11/12/2007

Journal Publications:


1. Ridpath JF, CS Mark, CCL Chase, AC Ridpath, and JD Neill. Febrile response and decrease in circulating lymphocytes following acute infection of white tail deer fawns with either a BVDV1 or a BVDV2 strain. J Wildlife Dis. in press.


2. Zimmerman AD, Buterbaugh RE, Herbert JM, Hass JM, Frank NE, Luempert III LG, Chase CCL. Efficacy of bovine herpesvirus-1 inactivated vaccine against abortion and stillbirth in pregnant heifers. JAVMA, 2007; 231:13861389.


3. Corbeil LB, Arnold KF, Kimball R, Berghaus L, Gershwin LJ. Specificity of IgG and IgE antibody responses to Haemophilus somnus infection of calves. Vet Immunol Immunopathol. 2006 Sep 15;113(1-2):191-9.


4. Berghaus LJ, Corbeil LB, Berghaus RD, Kalina WV, Kimball RA, Gershwin LJ. Effects of dual vaccination for bovine respiratory syncytial virus and Haemophilus somnus on immune responses. Vaccine. 2006 Aug 14;24(33-34):6018-27.


5. Donovan DC, Reber AJ, Gabbard JD, Aceves-Avila M, Galland KL, Holbert KA, Ely LO, Hurley DJ. Effect of maternal cells transferred with colostrum on cellular responses to pathogen antigens in neonatal calves. Am J Vet Res, 2007; 668:778-782.


6. Wiggins MC, Woolums AR, Sanchez S, Hurley DJ, Cole DJ, Ensley DT, Pence ME. Prevalence of Mycoplasma bovis in backgrounding and stocker cattle operations. J Am Vet Med Assoc. 2007; 230:1514-1518.


7. Al-Mubarak-A, Simon, J, Coats, C, Okemba, JD, Burton, MD, and Chowdhury, SI. Glycoprotein E(gE) specified by Bovine herpesvirus type5 (BHV-5) enables trans-neuronal virus spread and neurovirulence without being a structural component of enveloped virions. Virology. 2007; 365:398-409.


8. Butchi, NB, Jones, C, Perez, S, Doster, A, and Chowdhury,SI. Role of Envelope protein Us9 in the anterograde transport of BHV-1 following reactivation in the Trigeminal Ganglia . J. Neurovirology. 2007; 13(4):384-388.


9. Muhammad-Tahir, Z, Alocilja, EC, and Grooms, DL. Indium Tin Oxide-Polyaniline Biosensor: Fabrication and Characterization. Sensors. 2007; 7:1123-1140.


10. Lee, S-R, Pharr, GT, Boyd, BL, Pinchuk, LM*. Bovine viral diarrhea viruses modulate toll-likereceptors, cytokines and co-stimulatory molecules genes expression in bovine peripheral blood monocytes.Comparat Immunol Microbiol Infect Dis. 2007; doi:10.1016/j.cimid.2007.06.006S.


11. Thomas, CJ, Hoet, AE, Sreevatsan, S, Wittum, TE, Briggs, RE, Duff, GC, and Saif, LJ. Transmission of bovine coronavirus and serologic responses in feedlot calves under field conditions. Am J Vet Res. 2006; 67:1412-20.


12. Fach, SJ, Brockmeier, SL, Hobbs, LA, Lehmkuhl, HD, and Sacco, RE. Pulmonary dendritic cells isolated from neonatal and adult ovine lung tissue. Vet Immunol Immunopathol. 2006; 112:171-82.


13. Kawashima, K, Meyerholz, DK, Gallup, JM, Grubor, B, Lazic, T, Lehmkuhl, HD, and Ackermann MR. Differential expression of ovine innate immune genes by preterm and neonatal lung epithelia infected with respiratory syncytial virus. Viral Immunol. 2006; 19:316-23.


14. Fach, SJ, Meyerholz, DK, Gallup, JM, Ackermann, MR, Lehmkuhl, HD, and Sacco, RE. Neonatal ovine pulmonary dendritic cells support bovine respiratory syncytial virus replication with enhanced interleukin IL-4 and IL-10 gene transcripts. Viral Immunol. 2007; 20:119-30.


15. Meyerholz, DK, Gallup, JM, Lazic, T, de Macedo, MM, Lehmkuhl, HD, and Ackermann MR. Pretreatment with recombinant human vascular endothelial growth factor reduces virus replication and inflammation in a perinatal lamb model of respiratory syncytial virus infection. Viral Immunol. 2007; 20:188-96.


16. Gatto, NT, Estes, DM, Confer, AW, Whitworth, LC, and Murphy, GL. Lung Lesions in SCID-bo and SCID-bg Mice after Intratracheal inoculation with Wild-type or Leucotoxin-deficient Mutant Strains of Mannheimia haemolytica Serotype 1. J Comp Patho. 2006; 134:355-365.


17. Atapattu, DN and Czuprynski CJ. Mannheimia haemolytica leukotoxin binds to lipid rafts in bovine lymphoblastoid cells (BL-3) and is internalized in a dynamin-2 and clathrin-dependent manner. Infect Immun. 2007 Aug 6; [Epub ahead of print]


18. Behling-Kelly, E, Vonderheid, H, Kim, KS, Corbeil, LB, and Czuprynski, CJ. Roles of cellular activation and sulfated glycans in Haemophilus somnus adherence to bovine brain microvascular endothelial cells. Infect. Immun. 2006; 74:5311-5318.


19. Behling-Kelly, E, McClenahan, D, Kim, KS, and Czuprynski, CJ. Viable Haemophilus somnus induce myosin light chain kinase-dependent decrease in brain endothelial cell monolayer resistance. Infect Immun. 2007; Jun 25; [Epub ahead of print]


20. Kuckleburg, CJ, Elswaifi, SF, Inzana, TJ, and Czuprynski, CJ. Expression of phosphorylcholine by Histophilus somni induces bovine platelet aggregation. Infect Immun. 2007; 75:1045-1049.


21. Kuckleburg, CJ, McClenahan, DJ, and Czuprynski, CJ. Platelet activation by Histophilus somni and its lipooligosacharride induces endothelial cell proinflammatory responses and platelet internalization. Shock. 2007, Jul 19; [Epub ahead of print]


22. Lago, A, McGuirk, SM, Bennett, TB, Cook, NB, and Nordlund, KV. Calf respiratory disease and pen microenvironments in naturally ventilated calf barns in winter. J. Dairy Sci. 2006; 89:4014-4025.


23. Sylte, M, Inzana, T, and Czuprynski, CJ. Role of tumor necrosis factor in endothelial cell apoptosis caused by Haemophilus somnus lipooligosaccharide. Vet. Immunol. Immunopathol. 2006; 110:303-309.



Abstracts and Conference Proceedings:


1. Ridpath JF, CS Mark, CCL Chase and JD Neill. Experimental acute BVDV infection in white tail deer fawn. Proceedings of the 39th annual conference of the American Association of Bovine Practitioners, Saint Paul, MN, September 21-23, 2006, p. 271.


2. Ridpath JF, BE Hessman, JD Neill, RW Fulton, DL Step, A Zimmerman and CCL Chase. Evaluating stability, size requirements, viral load and pooling of ear notch samples in BVDV testing. Proceedings of the 49th annual conference of the American Association of Veterinary Laboratory Diagnosticians, Minneapolis, MN, October 12-18, 2006, p. 213.


3. Tigabu B, A Rosa, G Rosa and CCL Chase. Comparison of immune gene expression in normal and BVDV persistently infected cattle. Abstract 2. 66th annual meeting of the North Central Branch of the American Society of Microbiology, Brookings, SD, October 20-21, 2006, p. 21.


4. Halaweish S, Y Fang, I Halaweish, L Braun and C Chase. Expression of recombinant BVDV-nonstructural proteins to study the humoral immune response against BVDV in cattle. Abstract 1. 66th annual meeting of the North Central Branch of the American Society of Microbiology, Brookings, SD, October 20-21, 2006, p. 21.


5. Tigabu B, A. Rosa, G. Rosa, CCL Chase. Comparison of Immune Gene Expression in Normal and BVDV Persistently Infected Cattle. Abstract, p73. 87th annual meeting of Conference of Research Workers in Animal Disease, Chicago, IL, December 3-5, 2006.


6. Halaweish S, Y Fang, I Halaweish, L Braun, C Chase. Expression of recombinant BVDV-Nonstructural Proteins to Study the Humoral Immune Response against BVDV in Cattle. Abstract, p73. 87th annual meeting of Conference of Research Workers in Animal Disease, Chicago, IL, December 3-5, 2006.


7. Mahmoud MM, LJ Braun, A Hippen, M Thomas, and CC Chase. Effect of source of selenium and vitamin E supplementation on performance and immune response in young dairy calves. Abstract, p84. 87th annual meeting of Conference of Research Workers in Animal Disease, Chicago, IL, December 3-5, 2006.


8. Rosenbusch, R. F. Antimicrobial susceptibility of recent isolates of Mycoplasma bovis. Academy of Veterinary Consultants, Spring 2007 Meeting, Oklahoma City, OK, 2007.


