenobiotics-gene interactions in carcinogenesis: protective effects of nutritional factors. Current Nutrition Review&Food Science. 2:205-214.


Seiferlein, M., Humpf, H.-U., Voss, K. A., Cameron Sullards, M., Allegood, J. C., Wang, E. and Merrill, Jr., A. H. 2007. Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase for form cytotoxic N-acyl-metabolites. Molecular Nutrition and Food Research. 51: 1120-1130.


Selvaraj V, Zakroczymski MA, Naaz A, Mukai M, Ju YH, Doerge DR, Katzenellenbogen JA, Helferich WG, Cooke PS (2004) Estrogenicity of the isoflavone metabolite equol on reproductive and non-reproductive organs in mice. Biology of Reproduction 71:966-972.


Shi, Y., and Pestka, J. J. (2006). Attenuation of mycotoxin-induced IgA nephropathy by eicosapentaenoic acid in the mouse: dose response and relation to IL-6 expression. J. Nutr. Biochem. 17(10), 697-706.


Sundar SN, Kerekatte V, Equinozio CN, Doan VB, Bjeldanes LF and Firestone GL. (2006) Indole-3-carbinol selectively uncouples expression and activity of estrogen receptor subtypes in human breast cancer cells. Mol Endocrinol. 20(12):3070-82.


Suzuki, H., Riley, R.T. and Sharma, R.P. (2007) Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase. Toxicology 229: 42-53.


Tilton, S.C., Hendricks, J.D., Orner, G.A., Pereira, C.B., Bailey, G.S., and Williams, D.E. (2007) Gene expression analysis during tumor enhancement by the dietary phytochemical, 3,3-diindolylmethane, in rainbow trout. Carcinogenesis 28:1589-1598.


Van Vleet, T.R., Watterson, T.L., Klein, P.J., and R.A. Coulombe, Jr. (2006) Aflatoxin B1 alters the expression of p53 in cytochrome P450-expressing human lung cells. Toxicological Sciences. 89 (2), 399-407.


Voss, K.A., Riley, R.T., Gelineau van Waes, J. (2007) Toxicity of fumonisins, mycotoxins from Fusarium verticillioides. In: Wilson, C.L., Editor. Microbial Food Contamination, 2nd Edition. Boca Raton, FL: CRC Press LLC, pp. 107-126.


Voss, K.A., Smith, G.W. and Haschek, W. M. (2007) Fumonisins: toxicokinetics, mechanism of action and toxicity. Animal Feed Science and Technology 137: 299-325.


Watterson, T.L., Sorenson, J., Martin, R., and R.A. Coulombe, Jr. (2007) Effects of PM2.5 Collected from Cache Valley Utah on Genes Associated with the Inflammatory Response in Human Lung Cells. J. Toxicol. Environ. Health 70:1731-1734.


Williams, L.D., Glenn, A.E., Bacon, C.W., Zimeri, A.M., Smith, M.A. and Riley, R.T. 2007. Fumonisin disruption of ceramide biosynthesis in maize roots and the effects on plant development and Fusarium verticillioides-induced seedling disease. J. Agric. Food Chem. 55:2937-2946.


Xue L, Pestka JJ, Li M, Firestone GL and Bjeldanes LF. (2007) 3,3'-Diindolylmethane stimulates murine immune function in vitro and in vivo. J Nutr Biochem. 2007 Aug 16; [Epub ahead of print]


Yip, S.S.M. and R.A. Coulombe, Jr. (2006) Molecular cloning and expression of a novel cytochrome P450 from turkey liver with aflatoxin B1 metabolizing activity. Chem. Res. Toxicol. 19:30-37.

11/17/2008

PUBLICATIONS

Ahn, K.C., Zhao, B., Chen, J., Cherednichenko, G., Sanmarti, E., Denison, M.S., Lasley, B., Pessah, I.N., Kultz, D., Chang, D.P., Gee, S.J. and Hammock, B.D. (2008) In vitro biological activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens, Environ. Health Perspect. 116: 1203-1210.

Amuzie, C. J., Harkema, J. R., and Pestka, J. J. (2008) Tissue distribution and proinflammatory cytokine induction by the trichothecene deoxynivalenol in the mouse: comparison of nasal vs. oral exposure. Toxicology 248: 39-44.

Bae, H. K., and Pestka, J. J. (2008) Deoxynivalenol induces p38 interaction with the ribosome in monocytes and macrophages. Toxicol Sci 105: 59-66.

Beli, E., Li, M., Cuff, C., and Pestka, J. J. (2008) Docosahexaenoic acid-enriched fish oil consumption modulates immunoglobulin responses to and clearance of enteric reovirus infection in mice. J Nutr. 138: 813-819.

Bohonowych, J.E. and Denison, M.S. (2007) Persistent binding of ligands to the aryl hydrocarbon receptor, Toxicol. Sci. 98: 99-110.


Brown, D. J., Orelien, J., Gordo, J. D., Chu, A. C., Chu, M. D., Murata, H. J., Kayama, F., Denison, M. S. and Clark, G. C. (2007) Mathematical model developed for environmental samples: prediction of GC/MS dioxin TEQ from XDS-CALUX bioassay data, Environ. Toxicol. Chem. 41: 4354-4360.

Burns, T.D., Snook, M.E., Riley, R.T. and Voss, K.A. (2008) Fumonisin concentrations and in vivo toxicity of nixtamalized Fusarium verticillioides culture material: Evidence for fumonisin-matrix interactions. Food Chem Toxicol 46: 2841-2848.

Carter, O., Dashwood, R.H., Wang, R., Dashwood, W.M., Orner, G.A., Fisher, K.A., Löhr, C.V., Pereira, C.B., Bailey, G.S. and Williams, D.E. (2007) Comparison of White Tea, Green Tea, Epigallocatechin-3-Gallate and Caffeine as Inhibitors of PhIP-Induced Colonic Aberrant Crypts. Nutr Cancer 58: 60-65.

