09/20/2001

Brogden, K.A., Kalfa, V.C., Ackermann, M.R., Palmquist, D.E., McCray, P.B., Jr., and Tack, B.F. The ovine cathelicidin SMAP29 kills ovine respiratory pathogens in vitro and in an ovine model of pulmonary infection. Antimicrob. Agents Chemother 45:331-334, 2001.



Butler, J.A., C.C. Pinnow, J.U. Thomson, S. Levisohn, and R.F. Rosenbusch. 2001. Use of arbitrarily primed polymerase chain reaction to investigate Mycoplasma bovis outbreaks. Vet Microbiol. 78: 175-181.





Caverly, J.M., Radi, Z.A., Andreasen, C.B., Doxon, R.A., Brogden, K.A., and Ackermann, M.R. Comparison of bronchoalveolar lavage fluid obtained from Mannheimia haemolytica-inoculated calves with and without prior treatment with the selection inhibitor TBC1269. Am. J. vet. Res. 62:665-672, 2001.





Chapes S.K., Mosier D.A., Wright A.D., Hart M.L.: MHCII, T1r4, Nramp1 genes control host pulmonary resistance against the opportunistic bacterium Pasteurella pneumotropica. J. Leukocytes Biol., 69:381-386, 2001.





Clarke, J.M., Morton, R.J., Clarke, C.R., Fulton, R.W., Saliki, J.T., and Malayer, J.: Development of an ex vivo Model to study Adherence of Mannheimia haemolytica serovar A1 to Mucosal Tissues of the Upper Respiratory Tract of Cattle. Am. J. Vet. Res., 62:805-811, 2001.





Confer AW, Suckow MA, Montelongo M, Dabo SM, Miloscio LJ, Gillespie AJ, and GL Meredith. Intranasal vaccination of rabbits with Pasteurella multocida A:3 outer membranes expressing iron-regulated proteins. Am J Vet Res 62:697-703, 2001..







Hegde, N.R., Godson, D.L., Babiuk, L.A. and Srikumaran, S. 2001. Bovine lymphocyte antigen-A11-specific peptide motif as a means to identify cytotoxic T lymphocyte epitopes of bovine herpesvirus 1. Cellular Immunology, Submitted.







Hinkley S, AB Hill, and S Srikumaran. 2001. Bovine herpesvirus 1 infection affects the peptide transport activity of TAP in bovine cells. Virus Res. Submitted.



Hossain A, T Holt, and C Jones. 2001. Analysis of cyclins and cyclin dependent kinases after an infection with herpes simplex virus type 2. J Gen Virol. In press.





Inman, M., Y. Zhange, V. Geiser, and C. Jones. 2001. The zinc ring finger of bovne herpes virus 1 encoded biCPO is necessary for transcriptional regulation and infection. J. Gen. Virology 82:483-492.







Jeyaseelan, S., M.S. Kannan, S.L. Hsuan, A.K. Singh, T.F. Walseth, and S.K. Maheswaran. 2001. Pasteurella haemolytica leukotoxin-induced cytolysis of bovine leukocytes: Role of arachidonic acid and its regulation. Microb. Pathog. 30:59-69.







Kalfa V.C. Palmquist, D., Ackermann, M.R., and Brogden, K.A. (2001). Suppression of Mannheimia (Pasteurella) haemolytica serovar 1 infection in lambs by intrapulmonary administration of ovine antimicrobial anionic peptide. Int J Antimicrob Agents. 17:505-10.







Kirkpatrick, J., Fulton, R.W., Burge, L.J., Dubois, W.R., and Payton, M. 2001): Passively Transferred Immunity in Newborn Calves, Antibody Decay, and Effect on Subsequent Vaccination with Modified Live Virus Vaccine. Bovine Practitioner, 35:47-55.







Loan RW, Purdy CW, Briggs RE: Additive effect of antibiotic metaphylaxis and Pasteurella haemolytica bacterin vaccination. In revision for the Bovine Practitioner, June, 2001.





Loughmiller J.A., spire M.F., Dritz S.S., Fenwick B.W., Hosni M.H., Hogge S.B.: Relationship between mean body surface temperature measured by use of infrared thermography and ambient temperature in clinically normal pigs and pigs inoculated with Actinobacillus pleuropneumoniae. Am. J. Vet. Res., 62:676-681, 2001.





Malazdrewich, C., T.R. Ames, M.S. Abrahamsen, and S.K. Maheswaran. 2001. Pulmonary expression of tumor necrosis factor-alpha, interleukin-beta, and interleukin-8 in the acute phase of bovine pneumonic pasteurellosis. Vet. Pathol. 38:297-310.







Navaratnam, M., M. Desphande, M.J. Hariharan, D.S. Zatechka Jr. and S. Srikumaran. 2001. Heat shock protein-peptide complexes elicit cytotoxic T-lymphocyte and antibody responses specific for bovine herpesvirus 1. Vaccine. 19:1425-1434.





Radi, Z.A., Caverly, J.M., Dixon, R.A., Brogden, K.A., and Ackermann, M.R. (2001) Effects of the synthetic selectin inhibitor TBC1269 on tissue damage during acute Mannheimia haemolytica-induced pneumonia in neonatal calves. Am. J. Vet. Res. 62:2684-2691.







Salih, B.A., and R.F. Rosenbusch. 2001. Cross-reactive proteins among eight bovine mycoplasmas detected by monoclonal antibodies. Comp. Immunol. Microbiol. Infect. Dis. 24:103-111.







Sylte, M.J., L. B. Corbeill, and C.J. Czuprynski. 2001. Haemophilus somnus causes apoptosis in bovine endothelial cells in vitro. Infect. Immun. 69:1650-1660.







Wittum, T.E., D. M. Grotelueschen, K.V. Brock, W. Kvasnicka, J. Floyd, C.L. Kelling and K.G. Odde. 2001. Persistent bovine viral diarrhea virus infection in beef herds. Veterinary Preventive Medicine 49:83-84.





Zhao, C., Nguyen, T., Lui, L., Sacco, R.E., Brogden, K.A., and Lehrer, R.I. Gallinacin-3, an inducible epithelial beta-defensin in the chicken. Infect. Immun. 69:2684-2691, 2001.





Zheng L, Swanson M, Liao J, Wood C, Kapil S, Snider R, Loughin T, and H Minocha. 2001. Cloning of the Bovine Immunodeficiency Virus Gag Gene and Development of a Recombinant-Protein Based Enzyme-Linked Immunosorbent Assay. Clin Diag Lab Immunol 7:557-562.





Zheng, L., Zhang S., Wood C., Kapil S., Wilcox G., Loughin T., Minocha H.: Differentiation of two bovine Lentiviruses by a monoclonal antibody on the basis of epitope specificity. Clin. Diagn. Lab. Immunol. 3:283-287, 2001.

09/26/2002

Akula S, DJ Hurley, RL Wixon, C Wang and CCL Chase. 2002. Effect of genistein on replication of bovine herpesvirus type 1. Am. J. Vet. Res.63:1124-1128.





Ambagala AP, Z. Feng, RG, Barletta, S. Srikumaran. 2002. Molecular cloning, sequencing, and characterization of bovine transporter associated with antigen processing 2 (BoTAP2). Immunogenetics 54:30-38.





Brock KV, Cortese VS. Experimental fetal challenge using type II bovine diarrhea virus in cattle vaccinated with a modified-live virus vaccine. Vet therapeutics 2001;2:354-360.





Butler JA, CC Pinnow, JU Thomson, S. Levisohn, RF Rosenbusch.

2001. Use of arbitrarily primed polymerase chain reaction to investigate

Mycoplasma bovis outbreaks. Vet. Microbiol. 78: 175-181.





Champlin FR, TR Shryock, CE Patterson, FW Austin, PE Ryals. 2002. Prevalence of a novel capsule-associated lipoprotein among Pasteurellaceae pathogenic in animals. Curr. Microbiol. 44:297-301.





Chouljenko VN, XQ Lin, J Storz, KG Kousoulas, 2001. Elucidation of the genomic nucleotide sequence of bovine coronavirus and analysis of cryptic leader mRNA fusion sites. Adv. Exp. Med. Biol. 2002. 494:49-55.





Chouljenko VN, Lin XQ, Storz J, Kousoulas KG, Gorbalenya AE. 2001. Comparsion of genomic and predicted amino acid sequences of respiratory and enteric bovine coronaviruses isolated from the same animal with fatal shipping pneumonia. J Gen Virol 82:2927-2933.





Chowdhury SI, Onderci M, Bhattacharjee PS, Al-Mubarak A, Weiss ML, Zhou Y. (2002). Bovine herpesvirus 5 (BHV-5) Us9 is essential for BHV-5 neuropathogenesis. J. Virol. 76: 3839- 3851.





Confer AW, Suckow MA, Montelongo M, Dabo SM, Miloscio LJ, Gillespie AJ, Meredith GL. Intranasal vaccination of rabbits with Pasteurella multocida A:3 outer membranes expressing iron-regulated proteins. Amer J Vet Res 62:697-703, 2001.





Confer AW, Montelongo M, Brown MJ, Fergen BJ, Clement JC. Onset of Serum Antibodies to Pasteurella (Mannheimia) haemolytica following vaccination with five commercial vaccines. Bov Practitioner 35: 141-148, 2001.





DeBey BM, Lehmkuhl HD, Chard?Bergstrom C, Hobbs LA. Ovine adenovirus serotype 7?associated mortality in lambs in the US. Vet. Pathol. 2001:38 644?648.





Fales-Williams AJ, Gallup JM, Ramirez-Romero R, Brogden K., Ackermann MR. Increased anionic peptide distribution and intensity during progression and resolution of bacterial pneumonia. Clin. Diagn. Lab. Immunol. 2002:1, 28-32.





Fent GM, Fulton RW, Saliki JT, Caseltine SL, Lehmkuhl HD, Confer AW, Purdy CW, Briggs RE, Loan RW, Duff GC. Bovine adenovirus-7 infections in postweaning calves. Am. J. Vet. Res. 63:976-978, 2002.





Flores EF, GR Risatti, et al. (2002). Expression of the mouse Fc receptor B2 in bovine cells rescues the infectivity of conditionally neutralized bovine viral diarrhea virus. Vet. Microbiol. 85: 99-109.





Frank GH, Briggs RE, Duff GC, Loan RW, Purdy CW. Effects of pretransit vaccination and arrival medication with florfenicol on the health of transported calves and the presence of Mannheimia haemolytica organisms in nasal secretions. Am. J. Vet. Res. 2002: 63, 251?256.