9. S-R Lee1*, G. T. Pharr1, L. M. Pinchuk1. Bovine Viral Diarrhea Viruses Modulate Type I IFN and Pro-Inflammatory Cytokines Production via Toll-Like Receptor-Dependent Mechanisms. S.-R. Lee1*, G. T. Pharr1, L. M. Pinchuk1. Oral presentation at CRWAD, Chicago, IL, Dec.3-5, 2006.


10. Lawrence, ML, SC Burgess, S Bridges, B Nanduri, N Wang, and F McCarthy. Experimental annotation of bovine respiratory disease pathogen genomes by proteogenomic mapping. Plant and Animal Genome XV Conference, San Diego, California, 2007.


11. Confer A. Pathogenesis of pulmonary infections with Pasteurellaceae. Proceedings of the 24th Symposium of the Veterinary Comparative Respiratory Society. Jena, Germany, 2006.


12. Trojan B, Ayalew S, Montelongo M, Confer AW. Intranasal Vaccination of Dairy Calves with Mannheimia haemolytica Chimeric PlpE-LKT (SAC89). ASM abstract for presentation at the annual meeting in Toronto, Canada, May 2007.


13. Ayalew S, Stevens KD, Montelongo M, and Confer AW. Mannheimia haemolytica Chimeric Protein Vaccine Composed of the Major Surface-Exposed Epitope of Outer Membrane Lipoprotein PlpE and the Neutralizing Epitope of Leukotoxin. ASM abstract for presentation at the 107th annual meeting in Toronto, Canada, May 2007.


14. Fulton, RW, Braziel, BC, Kautz, K, Burge, LJ, Weaver, GD, and Hessman, B. Bovine Respiratory Syncytial Virus, Bovine Coronavirus and Bovine Viral Diarrhea Virus Diagnosis by PCR Testing of Nasal Swabs. American Association of Bovine Practitioners Annual Meeting Proceedings. St. Paul, MN, September 21-23, 2006.

15. Ridpath, JF, Hessman, BJ, Neill, J, Fulton, RW, and Step, DL. Parameters of Use of Ear Notch Samples for BVDV Testing: Stability, Size Requirements and Viral Load. American Association of Bovine Practitioners Annual Meeting Proceedings. St. Paul, MN., September 21-23, 2006.


16. Fulton, RW, Whitley, EM, Johnson, BJ, Kapil, S, Ridpath, JF, Burge, LJ, Cook, BJ, and Confer, AW. Bovine Viral Diarrhea Virus Persistent Infectious in Beef Breeding Herds; Utilization of Immunohistochemistry and Antigen Capture ELISA on Ear Notches. 49th Annual Meeting of AAVLD. Minneapolis, MN, October 12-15, 2006.


17. Fulton, RW, Elam, N, Hessman, BE, Johnson, BJ, Kapil, S, Ridpath, JF, Burge, LJ, Braziel, BC, Kautz, K, and Reck, A. Bovine Viral Diarrhea Virus Persistently Infected and Acutely Infected Calves: Assays for Viral Infectivity, Polymerase Chain Reaction Analysis, and Antigen Detection. 49th Annual Meeting of AAVLD. Minneapolis, MN, October 12-15, 2006.


18. Fulton, RW. Detecting Persistently Infected BVDV Cattle in Cow-Calf Herds. Academy of Veterinary Consultants Meeting, Denver, CO, December 1, 2006.


Other (Ph.D Dissertations):


1. Tigabu B., PhD. The Effect of Bovine Viral Diarrhea Virus on Immune Gene Expression of Bovine Leukocytes. South Dakota State University, 2007.


2. Chris Kuckleburg, PhD. Bovine platelets activated by Histophilus somni induce endothelial cell activation and apoptosis. University of Wisconsin-Madison, 2007.


3. Erica Behling-Kelly, PhD. Interactions Between Haemophilus somnus and Bovine Brain Endothelial Cells. University of Wisconsin-Madison, 2007.

10/20/2008

JOURNAL PUBLICATIONS:-


Gershwin LJ, Gunther RA, Hornof WJ, Larson RF. Effect of infection with bovine respiratory syncytial virus on pulmonary clearance of an inhaled antigen in calves. Am J Vet Res 3:416-422, 2008.


Geertsema RS, Worby C, Kruger RP, Tagawa Y, Russo R, Herdman DS, Lo K, Kimball RA, Dixon J, Corbeil LB. Protection of mice against H. somni septicemia by vaccination with recombinant immunoglobulin binding protein subunits. Vaccine 35:4506-4512, 2008.


Reber AJ, Donovan DC, Gabbard J, Galland K, Aceves-Avila M, Holbert KA, Marshall L, Hurley DJ. Transfer of maternal colostral leukocytes promotes development of the neonatal immune system. II. Effects on neonatal lymphocytes. Vet. Immunol Immunopath 123:305-313, 2008.


Reber AJ, Donovan DC, Gabbard J, Galland K, Aceves-Avila M, Holbert KA, Marshall L, Hurley DJ. Transfer of maternal colostral leukocytes promotes development of the neonatal immune system. II. Effects on monocyte lineage cells. Vet Immunol Immunopath 123:186-196, 2008.


Chase CCL, Hurley DJ, Reber AJ. Neonatal immune development in the calf and its impact on vaccine response. Vet Clin North Am Food Anim Pract 24:87-104, 2008.


Funk RA, Thomson DU, Renter DG, White BJ, Guillosou S. Comparison of pooled testing to individual testing with an ear-notch antigen capture ELISA testing for bovine viral diarrhea virus. Bovine Practitioner 42:93-97, 2008.


Funk RA, Thomson DU, White BJ, Renter DG, Rust RR. Effects of ear-notch sample handling on reliability of antigen-capture ELISA attesting for BVDV. Bovine Practitioner 42:45-49, 2008.


Nickell JS, White BJ, Larson RL, Blasi DA, Renter DG. Comparison of short term health and performance effects related to prophylactic administration of either tulathromycin or tilmicosin to beef stocker calves. Vet Therapeut 9:147-156, 2008.


Sanderson MW, Dargatz DA, Wagner BA. Risk factors for initial respiratory disease morbidity counts in US feedlots. Canad Vet J 49:373-378, 2008.


Muhammad-Tahir Z, Alocilja EC, Grooms DL. Indium tin oxide polyaniline biosensor: fabrication and characterization. Sensors 7:1123-11490, 2007.


Jin JH, Zhang D, Alocilja EC, Grooms DL. Label-0free DNA sensor on nano-porous silicon-polypyrrole chip for monitoring Salmonella species. IEEE Sensors J 8:891-8954, 2008.


Nanduri B, Lawrence ML, Peddinti DS, Burgess SC. Effects of sub-minimum inhibitory concentrations of antibiotics on the Pasteurella multocida proteome: a systems approach. Comparative ands Functional Genomics e-pub 254836, 2008.


Pinchuk GV Lee S-R, Nanduri B, Honsiger KL, Stokes JV, Pinchuk LM. BVDV differentially alter the expression of the protein kinases and related proteins affecting the development of infection and anti-viral mechanisms in bovine monocytes. Biochim Biophys Acta 1784: 1234-1247, 2008.


Lee S-R, Pharr GT, Boyd BL, Pinchuk LM. BVDV modulate toll-like receptors, cytokines and co-stimulatory molecule gene expression in bovine PBMC. Comp Immun Microbiol Infect Dis 31:403-418, 2008.


Perez S, Meyer F, Saira K, Doster A, Jones C. Premature expression of the latency related (LR) RNA correlates with higher levels of beta-interferon RNA expression in productively infected cells. J Gen Virol 89:1338-1345, 2008.


Geiser V, Rose S, Jones C. BHV-1 induces cell death by a cell type dependent fashion. Microb Pathogen 44:459-466, 2008.


Liu ZF, Brum MCS, Doster A, Jones C, Chowdhury SI. A BHV-1 mutant virus specifying a carboxyl terminal truncation of glycoprotein E is defective in anterograde neuronal transport in rabbits and calves. J Virol 82:7432-7442, 2008.


Brum MCS, Coats C, Sangena BR, Doster A, Jones C, Chowdhury SI. BHV-1 anterograde neuronal transport from trigeminal ganglia to nose and eye requires glycoprotein E. In Press, J Neurovirol.


Zimmerman AD, Butterbaugh RE, Herbert JM, Haas JM, Frank NE, Luempert LG, Chase CCL. Efficacy of BHV-1 inactivated vaccine against abortion and stillbirth in pregnant heifers. JAVMA 231:1386-1389, 2007.


Ridpath JF, Mark CS, Chase CCL, Ridpath AC, Neill JD. Febrile response and decrease in circulating lymphocytes following acute infection in white tail deer fawns with either BVDV1 or a BVDV2 strain. J Wildlife Dis 43:653-659, 2007.


Atapattu DN, Czuprynski CJ. Mannheimina haemolytica leukotocxin binds to lipid rafts of bovine lymphoblastoid cells (BL-3) and is internalized in a dynamin-2 and clathrin-dependent manner. Infect Immun 75:4719-4725.