Castro, D.J., Löhr, C., Fischer, K., Waters, K., Webb-Robertson, B.-J., Dashwood, D.H., Bailey, G.S. and Williams, D.E. (2008) Identifying Efficacious Approaches to Chemoprevention with Chlorophyllin, Purified Chlorophylls and Freeze-Dried Spinach in a Mouse Model of Transplacental Carcinogenesis. Carcinogenesis 30: 315-320.

Castro, D.J., Baird, W.M., Pereira, C., Giovanini, J., Löhr, C., Fischer, K., Yu, Z., Gonzalez, F.J., Krueger, S.K. and Williams, D.E. (2008) Fetal Cyp1b1 in Mice and Transplacental Carcinogenesis From Maternal Exposure to Dibenzo[a,l]pyrene. Cancer Prev Res 1: 128-134.

Castro, D.J., Yu., Z., Löhr, C.V., Pereira, C.B., Giovanini, J., Fischer, K.A., Orner, G.A., Dashwood, R.H., and Williams, D.E. (2008) Chemoprevention of Dibenzo[a,l]pyrene Transplacental Carcinogenesis in Mice Born to Mothers Administered Green Tea: Primary Role of Caffeine. Carcinogenesis 29: 1581-1586.

Castro, D.J., Yu, Z., Dashwood, R.H., Bailey, G.S., Baird, W.M. and Williams, D.E. (2008) A Model for the Study of Maternal Dietary Inhibition of Transplacental Carcinogenesis. In Recent Advances in Carcinogenesis, (R.M. Mohan, Ed.).

Castro, D.J., Löhr, C.V., Fischer, K.A, Pereira, C. and Williams, D.E. (2008) Lymphoma and Lung Cancer in Offspring Born to Pregnant Mice Dosed with Dibenzo[a,l]pyrene: The Importance of In Utero Versus Lactational Exposure. Toxicol Appl Pharmacol 233: 454-458.

Chang, E.C., Charn, T.H., Park, S.H., Helferich, W.G., Komm, B., Katzenellenbogen, J.A. and Katzenellenbogen, B.S. (2008). Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding. Mol Endocrinol 22: 1032-1043.


Coulombe, R.A. and Yip, S.M. (2007) Heterologous expression of a cytochrome P450 from turkey liver that activates aflatoxin B1. In Poisonous Plants: Global Research and Solutions (K. Panter, T. Wierenga, J. Phister, eds.) CAB International, London. pp. 82-88.

Du, W.-X., Olsen, C.E., Avena-Bustillos, R.J., McHugh, T.H., Levin, C.E. and Friedman, M. (2008) Antibacterial activity against E. coli O157:H7, physical properties, and storage stability of novel carvacrol-containing edible tomato films. J Food Sci 73: M378-M383.


Du, W.-X., Olsen, C.W., Avena-Bustillos, R.J., McHugh, T.H., Levin, C.E. and Friedman, M. (2008) Storage stability and antibacterial activity against Escherichia coli O157:H7 of carvacrol in edible apple films made by two different casting methods. J Agric Food Chem 56: 3082-3088.

Dvorak, N., Riley, R.T., Harris M. and McGregor, J.A. (2008) Fumonisin mycotoxin contamination of corn-based foods consumed by potentially pregnant women in Southern California. Journal Reprod Mede 53: 672-676.

Friedman, M. (2008) Dietary significance of processing-induced lysinoalanine in food. In "Process-Induced Food Toxicants: Occurrence, Formation, Mitigation, and Health Risks", Stadler, R.H. and Lineback, D.R., Eds., John Wiley & Sons, New York, Chpt. 6.1, pp. 477-510. 2009.

Friedman, M. (2008) Dietary significance of processing-induced D-amino acids. In "Process-Induced Food Toxicants: Occurrence, Formation, Mitigation, and Health Risks", Stadler, R.H. and Lineback, D.R., Eds., John Wiley & Sons, New York, Chpt. 6.2, pp. 511-537. 2009.


Friedman, M. and Levin, C.E. (2008) Review of methods for the reduction of dietary content and toxicity of acrylamide. J Agric Food Chem 56: 6113-6140.

Friedman, M., C. E. Levin, C.E., Lee, S.-U., Lee, J.-S., Ohnisi-Kameyama, M. and Kozukue, N. (2008) Analysis by HPLC and LC/MS of pungent piperamides in commercial black, white, green, and red whole and ground peppercorns. J Agric Food Chem 56: 3028-3036.

Glenn, A.E., Zitomer, N.C., Zimeri, A.M. , Williams, L.D., Riley, R.T. and Proctor, R.H. (2008) Transformation-mediated complementation of a FUM gene cluster deletion in Fusarium verticillioides restores both fumonisin production and pathogenicity on maize seedlings. Molec Plant-Microbe Interact 21: 87-97.

Gray, J. S., Bae, H. K., Li, J. C., Lau, A. S., and Pestka, J. J. (2008) Double-stranded RNA-activated protein kinase mediates induction of interleukin-8 expression by deoxynivalenol, Shiga toxin 1, and ricin in monocytes. Toxicol.Sci 105, 322-330.

Guarisco, J.A., Hall, J.O. and Coulombe, R.A., Jr. (2007) Butylated hydroxytoluene reduces aflatoxin B1 bioavailability and hepatic adduct formation in turkeys. In Poisonous Plants: Global Research and Solutions (K. Panter, T. Wierenga, J. Phister, eds.) CAB International, London. pp. 197-202.

Guarisco, J.A., Hall, J.O. and Coulombe, R.A., Jr. (2008) Butylated hydroxytoluene chemoprevention of aflatoxicosis - effects on aflatoxin B1 bioavailability, hepatic DNA adduct formation, and biliary excretion. Food Chem Toxicol 46: 3727-3723.

Guarisco, J.A., Hall, J.O. and Coulombe, R.A., Jr. (2008) Mechanisms of butylated hydroxytoluene chemoprevention of aflatoxicosis - inhibition of aflatoxin B1 metabolism. Toxicol Appl Pharmacol 227: 339-346.

Heemstra, J. M., Kerrigan, S. A., Doerge, D. R., Helferich, W. G. and Boulanger, W. A. (2007). Total synthesis of (S)-equol. Org Lett 8:5441-5443.