Frazier M, Pence M, Mauel MJ, Ligget A, Hines ME, Sangster L, Lehmkuhl HD, Miller D, Styer E, West J, Baldwin CA. Endometritis in postparturient cattle associated with bovine herpesvirus?4 infection: 15 cases. J. Diagnos. Invest. 2001: 13, 502?508.





Fulton RW, Cook BJ, Step DL, Confer AW, Saliki JT, Burge LJ, Welsh RD, Blood KS, Payton MD. Evaluation of animal health status of calves and their impact on feedot performance: Assessment of a retained ownership program of postweaning calves. Can. J. Vet. Res. 66:173-180, 2002.





Fulton RW, Ridpath JF, Saliki JT, Briggs RE, Confer AW, Burge LT, Purdy CW, Loan RW, Duff GC, Payton ME. Bovine viral diarrhea virus (BVDV)1b: Predominant subtype in calves with respiratory disease. Can. J. Vet. Res. 66:181-190, 2002.





Gatto NT, Dabo SM, Hancock RE, Confer AW. Characterization of, and immune responses of mice to, the purified OmpA-equivalent outer membrane protein of Pasteurella multocida serotype A:3 (Omp28),. Vet Microbiol 87:221-235, 2002.





Givens MD, Galik PK, Riddell KP, Stringfellow DA, Brock KV, Bishop MD, Eilertsen KJ, Loskutoff NM. Validation of a reverse transcription nested polymerase chain reaction (RTnPCR) to detect bovine virus diarrhea virus (BVDV) associated with in vitro-derived bovine embryos and co-cultured cells. Theriogenology 2001;56:787-799.





Grooms DL, Kaiser L, Walz PH, Baker JC. Study of cattle persistently infected with bovine viral diarrhea virus that lack detectable virus in their serum. J Am Vet Med Assoc, 2001;219:629-631.





Grooms DL, Coe PH. Antibody response following vaccination for respiratory viruses in preconditioned calves. Vet. Therap. 3;119-127





Grooms DL, Keilan E. Screening of neonatal calves for bovine viral diarrhea virus by immunohistochemistry on skin samples. Clin Diagn Lab Immun, 9:898-900. 2002





Guey-Chuen P, B. Maguen, L. Jing, K.R. Mott, N. Osorio, S.M. Slanina, A. Yukht, H. Ghiasi, A.B. Nesburn, M. Inman, G. Henderson, C. Jones, and S.L. Wechsler. 2002. A gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 LAT gene and restore wild type reactivation levels. J. Virol. 76:1224-1235.





Hart ML, Mosier DA, Chapes SK.: The response of Tlr-4-receptor positive cells to infection. 35th Annu. Soc. for Leuk. Biol., Honolulu, HI, 2001. J. Leukocyte Biol. supp., 67, 2001.





Inman M, Y. Zhange, V. Geiser, and C. Jones. 2001. The zinc ring finger of bovine herpes virus 1 encoded bICP0 is necessary for transcriptional regulation and infection. J. Gen. Virol. 82:483-492.





Inman M, L Lovato, A. Doster, and C. Jones. 2001. A mutation in the latency related gene of bovine herpesvirus 1 leads to impaired ocular shedding in acutely infected calves. J. Virol. 75:8507-8515.





Jeyaseelan,S., M.S. Kannan, R. E. Briggs, P. Thumbikat, and S. K. Maheswaran. 2001. Mannheimia haemolytica leukotoxin activates a non-receptor tyrosine kinase-signaling cascade in bovine leukocytes which induces biological activity. Infect. Immun. 69: 6131-6139.





Jeyaseelan S, MS Kannan, SL Hsuan, AK Singh, TF Walseth, S.K.Maheswaran. 2001. Pasterella haemolytica leukotoxin - induced cytolysis of bovine leukocytes: Role of arachidonic acid and its regulation. Microb. Pathog. 30: 59-69.





Kalfa VC, Jia HP, Kunkle RA, McCray Jr. PB, Tack BF, Brogden KA. Congeners of SMAP29 kill ovine pathogens and induce ultrastructural damage in bacterial cells. Antimicrob. Agents Chemother. 45:3256-3261, 2001.





Lafleur RL,C. Malazdrewich, S Jeyaseelan, E Bleifield, MS Abrahamsen, SK Maheswaran. 2001. Lipopolysaccharide enhances cytotolysis and inflammatory cytokine induction in bovine alveolar macrophages exposed to Pasteurella (Mannheimia) haemolytica leukotoxin. Microb. Pathog. 30: 347-357.





Leite F, M. Sylte, S O‘Brien, R Schultz, S Peek, K. Van Reeth and C. Czuprynski 2001. Effect of experimental infection of cattle with bovine herpesvirus-1 on the ex vivo interaction of bovine leukocytes with Mannheimia haemolytica leukotoxin. Vet. Immunol. Immunopathol. 84: 97-110.





Leite F, S O‘Brien, MJ Sylte, T Page, D Atapattu, and CJ Czuprynski. 2002. Inflammatory cytokines enhance the interaction of Mannheimia haemolytica leukotoxin with bovine peripheral blood neutrophils in vitro. Infect. Immun. 70:4336-4343.





Malazdrewich C, TR Ames, MS Abrahamsen, SK Maheswaran. 2001. Pulmonary expression of tumor necrosis factor - alpha, interleukin - beta, and interleukin - 8 in the acute phase of bovine pneumonic pasteurellosis. Vet. Pathol.38: 297-310.





McVicker JK, Tatatabai LB. The isolation of immunogenic outer membrane proteins from Pasteurella (mannheimia) haemolytica A1 using selective extraction and immunoaffinity chromatography techniques. Am. J. Vet. Res. (in press).





Pillars RA, Grooms DL. Serological evaluation of five unvaccinated heifers for detecting herds persistently infected with bovine viral diarrhea virus, Am J Vet Res, 2002; 63: 499-5.





Ramirez-Romero R, Brogden KA, Gallup JM, Sonea IM, Ackermann, MR. Mast cell density and substance P-like immunoreactivity during the initiation and progression of lung lesions in ovine Mannheimia (Pasteurella) haemolytica pneumonia. Microb. Pathogen. 2001; 30; 325-335.





Vanden Bush TJ, RF Rosenbusch. 2002. Mycoplasma bovis induces apoptosis of bovine lymphocytes. FEMS Immunol. Med. Microbiol. 32: 97-103.





Walz PH, Bell TH, Wells J, Grooms DL, Kaiser L, Maes RK, Baker JC. Relationship between level of viremia and disease manifestations in calves experimentally infected with bovine viral diarrhea virus. Am J Vet Res, 2001; 62: 1095-1103.





Walz PH, Bell TH, Wells J, Grooms DL, Kaiser L, Maes RK, Baker JC. Platelet aggregation responses and virus isolation from platelets in calves experimentally infected with type I or type II bovine viral diarrhea virus. Can J Vet Res, 2001; 65:241-247.





Wang P, DJ Hurley LJ, Braun, CCL Chase. 2001. Detection of bovine herpesvirus 1 in peripheral blood mononuclear cells 8 months post infection. J. Vet. Diag. Invest, 13:424-427.





Ward ACS, Weiser GC, Delong WJ, Frank GH. Characterization of Pasteurella spp isolated from healthy domestic pack goats and evaluation of the effects of a commercial Pasteurella vaccine. Am. J. Vet. Res. 2002: 63: 119?123.





Winkler MTC, A Doster, J-H Sur, C Jones. 2002. Analysis of bovine trigeminal ganglia following infection with bovine herpesvirus 1. Vet. Microbiol. 86:139-155.





Wittum TE, Groteueschen DM, Brock KV, Kvasnicka WG, Floyd JG, Kelling CL, Odde KG. Persistent bovine viral diarrhea virus infection in U.S. beef herds. Vet Prev Med 2001;49:83-94.





Zhang Y, C Jones. 2001. The bovine herpes virus 1 immediate early protein (bICP0) is associated with histone deaetylase 1 to activate transcription. 2001. J. Virology 75:9571-9578.

10/06/2003

Carter JN, Meredith GL, Montelongo M, Gill DR, Krehbiel CR, Payton ME, Confer AW. Relationship of vitamin E supplementation and antimicrobial treatment with acute-phase protein responses in cattle affected by naturally acquired respiratory tract disease. Am J Vet Res 63:1111-1117, 2002.





Caverly JM, Diamond G, Gallup JM, Brogden KA, Dixon RA, Ackermann MR. Coordinated expression of tracheal antimicrobial peptide and inflammatory-response elements in the lungs of neonatal calves with acute bacterial pneumonia.

Infect Immun. 2003 May;71(5):2950-5.





Chen, L., D. B. Paulsen, D. W. Scruggs, M. M. Banes, B. Y. Reeks, and M. L. Lawrence.

2003. Alteration of DNA adenine methylase (Dam) activity in Pasteurella multocida

causes increased spontaneous mutation frequency and attenuation in mice. Microbiology.

In press.





Chase CCL, SK Chase and L Fawcett. 2003. Trends in the BVDV Serological Response in the United States Upper Midwest Region. Biologicals 31:145-151.





Chirase NK, Purdy CW, Avampato JM. Effect of simulated ambient particulate matter exposure on performance, rectal temperature and leukocytosis of young Spanish goats with or without tilmicosin phosphate. J An Sci. Accepted May 2003.





Cudd LA, Clarke CR, Clinkenbeard KD. Mannheimia haemolytica leukotoxin-induced increase in leukotriene B4 production by bovine neutrophils is mediated by sustained and excessive increase in intracellular calcium concentration. Accepted for publication by FEMS Micro. Let.





Confer AW, Ayalew S, Montelongo M, Panciera RJ, Whitworth LC, Hammer, JD. Immunogenicity of Mannheimia haemolytica serotype 1 recombinant outer membrane protein PlpE and augmentation of a commercial vaccine. Vaccine 21: 2821-2829: 2003





Dabo SM, Confer AW, Quijano-Blas RA. Molecular and immunological characterization of Pasteurella multocida A:3 OmpA: Evidence of its role in P. multocida interaction with extracellular matrix molecules. Microb Pathog, in press





S.M. Dabo, A.W. Confer, and R.A. Quijano-Blas: Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078-2007. Molecular and immunological characterization of Pasteurella multocida serotype A:3 OmpA: Evidence of its role in P. multocida interaction with extracellular matrix molecules. Bacterial Pathogenesis, in press, 2003.





Deshpande, M., T.C. Ambagala, A.P.N., Ambagala, and S. Srikumaran. 2002. Bovine CD18 is necessary and sufficient to mediate Mannheimia (Pasteurella) haemolytica leukotoxin induced cytolysis. Infection and Immunity, 70:5058 5064.