Behling-Kelly E, McClenahan D, Kim KS, Czuprynski. Viable Haemophilus somnus induce myosin light chain kinase-dependent decrease in brain endothelial cell monolayer resistance. Infect Immun 75:4572-4581.


Behling-Kelly E, Kim KS, Czuprynski CJ. Haemophilus somnus activation of brain endothelial cells: potential role for local cytokine production and thrombosis in CNS infection. Thromb Haemostas 98:823-830, 2007.


Kuckleburg CJ, McClenahan DJ, Czuprynski CJ. Platelet activation by Histophilus somni and its LOS induces endothelial cell pro-inflammatory cytoikine responses and platelet internalization. Shock 29:189-196, 2008.


Kuckleburg CJ, Tiwari R, Czuprynski CJ. Endothelial cell apoptosis induced by bacteria-activated platelets requires caspase-8 and -9 and generation of reactive oxygen species. Thromb Haemost 99:363-372, 2008.


McClenahan D, Hellebrand K, Atapattu D, Aulik N, Carlton S, Kapuir A, Czuprynski CJ. Effects of LPS and Mannheimina haemolytica leukotoxin on bovine lung microvascular endothelial cells and alveolar epithelial cells. Clin Vaccine Immunol 15:338-347, 2008.








REVIEWS AND BOOK CHAPTERS:-


Jones C, Chowdhury SI. A review of the biology of BHV-1. Its role as a cofactor in the BRD complex, and development of improved vaccines. Adv An Health 8:187-205, 2008.


Behling-Kelly E, Czuprynski CJ. Endothelial cells as active participants in veterinary infections and inflammatory disorders. Anim. Health Res Rev 8:47-58, 2007.


Rosenbusch, R. F. Chapter 43: Mycoplasmas in bovine respiratory disease. In Current Veterinary Therapy Food Animal Practice Vol. 5, D. E. Anderson and D. M. Rings, eds., Saunders, St. Louis, 2009.








ABSTRACTS AND CONFERENCE PROCEEDINGS:-


Haase C, Quesada M, Mukhtar E, Sharp P, Larson LJ, Thomas C, Schultz RD. Comparative study of three major modified live bovine vaccines for BVDV, BHV-1, PI-3, BRSV, and 5 Leptospira serovars. 88th CRWAD meeting, Dec 2-4, 2007, Chicago. IL.


Reber AJ, Donovan DC, Gabbard J, Gallanfd K, Aceves-Avila M, Holbert KA, Marshall L, Hurley DJ. Transfer of maternal colostral leukocytres promotes development of neonatal lymphocytes. 88th CRWAD meeting, Dec 2-4, 2007, Chicago. IL.


Woolums AR. Vaccination of calves  New information on the effects of maternal antibody. 40th AABP convention, Sep 20, 2007, Vancouver, BC.


Rosenbusch RF, Lee N, Christensen L. Identification of Mycoplasma bovis genes involved in uptake of unopsonized mycoplasmas by activated macrophages. 17th International Organization for Microbiology Congress, Tianjin, China, 2008.


Rosenbusch RF, Lee N, Zamzow DR, Riedell CR, Christensen L. Use of a respiratory tract infection model in cattle to screen transposon 4001 mutants of Mycoplasma bovis. 17th International Organization for Microbiology Congress, Tianjin, China, 2008.


Lee N, Zamzow DR, Riedell, CR, Rosenbusch RF. Development of a transposon 4001 mutant library of a pathogenic Mycoplasma bovis strain. 17th International Organization for Microbiology Congress, Tianjin, China, 2008.


Rosenbusch RF, Zamzow DR, Riedell CD, Lee. N Construction of a random mutant
library of Mycoplasma bovis. 108th General Meeting of the American Society for Microbiology, Boston, 2008.


Lee N, Zamzow DR, Rosenbusch RF. Identification of the origin of replication in the chromosome of Mycoplasma bovis and its use to construct a replicative plasmid. 108th General Meeting of the American Society for Microbiology, Boston, 2008.


Berghaus LJ, Vandenplas ML, Galland KL, Davis CE, Hurley KAE, Blas-Machado U, Woolums AR. Comparison of 3 methods of identification of nasa; BRSV shedding by calves. 88th CRWAD meeting, Dec 2-4, 2007, Chicago. IL.


Woolums AR. The problem of insufficient funding for cattle health research. Presented to the AABP Board of Governors Annual Meeting, March 2008.


Woolums AR. Immune development in the neonatal calf. Minnesota Nutrition satellite conference, Sep 16, 2008, Owatonna, MN.







OTHER (M.S. Thesis):-


Rivera, Jose. Effects of BHV-1 infection on bovine neutrophil adhesion to bronchial epithelial cells in vitro. MS thesis, Madison, WI.

11/11/2009

B.J. White, D.G. Renter. Bayesian estimation of the performance of clinical
observations and harvest lung scores for diagnosing bovine respiratory
disease in post-weaned beef calves. J Vet Diagn Invest July 2009 Vol. 21,
Number 4: 446-453.

A. Babcock, B.J. White, D.G. Renter, S.S. Dritz, D.U. Thomson. Feedlot health and performance effects associated with the timing of respiratory disease treatment. J Anim Sci 2009 87:314-227.

G.A. Hanzlicek, B.J. White, D. Anderson, D. Mosier, D.G. Renter. Pathological and physiological changes following induced Mannheimia pneumonia in beef feeder calves. Amer J Vet Res. Accepted.

B.J. White, G. Hanzlicek, M.W. Sanderson, D.E. Sanderson, R.L. Larson. Prevalence of Mollicutes species in beef feeder calves at arrival and first treatment for bovine respiratory disease. Can Vet J. Accepted.

Shen, W. and C. Jones. 2008. Open reading frame 2 encoded by the latency related gene of bovine herpesvirus 1 has anti-apoptosis activity in transiently transfected neuroblastoma cells. J. Virology, 82:10940-10945.

Saira, K., S. Chowdhury, N. Gaudreault, L. da Silva, G. Henderson, A. Doster, & C. Jones. 2008. The zinc RING finger of the bovine herpesvirus 1 encoded bICP0 protein is crucial for viral replication and virulence. J. Virology, 82:12060-12068.

Brum. M.C.S., C. Coats, B.R. Sangena, A. Doster, C. Jones, and S.I. Chowdhury.
2009. Bovine herpesvirus type 1 (BoHV-1) anterograde neuronal transport from trigeminal ganglia to nose and eye requires glycoprotein E. J. Neurovirology, 15:1-6.

Saira, K., Y. Zhou, and C. Jones. 2009. The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) associates with interferon regulatory factor 7 (IRF7), and consequently inhibits beta interferon promoter activity. J. Virology. 83:3977-3981.

Meyer, F. and C. Jones. 2009. C/EBP-alpha cooperates with bTIF to activate the bovine herpesvirus 1 immediate early transcription unit 1 promoter. J. Neurovirology 15:123-130.

Ellis, J., S. Gow, N. Goji, C. Jones, A. Workman, G. Henderson, G. Alaniz, and T. Meinert. Efficacy of a combination viral vaccine in protecting cattle from experimental infection with bovine herpesviruses-1 isolated from recent vaccine breaks. J. of American Veterinary Medical Association, IN PRESS.

Workman, A., S. Perez, A. Doster, and C. Jones. 2009. Dexamethasone treatment of calves latently infected with bovine herpesvirus 1 (BHV-1) leads to activation of the bICP0 early promoter, in part by the cellular transcription factor C/EBP-alpha. J. Virology, IN PRESS.

Taylor JD, Fulton RW, Dabo SM, Lehenbauer TW, Step DL, Confer AW. Molecular characterization of Pasteurella multocida isolates from fatal cases of bovine respiratory disease. Can Vet J, 2009, in press
Taylor JD, Fulton RW, Lehenbauer TW, Step DL, Confer AW. The epidemiology of bovine respiratory disease: What is the evidence for preventive measures? Can Vet J, 2009, in press
Confer AW, Ayalew S, Step D L, Trojan B, Montelongo M. Intranasal vaccination of young Holstein calves with Mannheimia haemolytica chimeric protein PlpE-LKT (SAC89) and cholera toxin Vet Immun & Immunopathol, 2009, available online as of May 23, 2009
Singh K, Confer AW, Hope JC, Rizzi T, Wyckoff JW, Weng HY, Ritchey JW. Cytokine mRNA modulation in bovine alveolar macrophages challenged with the wild type and leukotoxin-deficient mutant of Mannheimia haemolytica. Mol Pathog, accepted with revisions, 2009
Ayalew S, Step DL, Montelongo M, Confer AW. Intranasal vaccination of calves with Mannheimia haemolytica chimeric protein containing the major surface epitope of outer membrane lipoprotein PlpE, the neutralizing epitope of leukotoxin, and cholera toxin subunit B. Vet Immun & Immunopathol, In press, 2009.
Step, D.L., Krehbiel, C.R., DePra, H.A., Cranston, J.J., Fulton,R.W.,Kirkpatrick,J.A., Gill, D.R., Payton, M.E., Montelongo, M.A., Confer, A.W.: Effects of Commingling Beef Calves from Different Sources and Weaning Protocols During a Forty-Two-Day Receiving Period on Performance and Bovine Respiratory Disease. Journal of Animal Science. 86:1-13, 2008.
Step, D.L., Litherland, N.B., Burciaga-Robles, L.O., Breshears, M.A., Krehbiel, C.R., Confer, A.W., Fulton, R.W., Morgan, G.L., Thornsberry, R.M., Fassig, S.M.: Clinical Observations, Biochemical Data, and Postmortem and Histopathologic Findings in Young Dairy Calves Fed Zeolite Clinoptilolite Binder Combined with Milk Replacer. American Journal for Veterinary Research 69: 1587-1594, 2008.