Helferich, W.G., Andrade, J.E. and Hoagland, M.S. (2008). Phytoestrogens and breast cancer: a complex story. Inflammopharmacology : 219-226.

Higdon, J.V., Delage, B., Williams, D.E. and Dashwood, R.H. (2007) Cruciferous Vegetables and Human Cancer Risk: Epidemiologic Evidence and Mechanistic Basis. Pharmacol Res 55: 224-236.

Hu, W., Sorrentino, C., Denison, M.S., Kolaja, K. and Fielden, M. (2007) Induction of Cyp1a1 is a Non-Specific Biomarker of Aryl Hydrocarbon Receptor Activation: Results of Large Scale Screening of Pharmaceuticals and Toxicants In Vivo and In Vitro, Molec. Pharmacol. 71: 1475-1486.

Im, W.I., Suh, B.-S., Lee, S.-U., Kozukue, N., Ohnisi-Kameyama, M., Levin, C.E. and Friedman, M. (2008) Analysis of phenolic compounds by high-performance liquid chromatography and liquid chromatography/mass spectrometry in potato plant flowers, leaves, stems, and tubers and in processed potatoes. J Agric Food Chem 56:3341-3349.

Islam, Z., Hegg, C. C., Bae, H. K., and Pestka, J. J. (2008) Satratoxin G-induced apoptosis in PC-12 neuronal cells is mediated by PKR and caspase independent. Toxicol.Sci 105, 142-152.

Jiang, X., Patterson, N.M., Ling, Y., Xie, J. Helferich, W.G. and Shapiro, D.J. (2008). Low Concentrations of the Soy Phytoestrogen Genistein Induce Proteinase Inhibitor 9 and Block Killing of Breast Cancer Cells by Immune Cells. Endocrinology 149: 5366-5373.

Ju, Y.H., Doerge, D. and Helferich, W.G. (2008). A dietary supplement for female sexual dysfunction, Avlimil, stimulates the growth of estrogen-dependent breast tumors (MCF-7) implanted in ovariectomized athymic nude mice. Food Chem Toxicol 46: 310-320.

Ju, Y.H., Doerge, D.R., Woodling, K.A., Hartman, J.A., Kwak, J. and Helferich, W.G. (2008). Dietary Genistein Negates the Inhibitory Effect of Letrozole On The Growth Of Aromatase-expressing Estrogen-Dependent Human Breast Cancer Cells (MCF-7Ca) In vivo. Carcinogenesis 29: 2162-2168.

Juneja, V.K. and Friedman, M. (2008) Carvacrol and cinnamaldehyde facilitate thermal destruction of Escherichia coli O157:H7 in raw ground beef. J Food Prot 71: 1604-1611.

Lee, S.U., Lee, J.H., Choi, S.H., Lee, J.S., Ohnisi-Kameyama, M., Kozukue, N., Levin, C.E. and Friedman, M. (2008) Flavonoid content in fresh, home-processed, and light-exposed onions and in dehydrated commercial onion products. J Agric Food Chem 56: 8541-8548.

Li, M., and Pestka, J. J. (2008). Comparative induction of 28S ribosomal RNA cleavage by ricin and the trichothecenes deoxynivalenol and T-2 toxin in the macrophage. Toxicol.Sci 105, 67-78.

Lim, S., Dragull, K., Tang, C.S., Bittenbender, S. and Nerurkar, P.V. (2007) Effects of Kava Alkaloid, Pipermethystine (PM), and Kavalactones on Oxidative Stress and Hepatic Cytochrome P450 in F344 Rats. Toxicol Sci 97: 214-221.


Loniewski, K., Shi, Y., Pestka, J., and Parameswaran, N. (2008) Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages. Mol Immunol. 45, 2312-2322.

Mersereau, J.E., Levy, N., Staub, R.E., Baggett, S., Zogric, T., Chow, S., Ricke, W.A., Tagliaferri M., Cohen, I., Bjeldanes, L.F. and Leitman, D.C. (2008) Liquiritigenin is a plant-derived highly selective estrogen receptor beta agonist. Mol Cell Endocrinol 283: 49-57.


Mottram, D.S. and Friedman, M. (2008) Preface - Symposium on the Chemistry and Toxicology of Acrylamide. J Agric Food Chem 56: 5983.

Nerurkar, P.V., Lee, Y.-K., Motosue, M., Adeli, K. and Nerurkar, V.R. (2008) Momordica charantia (bitter melon) reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions. British J Nutri 100: 751-759.


Nerurkar, P.V. and Nerurkar, V.R. (2008) Is Sirt1 the magic target for diabetes? Cell Science Reviews, 2008; 4: 50-56.

Nerurkar, P.V. (2008) Cancer and Sirt1 regulation Cell Science Reviews, 4: 82-96.

Nording, M., Persson, Y., Spinnel, E., Baston, D., Denison, M.S. and Haglund, P. (2007) Analysis of dioxins in contaminated soils using CALUX and CAFLUX bioassays, an immunoassay and gas chromatography - high resolution mass spectrometry, Environ. Toxicol. Chem. 26: 1122-1129.

Pestka, J. J., Yike, I., Dearborn, D. G., Ward, M. D., and Harkema, J. R. (2008). Stachybotrys chartarum, trichothecene mycotoxins, and damp building-related illness: new insights into a public health enigma. Toxicol.Sci 104, 4-26.

Pestka, J. J., and Amuzie, C. J. (2008) Tissue distribution and proinflammatory cytokine gene expression following acute oral exposure to deoxynivalenol: comparison of weanling and adult mice. Food Chem Toxicol. 46, 2826-2831.

Pestka, J. J. (2008) Mechanisms of deoxynivalenol-induced gene expression and apoptosis. Food Addit.Contam 1-13.

Pestka, J. J., Islam, Z., and Amuzie, C. J. (2008) Immunochemical assessment of deoxynivalenol tissue distribution following oral exposure in the mouse. Toxicol.Lett 178: 83-87.