Fairbanks K, J Schnackel, and CCL Chase. 2003. Evaluation of a modified live virus type 1a bovine virus diarrhea vaccine (Singer strain) against a type 2 890 (Strain 890) challenge. Vet.Therapeutics 4:24-34.





Evermann JF, Ridpath JF. Clinical and epidemiologic observations of bovine viral diarrhea virus in the northwestern United States. Vet Microbiol. 2002 Oct 22;89(2-3):129-39.





Fajt VR, Apley MD, Roth JA, Frank DE, Brogden KA, Skogerboe TL, Shostrom VK, Chin YL. The effects of danofloxacin and tilmicosin on neutrophil function and lung consolidation in beef heifer calves with induced Pasteurella (Mannheimia) haemolytica pneumonia. J Vet Pharmacol Ther. 2003 Jun;26(3):173-9.





Frank GH, Briggs RE, Duff GC, Hurd HS. Effect of intranasal exposure to leukotoxin-deficient Mannheimia haemolytica at the time of arrival at the feedyard on subsequent isolation of M haemolytica from nasal secretions of calves. Am J Vet Res. 2003 May;64(5):580-5.





Fulton RW, Step DL, Ridpath JF, Saliki JT, Confer AW, Johnson BJ, Briggs RE, Hawley RV, Burge LJ, Payton ME. Response of calves persistently infected with noncytopathic bovine viral diarrhea virus (BVDV) subtype 1b after vaccination with heterologous BVDV strains in modified live virus vaccines and Mannheimia haemolytica bacterin-toxoid. Vaccine. 2003 Jun 20;21(21-22):2980-5.





Fulton RW, Ridpath JF, Confer AW, Saliki JT, Burge LG, Payton ME. Bovine viral diarrhoea virus antigenic diversity: impact on disease and vaccination programmes. Biologicals. 2003 Jun;31(2):89-95.





Fulton, R.W., Saliki, J.T., Burge, L.J., and Payton, M.: Humoral Immune Response and Assessment of Vaccine Virus Shedding in Calves Receiving Modified Live Virus Vaccines Containing Bovine Herpesvirus-1 and Bovine Viral Diarrhea Virus 1a. Journal of Veterinary Medicine B, 50:31-37, 2003.





Fulton, R.W., Ridpath, J.F., Confer, A.W., Saliki, J.T., Burge, L.J., and Payton, M.E.: Bovine Viral Diarrhoea Virus Antigenic Diversity: Impact on Disease and Vaccination Programmes. Biologicals, 31:89-95, 2003.





Fulton, R.W., Step, D.L., Ridpath, J.F., Saliki, J.T., Confer, A.W., Johnson, B.J., Briggs, R.E., Hawley, R.V., Burge, L.J., and Payton, M.E.: Response of Calves Persistently Infected with Noncytopathic Bovine Viral Diarrhea Virus (BVDV) Subtype 1 b after Vaccination with Heterologous BVDV Strains in Modified Live Virus Vaccines and Mannheimia haemolytica Bacterin-Toxoid. Vaccine, 21:2980-2985, 2003.





Gatto NT, Dabo SM, Hancock RE, Confer AW. Characterization of, and immune responses of mice to, the purified OmpA-equivalent outer membrane protein of Pasteurella multocida serotype A:3 (Omp28),. Vet Microbiol 87: 221-235, 2002





Geiser, G., Melissa Inman, Y. Zhang, and C. Jones. 2002. The latency related (LR) gene of bovine herpes virus 1 (BHV 1) can inhibit the ability of bICP0 to activate productive infection. J. of General Virology 83: 2965 2971.





Geiser, G., M. Inman, Y. Zhang, and C. Jones. 2002. The latency related (LR) gene of bovine herpes virus 1 (BHV 1) can inhibit the ability of bICP0 to activate productive infection. J. of General Virology 83: 2965 2971.





Geiser, V. and C. Jones. 2003. Stimulation of bovine herpesvirus 1 productive infection by the adenovirus E1A gene and the cellular transcription factor E2F4. J. of General Virology, 84:929 938.





Gopinath,R.S., A.P.N., Ambagala, S. Hinkley, and S. Srikumaran. 2002. Effects of virion host shut off activity of bovine herpesvirus 1 on MHC class I expression. Viral Immunology, 15: 595 608.





Grooms DL, Keilan E. Screening of neonatal calves for bovine viral diarrhea virus by immunohistochemistry on skin samples. Clin Diagn Lab Immun, 2002;9(4):898-9.





Harding, M. J., X. Cao, H. Shams, A.F. Johnson, V.B. Vassilev, L.H., D.W. Wheeler, D. Haines, G.J. Sibert, L.D. Nelson, M. Campos, M., R.O. Donis. (2002). Role of bovine viral diarrhea virus biotype in the establishment of fetal infections. Am J Vet Res 63(10), 1455 63.





Inman, M., L. lovato, A. doster, and C. jones. 2002. A mutation in the latency related gene of bovine herpesvirus 1 disrupts the latency reactivation cycle in calves. J. of Virology, 76:6771 6779.





Jeyaseelan, S., S. Srinand, and S.K.Maheswaran. 2002. Role of Mannheimia haemolytica leukotoxin in the pathogenesis of bovine pneumonic pasteurellosis. Animal Health Research Reviews. 3: 69-82.





Jones, C. Analysis of HSV 1 and BHV 1 1 latency. 2003. Clinical Microbiology Reviews. 16:79 95





Kelling, C.L., Steffen, D.J., Topliff, C.L., Eskridge, K.M., Donis, R.O., Higuchi, D.S. 2002. Comparative virulence of bovine viral diarrhea virus type II in experimentally inoculated six to nine month old calves. American Journal of Veterinary Research 63:1379 1384.





Kelling, C.L., D. J Steffen, V.L Cooper, D.S. Higuchi, K.M. Eskridge. 2002. Effect of acute bovine viral diarrhea virus alone, bovine rotavirus alone, or concurrent infection with both on enteric disease in gnotobiotic neonatal calves. American Journal of Veterinary Research. 63:1179 1186.





Lakritz J, Marsh AE, Cockrell M, Smith MF, Tyler JW. Characterization of gelatinases in bronchoalveolar lavage fluid and produced by alveolar macrophages isolated from healthy calves. Accepted, July 10, 2003; Am. J. Vet. Res.





Liang, D., I.F. Sainz, I.H. Ansari, L.H. Gil, V. Vassilev, and R.O. Donis (2003). The envelope glycoprotein E2 is a determinant of cell culture tropism in ruminant pestiviruses. J Gen Virol 84(Pt 5), 1269 74.





Leite FS, O!&Brien MJ, Sylte, et al. 2002. Inflammatory cytokines enhance the interaction of Mannheimia haemolytica leukotoxin with bovine peripheral blood neutrophils in vitro. Infect Immun 70:4336-4343.





Leite FS, Giles D, Atapattu, et al. 2003. Prior exposure to Mannheimia haemoloytica leukotoxin or LPS enhances Beta2-integrin expression by bovine neutrophils and augments leukotoxin cytotoxicity. Microb Pathogen 34:267-275.





Liebler-Tenorio EM, Ridpath JF, Neill JD. Lesions and tissue distribution of viral antigen in severe acute versus subclinical acute infection with BVDV2.

Biologicals. 2003 Jun;31(2):119-22.





Liebler-Tenorio EM, Ridpath JF, Neill JD. Distribution of viral antigen and development of lesions after experimental infection of calves with a BVDV 2 strain of low virulence. J Vet Diagn Invest. 2003 May;15(3):221-32.





Lovato, L., M. Inman, G. Henderson, A. Doster., and C. Jones, C. 2003. Infection of cattle with a bovine herpesvirus 1 (BHV 1) strain that contains a mutation in the latency related gene leads to increased apoptosis in trigeminal ganglia during the transition from acute infection to latency. J of Virology, 77:4848 4857.





Maheswaran, S.K., P. Thumbikat, and T. Dileepan. 2002. Current knowledge on pathogenesis of lung injury caused by Mannheimia haemolytica and Pasteurella multocida in the bovine. Recent Developments and Perspectives in Bovine Medicine. Pages 160-167.





Mott, K., N. Osorio, L. Jin, D. Brick, J. Naito, J. Cooper, G. Henderson, M. Inman, C. Jones, S. L. Wechsler, and G. C. Perng. 2003. The BHV 1 LR gene!&s ability to restore the high reactivation phenotype to an HSV 1 LAT null mutant appears to be due to its anti apoptosis function. Journal of General Virology, IN PRESS.





Pillars RA, Grooms DL. Serological evaluation of five unvaccinated heifers for detecting herds persistently infected with bovine viral diarrhea virus, Am J Vet Res, 2002;63(4):499-5.





Purdy CW, Straus DC, Chirase N, Ayers JR, Hoover MD. Effects of aerosolized dust in goats on lung clearance of Pasteurella and Mannheimia species. Curr Micro 46(3):174. 2003.





Risatti, G. R., D. Pomp, and R.O. Donis (2003). Patterns of cellular gene expression in cells infected with cytopathic or non cytopathic bovine viral diarrhea Virus. Animal Biotechnology 14(1), 31 49.





Sylte MJ, Leite FP, Kuckleburg, Et al. 2003. Haemophilus somnus lipooligosaccharide-mediated apoptosis of bovine endothelial cells is caspase-8 dependent. Microb Pathogen. In press.





Thumbikat, P., R.E. Briggs, M.S. Kannan, and S.K. Maheswaran. 2003. Biological effects of two genetically defined mutants of Mannheimia haemolytica. Microb. Pathog. 34: 217-226.





Thumbikat P, Briggs RE, Kannan MS, Maheswaran SK. Biological effects of two genetically defined leukotoxin mutants of Mannheimia haemolytica. Microb Pathog. 2003 May;34(5):217-26.





Vanden Bush T. J., and R. F. Rosenbusch. 2003. Characterization of the immune response to Mycoplasma bovis lung infection. Vet. Immunol. Immunopath. 94: 23-33.





Woolums AR, Brown C, Brown Jr JC, et al. Effects of a single intranasal dose of modified-live bovine respiratory syncytial virus vaccine on resistance to subsequent viral challenge in calves. Am J Vet Res. In press. 2003.





Woolums AR, Siger S, Johnson S, Gallo G, Conlon J. Rapid onset of protection following

vaccination of calves with multivalent vaccines containing modified-live or modified-live

and killed BHV-1 is associated with virus-specific interferon gamma production. Vaccine.