Hessman, B.E., Fulton, R.W., Sjeklocha, D.B., Murphy, T.A., Ridpath, J.F., Payton, M.E.: Evaluation of the Economic Effects and the Health and Performance of the General Cattle Population After Exposure to Cattle Persistently Infected with Bovine Viral Diarrhea Virus in a Starter Feedlot. American Journal for Veterinary Research. 70:73-85, 2009.

Fulton, R.W., Hessman, B.E., Ridpath, J.F., Johnson, B.J., Burge, L.J., Kapil.S. Braziel, B., Kautz, K., Reck, A.: Multiple Diagnostic Tests to Identify Cattle with Bovine Viral Diarrhea Virus and Duration of Positive Tests in Persistently Infected Cattle. In Press. Canadian Journal for Veterinary Research. 73: 117-124, 2009.

Fulton, R.W., Whitley, E.M., Johnson, B.J., Ridpath, J.F., Kapil, S., Burge, L.J., Cook, B.J., Confer, A.W.: Beef Herds in a South Central United States Study: Prevalence of Bovine Viral Diarrhea Virus (BVDV) Persistently Infected Cattle and BVDV Subtypes in Affected Cattle. In press. October 2009. Canadian Journal for Veterinary Research

Step, D.L., Krehbiel, C.R.., Burciaga-Robles, LO., Holland, B.P., Fulton,R.W., Confer,A.W., Hutcheson, J., Brister, D., Newcomb,H., Bechtol, D.: A Comparison of Single Vaccination and Revaccination with a Modified Live BHV1-BVDV( type 1 and 2-PI3V-BRSV Vaccine in the Prevention of Bovine Respiratory Disease. Accepted for publication .2009. Journal of American Veterinary Medical Association

Ridpath, J.F., Fulton, R.W.: Knowledge Gaps Impacting the Development of BVDV Control Programs in the United States. 2009. Accepted for publication. 2009. Journal of American Veterinary Medical Association.

Fulton, R.W., Blood, K.S., Panciera, R.J., Payton, M.E., Ridpath, J.F., Confer, A.W., Saliki, J.T., Burge, L.J., Welsh, R.D., Johnson, B.J., Reck. A.: Lung Pathology and Infectious Agents in Fatal Feedlot Pneumonias and Relationship with Mortality, Disease Onset, and Treatments. Journal of Veterinary Diagnostic Investigation 21: July 2009, in press.

Chase CCL, LJ. Braun, P Leslie-Steen, T Graham, D Miskimins JF Ridpath. 2008. Bovine Viral Diarrhea Virus Multi-Organ Infection in Two White-tailed Deer in Southeastern South Dakota. J Wildlife Dis 44:753-759

Ridpath JR, EA Driskell, CCL Chase, JD Neill, MV Palmer, BW Broderson. Reproductive tract disease associated with inoculation of pregnant white-tailed deer with bovine viral diarrhea virus. AJVR 69:1630-1636.

Zimmerman AD, RE Buterbaugh, JA Schnackel, CCL Chase. Efficacy of a modified-live virus vaccine administered to calves with maternal antibodies and challenged seven months later with a virulent bovine viral diarrhea type 2 virus. The Bovine Practitioner 43:35-43.

Kuckleburg, C. J., D. J. McClenahan, and C. J. Czuprynski. 2008. Platelet activation by Histophilus somni and its LOS induces endothelial cell pro-inflammatory responses and platelet internalization. Shock 29:189-196.

Kuckleburg CJ, Tiwari R, Czuprynski CJ. 2008. Endothelial cell apoptosis induced by bacteria-activated platelets requires caspase-8 and -9 and generation of reactive oxygen species. Thromb. Haemost. 99:363-372.

McClenahan, D., K. Hellenbrand, D. Atapattu, N. Aulik, D. Carlton, A. Kapur, and C.J. Czuprynski. 2008. Effects of lipopolysaccharide and Mannheimia haemolytica leukotoxin on bovine lung microvascular endothelial cells and alveolar epithelial cells. Clin. Vaccine Immunol. 15:338-347.

Atapattu DN, Albrecht RM, McClenahan DJ, Czuprynski CJ. 2008. Dynamin-2-dependent targeting of Mannheimia haemolytica leukotoxin to mitochondrial cyclophilin D in bovine lymphoblastoid cells. Infect Immun. 76:5357-5365.

Kisiela DI, Czuprynski CJ.2009. Identification of Mannheimia haemolytica adhesins involved in binding to bovine bronchial epithelial cells. Infect Immun. 2009 77:446-455.

McClenahan D, Hillenbrand K, Kapur A, Carlton D, Czuprynski C. 2009. Effects of extracellular ATP on bovine lung endothelial and epithelial cell monolayer morphologies, apoptoses, and permeabilities. Clin Vaccine Immunol. 16:43-48.

Atapattu DN, Aulik NA, McCaslin DR, Czuprynski CJ. 2009. Brief heat treatment increases cytotoxicity of Mannheimia haemolytica leukotoxin in an LFA-1 independent manner. Microb Pathog. 46:159-165.

Rivera-Rivas JJ, Kisiela D, Czuprynski CJ. 2009. Bovine herpesvirus type 1 infection of bovine bronchial epithelial cells increases neutrophil adhesion and activation. Vet Immunol Immunopathol. Apr 11. [Epub ahead of print].

Tiwari R, Sullivan J, Czuprynski CJ. 2009. PECAM-1 is involved in neutrophil transmigration across Histophilus somni treated bovine brain endothelial cells. Microb Pathog. Jun 12. [Epub ahead of print]

Presentations

Woolums AR and Chase CCL. New discoveries in cattle health: how your actions influence funding decisions. Proceedings of the 41st Meeting of the American Association of Bovine Practitioners. September 25-27, 2008. Charlotte, NC, p. 205-208.

Krunkosky TM, Jarrett CL, Ard MB, Bettis CL, Berghaus LJ, Hurley KAE, Woolums AR. Establishment of Bovine Primary Respiratory Epithelial Cell Cultures From Live Calves and Evaluation of Cell Responses to Bovine Respiratory Syncytial Virus Infection. Proceedings of the 89th Annual Meeting of the Conference for Research Workers in Animal Disease. December 7-9, 2008. Chicago, IL, p. 155.

Woolums AR. Practical approaches to vaccination of the calfvaccinating in the face of maternal antibody. 15th American Dairy Science Association Discover Conference on Food Animal Agriculture: Biology of the Calf, Birth to 4 Months. Nov. 16-19, 2008. Roanoke, VA.

Woolums AR. The bovine immune response to BRSV infection: helpful or harmful? Western Canadian Association of Bovine Practitioners 18th Annual Conference. January 15-17, 2009. Saskatoon SK, Canada.

Woolums AR. Effectively vaccinating calves to prevent respiratory disease. Western Canadian Association of Bovine Practitioners 18th Annual Conference. January 15-17, 2009. Saskatoon SK, Canada.

Woolums AR. Feedlot AIP: what the heck causes it? Western Canadian Association of Bovine Practitioners 18th Annual Conference. January 15-17, 2009. Saskatoon SK, Canada.

Woolums AR, Krunkosky TM, Jarrett CL, Ard MB, Berghaus LJ, Bettis CL, Hurley KAE. Development of primary bovine bronchial epithelial cell (BBEC) cultures from live calves, and evaluation of cell responses to viral infection. 2009 American College of Veterinary Internal Medicine Annual Forum, June 3-6, 2009, Montreal QC, Canada.

Berghaus LJ, Blas-Machado U, Vandenplas ML, Galland KL, Davis CE, Hurley KAE, Woolums AR. Comparison of three methods of identification of nasal BRSV shedding in calves. 5th International Veterinary Vaccines and Diagnostics Conference, July 19-23, Madison, WI, P12.

Woolums A, Krunkosky T, Jarrett C, Ard M, Bettis C, Berghaus L, Hurley K, Kyser J. Establishment of bovine primary bronchial epithelial cell cultures from live calves and evaluation of cell responses to bovine respiratory syncytial virus (BRSV) infection. 2009 Bovine Respiratory Disease Symposium, August 5-6, 2009, Colorado Springs, CO, p. 82.