Putt, K.S., Chen, G.W., Pearson, J.M., Sandhorst, J.S., Hoagland, M.S., Kwon, J.T., Hwang, S.K., Jin, H., Churchwell, M.I., Cho, M.H., Doerge, D.R., Helferich, W.G. and Hergenrother, P.J. (2007) Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nat Chem Biol 10: 543-550.

Ravishankar, S., Zhu, L.,Law, B., Joens, L. and Friedman, M. (2008) Plant-derived compounds inactivate antibiotic-resistant Campylobacter jejuni strains. J Food Prot 71: 1145-1149.

Reed, K.M., Mendoza, K.M. and Coulombe, R.A., Jr. (2007). Structure and genetic mapping of the Cytochrome P4501A5 gene in the turkey (Meleagris gallopavo). Cytogenetics and Genome Research 116: 104-109.

Riby, J.E., Firestone, G.L. and Bjeldanes, L.F. (2008) 3,3'-Diindolylmethane reduces levels of HIF-1alpha and HIF-1 activity in hypoxic cultured human cancer cells. Biochem Pharmacol 75: 1858-67.

Rochester, J.R., Klasing, K.C., Stevenson, L., Denison, M.S., Berry, W. and Millam, J.r. (2008) Dietary red clover (Trifolium pratense) induces oviduct growth and decreases ovary and testes growth in Japanese quail chick, Reprod. Toxicol. 27: 63-71.

Shi, Y., and Pestka, J. J. (2008). Mechanisms for suppression of interleukin-6 expression in peritoneal macrophages from docosahexaenoic acid-fed mice. J Nutr Biochem in press.

Simonich, M.T., Egner, P.A., Robuck, B.D., Orner, O., Jubert, C., Pereira, C., Groopman, J.D., Kensler, T.W., Dashwood, R.H., Williams, D.E. and Bailey, G.S. (2007) Natural Chlorophyll Inhibits Aflatoxin B1 Induced Multi-Organ Carcinogenesis in the Rat. Carcinogenesis 28: 1294-1302.

Simonich, M.T., McQuistan, T., Jubert, C., Pereira, C., Hendricks, J.D., Schimerlik, M., Zhu, B., Dashwood, R., Williams, D.E. and Bailey, G.S. (2008) Low-Dose Dietary Chlorophyll Inhibits Multi-Organ Carcinogenesis in the Rainbow Trout. Food Chem Toxicol 46: 1014-1024.

Sirk, T.W., Brown, E.F., Sum, A.K. and Friedman, M. (2008) Molecular dynamics study on the biophysical interactions of seven green tea catechins with lipid bilayers of cell membranes. J. Agric. Food Chem 56: 7750-7758.

Snee, L.S., Nerurkar, V.R., Dooley, D., Efird, J., Shovic, A., Nerurkar, P.V. (2008) Feasibility study to increase palatability and consumption of Momordica charantia (Bitter Melon). Appetite, submitted.

Tilton, S.C., Hendricks, J.D., Orner, G.A., Pereira, C.B., Bailey, G.S. and Williams, D.E. (2007) Gene Expression Analysis During Tumor Enhancement by the Dietary Phytochemical and Supplement, 3,3-Diindolylmethane, in Rainbow Trout. Carcinogenesis, 28: 1589-1598.

Tilton, S.C., Orner, G.A., Benninghoff, A.D., Carpenter, H.M., Hendricks, J.D., Pereira, C.B. and Williams, D.E. (2008) Genomic Profiling Reveals an Alternate Mechanism for Hepatic Tumor Promotion by Perfluorooctanoic Acid in Rainbow Trout. Environ Hlth Perspect 116: 1047-1055.

Torres, O.A., Palencia, E., Lopez de Pratdesaba, L., Grajeda, R, Fuentes, M., Speer, M., Merrill, A.H., Jr., ODonnell, K., Bacon, C.W., Glenn, A.E. and Riley, R.T. (2007) Estimated fumonisin exposure in Guatemala is greatest in consumers of lowland maize. J Nutrition 137: 2723-2729.

Voss, K.A., Riley, R.T. and Gelineau van-Waes, J.B. (2007) Fetotoxicity and neural tube defects in CD1 mice exposed to the mycotoxin fumonisin B1. Mycotoxins 57: 67-72.

Wang, R., Dashwood, W.M., Löhr, C.V., Fisher, K.A., Pereira, C.B., Louderback, M., Nakagama, H., Bailey, G.S., Williams, D.E. and Dashwood, R.H. (2008) Protective Versus Promotional Effects of White Tea and Caffeine on PhIP-Induced Tumorigenesis and b catenin expression in the Rat. Carcinogenesis 29: 834-839.


Wang, R., Dashwood, W.-M., Löhr, C.V., Fischer, K.A., Nakagama, H., Williams, D.E. and Dashwood, R.H. (2008) Beta-Catenin is Strongly Elevated in Rat Colonic Epithelium Following Short-Term Intermittent Treatment with 2-Amino-1-Methyl-6-Phenyimidazo[4,5-b]Pyridine (PhIP) and a High-Fat Diet. Cancer Sci 99: 1754-1759.

Wang, V.C., Sable, H.J., Ju, Y.H., Allred, C.D., Helferich, W.G., Korol, D.L. and Schantz, S.L. (2008). Effects of chronic estradiol treatment on delayed spatial alternation and differential reinforcement of low rates of responding. Behav Neurosci 122: 794-804.

Watterson, T.L., Sorenson, J., Martin, R., and Coulombe, R.A., Jr. (2007). Effects of PM2.5 Collected from Cache Valley Utah on Genes Associated with the Inflammatory Response in Human Lung Cells. J Toxicol Environ Health 70: 1731-1734.

Wong, S.Y., Grant, I.R., Friedman, M., Elliott, C.T. and Situ, C. (2008) Antibacterial activities of naturally occurring compounds against Mycobacterium avium subsp. paratuberculosis. Appl Environ Microbiol 74: 5986-5990.

Xue, L., Pestka, J. J., Li, M., Firestone, G. L., and Bjeldanes, L. F. (2008). 3,3'-Diindolylmethane stimulates murine immune function in vitro and in vivo. J Nutr.Biochem 19, 336-344.