2003; 21: 1158-1164.





Purdy CW, Straus DC, Chirase N, Parker DB, Ayers JR, Hoover MD. Effects of aerosolized endotoxin in feedyard dust on weanling goats. Small Rum Res 446:133. 2002.





ABSTRACTS:



Blackwood ER, Ayalew S, Confer AW. Molecular and Immunological Analysis of Outer Membrane Protein PlpE from Mannheimia haemolytica serotypes 1, 2, and 6. 83th Annual Meeting of CRWAD, 93, St. Louis, MO, 2002.





Bolin SR. BVD: The old and the new. Proceedings of the Minnesota Dairy Health Conference, St. Paul Minnesota, May20, 2003. pp 14-17.





Brady, R.P., C.L. Topliff, C.L. Kelling. 2002. Analyses of plasmid DNA encoding the attachment glycoprotein of bovine respiratory syncytial virus. Conference of Research Workers in Animal Diseases Proceedings.





Braun, LJ, M Braunschmidt, N Arias, Regina Wixon, CY Wang and CCL Chase. Effect of genistein on bovine herpesvirus 1 and bovine viral diarrhea virus infections in vivo. 35th annual Conference of American Association of Bovine Practitioners, Rapid City, SD, September 26-28, 2002, p. 206.





Chase CCL, G Elmowalid and LJ Braun. Effect of bovine viral diarrhea virus on bovine macrophages inflammatory functions and surface marker expression in vitro. Abstract A-4. 9th National Symposium: Basic Aspects of Vaccines, Bethesda, MD, April 30-May 2, 2003.





Confer AW. Pathogenesis of Bovine Bacterial Pneumonia. Proceedings ACVIM Forum, Charlotte, NC. 2003





Confer AW. Appropriate Usage of Antibiotics for Disease Control. Proceedings 2003 ASAS/ADSA Midwestern Regional Meeting, Des Moines, IA, 2003





Dabo SM, Confer AW, Quijano-Blast, RA. Pasteurella multocida OmpA as a potential adherence factor. Proceedings 103rd Annual Meeting of American Society of Microbiology, Washington, DC. 2003





Dabo SM, Confer AW, Quijano-Blast, RA. Identification of Bartonella henselae fibronectin binding proteins. Proceedings 103rd Annual Meeting of American Society of Microbiology, Washington, DC. 2003





Dunn J, Kaneene JB, Grooms D, Bolin S, Bolin C, Bruning-Fann C. The effect of infection with Mycobacterium paratuberculosis on the reliability of the caudal fold tuberculin (CFT) test and the gamma-interferon test for bovine tuberculosis in cattle. Proceedings of the 83th Annual Meeting of The Conference of Research Workers in Animal Diseases, St. Louis, MO, November 11, 2002. Abstract # 47.





Elmowalid, G, BL Ransom, LJ Braun, A Young, J Ridpath and CCL Chase. Bovine viral diarrhea virus interferes with macrophage surface marker expression in vitro. Abstract 185. 83rd annual meeting of Conference of Research Workers in Animal Disease, St. Louis, MO, November 11-12, 2002.





Fulton, R.W., Step, D.L., Ridpath, J.F., Saliki, J.T., Confer, A.W., Johnson, B.J., Welsh, R.D., Burge, L.J., Hawley, R.V., and Payton, M.E.: Bovine Viral Diarrhea Virus (BVDV) Persistently Infected Calves: Response to Vaccinations and Diagnoses at Necropsy. 45th Annual Meeting of AAVLD, October 18-22, 2002. St. Louis, MO.





Fulton, R.W., Step, D.L., Ridpath, J.F., Saliki, J.T., Confer, A.W., Johnson, B.J., Welsh, R.D., Burge, L.J., Hawley, R.V., and Payton, M.E.: Bovine Viral Diarrhea Virus (BVDV) Infections of Calves after Exposure to Persistently Infected Calves with BVDV Subtype 1b. 45th Annual Meeting of AAVLD. October 18-22, 2002. St. Louis, MO.





Gopinath, R.S., T.C. Ambagala, A.P.N. Ambagala and S. Srikumaran. GP96 as an adjuvant for the induction of cytotoxic T lymphocytes (CTLs) specific for bovine herpesvirus 1 (BHV 1). International Herpesvirus Workshop. July 26 31, 2003.





Grooms DL, Brock KV, Norby B. Performance Of Feedlot Cattle Exposed To Animals Persistently Infected With Bovine Viral Diarrhea Virus. Proceedings of the 83th Annual Meeting of The Conference of Research Workers in Animal Diseases, St. Louis, MO, November 11, 2002. Abstract # 186





Hassan EAD, B Tigabu, LJ Braun and CCL Chase. Reorganization of microtubules and actin filaments in bovine herpesvirus-1-infected cells and their role in virion egress. Abstract p28-5. 22nd Annual Meeting of American Society for Virology, Davis, CA July 12-16, 2003.





Hassan, EAD, LJ Braun, and CCL Chase. The effect of bovine herpesvirus 1 (BHV-1) on the organization of actin filaments and microtubules. Abstract 116-P. 83rd annual meeting of Conference of Research Workers in Animal Disease, St. Louis, MO, November 11-12, 2002.





Hunsaker, B.D, C.L.Topliff, J.A. Achenbach, C.L.Kelling. 2002. Back passage of a commercial modified live vaccine (MLV) strain of type 1 noncytopathic bovine viral diarrhea virus did not result in reversion to virulence. Conference of Research Workers in Animal Diseases Proceedings.





Inman, M. and C. Jones, Identification and Characterization of a Novel Transcript containing an ORF that is expressed during latency, and is Antisense to the Latency Related Gene of BHV 1. International Herpesvirus Workshop. July 26 31, 2003.





Jiang, Y., M. Inman, Y. Zhang, and C. Jones. A mutation in the latency related gene of bovine herpesvirus 1 (BHV 1) inhibits expression of proteins encoded by ORF2 and Reading Frame C during productive infection. International Herpesvirus Workshop. July 26 31, 2003.





Lasarsky, E., Fulton, R.W., Confer, A.W., Saliki, J.T., Briggs, R.E., and Huchzermeier, R.: Bovine Coronavirus Infections in Cattle: Detection in Nasal Swabs by Antigen Capture ELISA and RT-PCR. CRWAD, November 10-12, 2002. St. Louis, MO.





Lin, K-f, McArthur-Vaughan, K., Rhodes, G.H., Gershwin, L.J. Evaluation of cDNA Vaccines Coding for F or N Proteins of Bovine Respiratory Syncytial Virus: Clinical Outcome and Immune Response. W43-12. American Society for Virology, 22nd Annual meeting, University of California, Davis. July 12-16, 2003.





Lu, X., and R. F. Rosenbusch. Mycoplasma bovis induces the up-regulation of VCAM-1 and ICAM-1 in bovine aortic endothelial cells. 83rd Annual Meeting of the Conference for Research Workers in Animal Disease, St. Louis, Poster 6P, 2002.





Maheswaran, S. K., C. Malazdrewich, and H.S. Yoo. 2002. The role of proinflammatory cytokines TNF-alpha, IL-1-beta, and IL-8 in pneumonic mannheimiosis. Proceedings 8th International Vet. Emergency and Critical Care Symposium, Pp 423-426. September 4-8,

San Antonio, Texas.





Maheswaran, S.K., and P. Thumbikat. 2002. Molecular characterization of the Mannheimia haemolytica leukotoxin receptor: Controversy and conundrums. Proc. 83rd Conf.Res. Workers Anim. Dis. Abst. No: 1.





Marsh, T and C Chase. Evaluation of alternate year vaccination practices in a cow-calf herd. 35th annual conference of American Association of Bovine Practitioners, Rapid City, SD, September 26-28, 2002, p. 172.





Miao C, Woolums AR, Brown C, Brown C, Brown Jr JC, Williams S, Zarlenga DS. Measurement of cytokine gene expression by RT-competitive PCR in BRSV vaccinated and infected calves. Proceedings of the Conference for Research Workers in Animal Disease (CRWAD), St. Louis MO, November 2002.





Mott, K.R., N. Osorio, L. Jin, D. Brick, J. Naito, J. Cooper, G. Henderson, M. Inman, C. Jones, S. L. Wechsler, and G. C. Perng. The BHV 1 LR gene‘s ability to restore the high reactivation phenotype to an HSV 1 LAT null mutant appears to be due to its anti apoptosis function. ARVO meeting (vision and ophthalmology meeting), May, 2003.





Prado ME, Dabo SM, Confer AW. Cloning and characterization of HasR gene homologue from Pasteurella multocida A:3. Proceedings of HAP2002, Banff, Alberta, Canada, 2002.





Thumbikat, P., T. Dileepan, and S.K. Maheswaran. 2003. The bovine LFA-1 domain plays a critical role in mediating target cell activation but not binding of Mannheimia haemolytica leukotoxin. 103rd General Meeting, American Society Microbiology, Abstract # E-101.





Topliff, C.L., S.K.Chon, R.O. Donis, K.M. Eskridge, C.L.Kelling. 2002. Translational Efficiencies of genotype 2 bovine viral diarrrhea virus field isolates using a T7 vaccinia virus expression system. Conference of Research Workers in Animal Diseases Proceedings.





Y. Zhang & C. Jones. The bovine herpes virus 1 (BHV 1) immediate early gene encodes a protein (bICP0) that inhibits p53 transcriptional activity by sequestering A histone acetyltransferase (p300). International Herpesvirus Workshop. July 26 31, 2003.









DISSERTATION AND THESES:



Elmowalid, Gamal. Unmasking the effect of bovine viral diarrhea virus on macrophage inflammatory functions. PhD Dissertation, South Dakota State University, 2002.





Arias, Nicolas. Analysis of Two Vaccination Programs in Dairy Cows and Their Impact on the Herd Performance and Colostrum Quality. Master of Science Thesis, South Dakota State University, 2003.





Miao, Congrong. Cytokine messenger RNA expression in calves vaccinated intranasally with modified-live bovine respiratory syncytial virus (BRSV) prior to BRSV challenge. Master of Science Thesis, University of Georgia, 2003.





Ransom, Brian. The Effect of Bovine Herpesvirus Type 1 or Type 4 on the Functional Characteristics of Monocyte-Derived Macrophages. Master of Science Thesis, South Dakota State University, 2003.

11/12/2004

FUNDING SUPPORT


Prevalence of mycoplasma infection in Georgia cattle. Woolums A, Sanchez S, Pence M, Cole D, Ensley D. Support from the University of Georgia College of Veterinary Medicine Food Animal Health Management Program. October 2002-June 2004. $10,000.