Hurley DJ. Role of maternally derived white blood cells passed in the colostrum on immune function. 15th American Dairy Science Association Discover Conference on Food Animal Agriculture: Biology of the Calf, Birth to 4 Months. Nov. 16-19, 2008. Roanoke, VA.

Hurley DJ. The transfer of maternal immunity and its impact on calf health and productivity. Academy of Veterinary Consultants Summer Meeting, August 6-8, 2009.

Hurley DJ. An overview of the host immune response to bacterial and viral pathogens. Academy of Veterinary Consultants Summer Meeting, August 6-8, 2009.

Rosenbusch, R. F., and N. Lee. Polyamine transport as virulence factor in Mycoplasma bovis: role in resistance to attack by macrophages. Poster G-007, 109th General Meeting of the American Society for Microbiology, Philadelphia, PA, 2009.

Rosenbusch, R.F., N. Lee, and L. Christensen. Identification of Mycoplasma
bovis genes involved in uptake of unopsonized mycoplasmas by activated
macrophages. 17th International Organization for Microbiology Congress, Poster
133, Tianjin, China, 2008.

Rosenbusch, R.F., N. Lee, D. R. Zamzow, C. D. Riedell, and L. Christensen. Use of a respiratory tract infection model in cattle to screen transposon 4001 mutants of Mycoplasma bovis. 17th International Organization for Microbiology Congress, Presentation in Seminar IV: Molecular and cell biology of mollicutes, Tianjin, China, 2008.

Lee, N., D. R. Zamzow, C. D. Riedell, and R. F. Rosenbusch. Development of a transposon 4001 mutant library of a pathogenic Mycoplasma bovis strain. 17th International Organization for Microbiology Congress, Poster 207, Tianjin, China, 2008.

Fulton, R.W., Blood, K.S., Panciera, R.J., Payton, M. Ridpath, J.F., Saliki, J.T., Burge, L.J., Confer, A.W., Welsh, R.D., Johnson, B.J., Reck.: Lung Pathology and Infectious Agents in Fatal Feedlot Pneumonias and Relationship with Animal and Treatment Information. American Association of Bovine Practitioners Proceedings. September 25-27, 2008. Charlotte, NC.

Taylor, J.D., Fulton, R.W., Lehenbauer, T.W., Dabo, S.M., Confer, A.W.: Molecular Characterization of Pasteurella multocida Isolates from Fatal Feedlot Cases of Bovine Respiratory Disease. American Association of Bovine Practitioners Proceedings. September 25-27, 2008. Charlotte, NC.

Ridpath, J.F., Vander Lay, B.L., Sweiger, S.H., Fulton, R.W., Kirkland, P.D.: Prevalence and Antigenic Differences of Bovine Viral Diarrhea Virus Subgenotypes Isolated from Cattle in Australia and the U.S. 51th Annual Meeting of AAVLD, October 22-27, 2008. Greensboro, NC.

Fulton, R.W., Eberle, R., Burge, L.J., Reck, A.: Development and Use of Indirect ELISA Tests Detecting Antibodies to Bovine Coronavirus and Bovine Viral Diarrhea Virus in Acute and Convalescent Serums of Cattle. 51th Annual Meeting of AAVLD, October 22-27, 2008. Greensboro, NC.

Shelton, T., Hoffman., Fulton.R.W., Ridpath, J.F.: Prevalence of Persistently Infected BVDV Dairy Calves from Dairies with BVDV Vaccination Programs and Distribution of BVDV Subtypes. 4th US BVDV Symposium, January 25-27, 2009. Phoenix, AZ.

Fulton, R.W., Ridpath, J.F., Hessman, B.E., Blood, K.S.: Bovine Viral Diarrhea Virus Variability and Prevalence of BVDV Subtypes in Persistently Infected Cattle Entering Feedlots: BVDV1b as Predominant Subtype. 4th US BVDV Symposium, January 25-27, 2009. Phoenix, AZ.

Ridpath, J.F., Neil, J., Fulton, R.W., Kirkland, P.D.: Bovine Viral Diarrhea Virus Type Subgenotypes Isolated from Cattle in the U.S. and Australia: Prevalence and Antigenic Differences. 4th US BVDV Symposium, January 25-27, 2009. Phoenix, AZ.

Fulton, R.W.: BVD Subtypes: What Matters in the Real World. Western Veterinary Conference. February 17, 2009. Las Vegas, NV.

Confer AW, Ayalew S, Montelongo M, Step DL, Wray JH, Hansen RD, Panciera RJ. Immunity of cattle following vaccination of calves with a Mannheimia haemolytica Chimeric PlpE-LKT (SAC89) protein. International Society of Pasteurellaceae Conference, Sorrento, Italy, October 2008. P403
Ayalew S, Confer AW. Immunoproteomic approach to identify and characterize immunologically important Mannheimia haemolytica outer membrane proteins. International Society of Pasteurellaceae Conference, Sorrento, Italy, October 2008. P402
Confer AW. Comparative Pathology of and Pathogenic Mechanisms in Bovine Bacterial Pneumonia. Proceedings, ACVIM, Montreal, June 2009
Confer AW. Immunity against Mannheimia haemolytica: Current knowledge and New Approaches. Proceedings, ACVIM, Montreal, June 2009
Chase CCL, LJ Braun, L Holler, M Spire. Comparing cytopathic and noncytopathic bovine viral diarrhea virus (BVDV) vaccines: antigen trafficking increased to mucosal surfaces with NCP vaccines. 41st annual conference of the American Association of Bovine Practitioners, Charlotte, NC, September 25-27, 2008.

Chase CCL, LJ Braun, J Ridpath, R Harland. Comparison of the immune response between a pair of noncytopathic and cytopathic bovine viral diarrhea virus (BVDV) type 1 isolates. 41st annual conference of the American Association of Bovine Practitioners, Charlotte, NC, September 25-27, 2008.

Chase CCL, A Young, A Zimmerman, K Gilkerson, K Barling, D Scholz. The induction of a T helper 1 immune response with an inactivated viral vaccine. . 41st annual conference of the American Association of Bovine Practitioners, Charlotte, NC, September 25-27, 2008.

Chase C. Bovine viral diarrhea virus persistent infection of white-tailed deer and their risk to domestic cattle. CSREES Awardee Workshop, Chicago, IL, December 7, 2008.
Zimmerman AD, RE Buterbaugh, JA Schnakel, CCL Chase. 4th US BVDV Symposium, January 26, 2009, Phoenix AZ.

Chase CCL, LJ Braun, L Holler, M Spire. Comparing CP and NCP BVDV vaccines: antigen trafficking increased to mucosal surfaces with NCP vaccines. 4th US BVDV Symposium, January 26, 2009, Phoenix AZ.

Chase CCL, A Young, A Zimmerman, K Gilkerson, K Barling, D Scholz. The induction of a T helper 1 immune response with an inactivated viral vaccine. 4th US BVDV Symposium, January 26, 2009, Phoenix AZ.

Chase CCL, LJ Braun, J Ridpath, R Harland. Comparison of the immune response between a pair of NCP and CP bovine viral diarrhea (BVDV) type 1 isolates. 4th US BVDV Symposium, January 26, 2009, Phoenix AZ.

08/30/2010

Ammari, M. G., McCarthy, F. M., Nanduri, B., Pinchuk, L.M. Analysis of Bovine Viral Diarrhea Viruses-infected monocytes: identification of cytopathic and non-cytopathic biotype differences. BMC Bioinformatics. 11 SUPPL, 2010, MCBIOS, in press.

Atapattu DN, Aulik NA, McCaslin DR, Czuprynski CJ. 2009. Brief heat treatment increases cytotoxicity of Mannheimia haemolytica leukotoxin in an LFA-1 independent manner. Microb Pathog. 46:159-165.


Ayalew S, Step DL, Montelongo M, Confer AW. Intranasal vaccination of calves with Mannheimia haemolytica chimeric protein containing the major surface epitope of outer membrane lipoprotein PlpE, the neutralizing epitope of leukotoxin, and cholera toxin subunit B. Vet Immun & Immunopathol 132: 295-302, 2009

Ayalew S, Confer AW, Hartson SD, Shrestha B. Immunoproteomic Analysis of Outer
Membrane Proteins of Mannheimia haemolytica and Identification of Potential Vaccine Candidates. Proteomics 10: 2151-2164, 2010

Brum M, Coats C., Sangena B.R, Doster.A., Jones, C. and Chowdhury.S.I. (2009). Role of Envelope proteins gE in the anterograde transport of BHV-1 following reactivation in the Trigeminal Ganglia. J. Neuro virology. 15 (2): 196-201.

Brum. M.C.S., C. Coats, B.R. Sangena, A. Doster, C. Jones, and S.I. Chowdhury.
2009. Bovine herpesvirus type 1 (BoHV-1) anterograde neuronal transport from
trigeminal ganglia to nose and eye requires glycoprotein E. J. Neurovirology, 15:1-6.