Zitomer, N. C., Glenn, A. E., Bacon, C.W. and Riley, R.T. (2008) A single extraction method for the analysis by liquid chromatography/tandem mass spectrometry of fumonisins and biomarkers of disrupted sphingolipid metabolism in tissues of maize seedlings. Anal Bioanal Chem 391: 2257-2263.

11/11/1111

03/02/2011

Wu QX, Crews MS, Draskovic M, Sohn J, Johnson TA, Tenney K, Valeriote FA, Yao XJ, Bjeldanes LF, Crews P. Azonazine, a novel dipeptide from a Hawaiian marine sediment-derived fungus, Aspergillus insulicola.Org Lett. 2010 Sep 24. [Epub ahead of print] PMID: 20866076

Nguyen HH, Lavrenov SN, Sundar SN, Nguyen DH, Tseng M, Marconett CN, Kung J, Staub RE, Preobrazhenskaya MN, Bjeldanes LF, Firestone GL.1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells. Chem Biol Interact. 2010 Aug 5;186(3):255-66. Epub 2010 Jun 2. PMID: 20570586

Aronchik I, Bjeldanes LF, Firestone GL. Direct inhibition of elastase activity by indole-3-carbinol triggers a CD40-TRAF regulatory cascade that disrupts NF-kappaB transcriptional activity in human breast cancer cells. Cancer Res. 2010 Jun 15;70(12):4961-71. Epub 2010 Jun 8. PMID: 20530686

Vivar OI, Saunier EF, Leitman DC, Firestone GL, Bjeldanes LF. Selective activation of estrogen receptor-beta target genes by 3,3'-diindolylmethane.Endocrinology. 2010 Apr;151(4):1662-7. Epub 2010 Feb 16. PMID: 20160136

Marconett CN, Sundar SN, Poindexter KM, Stueve TR, Bjeldanes LF, Firestone GL. Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER)alpha protein degradation in breast cancer cells disrupting an ERalpha-GATA3 transcriptional cross-regulatory loop. Mol Biol Cell. 2010 Apr 1;21(7):1166-77. Epub 2010 Feb 3. PMID: 20130088

Iwaniec, U.T., Dube, M.G., Boghossian, S., Song, H., Helferich, W.G., Turner, R.T., and Kalra, S.P., (2009). Body mass influences cortical bone mass independent of leptin signaling. Bone. 44(3): p. 404-12. PMID: 19095090 NIHMSID: NIHMSID98145

Legette, L.L., Martin, B.R., Shahnazari, M., Lee, W.H., Helferich, W.G., Qian, J., Waters, D.J., Arabshahi, A., Barnes, S., Welch, J., Bostwick, D.G., and Weaver, C.M., (2009). Supplemental dietary racemic equol has modest benefits to bone but has mild uterotropic activity in ovariectomized rats. J Nutr. 139(10):1908-13. PMID: 19710157 PMCID: PMC2744611

Zhang, Y., Li, Q.,Wan, HY, Helferich,WG, Wong, MS. (2009). Genistein and a Soy Extract Differentially Affect Three-Dimensional Bone Parameters and Bone-Specific Gene Expression in Ovariectomized Mice. J. Nutr., Dec 2009; 139: 2230 - 2236. PMID: 19793844

Neese, S.L., Wang, V.C., Doerge, D.R., Woodling, K.A., Andrade, J.E., Helferich, W.G., Korol, D.L., and Schantz, S.L., (2010). Impact of dietary genistein and aging on executive function in rats. Neurotoxicol Teratol. 32(2): p. 200-211. PMID: 19945528

Hsu, A., Bray, T.M., Helferich, W.G., Doerge, D.R., and Ho, E., (2010). Differential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cells. Exp. Biol. Med. 2010;235:90-7. PMID: 20404023

Andrade, J. E., Twaddle, N.C., Helferich, W.G. and Doerge, D.R., (2010). Absolute Bioavailability of Isoflavones from Soy Protein Isolate-Containing Food in Female Balb/c Mice. J Agric Food Chem;58:4529-36. PMID: 20225898

Cimafranca, M.A., Davila, J., Ekman, G.C., Andrews, R.N., Neese, S.L., Peretz, J., Woodling, K.A., Helferich, W.G., Sarkar, J., Flaws, J.A., Schantz, S.L., Doerge, D.R., and Cooke, P.S. (2010). Acute and chronic effects of oral genistein administration in neonatal mice. Biol Reprod. Biol Reprod 2010;83:114-21. PMID: 20357267

Hilakivi-Clarke, L. Andrade, J.E., and Helferich. W.G. (2010). Is Soy Consumption good or bad for the breast? J. of Nutrition. 140(12):2326S-34S. Epub 2010 Oct 27. PMID: 20980638 PMCID: PMC2981011 Yang, X., Belosay, A., Du, M., Hartman, J.A., Jackson, M., Fan, T.M., Turner, T.R., Iwaniec, U.T., and Helferich, W.G. (2011). Evaluating Breast Cancer Metastasis Using Bioluminescence Imaging and Murine Models. Submitted

De Assis, S., Warri, A. , Benitez, C. , Helferich, W.G.,and Hilakivi-Clarke, L.A., (2011). Protective effects of prepubertal genistein exposure on mammary tumorigenesis are dependent on BRCA1 expression. Cancer Prevention Research. In Press.

Morisseau, C., Merzlikin, O. Lin, A., He, G. Feng, W., Padilla, I., Denison, M.S., Pessah, I.N. and Hammock, B.H. (2009) Toxicology in the fast lane: Application of high-throughput bioassays to detect modulation of key enzymes and receptors, Environ. Health Perspect., 117, 1867-1872. PMC2799460

Petko, P.I., Rowlands, J.C., Budinsky, R., Zhao, B., Denison, M.S. and Mekenyan, O. (2010) Mechanism based common reactivity pattern (COREPA) modeling of AhR binding affinity, SAR QSAR Environ. Res., 21, 187-214. PMID: 20373220

Zhao, B., Baston, D.S., Khan, E., Sorrentino, C. and Denison, M.S. (2010) Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds, Science China Chemistry (Science in China Series B) 53, 1010-1016.