Preliminary prevalence study of Mycoplasma bovis and Mycoplasma sp. in selected Dairy and beef herds in Georgia. Giusto N, Woolums AR, Sanchez. Project for Georgia Veterinary Scholars Program participant Nicole Giusto, sophomore veterinary student.May-August 2003. Funded by the Merck Foundation andMerial Ltd. $5000.


Multidisciplinary evaluation of fatal feedlot ARDS. Woolums AR, principle investigator. Hawkins L, Brown C, Hungerford L, Loneragan G, Mason G, co-investigators. USDA National Research Initiative Competitive Grants Program. September 2000-August 2004. $240,000


Comparison of the capacity of in vitro tools to assess the immune response of cattle to inactivated and modified-live vaccines and their relationship to protection from infection and acute disease. Hurely, D.J, Woolums, A.R, Reber, A.J. and Okinaga, T.March. GRA- Merial LTD. 2003-December 2004. $181,000


The role of infectious agents in chronic respiratory diseases: (UGA)Hurley, D.J. (coordinator), Woolums, A., Moore, J.N., Krunkosky, T.M., Krause, D.Terry Respriatory Disease Fund. January 2003  December 2004. $76,000.


Interaction of H. somnus and purinoceptors, in apoptosis of endothelial cells. Czuprynski, Charles J. USDA NRI CGP. 07/01/00-06/30/04. $180,000


Cytokine-mediated enhancement of the susceptibility of bovine leukocytes to Pasteurella haemolytica leukotoxin. Czuprynski, Charles. WI Ag. Experiment Station 10/01/01-09/30/04. $87,000.


Evolving Pathogens, targeted sequences and strategies for control of bovine respiratory diseases. Czuprynski, Charles. WI Ag. Experiment Station 10/01/01-09/30/04. $66,000


Integrin-dependent signaling and exacerbation of the leukocyte response to Mannheimia haemolytica leukotoxin by virus infection and cytokines. Czuprynski, Charles. USDA NRICGP 07/01/04-06/30/07. $370,000.


Role of caspase-9 activation and mitochondria in Mannheimia haemolytica leukotoxin mediated apoptosis in bovine leukocytes. Czuprynski, Charles. WI Ag. Experiment Station 10/01/04-09/30/07. $88,000


Microvascular endothelial cell response to Haemophilus. Czuprynski, Charles. NIH K08. 12/01/03  11/30/07. $286,000.


Contrast in lung immune responses after chronic Mycoplasma bovis infection or vaccine-induced susceptibility. Ricardo F. Rosenbusch. USDA Formula Funds Oct 03Sep 04. $20,000


Immune-mediated lung damage in Mycoplasma bovis infection. Ricardo F. Rosenbusch. Healthy Livestock for Iowa. Jul 03  Jun 04. $19,996.


Testing a newly discovered peptide as a unique immunosuppressive agent. Ricardo F. Rosenbusch. Carver Trust. 16 Apr 03-31 Jul 04. $23,804.


Extracts of Mycoplasma bovis as antigens for vaccines. Ricardo F. Rosenbusch. Boehringer Ingelheim Vetmedica, Inc. Oct 00- Jun 04. $189,794.


Role ofgE and gI in BHV-1 and BHV-5 differential neuropathognesis. USDA NRI. Shafiqul I. Chowdhury 2001-2003. $285,000.


LPS induced lung inflammation: a model to characterize the role of matrix metalloproteinases in bovine respiratory disease. Lakritz J, Mattoon J, Abrahamsen E, Marsh AE, Weisbrode S. USDA CSREES 2004-2007 $350,000.


The role of dendritic cells in the bovine viral diarrhea virus antigen presentation. Pinchuk, LM. USDA/NRICGP Seed Grant. 2002-2003, $74,778.


Mannheimia haemolytica outer membrane protein PlpE: Characterization of epitopes stimulating homologous and heterologous serotype protection. Anthony Confer. USDA CSREES,National Research Initiative Competitive Grant. 2002-2005 (Grant # 2002-02232). $290,000


Chimeric Vaccine for Mannheimia haemolytica Infection in Cattle. Oklahoma Applied Research Program. Oklahoma Center for the Advancement of Science and Technology (OCAST). 2003-2005. $259,395.


Evaluation of Mannheimia haemolytica and Pasteurella multocida vaccines. Anthony Confer. Fort Dodge Animal Health, Inc. 2003-2005. $95,779.


The Production of mAb Using cDNA from E2 and Npro-C-Erns Region of Bovine Viral Diarrhea Virus (BVDV)
Vaccine 1b Isolate. Chris Chase. Novaritis Animal Health. 2003-2005. $23,9800.


Center for Infectious Disease and Vaccinology. State of South Dakota. Chris Chase. 6-04 to 5-09. $4,000,000.


Importance of Mycoplasma bovis in Michigan Feedlots. Dan Grooms. Michigan
Animal Industry Coalition. 2003-2004. $32,740,


Biosensor development for agrisecurity. Dan Grooms. Michigan Animal Industry Coalition. 2003-2004. $29,672.





PUBLICATIONS

PEER-REVIEWED MANUSCRIPTS:

Kalina WV, Woolums AR, Berghaus RD, Gershwin LJ. Formalin-inactivated bovine RSV vaccine enhances a Th2 mediated immune response in infected cattle. Vaccine 22 (11-12):1465-74. 2004


Donovan DC, AR Hippen, DJ Hurley and CCL Chase. 2003. The role of acidogenic diets and serum antibody response against bovine respiratory viruses in Holstein steers. J. Anim. Sci. 81:3088-3094.


Fogarty Fairbanks, K, J Campbell and CCL Chase. 2004. Rapid onset of protection against infectious bovine rhinotracheitis with a modified-live virus multivalent vaccine. Vet.Therapeutics 5:17-25.


Chase CCL, G Elmowalid and AAA Yousif. 2004. The immune response to bovine viral diarrhea virus: a constantly changing picture. Vet Clin Food Anim 20:95114.


Chase CCL, G Elmowalid, LJ Braun and JF Ridpath. New paradigms for bovine viral diarrhea virus: understanding how BVDV interacts with the immune system. 36th annual conference of American Association of Bovine Practitioners, Columbus, OH, September 18-20, 2003, p. 189.


Hassan EAD, LJ Braun and CCL Chase. Interaction of bovine herpesvirus-1 glycoproteins with cellular cytoskeletal elements in bovine herpesvirus-1 infected cells. Abstract 130P. 84th annual meeting of Conference of Research Workers in Animal Disease, Chicago, IL, November 9-11, 2003.


Hassan EAD, LJ Braun and CCL Chase. Effect of protein kinase inhibitors on the replication of bovine herpesvirus-1 (BHV-1). Abstract 174. 84th annual meeting of Conference of Research Workers in Animal Disease, Chicago, IL, November 9-11, 2003.


Miao C, Woolums AR, Zarlenga D, Brown C, Brown Jr JC, Williams S, Scott M. Effects of a single intranasal dose of modified-live bovine respiratory syncytial virus vaccine on cytokine messenger RNA expression following viral challenge in calves. Am J Vet Res. June 2004.


Woolums AR, Brown C, Brown Jr JC, Cole D, Scott M, Williams S, Miao C. Effects of a single intranasal dose of modified-live bovine respiratory syncytial virus vaccine on resistance to subsequent viral challenge in calves. Am J Vet Res. 2004; 65:363-372.


Vanden Bush T. J., and R. F. Rosenbusch. 2004. Characterization of a lympho-inhibitory peptide produced by Mycoplasma bovis. Bioch. Biophys. Res. Comm. 315: 336-341.


Al-Mubarak, A, Zhou, Y., and Chowdhury, S.I . (2004). A glycine rich region in the ecto domain of BHV-5 gE is important for BHV-5 neuropathogenesis. J. Virol. 78, 4806-4816.


Boudreaux, CM and Corstvet, RE. A novel strategy of controlling shipping fever. The Louisiana cattleman, Official publication of the Louisiana Cattlemens Association, November 2003, 36(11):10-11.


Bolin SR. Grooms DL. Origination and Consequences of Bovine Viral Diarrhea Virus Diarrhea Diversity. Vet Clin N Amer: Food An. 2004;20(1):51


Liu, D., M. L. Lawrence, and F. W. Austin. 2004. Specific PCR identification of
Pasteurella multocida based on putative transcriptional regulator genes. J.
Microbiol. Methods 58(2):263-267.


Jones, C. Analysis of HSV-1 and BHV-1 1 latency. 2003. Clinical Microbiology Reviews. 16:79-95


Lovato, L., M. Inman, G. Henderson, A. Doster., and C. Jones, C. 2003. Infection of cattle with a bovine herpesvirus 1 (BHV-1) strain that contains a mutation in the latency related gene leads to increased apoptosis in trigeminal ganglia during the transition from acute infection to latency. J of Virology, 77:4848-4857.


Geiser, V. and C. Jones. 2003. Stimulation of bovine herpesvirus 1 productive infection by the adenovirus E1A gene and the cellular transcription factor E2F4. J. of General Virology, 84:929-938.


Mott, K., N. Osorio, L. Jin, D. Brick, J. Naito, J. Cooper, G. Henderson, M. Inman, C. Jones, S. L. Wechsler, and G.-C. Perng. 2003. The BHV-1 LR genes ability to restore the high reactivation phenotype to an HSV-1 LAT null mutant appears to be due to its anti-apoptosis function. J. of General Virology, 84:2975-2985.


Devireddy, L., Y. Zhang, and C. Jones. 2003. Cloning and initial characterization of an alternatively spliced transcript encoded by the bovine herpes virus 1 latency related (LR) gene. J. of Neurovirology, 9: 612-622.


Henderson, G., G.-C. Perng, A. B. Nesburn, S. L. Wechsler, and C. Jones. 2004. The latency related (LR) gene encoded by bovine herpesvirus 1 (BHV-1) can suppress caspase 3 and caspase 9 cleavage during productive infection. J. of Neurovirology, 10:64-70.


Jiang, Y., M. Inman, Y. Zhang, N. A. Posadas , and C. Jones. 2004. A mutation in the latency related gene of bovine herpesvirus 1 (BHV-1) inhibits expression of proteins encoded by ORF2 and Reading Frame C during productive infection. J. of Virology 78:3184-3189.


Inman, M., J. Zhou, H. Webb, and C. Jones. 2004. Identification of a novel transcript containing a small open reading frame that is expressed during latency, and is antisense to the latency related gene of bovine herpes virus 1 (BHV-1). J. of Virology 5438-5447.