Burciaga-Robles, L.O., Step, D.L., Krehbiel, C.R., Holland, B.P., Richards, C.J., Montelongo, M.A., Confer, A.W., Fulton, R.W.: Exposure by Persistently Infected Calves with Bovine Viral Diarrhea Virus Type 1b and Subsequent Infection with Mannheimia haemolytica Demonstrating Effects on Clinical Signs and Immune Parameters: Model for Bovine Respiratory Disease Via Viral and Bacterial Interaction. Journal of Animal Science.88: 2166-2178, 2010.

Burciaga-Robles, L.O., Krehbiel, C.R., Step, D.L., Holland, B. P., Richards, C.J., Montelongo, M.A., Confer, A.W., Fulton, R.W.: Effects of Exposure to Calves Persistently Infected with Bovine Viral Diarrhea Virus Type 1b and Mannheimia haemolytica Challenge on Animal Performance, N Balance, and Visceral Organ Mass in Beef Steers. Journal of Animal Science. 88:2179-2188, 2010.

Burge, L.J., Welsh, R.D., Johnson, B.J., Reck. A.: Lung Pathology and Infectious Agents in Fatal Feedlot Pneumonias and Relationship with Mortality, Disease Onset, and Treatments. Journal of Veterinary Diagnostic Investigation 21: 464-477, 2009.

Chowdhury, S. and C. Jones. Bovine herpesvirus type 1 (BHV-1) is an important
cofactor in the bovine respiratory disease complex. Veterinary Clinics of North America: IN PRESS, Food Animal Practice.

Confer AW. Update on bacterial pathogenesis in BRD. Animal Health Res Rev 10: 145-149: 2009.

Confer AW, Ayalew S, Step D L, Trojan B, Montelongo M. Intranasal vaccination of young Holstein calves with Mannheimia haemolytica chimeric protein PlpE-LKT (SAC89) and cholera toxin Vet Immun & Immunopathol 132: 232-236, 2009

Czuprynski, C.J. 2009. Host response to bovine respiratory pathogens. Anim Health Res Rev. 2009 10:141-143.

Ellis, J., S. Gow, N. Goji, C. Jones, A. Workman, G. Henderson, G. Alaniz, and T. Meinert. 2009. Efficacy of a combination viral vaccine in protecting cattle from experimental infection with bovine herpesviruses-1 isolated from recent vaccine breaks. J of American Veterinary Medical Association, 235:563-572.

Fulton, R.W., Whitley, E.M., Johnson, B.J., Ridpath, J.F., Kapil, S., Burge, L.J., Cook, B.J., Conf er, A.W.: Prevalence of Bovine Viral Diarrhea Virus (BVDV) in Persistently Infected Cattle and BVDV Subtypes in Affected Cattle in Beef Herds in South Central United States. Canadian Journal for Veterinary Research 73: 283-291, 2009.

Fulton, R.W.: Bovine Respiratory Disease Research: 1983-2009. Animal Health Research Reviews. 10: 131- 140, 2009.

Hanzlicek G, White B, Anderson D, Mosier D, Renter D. Pathological and
physiological changes following induced Mannheimia pneumonia in beef feeder calves. Amer J Vet Res. Mar 2010. 71(3):359-369.

Hanzlicek G, White B, Renter D, Blasi D. A field study evaluating health,
performance, and behavior differences in crossbred beef calves administered different vaccine-parasiticide product combinations. Vaccine. In press.

Henningson, J.L., C.L.Topliff, L.H.Gil, R.O.Donis, D.J.Steffen, K.M.Eskridge, C.L.Kelling. 2009. Influence of Npro on BVDV virulence and interferon type induction in calves. American Journal of Veterinary Research 70: 1117-1123.

Jaber, T., A. Workman, and C. Jones. Small non-coding RNAs encoded within
the bovine herpesvirus 1 latency related gene can reduce steady state levels of
infected cell protein 0 (bICP0). 2010. J Virology, 84: 62976307

Jones, C. 2009. Regulation of Innate Immune Responses by Bovine Herpesvirus 1
and Infected Cell Protein 0 (bICP0). Viruses 1:255-275.

Jones C, Chowdhury S (2010). Bovine herpesvirus type 1 (BHV-1) is an important cofactor in the bovine respiratory disease complex. Vet. Clin. Food Anim. Practice. (In Press).

Kisiela DI, Czuprynski CJ.2009. Identification of Mannheimia haemolytica adhesins involved in binding to bovine bronchial epithelial cells. Infect Immun. 2009 77:446-455.

Kisiela DI, Aulik NA, Atapattu DN, Czuprynski ,CJ. 2010. N-terminal region of
Mannheimia haemolytica leukotoxin serves as a mitochondrial targeting signal in
mammalian cells. Cell. Microbiol. 12:976-987.

Lee, S.-R., Nanduri, B., Pharr, G. T., Stokes, J. V., Pinchuk, L. M. 2009. Bovine Viral Diarrhea Virus infection affects the expression of proteins related to professional antigen presentation in bovine monocytes. Biochim. Biophys. Acta. 1794:14-22.

Leyh, R.D., Fulton, R.W., Stegner, J.E., Goodyear, M., Witte, S., Taylor, L.P., Johnson, B.J., Step, D.L., Ridpath, J.F., Holland, B.P.: Fetal Protection in Heifers Vaccinated with Modified Live Virus Vaccine Containing Bovine Viral Diarrhea Virus Subtypes BVDV1a and BVDV2a after Challenge with BVDV1b Persistently Infected Cattle. Accepted for publication, 2010. American Journal for Veterinary Research.

Liang, D., L. Chen, I.H. Ansari, L. H. Gil, C.L. Topliff, C.L. Kelling, R.O.Donis. 2009. A replicon trans-packing system reveals the requirement of nonstructural proteins for the assembly of bovine viral diarrhea virus (BVDV) virion. Virology 387:331-340.

McClenahan D, Hillenbrand K, Kapur A, Carlton D, Czuprynski C. 2009. Effects of
extracellular ATP on bovine lung endothelial and epithelial cell monolayer morphologies, apoptoses, and permeabilities. Clin Vaccine Immunol. 16:43-48.

Meyer, F. and C. Jones. 2009. C/EBP-alpha cooperates with bTIF to activate the
bovine herpesvirus 1 immediate early transcription unit 1 promoter. J. Neurovirology 15:123-130.

Panciera RJ, Confer AW. Pathogenesis and pathology of bovine pneumonia. Vet Clin North Amer Food Anim Prac 26: 191-214, 2010

Ridpath, J.F., Fulton, R.W.: Knowledge Gaps Impacting the Development of Bovine Viral Diarrhea Virus Control Programs in the United States. Journal of American Veterinary Medical Association 235: 1171-1179, 2009.

Ridpath, J.F., Fulton, R.W., Kirkland, P.D., Neil, J.: Prevalence and Antigenic Differences Observed Between Bovine Viral Diarrhea Virus Subgenotypes Isolated From Cattle in Australia and Feedlots in the Southwestern United States. Journal of Veterinary Diagnostic Investigation 22; 184-191, 2010.

Rivera-Rivas JJ, Kisiela D, Czuprynski CJ. 2009. Bovine herpesvirus type 1 infection of bovine bronchial epithelial cells increases neutrophil adhesion and activation. Vet Immunol Immunopathol. 131:167-176.

Rose-Dye, T.K., Burciaga-Robles, L.O., Krehbiel, C.R., Step, D.L., Fulton, R.W., Confer. A.W., Richards, C.J.: Rumen Temperature Change Monitored with Remote Reporting Rumen Temperature Boluses Following Challenge with Bovine Viral Diarrhea Virus and Mannheimia haemolytica. Journal of Animal Science, Accepted for publication, 2010.

Rosenbusch R, Woolums A, Grooms D, Larson R. Summary of breakout sessions of 2009 Bovine Respiratory Disease Symposium. An Health Res Rev 2009;10:169-171.

Saira, K., Y. Zhou, and C. Jones. 2009. The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) associates with interferon regulatory factor 7 (IRF7), and consequently inhibits beta interferon promoter activity. J. Virology. 83:3977-3981.

Shanthalingham, S., C.L.Topliff, C.L.Kelling, S.Srikumaran. 2010. Bighorn sheep fetal lung cell line for detection of respiratory viruses. Canadian Journal of Veterinary Research 74:75-77.

Singh K, Ritchey JW, Confer AW. Mannheimia haemolytica: Bacterial-host interactions in bovine pneumonia. Vet Pathol 2010, in press

Singh K, Confer AW, Hope JC, Rizzi T, Wyckoff JW, Weng HY, Ritchey JW. Cytotoxicity and cytokine production by bovine alveolar macrophages challenged with wild type and leukotoxindeficient Mannheimia haemolytica. The Vet J 2010, Epub ahead of print.

Step, D.L., Krehbiel, C.R.., Burciaga-Robles, L.O., Holland, B.P., Fulton, R.W., Confer, A.W., Bechtol, D.T., Brister, D.L., Hutcheson, J.P., Newcomb, H.L.: Comparison of Single Vaccination Versus Revaccination with a Modified Live Virus Vaccine Containing Bovine Herpesvirus-1, Bovine Viral Diarrhea Virus (Types 1a and 2a), Parainfluenza Type 3 Virus, and Bovine Respiratory Syncytial Virus in the Prevention of Bovine Respiratory Disease. Journal of American Veterinary Medical Association 235: 580-587, 2009.