Boitano, A.E., Wang, J., Romeo, R., Bouchez, L.C., Parker, AE., Sutton, S.E., Walker, J.R., Flaveny, C.A., Perdew, G.H., Denison, M.S., Schultz, P.G. and Cooke, M.P. (2010) Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells, Science, 329, 1345-1348. PMID 2068898

Zhao, B., DeGroot, D., Hayashi, A., He, G. and Denison, M.S. (2010) CH223191 is a ligand-selective antagonist of the Ah (dioxin) Receptor, Toxicol. Sci. 117, 393-403. PMID 20634293

Nerurkar P, Ray RB. Bitter melon: antagonist to cancer. Pharm Res. 2010 Jun;27(6):1049-53. Epub 2010 Mar 3. PMID: 20198408

Ray RB, Raychoudhuri A, Steele R, Nerurkar P. Bitter melon (Momordica charantia) extract inhibits breast cancer cell proliferation by modulating cell cycle regulatory genes and promotes apoptosis. Cancer Res. 2010 Mar 1;70(5):1925-31. Epub 2010 Feb 23. PMID: 20179194

Nerurkar PV*, Lee Y-K and Nerurkar VR. Y-K. Momordica charantia (bitter melon) inhibits primary human adipocyte differentiation by modulating adipogenic genes. BMC Complement Altern Med. 2010 10: 34-41. Epub 2010 July 01. PMCID: 2911406

Islam, Z., Shinozuka, J., Harkema, J.R., and Pestka, J.J. 2010. Purification and comparative neurotoxicity of the trichothecenes satratoxin G and roridin 12 from Stachybotrys chartarum. J. Toxicol. Environ. Health A., 116(2):433-40. PMC2808125.

Pestka, J.J. 2010. Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance. Arch. Toxicol. 84:663-679, PMID 20798930. Pestka, J.J. 2010. Deoxynivalenol-induced proinflammatory gene expression: Mechanisms and pathological sequelae. Toxins 2:1300-1317.

Lichtenstein, J.H., Molina, R.M., Donaghey, T.C., Amuzie, C.J., Pestka, J.J., Coull, B.A., and Brain, J.D. 2010. Pulmonary responses to Stachybotrys chartarum and its toxins: Mouse strain affects clearance and macrophage cytotoxicity. Toxicol. Sci. 116:113-121, PMID: 203855656.

Pestka, J.J. 2010. n-3 polyunsaturated fatty acids and autoimmune-mediated glomerulonephritis. Prostaglandins Leukot. Essent. Fatty Acids 82:251-258, PMC2885141.

Bae, H., Gray, J.S., Li, M., Vines, L., Kim, J., and Pestka, J.J. 2010. Hematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes. Toxicol. Sci. 115:444-452, PMC2902856.

Rakkestad, K.E., Skaar, I., Ansteinsson, V.E., Solhaug, A., Holme, J.A., Pestka, JJ., Sanuelsen, J.T., Dahlman, H.J., Hongslo, J.K., Becher, R. 2010. DNA damage and DNA damage responses in THP-1 monocytes after exposure to spores of either Stachybotrys chartarum or Aspergillus versicolor or to T-2 toxin. Toxicol. Sci. 115:1242-1251, PMC2902923.

Corps, K.N., Islam, Z., Pestka, J.J., and Harkema, J.R. 2010. Neurotoxic, inflammatory, and mucosecretory responses in the nasal airways of mice repeatedly exposed to the macrocyclic trichothecene mycotoxin roridin A: dose-response and persistence of injury. Toxicol. Pathol. 38:429-451, PMID: 20430879.

Amuzie, C.J., Islam, Z., Kim, J., Seo, J., and Pestka, J.J. 2010. Kinetics of satratoxin G tissue distribution and excretion following intranasal exposure in the mouse. Toxicol. Sci. 116:433-440, PMID: 20466779.

Maddox, J.F., Amuzie, C.J., Li, M., Newport, S.W., Sparkenbaugh, E., Cuff, C.F., Pestka, J.J., Cantor, G.H., Roth, R.A., and Ganey, P.E. 2010. Bacterial- and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity. J. Toxicol. Environ. Health A 73:58-73, PMID: 19953420.

Seo, J., Kim, J., and Pestka, J.J. Induction of Apoptosis in Primary Mesangial Cell by Deoxynivalenol. Toxicologist, 2010. Annual Meeting of the Society of Toxicology, Salt Lake City, UT, March 2010.

Kim, J., Seo, J., Hegg, C., and Pestka, J.J. Role of erk in oxidative stress-induced apoptosis in the op6 olfactory sensory neuron cell line. Toxicologist, 2010. Annual Meeting of the Society of Toxicology, Salt Lake City, UT, March 2010.

Shimada, N., Kim, J., Shinozuka, J., Hegg, C.C., and Pestka, J.J. Translation-dependent and independent mechanisms for satratoxin g-induced apoptosis. Toxicologist, 2010. Annual Meeting of the Society of Toxicology, Salt Lake City, UT, March 2010.

Flannery, B., Amuzie, C., Ulrich, A, and Pestka, J.J. Deoxynivalenol ingestion prevents and ameliorates diet-induced obesity in the mouse. Toxicologist, 2010. Annual Meeting of the Society of Toxicology, Salt Lake City, UT, March 2010.

He, K., Vines, L., and Pestka, J.J. Deoxynivalenol-induced modulation of microrna expression in raw 264.7 macrophagesa potential novel mechanism for translational inhibition. Toxicologist, 2010. Annual Meeting of the Society of Toxicology, Salt Lake City, UT, March 2010.

Vines, L.L., Langohr, I.M., and Pestka, J.J. Consumption of docosahexaenoic acid attenuates lupus nephritis-related gene expression and disease progression in NZBWF1 Mice. Toxicologist, 2010. Annual Meeting of the Society of Toxicology, Salt Lake City, UT, March 2010.