Fulton, R.W., Briggs, R.E., Payton, M.E., Confer, A.W., Saliki, J.T., Ridpath, J.F., Burge, L.J., Duff, G.C.: Maternally Derived Humoral Immunity to Bovine Viral Diarrhea Virus (BVDV)1a, BVDV1b, BVDV2, Bovine-Herpesvirus-1, Parainfluenza-3 Virus, Bovine Respiratory Syncytial Virus, Mannheimia haemolytica and Pasteurella multocida in Beef Calves, Antibody Decline by Half-life studies and Effect on Response to Vaccination. Vaccine, 22:644-650, 2004.


Berry, B.A., Krehbiel, C.R., Gill, D.R., Confer, A.W., Smith, R.A., Montelongo, M.: Effects of Dietary Energy and Starch Concentrations for Newly Received Feedlot Calves: I. Growth Performance and Health. J Anim Sci. 82:837-844, 2004.


Berry, B.A., Confer, A.W., Krehbiel, C.R., Gill, D.R., Smith, R.A., Montelongo, M.: Effects of Dietary Energy and Starch Concentrations for Newly Received Feedlot Calves: II. Acute-phase protein response. J Anim Sci. 82:845-850, 2004.


Dabo, S.M., Confer, A.W., Quijano-Blas, R.A.: Molecular and Immunological Characterization of Pasteurella multocida A:3 OmpA: Evidence of its Role in P. multocida Interaction with Extracellular Matrix Molecules. Microb Pathog. 35:147-157, 2003.


Cudd, L.A., Clarke, C.R., Clinkenbeard, K.D.: Mannheimia haemolytica Leukotoxin-Induced Increase in Leukotriene B4 Production by Bovine Neutrophils is Mediated by Sustained and Excessive Increase in Intracellular Calcium Concentration. FEMS Micro. Let. 224:85-90, 2003.


Cudd, L.A., Clarke, C.R., Clinkenbeard, K.D.: Contribution of Intracellular Calcium Stores to an Increase in Cytosolic Calcium Concentration Induced by Mannheimia haemolytica Leukotoxin. FEMS Micro. Let. 225:23-27, 2003.


Malazdrewich CP, Thumbikat MS, Abrahamsen MS, Maheswaran SK. Pharmacological inhibition of Mannheimia haemolytica lipopolysaccharide and leukotocin-induced inflammatory cytokine expression in bovine alveolar macrophages. Microbial Pathogenesis. 2004;36:159-169.


Malazdrewich CP, Thumbikat MS, Maheswaran SK. Protective effects of dexamathasone in experimental bovine pneumonic pasteurellosis. Microbial Pathogenesis. 2004;36:227-237.



ABSTRACTS:

L.J. Gershwin, L.B. Corbeil, L.J. Berghaus, K.F. Arnold, M.L. Anderson. IgE and Cytokine Profiles in Calves Concurrently Infected with BRSV and Histophilus somni. Presented at 7th International Veterinary Immunology Symposium, Quebec City, July 2004.


Chase CCL, G Elmowalid, LJ Braun and JF Ridpath. New paradigms for bovine viral diarrhea virus: understanding how BVDV interacts with the immune system. 36th annual conference of American Association of Bovine Practitioners, Columbus, OH, September 18-20, 2003, p. 189.


Hassan EAD, LJ Braun and CCL Chase. Interaction of bovine herpesvirus-1 glycoproteins with cellular cytoskeletal elements in bovine herpesvirus-1 infected cells. Abstract 130P. 84th annual meeting of Conference of Research Workers in Animal Disease, Chicago, IL, November 9-11, 2003.


Hassan EAD, LJ Braun and CCL Chase. Effect of protein kinase inhibitors on the replication of bovine herpesvirus-1 (BHV-1). Abstract 174. 84th annual meeting of Conference of Research Workers in Animal Disease, Chicago, IL, November 9-11, 2003.


Donovan DC, Reber AJ, Parks RJ, Collier C, Ely LO, and Hurley DJ. Extracellular pH alters the innate immune response by enhancing phagocytosis and decreases reactive oxygen species production. American Dairy Science Annual Meeting. St. Louis, MO. 2004; J Dairy Sci 87:179 (Suppl. 1).


Donovan DC, Collier C, Reber AJ, Parks RJ, and Hurley DJ. Extracellular pH alters immunity by decreasing the production of reactive oxygen and nitrogen species, but enhancing phagocytosis in bovine neutrophils and monocytes. International Conference of Production Diseases in Farm Animals. Michigan State University. July 18-22, 2004.
Abstract: A-14.


Donovan DC, Reber AJ, Parks RJ, and Hurley DJ. Acidic extracellular pH enhances phagocytosis and decreases reactive oxygen species production in polymorphonuclear neutrophils and monocytes. 2004; 7th International Veterinary Immunology Symposium. WK 13.6.10 p 415. Quebec City, Qc. July 25-29, 2004.


Reber, A.J., T. Okinaga, M. Tanner, A. Woolums, T. Leard, F. Milward, D.J. Hurley Evaluation of multiple immune parameters during development of immunity after vaccination with MLV or killed BVD. 7th International Veterinary Immunology Symposium. Program and Book of Abstracts, p. 150 (WK.1.6.7). Quebec City, Canada. July 25 - 30, 2004


Hurley, D.J., Pence, M., Lee, Y., Reber, A.J. and Parks, R.J. 2003. Characterization of an immunological defect observed in a herd of Hereford cattle. Proceedings of the Conference of Research Workers in Animal Diseases. 84:102


Reber, AJ, Okinaga, T, Tanner, M, Woolums, A, and Hurley, DJ. .2003. Comparison of cytokine production assays after stimulation of bovine mononuclear cells with Staphylococcal enterotoxin B or vaccine recall antigen. Proceedings of the Conference of Research Workers in Animal Diseases. 84:73P


Woolums AR, Mason G, Brown C, Williams S, Gould J, Fox J, Sturgeon S, Sanchez S, Bartlett P, Chitwood S. Microbiologic and histopathologic findings in cases of acute interstitial pneumonia (AIP) in feedyard cattle. Proceedings of the Conference for Research Workers in Animal Disease (CRWAD), Chicago IL, November 2003.


Harden, TT, Paulsen, DB, Godeny, EK, Olcott, BM, Smith, SL, Triche, PC, and OReilly, KL. Respiratory bovine coronavirus-induced pneumonia in newborn calves: a pilot study. South Central Branch of the American Society for Microbiology, New Orleans, LA, October 24-25, 2003.


OReilly, KL, Godeny, GK, Kousoulas, KG, Olcott, BM, Paulsen, DB, Harden, TT, Smith, S, and Triche, PC. Intrabronchial infection of newborn calves with respiratory bovine coronavirus. Animal Disease Research Workers of Southern States, Biloxi, MS, February 2004.


Johnson, TK, Triche, PC, and OReilly, KL. Immune response of newborn calves to intrabronchial infection with bovine coronavirus. Meeting of the Louisiana Biomedical Research Network, Baton Rouge, LA, July 28, 2004.


Nanduri, B., M. L. Lawrence, and S. C. Burgess. 2004. Determination of sub-MIC effects of antibiotics on Pasteurella multocida protein expression using cleavable isotope coded affinity tag reagents. 104th General Meeting of the American Society for Microbiology, New Orleans, Louisiana.



DISSERTATIONS:

Kalina, WV. The influence of Alternaria alternate Aerosol on the Development of Immune Responses in Calves During a Primary and Secondary Bovine Respiratory Syncytial Virus Infection. University of California, Davis, 2004.


Hassan, Ehab. Investigation of the role of viral glycoproteins gE AND gI in bovine herpesvirus type 1 (BHV-1) pathogenesis: study of cytoskeleton and phosphorylation. PhD Dissertation, South Dakota State University, 2004.


Fogarty-Fairbanks, Kristine. New clinical applications for three USDA licensed vaccines in the prevention of infectious bovine rhinotracheitis or bovine viral diarrhea virus. Master of Science Thesis, South Dakota State University, 2004.


Anthony Vandenbush. 2003. Interactions between Mycoplasma bovis and bovine lymphocytes: characterization of a lympho-inhibitory peptide produced by Mycoplasma bovis. PhD Thesis, Iowa State University.

11/07/2005

PEER-REVIEWED PUBLICATIONS:

Rosenbusch, R. F., Kinyon, J. M., Apley, M., Funk, N. D., Smith, S., and L. J. Hoffman. In vitro antimicrobial inhibition profiles of Mycoplasma bovis isolates recovered from various regions of the United States from 2002-2003. (In Press, J. Vet Diagn. Invest.).


Lu, X., and R. F. Rosenbusch. 2004. Endothelial cells from bovine pulmonary microvasculature respond to Mycoplasma bovis preferentially with signals for mononuclear cell transmigration. Molecular Pathogenesis 37: 253-261.


Nanduri, B., M. L. Lawrence, and S. C. Burgess. In press. Proteomic analysis using an unfinished bacterial genome: the effects of sub-minimum inhibitory concentrations of antibiotics on Mannheimia haemolytica virulence factor expression. Proteomics.


Reeks, B. Y., F. R. Champlin, D. B. Paulsen, D. W. Scruggs, and M. L. Lawrence. 2005. Effects of sub-MIC antibiotic levels and temperature on growth kinetics and outer membrane protein expression in Mannheimia haemolytica and Haemophilus somnus. Can. J. Vet. Res. 69:1-10.


Boyd, B. L., Lee, T. M., Kruger, E. F., Pinchuk, L. M . 2004. Cytopathic and Noncytopathic Bovine Viral Diarrhoea Virus Biotypes affect Fluid Phase Uptake and Mannose Receptor-Mediated Endocytosis in Bovine Monocytes. Vet. Immunol. Immunopathol. 102:53-65.


S.-R. Lee, G. T. Pharr, A. M. Cooksey, F. M. McCarthy, B. L. Boyd, and L. M. Pinchuk. Differential detergent fractionation for non-electrophoretic bovine blood monocyte proteomics reveals proteins involved in professional antigen presentation. In preparation.


Klink H.A, R.P. Brady, C. L.Topliff, K.M. Eskridge, S. Srikumaran, C. L. Kelling. 2005. Influence of bovine respiratory syncytial virus F glycoprotein N-linked glycans on in vitro expression and on antibody responses in BALB/c mice. Vaccine. Accepted for publication.


Kelling, C. L., B.D. Hunsaker, D.J. Steffen, 2005. Characterization of protection in experimentally-infected calves from systemic infection or disease by vaccination with modified-live noncytopathic bovine viral diarrhea virus type 1. American Journal of Veterinary Research. Accepted for publication.