Stevens ET, AD Zimmerman , RE Buterbaugh, K Barling, D Scholz, J Rhoades ,
CCL Chase. 2009. The Induction of a Cell-Mediated Immune Response to
Bovine Viral Diarrhea Virus with an Adjuvanted Inactivated Vaccine. Vet
Therapeutics 10(4):E1-8.

Taylor, J.D., Fulton, R.W., Dabo, S.M., Lehenbauer, T.W., Confer, A.W.: Comparison of Genotypic and Phenotypic Characterization Methods for Pasteurella multocida Isolates from Fatal Cases of Bovine Respiratory Disease. Journal of Veterinary Diagnostic Investigation 22; 366-375, 2010.

Taylor, J.D., Fulton, R.W., Lehenbauer, T.W., Step, D.L., Confer, A.W.: The Epidemiology of Bovine Respiratory Disease: What is The Evidence for Predisposing Factors? In press, 2010. Canadian Veterinary Journal.

Taylor, J.D., Fulton R.W., Lehenbauer T.W., Step D.L, Confer A.W.: The Epidemiology of Bovine Respiratory Disease: What is the Evidence for Preventive Measures? In press, 2010. Canadian Veterinary Journal.

Tiwari R, Sullivan J, Czuprynski CJ. 2009. PECAM-1 is involved in neutrophil transmigration across Histophilus somni treated bovine brain endothelial cells. Microb Pathog. 47:164-170.

Topliff C.L., D.R. Smith, S.L.Clowser,D.J. Steffen, J.N. Henningson, B.W. Brodersen, D. Bedenice, R. J. Callan, C.Reggiardo, K.L. Kurth, C.L. Kelling. 2009. Prevalence of bovine viral diarrhea virus infections in alpacas in the United States. Journal of American Veterinary Medical Association 234:519-529.


White B, Hanzlicek G, Sanderson M, Anderson D, Larson R. Mollicutes
species and Mycoplasma bovis prevalence and association with health outcomes in beef feeder calves at arrival and initial treatment for bovine respiratory disease. Can Vet J. 2010;51: In Press.

Wiggins MC, Woolums AR, Hurley DJ, Sanchez S, Ensley DT, Donovan D. The effect of various Mycoplasma bovis isolates on bovine leukocyte responses. Comp Immunol Microbiol Infect Dis Epub ahead of print. 2010. doi:10.1016/j.cimid.2010.02.001

Woolums A, Chase C, Fulton R, Rosenbusch R, Tremblay R. Introduction to the Proceedings of the 2009 Bovine Respiratory Disease Symposium. An Health Res Rev 2009;10:99.

Workman, A., S. Perez, A. Doster, and C. Jones. 2009. Dexamethasone treatment
of calves latently infected with bovine herpesvirus 1 (BHV-1) leads to activation of the bICP0 early promoter, in part by the cellular transcription factor C/EBP-alpha. J. Virology, 83:8800-8809.

Workman, A. and C. Jones. Bovine herpesvirus 1 (BoHV1) productive infection and bICP0 early promoter activity are stimulated by E2F1. 2010. J Virology, 84: 63086317

12/07/2011

Ammari, M. G., McCarthy, F. M., Nanduri, B., Pinchuk, L.M. 2010. Analysis of Bovine Viral Diarrhea Viruses-infected monocytes: identification of cytopathic and non-cytopathic biotype differences. BMC Bioinformatics. 11 (Suppl 6):S9:1-13.

Ammari, M., McCarthy, F., Nanduri, B., Pinchuk, G., Pinchuk, L. 2010. Analysis of Bovine Viral Diarrhea Viruses-infected monocytes: identification of cytopathic and non-cytopathic differences. December 2010, CRWAD, Chicago

D. Amrine, B.J. White, D.E. Anderson, R.L. Larson, D. Mosier, D. Renter. Behavior and clinical changes in calves with induced Mycoplasma bovis pneumonia. American Association of Bovine Practitioners Annual Conference, St. Louis, MO. September 2011.

Afyalew S, Shrestha B, Montelongo M, Confer AW. Identification and immunogenicity of Mannheimia haemolytica S1 outer membrane lipoprotein PlpF. USDA NIFA Project Directors Meeting, Washington DC, April 2011.

Aulik, N.A., K. M. Hellenbrand, H. Klos, and C. J. CZUPRYNSKI. 2010. Mannheimia haemolytica and its leukotoxin causes neutrophil extracellular trap (NET) formation by bovine neutrophils. Infect. Immun. 78:4454-446.

Aulik, N., K. Hellenbrand, D. Kisiela, and C. CZUPRYNSKI. 2011. Mannheimia haemolytica leukotoxin binds cyclophilin D on bovine neutrophil mitochondria that is not inhibited by cyclosporine A. Microb. Pathogen. 50:168-178.


Ayalew S, Shrestha B, Montelongo M, Confer AW. Identification and Immunogenicity of Mannheimia haemolytica S1 Outer Membrane Lipoprotein PlpF. Proceedings, International Pasteurellaceae Conference, Helsinger, Denmark, 2011; No. 41387.

Ayalew S, Shrestha B, Payton ME, Confer AW. A Rapid Microtiter Plate Method for Determining Serum Complement-Mediated Killing of Mannheimia haemolytica . Proceedings, International Pasteurellaceae Conference, Helsinger, Denmark, 2011; No. 41388.

K. J. Austin, J. L. Seabrook, T. E. Engle, R. K. Peel, C. M. McAllister, B. W. Brigham, R. M. Enns, R. L. Weaber, H. Van Campen, G. H. Loneragan, J. L. Salak-Johnson, and C.C. L. Chase. The effect of morbidity on feedlot performance and carcass quality in feedlot steers. 2010. J. Anim. Sci. Vol. 88 E-Suppl. 2. P. 10.

A.H. Babcock, D. G. Renter, B. J. White, S. Dubnicka, H.M. Scott. Temporal distributions of respiratory disease events within cohorts of feedlot cattle and associations with cattle health and performance indices. Prev Vet Med. 2010, 97:198-219.

L. Berghaus, D. Hurley, R. Berghaus, M. Pence, R. Ellis, J. Saliki, K. Hurley, K. Galland, B.Burdett, S. Nordstrom, A. Woolums. Impact of route and timing of multivalent respiratory vaccination in the face of maternal antibody (IFOMA) on immune responses to booster vaccination at weaning in beef calves. Proceedings of the Conference for Research Workers in Animal Disease (CRWAD), Chicago IL, December 2010

B. W. Brigham, C. M. McAllister, R. K. Peel, H. Van Campen, R. L. Weaber, G. H. Loneragan, J. L. Salak- Johnson, C. C. L. Chase, E. J. Pollak, and R. M. Enns. The relationship of bovine respiratory disease and carcass ultrasound measures. 2010. J. Anim. Sci. Vol. 88 E-Suppl. 2. P. 41

N. Cernicchiaro, D.G. Renter, B.J. White, A.H. Babcock, J.T. Fox. Association between weather conditions and bovine respiratory disease in feedlot calves. American Association of Bovine Practitioners Annual Conference, St. Louis, MO. September 2011.

N. Cernicchiaro, B.J. White, D.G. Renter, A.H. Babcock, L. Kelly, R. Slattery. Effects of transport distance and weight loss during transit on feedlot health and performance. American Association of Bovine Practitioners Annual Conference, St. Louis, MO. September 2011.

Corbett EM, Grooms DL, Bolin SR. Serological Evaluation of Sentinel Calves In a BVDV Eradication Program. J Vet Diagn Invest. 2011;23(3):511-515

Corbett EM, Grooms DL, Bolin SR. Evaluation of Skin Samples by RT-PCR Following Immunization with a Modified-Live Bovine Viral Diarrhea Virus Vaccine. Vet Diagn Invest. Accepted November 2010

Corbett E, Grooms D, Bolin S. Evaluation of skin samples by RT-PCR following immunization with a modified-live Bovine Viral Diarrhea Virus vaccine. Proceedings of the 2010 Conference of Research Workers in Animal Diseases, Chicago, IL, December 5-7, 2010, Abstract # 157.

da Silva L, Gadreault N, Jones C. 2011. Cytoplasmic localized infected cell protein 0(pICP00 encoded by bovine herpesvirus 1 inhibits beta interferon promoter activity and reduces IRF3 protein levels. Virus Res: In press.

da Silva L, Jones C. 2011. Infection of cultured bovine cells with bovine herpesvirus1 (BHV-1) or Sendai virus induces different beta interferon subtypes. Virus Res 157:54-60.

Fulton RW, Step DL, Wahrmund J, Burge LJ, Payton ME, Cook BJ, Burken D, Confer AW. Bovine coronavirus infections in transported commingled beef cattle and sole source ranch calves. Can J Vet Res 75: 191-199, 2010.