Hattori, K., Flannery, B., Amuzie, C., and Pestka, J.J. Modulation of body fat mass and lean weight in deoxynivalenol-induced body weight reduction in the obese mouse. Toxicologist, 2010. Annual Meeting of the Society of Toxicology, Salt Lake City, UT, March 2010.

O'Donnell, K., Gueidan, C., Sink, S., Johnston,P.R., Crous, P., Glenn, A., Riley, R., Zitomer, N., Colyer, P., Waalwijk, C., van der Lee, T., Moretti, A., Kang, S., Kim, H-S., Geiser, D.M., Juba, J., Baayen, R.P., Cromey, M.G., Bithel, S., Sutton, D.A., Skovgaard, K., Ploetz, R., Kistler, C., Elliott, M., Davis, M. (2009) A two-locus DNA sequence database for typing plant and human pathogens within the Fusarium oxysporum species complex. Fungal Genetics and Biology 46: 936948. 2009

Voss, K.A., Riley, R.T., Snook, M.E., Gelineau-van Waes, J. (2009) Comparing the reproductive and sphingolipid metabolic effects of fumonisin B1 and its alkaline hydrolysis product in LM/Bc mice: hydrolyzed fumonisin B1 did not cause neural tube defects. Toxicological Sciences 112: 459-67.

Zitomer NC, Jones, S., Bacon CW, Glenn AE, Baldwin, T. and Riley, R.T. (2010) Sphingoid bases and their 1-phosphates, but not fumonisins, are translocated from roots to aerial tissues of maize seedlings watered with fumonisins. Journal of Agricultural and Food Chemistry 58:7476-7481, 2010

Riley, R. T., Voss, K. A., Coulombe, R. A., Pestka, J. J. and Williams, D. E. (in press) Developing mechanism-based and exposure biomarkers for mycotoxins in animals. In De Saeger, S. (ed.) Determining Mycotoxins and Mycotoxigenic Fungi in Food and Feed, Ghent University, Woodhead Publishing Limited, Cambridge, UK. pp 245-275.

Riley, R.T., Voss, K.A., Zitomer, N., Glenn, A., Burns, T., Merrill, A.H. Jr., Torres, O. and Gelineau van Waes, J. (2010) Use of mechanism-based and exposure biomarkers to assess fumonisin toxicity in humans, animals and plants and efficacy of processing methods using mechanism-based bioassays. Proceedings of the VI Latin American Congress of Mycotoxicology and the II International Symposium on Algal and Fungal Toxins for Industry 2010. pp. 40-43 Universidad Nacional Autonoma de Mexico, Mexico City, 2010.

Papoutsis AJ, Lamore SD, Wondrak GT, Selmin OI, Romagnolo DF. Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells. J Nutr. 2010 Sep;140(9):1607-14. Epub 2010 Jul 14.

Romagnolo DF, Papoutsis AJ, Selmin O. Nutritional targeting of cyclooxygenase-2 for colon cancer prevention. Inflamm Allergy Drug Targets. 2010 Jul 1;9(3):181-91.

Milner J.A., and Romagnolo D.F. Nutrigenomics and Cancer Biology. In: Bioactive Food Components and Cancer, Humana Press/Springer. Eds. Milner and Romagnolo (2010).

Romagnolo D.F., Degner SC, and Selmin, O. Aryl Hydrocarbon Receptor-mediated Carcinogenesis and Modulation by Dietary Xenobiotic and Natural Ligands, In: Bioactive Food Components and Cancer, Humana Press/Springer. Eds. Milner and Romagnolo.(2010).

Swanson, H.I., Njar, V.C.O., Yu, Z., Castro, D.J., Gonzalez, F.J., Williams, D.E., Kong, A.-N.T., Waxman, D.J. and Scott, E.E. (2010) Symposium Article: Targeting Drug Metabolizing Enzymes for Effective Chemoprevention and Chemotherapy. Drug Metabol. Dispos 38:539-544.

Celius, T., Pansoy, A., Matthews, J., Okey, A.B., Henderson, M.C., Krueger, S.K., and Williams, D.E. (2010) Flavin-Containing Monooxygenase 3: Induction by 3-Methylcholanthrene and Complex Regulation by Xenobiotic Chemicals in Hepatoma Cells in Culture and Mouse Liver. Toxicol. Appl. Pharmacol. 247:60-69.

Salinas, K., Hemmer, M.J, Serrano, J., Higgins, L., Anderson, L.B., Benninghoff, A.D., Williams, D.E and Walker, C. (2010) Isolation of Estrogen-Responsive Vitelline Envelope Protein Fragments from Rainbow Trout (Oncorhynchus mykiss) Plasma Using Mass Spectrometry. Molec. Reprod. Develop. 77:963-970.

Larsen, C.A. and Dashwood, R.H. (2010) (-)-Epigallocatechin-3-gallate Inhibits Met Signaling, Proliferation, and Invasiveness in Human Colon Cancer Cells. Arch. Biochem. Biophys. 501:52-57.

Ho, E. and Dashwood, R.H. (2010) Dietary Manipulation of Histone Structure and Function. World Rev. Nutr. Diet. 101:95-102.

Larsen, C.A., Dashwood, R.H. and Bisson, W.H. (2010) Tea Catechins as Inhibitors of Receptor Tyrosine Kinases: Mechanistic Insights and Human Relevance. Pharmacol. Res. 62:457-464.

Huang, H., Huang, C., Wang, L., Ye, X., Bai, C., Simonich, M.T., Tanguay, R.L. and Dong, Q. (2010) Toxicity, Uptake Kinetics and Behavior Assissment in Zebrafish Embryos Following Exposure to Perfluorooctanesulphonicacid (PFOS). Aquat. Toxicol. 98:139-147.

Hillwalker, W.E., Allan, S.E., Tanguay, R.L. and Anderson, K.A. (2010) Exploiting Lipid-Free Tubing Passive Samplers and Embryonic Zebrafish to Link Site Specific Contaminant Mixtures to Biological Responses. Chemosphere 79:1-7.