Topliff CL, Chon SK, Donis RO, Eskridge KM, Kelling CL. 2005. In vitro and in vivo translational efficiencies of 5' untranslated region from eight genotype 2 bovine viral diarrhea virus isolates. Virology 331: 349-356.


Achenbach JE, Topliff CL, Vassilev VB, Donis RO, Eskridge KM, Kelling CL. 2004. Detection and quantitation of bovine respiratory syncytial virus using real-time quantitative RT-PCR and quantitative competitive RT-PCR assays. Journal of Virological Methods 121: 1-6.


Brady RP, Topliff CL, Kelling CL. 2004. In vitro expression of full-length and truncated bovine respiratory syncytial virus G proteins and their antibody responses in BALB/c mice. Vaccine 22: 3762-3768.


Henderson, G., G.-C. Perng, A. B. Nesburn, S. L. Wechsler, and C. Jones. 2004. The latency related (LR) gene encoded by bovine herpesvirus 1 (BHV-1) can suppress caspase 3 and caspase 9 cleavage during productive infection. J. of Neurovirology. 10:64-70.


Jiang, Y., M. Inman, Y. Zhang, N. A. Posadas , and C. Jones. 2004. A mutation in the latency related gene of bovine herpesvirus 1 (BHV-1) inhibits expression of proteins encoded by ORF2 and Reading Frame C during productive infection. J. of Virology 78:3184-3189.


Inman, M., J. Zhou, H. Webb, and C. Jones. 2004. Identification of a novel transcript containing a small open reading frame that is expressed during latency, and is antisense to the latency related gene of bovine herpes virus 1 (BHV-1). J. of Virology 78:5438-5447.


Henderson, G., Y. Zhang, M. Inman, D. Jones and C. Jones. 2004. Infected cell protein 0 encoded by bovine herpesvirus 1 can activate caspase 3 when overexpressed in transfected cells. J Gen Virol ; 85: 3511-3516


Perez, S., M. Inman, A. Doster, and C. Jones. 2005. The latency related gene encoded by bovine herpesvirus 1 (BHV-1) promotes virus growth and reactivation from latency in tonsils of infected calves. J. of Clinical Microbiology. 43: 393-401.


Zhang, Y. and C. Jones. 2005. Identification of functional domains within the bICP0 protein encoded by BHV-1. J. of General Virology, 86:879-886.


Geiser, V., Y. Zhang, & C. Jones. 2005. Analysis of a bovine herpesvirus 1 (BHV-1) recombinant virus that does not express the bICP0 protein. J. of General Virology. 86: 1987-1996.


Confer, A.W., Fulton, R.W., Step, D.L., Johnson, B.J., Ridpath, J.F.: Viral Antigen Distribution in the Respiratory Tract of Cattle Persistently Infected with Bovine Viral Diarrhea Virus Subtype 2a. Veterinary Pathology, 42:192-199, 2005.


Step, D.L, Confer, A.W., Kirkpatrick, J.G., Richards, J.B., Fulton, R.W.: Respiratory Tract Infections in Dairy Calves from Birth to Breeding Age: Detection by Laboratory Isolations and Seroconversions. Bovine Practitioner, 39:44-532, 2005.


Fulton, R.W., Briggs, R.E., Ridpath, J.F., Saliki, J.T., Confer, A.W., Payton, M.E., Duff, GC, Step, D.L., Walker, D.: Transmission of Bovine Viral Diarrhea Virus 1b to Susceptible and Vaccinated Calves by Exposure to Persistently Infected Calves. Canadian Journal for Veterinary Research, 69:161-169, 2005.


Welsh RD, Dye LB, Payton ME, Confer AW. Frequency of isolation and antimicrobial susceptibilities of bacterial pathogens from bovine pneumonia: 1994-2002. J Vet Diag Invest 16:426-431, 2004.


Ayalew S, Confer AW, Blackwood ER. Characterization of Immunodominant and Potentially Protective Epitopes of Mannheimia haemolytica Serotype 1 Outer Membrane Lipoprotein PIpE. Infect and Immun 72:7265-7274, 2004.


Prado ME, Dabo SM, Confer AW. Immunogenicity of iron-regulated outer membrane proteins of Pasteurella multocida A:3 in cattle: molecular characterization of the immunodominant heme acquisition system receptor (HasR) protein. Vet Microbiol, 105:269-280, 2005.


Carter JN, Gill DR, Lalman DL, Krehbiel CR, Confer AW, Smith RA, Claypool PL, McDowell LR. Vitamin E supplementation in the diet of newly arrived feedlot cattle. J Anim Sci 83:1924-1932, 2005.


Thumbikat, P., T. Dileepan, M.S. Kannan and S.K. Maheswaran. 2005. Mechanisms underlying Mannheimia haemolytica leukotoxin-induced oncosis and apoptosis of bovine leukocytes. Microbial Pathogenesis 38: 161-172.


Dileepan, T., P. Thumbikat, B. Walcheck, M.S. Kannan, and S.K. Maheswaran. 2005. Recombinant expression of bovine LFA-1 and characterization of its role as the receptor for Mannheimia haemolytica leukotoxin. Microbial Pathogenesis 38: 249-257.


Thumbikat, P., T. Dileepan, M.S. Kannan and S.K. Maheswaran. 2005. Characterization of Mannheimia (Pasteurella) haemolytica leukotoxin interaction with bovine alveolar macrophage b2 integrins. Veterinary Research. September Issue.


Dileepan, T., M.S. Kannan, B. Walcheck, P. Thumbikat, and S.K. Maheswaran. 2005. Mapping of the binding site for Mannheimia haemolytica leukotoxin within the bovine CD18. Infection and Immunity. 73: 5233-5237.


Fairbanks KK, CL Rinehart, WC Ohnesorge, MM Loughin and CCL Chase. 2004. Evaluation of fetal protection against experimental infection with type 1 and type 2 bovine viral diarrhea virus after vaccination of the dam with a bivalent modified-live virus vaccine. JAVMA 225:1898-2004


Al-Mubarak, A. and Chowdhury, S.I.. Glycoprotein I (gI)-deleted BHV-5 retains significant neurovirulence. 2004. J. Neurovirology 10:233-243.


Hollis LC, Smith JF, Johnson BJ, Kapil S, Mosier DA: A Comparison of Serological Responses when Modified-live Infectious Bovine Rhinotracheitis Virus Vaccine, Mannheimia haemolytica Bacterin-Toxoid are Administered with Needle-free versus Conventional Needle-based Injection in Yearling Feedlot Steers. 2005. The Bovine Practitioner 39:106-109.


Hollis LC, Smith JF, Johnson BJ, Kapil S, Mosier DA: A Comparison of Serological Responses when Modified-live Infectious Bovine Rhinotracheitis Virus Vaccine, Mannheimia haemolytica Bacterin-Toxoid and Leptospira pomona Bacterin are Administered with Needle-free versus Conventional Needle-based Injection in Holstein Dairy Calves. 2005. The Bovine Practitioner. 39:110-114.


Dunn J, Kaneene JB, Grooms D, Bolin S, Bolin C, Bruning-Fann C. Effects of positive results for Mycobacterium avium subsp paratuberculosis as determined by microbial culture of feces or antibody ELISA on results of caudal fold tuberculin test and interferon-gamma assay for tuberculosis in cattle. American Journal of Veterinary Research, 2005;226:429-435


Tahir ZM, Alocilja EC, Grooms DL. Polyaniline synthesis and its biosensor application. Biosens Bioelectron. 2005;15;20(8):1690-1695.


Boudreaux, C.M., Corstvet, R.E., Cooper, R.K., and Enright, F.M., 2005. Effects of cecropin B transgene expression on Mannheimia haemolytica serotype 1 colonization of the nasal mucosa of calves. A J Vet Res. In Press.


Chad M Petit; Jeffery M Melancon ; Vladimir N Chouljenko; Robert C Colgrove; Michael Farzan; David M Knipe; Konstantin Kousoulas. 2005. Genetic Analysis of the SARS-Coronavirus Spike Glycoprotein Functional Domains Involved in Cell-Surface Expression and Cell-to-Cell Fusion (Virology; In press).



Doyle, C.K., Labruna, M.B., Breitschwerdt, E.B., Tang, Y, Corstvet, R.E., Hergarty, B.C., Bloch, K.C., Li, P., Walker, D.H., and McBride, J.W., 2005. Detection of medically important Ehrlichia by quantitative multicolor TaqMan real-time polymerase chain reaction of the dsb gene. J Mol Diagn 7(4):1-7.


Vladimir N Chouljenko, Chad M. Petit and K. G. Kousoulas. Delineation of functional domains of the spike glycoprotein encoded by enteric and respiratory strains of bovine coronavirus (In preparation).


Woolums AR, Loneragan GH, Hawkins LL, Williams SM. Baseline management practices and animal health data reported by U.S. feedlots responding to a survey regarding acute interstitial pneumonia. Bov Pract, 39:116-124; 2005.


Woolums AR, Loneragan GH, Hawkins LL, Williams SM. A survey of the relationshiop between management practices and risk of acute interstitial pneumonia at U.S. feedlots. Bov Pract; 39:125-133; 2005.


Reber, AJ, Hippen, AR, Hurley, DJ, 2005. Ingestion of whole colostrum rapidly induces the capacity in newborn calves to stimulate and respond in one-way mixed leukocyte cultures. AJVR (in Press).


Briggs, R. E., Tatum, F. M. Generation and molecular characterization of new temperature-sensitive plasmids intended for genetic engineering of the Pasteurellaceae. Appl. Environ. Microbiol. Accepted July 19, 2005.



Briggs, R. E., Tatum, F. M. Construction of Pasteurella haemolytica vaccines. U.S. Patent 6,793,927 issued September 21, 2004.


Fulton, R. W., Briggs, R. E., Ridpath, J. F., Saliki, J. T., Confer, A. W., Payton, M. E., Duff, G. C., Step, D. L, Walker, D. Transmission of bovine viral diarrhea virus 1b to susceptible and vaccinated calves by exposure to persistently infected calves. Can J Vet Res. 2005; 69:161-169.


Meyerholz DK, Grubor B, Gallup JM, Lehmkuhl HD, Anderson RD, Lazic T, Ackermann MR. Adenovirus-mediated gene therapy enhances parainfluenza virus 3 infection in neonatal lambs. J Clin Microbiol. 2004 Oct;42(10):4780-7.