Fulton, R.W., Step, D.L., Wahrmund, J., Burge, L.J., Eberle, R., dOffay J.M., Confer A.W., Cook, B.J., Burken, D., Richards, C., Payton, M.E.: Bovine Coronavirus Infections in Transported Commingled Beef Cattle and Sole Source Ranch Calves. American Association of Bovine Practitioners Proceedings. August 19-21, 2010. Albuquerque, NM..

Fulton, R.W., dOffay J.M., Burge L.J., Eberle R., McCormack, K., Step D.L., Wahrmund J., Holland B.: Bovine Herpesvirus-1: Molecular Studies of Isolates from Clinical Cases Characterizing Field Isolates and Vaccine Strains. 53rd Annual Meeting of AAVLD, November 11-17, 2010. Minneapolis, MN.

Fulton, R.W., Confer, A.W., Joint Presentation. Gold Standards for Bovine Respiratory Diagnosis, Do They Exist? Laboratory Tests, the Good, the Bad, the Ugly. Academy of Veterinary Consultants Meeting, March 31-April 2, 2011, Oklahoma City, OK.


Gaudreault N and Jones C. 2011. Regulation of promyelocytic leukemia (PML) protein levels and cell morphology by bovine herpesvirus 1 infected cell protein 0 (bICP0) and mutant bICP0 proteins that do not localize to the nucleus. Virus Res 156:17-24.

Geertsema RS, Zekarias B, La Franco Scheuch L, Worby C, Russo R, Gershwin LJ, Herdman DS, Lo K, Corbeil LB. IbpA DR2 subunit immunization protects calves against Histophilus somni pneumonia. Vaccine. 2011 Jun 24;29(29-30):4805-12. Epub 2011 May 8.

Gershwin LJ, Anderson ML, Wang C, Berghaus LJ, Kenny TP, Gunther RA. Assessment of IgE response and cytokine gene expression in pulmonary efferent lymph collected after ovalbumin inhalation during experimental infection of calves with bovine respiratory syncytial virus. Am J Vet Res. 2011 Jan;72(1):134-45.
G. Hanzlicek, B.J. White, D. Renter , D. Anderson, R. Larson. Association between the prevalence of Mollicutes and Mycoplasma bovis and health and performance in stocker calves. Vet. Rec. 2011, 168(1):21. Epub 2010 Dec. 17.

G.A. Hanzlicek, B.J. White, D.G. Renter, D. Blasi. A field study evaluating health, performance, and behavior differences in crossbred beef calves administered different vaccine-parasiticide product combinations. Vaccine. 2010, Aug. 28(37):5998-6005. Epub 2010 July 14.

G. Hanzlicek, D. Renter, B.J. White, B.A. Wagner, D.A. Dargatz, M.W. Sanderson, H.M. Scott, R. Larson. Management practices associated with the rate of pre-weaning calf respiratory disease: results from a national survey of U.S. cow-calf operations. American Association of Bovine Practitioners Annual Conference, St. Louis, MO. September 2011.

Kisiela DI, Aulik NA, Atapattu DN, CZUPRYNSKI, CJ. 2010. N-terminal region of Mannheimia haemolytica leukotoxin serves as a mitochondrial targeting signal in mammalian cells. Cell. Microbiol. 12:976-987.

Krunkosky TM, B. Heins, L. Berghaus, M. Ard, C. Jarrett, A. Woolums.. Morphology of Primary Bovine Bronchial Cultures from Live Calves and Cellular Responses to Bovine Respiratory Syncytial Virus. Am J Resp Crit Care Med. 181:B182, 2010.

Kumar, R., B. Nanduri, J. Watt, A. Cooksey, and M. L. Lawrence. 2010. High throughput transcript mapping of Histophilus somni 2336 by deep sequencing. Conference for Research Workers in Animal Disease, Chicago, Illinois.

Lee, N., Rosenbusch, R. F. Characterization of an ATP-binding cassette transport system responsible for nucleoside uptake in Mycoplasma bovis. Poster G-1271, 110th General Meeting of the American Society for Microbiology, San Diego, CA, 2010.

Leyh, R.D., Fulton, R.W., Stegner, J.E., Goodyear, M., Witte, S., Taylor, L.P., Johnson, B.J., Step, D.L., Ridpath, J.F., Holland, B.P.: Fetal Protection in Heifers Vaccinated with a Modified Live Virus Vaccine Containing Bovine Viral Diarrhea Virus Subtypes BVDV1a and BVDV2a and Exposed During Gestation to Cattle Persistently Infected with BVDV Subtype 1b. American Journal for Veterinary Research 72: 367-375, 2011.

Morarie, S. Mediger J, Braun L, Chase C, Smirnova N, Hansen T. Fetal immunological effects and liver tolerance following persistent bovine viral diarrhea virus infection. Abstract 126P. 91st annual meeting of Conference of Research Workers in Animal Disease, Chicago, IL, December 5-7, 2010.


Neill J, Schefers J, Chase C, Ridpath J. Vaccination of cattle persistently infected with BVDV does not cause a change in the consensus sequence of the structural proteins of the viral quasispecies. 53rd Annual Joint Meeting American Association of Veterinary Laboratory Diagnosticians (AAVLD)/United States Animal Health Association (USAHA). November 11-17, 2010, Minneapolis, MN

Panciera RJ, Confer AW. Pathogenesis and pathology of bovine pneumonia. Vet Clin North Amer Food Anim Prac 26: 191-214, 2010

Pinchuk, L., Ammari, M., McCarthy, F., Nanduri, B. 2010. Proteomic analysis of Bovine Viral Diarrhea Virus-infected monocytes. December 2010, CRWAD

Rose-Dye TK, Burciaga-Robles LO, Krehbiel CR, Step DL, Fulton RW, Confer AW, Richards CJ. Rumen temperature change monitored with remote reporting rumen temperature boluses following challenges with Bovine Viral Diarrhea Virus and Mannheimia haemolytica. J Animal Sci 89: 1193-1200, 2011.

Rosenbusch, R. F. Influx transporters and Mycoplasma bovis colonization and virulence.
Invited presentation at the Symposium on Pathogenic attributes of animal mycoplasmas, 110th General Meeting of the American Society for Microbiology, San Diego, CA, 2010.

Singh K, Confer AW, Hope JC, Rizzi T, Wyckoff JH, Weng HY, Ritchey JW. Cytotoxicity and cytokine production by bovine alveolar macrophages challenged with wild type and leukotoxin-deficient Mannheimia haemolytica. The Vet J 188: 221-227, 2011

Singh K, Ritchey JW, Confer AW. Mannheimia haemolytica: Bacterial-host interactions in bovine pneumonia. Vet Pathol 48:338  348, 2011

Sanders, W. S., N. Wang, S. M. Bridges, B. M. Malone, Y. S. Dandass, F. M. McCarthy, B. Nanduri, M. L. Lawrence, and S. C. Burgess. 2011. The Proteogenomic Mapping Pipeline Tool. BMC Bioinformatics 12(1):115.

Sinani D, Jones C. 2011. Localization of sequences in a protein encoded by the latency related gene of bovine herpesvirus 1 (ORF2) that inhibits apoptosis and interferes with Notch 1 mediated trans-activation of the bICP0 promoter. J Virol: In press.

Stevens ET, MS Brown, WW Burdett, MW Bolton, ST Nordstrom CCL Chase. 2011. Efficacy of a non-adjuvanted, modified-live virus vaccination in calves with maternal antibodies against a virulent bovine viral diarrhea virus type 2 challenge seven months following vaccination. The Bovine Practitioner 45:23-31.
Taylor JD, Fulton RW, Lehenbauer TW, Step DL, Confer AW. The epidemiology of bovine respiratory disease: What is the evidence for predisposing factors? Can Vet J 51: 1095-1102, 2010.

Taylor JD, Fulton RW, Lehenbauer TW, Step DL, Confer AW. The epidemiology of bovine respiratory disease: What is the evidence for preventive measures? Can Vet J 51: 1351-1359, 2010

M.E. Theurer, D.E. Anderson, B.J. White, M.D. Miesner. Physiological and behavioral changes with variations in ambient temperature and exposure to lipopolysaccharides in cattle. American Association of Bovine Practitioners Annual Conference, St. Louis, MO. September 2011.

B.J. White, G. Hanzlicek, M.W. Sanderson, D.E. Anderson, R.L. Larson. Mollicutes species and Mycoplasma bovis prevalence and association with health outcomes in beef feeder calves at arrival and initial treatment for bovine respiratory disease. Can Vet J. 2010, Sept. 51(9):1016-1018.

B.J.White, D.E. Anderson, D.G. Renter, R.L. Larson, D. Mosier, L. Kelly, M. Theurer, B. Robért, M. Walz. Clinical, behavioral, and pulmonary changes following Mycoplasma bovis challenge in calves. Am J Vet Res , In press.

Workman A, Sinani D, Pittayakhajonwut D, Jones C. 2011. A protein (ORF20 encoded by the latency related gene of bovine herpesvirus 1 interacts with Notch 1 and Notch 3. J Viorol 85:2536-2546.