Tal, T.L., Franzosa, J.A. and Tanguay, R.L. (2010) Molecular Signaling Networks that Choreograph Epimorphic Fin Regeneration in Zebrafish- a Mini-Review. Gerontology 56:231-240.

ODonnell, E.F., Saili, K.S., Koch, D.C., Kopparapu, P.R., Farrer, D., Bisson, W.H., Mathew, L.K., Sengupta, S., Kerkvliet, N.I., Tanguay, R.L. and Kolluri, S.K. (2010) The Anti-Inflammatory Drug Leflunomide is an Agonist of the Aryl Hydrocarbon Receptor. PLoS One Oct 1; 5(10). pii:e13128.

Truong, L. Harper, S.L. and Tanguay, R.L. (2011) Evaluation of Embryotoxicity Using the Zebrafish Model. Methods Molec. Biol. 691:271-279.

Wang, R., Dashwood, W.M., Nian, H., Löhr, V.C., Fischer, K.A., Tsuchiya, N., Nakagama, H., Ashktorab, H. and Dashwood, R.H. (2010) NADPH Oxidase Overexpression in Human Colon Cancers and Rat Colon Tumors Induced by 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Int. J. Cancer, in press.

Hsu, A., Bruno, R.S., Löhr, CV, Taylor, A.W., Dashwood, R.H., Bray, T.M. and Ho, E. (2010) Dietary Soy and Tea Mitigate Chronic Inflammation and Prostate Cancer Via NKkappaB Pathway in the Noble Rat Model. J. Nutr. Biochem., in press.

Riley, R.T., Voss, K.A., Coulombe, R.A. Jr., Pestka, J.J. and Williams, D.E. (201x) Developing Mechanism-Based and Exposure Biomarkers for Mycotoxins in Animals, in Determining Mycotoxins and Mycotoxigenic Fungi in Food and Feed, S. De Saeger (ed.), Woodhead Publishing Limited, Cambridge, U.K., in press.

Benninghoff, A.D., Bisson, W.H., Koch, D.C., Ehresman, D.J., Kolluri, S.K. and Williams, D.E. (201x) Estrogen-Like Activity of Perfluoralky Acids In Vivo and Interaction with Human and Rainbow Trout Estrogen Receptors In Vitro. Toxicol. Sci. in press.

Rajendran, Praveen, Williams, David E., Ho, Emily and Dashwood, Roderick H. (2011) Metabolism as a Key to Histone Deacetylase Inhibition. Crit. Rev. Biochem. Molec. Biol., in press.

Choi, S.-H.; Lee, S.-H.; Kim, H.-J.; Lee, I.-S.; Kozukue, N.; Levin, C. E.; Friedman, M. Changes in free amino acid, phenolic, chlorophyll, carotenoid, and glycoalkaloid contents in tomatoes during 11 stages of growth and inhibition of cervical and lung human cancer cells by green tomato extracts. J. Agric. Food Chem. 2010, 58, 7547-7556.

Choi, S. P.; Kim, S. P.; Kang, M. Y.; Nam, S. H.; Friedman, M. Protective effects of black rice bran against chemically-induced inflammation of mouse skin. J. Agric. Food Chem. 2010, 58, 10007-10015. Friedman, M. Origin, microbiology, nutrition, and pharmacology of D-amino acids. Chemistry & Biodiversity. 2010, 7, 1491-1530. Invited review.

Friedman, M.; Juneja, V. K. Review of antimicrobial and antioxidative activities of chitosans in food. J. Food Protection 2010, 73, 1737-1761.

Juneja, V. K.; Hwang, C.-A.; Friedman, M. Thermal inactivation and postthermal treatment growth during storage of multiple Salmonella serotypes in ground beef as affected by sodium lactate and oregano oil. J. Food Sci. 2010, 75, M1-M6.

Jung, J.-K.; Lee, S.-U.; Kozukue, N.; Levin, C. E.; Friedman, M. Distribution of phenolic compounds and antioxidative activities in parts of sweet potato (Ipomoea batata L.) plants and in home processed roots. J. Food Composition and Analysis 2010, 23, published online: http://dx.doi.org/10.1016/j.jfca.2010.1003.1025.

Rasooly, R.; Do, P. M.; Friedman, M. Inhibition of biological activity of Staphylococcal enterotoxin A (SEA) by apple juice and apple polyphenols. J. Agric. Food Chem. 2010, 58, 5421-5426. R asooly, R.; Do, P. M.; Levin, C. E.; Friedman, M. Inhibition of Shiga toxin 2 (Stx2) in apple juices and its resistance to pasteurization. J. Food Sci. 2010, 75, M296M301.

Rasooly, R.; Do, P. M.; Griffey, S. M.; Vilches-Moure, J. G.; Friedman, M. Ingestion of Shiga toxin 2 (Stx2) causes histopathological changes in kidney, spleen and thymus tissues and mortality in mice. J. Agric. Food Chem. 2010, 58, 92819286.

Rayburn, J. R.; Friedman, M. L-cysteine, N-acetyl-L-cysteine, and glutathione protect Xenopus laevis embryos against acrylamide-induced malformations and mortality in the Frog Embryo Teratogenesis Assay (FETAX). J. Agric. Food Chem. 2010, 58(20), 11172-11178. Ravishankar, S.; Zhu, L.; Olsen, C. W.; McHugh, T. H.; Friedman, M. Edible apple film wraps containing plant antimicrobials inactivate foodborne pathogens on meat and poultry products. J. Food Sci. 2009, 74, M440-M445.

Ravishankar, S.; Zhu, L.; Reyna-Granados, J.; Law, B.; Joens, L.; Friedman, M. Carvacrol and cinnamaldehyde inactivate antibiotic-resistant Salmonella enterica in buffer and on celery and oysters. J. Food Protection. 2010, 73, 234-240.

Tsuchida, H.; Kozukue, N.; Han, G.-P.; Choi, S.-H.; Levin, C. E.; Friedman, M. Low-temperature storage of cucumbers induces changes in the organic acid content and in citrate synthase activity. Postharvest Biology and Technology 2010, 58, 129-134.

02/22/2022