Meyerholz DK, Grubor B, Fach SJ, Sacco RE, Lehmkuhl HD, Gallup JM, Ackermann MR. Reduced clearance of respiratory syncytial virus infection in a preterm lamb model. Microbes Infect. 2004 Nov;6(14):1312-9.


Tatum, F. M., Yersin, Y. G., Briggs, R. E. Construction and virulence of a Pasteurella multocida FhaB2 mutant in turkeys. Microb Pathog. 2005 Jul-Aug;39(1-2):9-17.


Tatum, F. M., Briggs, R. E. Construction of in-frame aroA deletion mutants of Mannheimia haemolytica, Pasteurella multocida, and Haemophilus somnus using a new temperature-sensitive plasmid. Appl. Environ. Microbiol. Accepted July 19, 2005.


Atapattu, D. and C.J. Czuprynski. 2005. Mannheimia haemolytica leukotoxin induces apoptosis of bovine lymphoblastoid cells (BL-3) via a caspase-9 dependent mitochondrial pathway. Infect. Immun. (in press).


Kuckleburg, C., M.J. Sylte, T. J. Inzana, L.B. Corbeil, B. Darien and C.J. Czuprynski. 2005. Bovine platelets activated by Haemophilus somnus or its lipooligosaccharide cause endothelial cell damage in vitro. Microb Pathogen. 38:23-32.


Lago, A., S.M. McGuirk, T.B. Bennett,, N.B. Cook,, and K. V. Nordlund. Submitted. Calf respiratory disease and pen microenvironments in naturally ventilated calf barns in winter. J. Dairy Sci.


Leite, F., D. Atapattu, C. Kuckleburg, , R. Schultz, and C.J. CZUPRYNSKI. 2004. Incubation of bovine PMNs with conditioned medium from BHV-1 infected peripheral blood mononuclear cells increases their susceptibility to Mannheimia haemolytica leukotoxin. Vet. Immunol. Immunopathol. 103:187-193.


Qiu, Z., J. S. Harms, J. Zhu, and G. A. Splitter. 2004. Bovine herpesvirus tegument protein VP22 enhances thymidine kinase/Ganciclovir suicide gene therapy for neuroblastomas compared to herpes simplex virus VP22. J. Virol. 78:4224-4233.


Qiu Z, Zhu J, Harms JS, Friedrichsen J, Splitter GA. 2005. Bovine herpesvirus VP22 induces apoptosis in neuroblastoma cells by upregulating the expression ratio of Bax to Bcl-2. Hum Gene Ther. 16:101-108.


Slack, J., Thomas, C and Peek, S.F. 2004. Pneumothorax in dairy cattle : 30 cases (1990-2003). J. Amer. Vet. Med. Assoc. 225:732-735.


Sylte, M.J., C. J. Kuckleburg, L. B. Corbeil, T. J. Inzana, P. J. Bertics, and C. J. Czuprynski. 2005. Stimulation of P2X7 enhances Haemophilus somnus lipooligosaccharide-mediated apoptosis of endothelial cells. J. Leuk. Biol. 77:958-965.


Sylte, M.J. C. J. Kuckleburg, F.P. Leite, T.J. Inzana and C.J. CZUPRYNSKI. 2005. Interleukin-1 beta diminishes Haemophilus somnus lipooligosaccharide-mediated apoptosis of endothelial cells. Microb. Pathogen. (in press).


Sylte, M., T. Inzana and C. J. CZUPRYNSKI. Submitted. Role of tumor necrosis factor in endothelial cell apoptosis caused by Haemophilus somnus lipooligosaccharide. Vet. Immunol. Immunopathol.


Zhu J, Z. Qiu, C. Wiese, Y. Ishii, J. Friedrichsen, G. Rajashekara, and G.A. Splitter. 2005. Nuclear and mitochondrial localization signals overlap within bovine herpesvirus 1 tegument protein VP22. J. Biol. Chem. 280:16038-16044.



ABSTRACTS:


Nanduri, B., S. C. Burgess, and M. L. Lawrence. 2005. Sub-MIC concentrations of antibiotics decrease Mannheimia haemolytica leukotoxin expression. 105th General Meeting of the American Society for Microbiology, Atlanta, Georgia.


Nanduri, B., M. L. Lawrence, and S. C. Burgess. 2005. Proteomic profiling of M. haemolytica; a bacterial pathogen with a draft genome. 53rd ASMS Conference on Mass Spectrometry, San Antonio, Texas.


Lawrence, M. L. 2005. Impact of sub-MIC levels of chlortetracycline and chlortetracycline/ sulfamethazine on growth kinetics of Mannheimia haemolytica and Haemophilus somnus. Summer 2005 Academy Of Veterinary Consultants Conference, Kansas City, Missouri.


Hunsaker, B.D., D.J. Steffen, CL. Topliff, C.L. Kelling, 2004. Characterization of protection in calves from systemic infection or disease by vaccination with modified-live noncytopathic bovine viral diarrhea virus type 1. Conference of Research Workers in Animal Disease.


Klink,HA, R.P. Brady, C.L.Topliff, K.M.Eskridge, S. Srikumaran, C.L.Kelling. 2004. Influence of bovine respiratory syncytial virus F glycoprotein N-linked glycans on in vitro expression and on antibody responses in BALB/c mice. Conference of Research Workers in Animal Disease.


Topliff, C.L., S.K.Chon, R.O. Donis, K.M. Eskridge, C.L Kelling. 2004. Translational efficiencies of the 5' untranslated region from eight genotype 2 bovine viral diarrhea virus field isolates varying in virulence. Conference of Research Workers in Animal Disease.



Fulton, R.W., Burge, L.J., dOffay, J.M., Funk, R., Weaver, G.D., Van Campen, H., Johnson, B.J.: Immune Response Differences in Serums from Bovine Herpesvirus-1 Vaccinated Cattle: Depenndence of Viral Strarin. 47th Annual Meeting of AAVLD. October 22-24, 2004. Greensboro, NC.


Fulton, R.W., Ridpath, J.F., Ores, S., Saliki, J.T., Burge, L.J., Confer, A.W.: Bovine Viral Diarrhea Virus (BVDV) Subtypes in Diagnostic Laboratory Accessions from Clinical and Necropsy Cases: Distribution of BVDV1a, BVDV1b, and BVDV2a Subtypes. 47th Annual Meeting of AAVLD. October 22-24, 2004. Greensboro, NC.


Confer, A.W., Fulton, R.W., Step, D.L., Johnson, B.J., Ridpath, J.F.: Viral Antigen Distribution in the Respiratory Tract of Cattle Persistently Infected with Bovine Viral Diarrhea Virus Subtype 2a. 47th Annual Meeting of AAVLD. October 22-24, 2004. Greensboro, NC.


Dabo SM, Anderson BE, Confer AW, Gupta S. Expression, Purification and Binding Activity of B. henselae Pap 31. Proceedings 105th Annual Meeting of American Society of Microbiology, Atlanta, GA. 2005


Ayalew S, Blackwood ER, Confer AW. Sequence diversity of the immunogenic outer membrane lipoprotein PIpE from Mannheimia haemolytica serotypes 1,2 and 6. Proceedings 105th Annual Meeting of American Society of Microbiology, Atlanta, GA 2005.


Chase CCL, DM Miskimins, T Graham, L Braun, P Steen and J Ridpath. Evidence of bovine viral diarrhea virus persistent infection in two white-tail deer in southeastern South Dakota. Proceedings of the 37th annual conference of American Association of Bovine Practitioners, Fort Worth, TX, September 23-25, 2004, p. 169.


Fogarty-Fairbanks K, CL Rinehart, WC Ohnesorge, MM Loughin and CCL Chase. Fetal protection against BVDV type 1 or 2 heterologous challenge. Proceedings of the 37th annual conference of American Association of Bovine Practitioners, Fort Worth, TX, September 23-25, 2004, p.171.


Fogarty-Fairbanks K, J Campbell and CCL Chase. Subcutaneous dose of infectious bovine rhinotracheitis virus provides early protection against an intranasal challenge. Proceedings of the 37th annual conference of American Association of Bovine Practitioners, Fort Worth, TX, September 23-25, 2004, p. 289.


Tigabu B, CCL Chase, LJ Braun. BVDV influences the expression of Toll-like receptors. Abstract W13-4. 24th Annual Meeting of American Society for Virology, University Park, PA June 18-22, 2005.


Donovan, DC, Barton, MH, Norton, N, Ely, LO, Hurley, DJ. Modulation of innate immunity by in vitro treatment of keukocytes with CD14, lactoferrin and IgG, (Abstract) pg 39 Proceedings of the 84th CRWAD meeting, Chicago, IL November 14-16, 2004


Okinaga, T, Hurley, DJ, Woolums, AR, Miao, C, Zarlinga, DS. Comparison of bovine cytokine gene experession as measured by competitive and real-time PCR. (Abstract) pg 41 Proceedings of the 84th CRWAD meeting, Chicago, IL November 14-16, 2004


Okinaga, T, Hines II, ME, Hurley, DJ. Real-time PCR measurements of cytokine mRNA from cattle and goats. ( Abstract) pg 40 Proceedings of the 84th CRWAD meeting, Chicago, IL November 14-16, 2004


Reber, AJ, Okinaga, T, Tanner, M, Woolums, AR, Hurley, DJ. Development of immunity after vaccination with MLV or killed BVD vaccines. ( Abstract) pg 40 Proceedings of the 84th CRWAD meeting, Chicago, IL November 14-16, 2004


M. Wiggins, A. Woolums, D. J. Hurley, D. Cole, S. Sanchez. The prevalence of Mycoplasma bovis in a subpopulation of Georgia cattle, (Abstract) Proceedings of the 84th CRWAD meeting, Chicago, IL November 14-16, 2004


BOOK CHAPTER

Vaccines, July 2005. Blackwell Publishing, Ames, IA.: Bovine Viral Diarrhea Virus: Diagnosis, Management and Control. Editors, Dr. S. Goyal and Dr. J. F. Ripdath. Pp. 209-222.

03/14/2007

PEER REVIEWED PUBLICATIONS (2001)


Brock KV, Cortese VS. 2001. Experimental fetal challenge using type II bovine diarrhea virus in cattle vaccinated with a modified-live virus vaccine. Vet therapeutics. 2:354-360.


Butler JA, Pinnow CC, Thomson JU, Levisohn S, Rosenbusch RF. 2001. Use of arbitrarily primed polymerase chain reaction to investigate Mycoplasma bovis outbreaks. Vet. Microbiol. 78: 175-181.


Chouljenko VN, Lin XQ, Storz J, Kousoulas KG. 2001. Elucidation of the genomic nucleotide sequence of bovine coronavirus and analysis of cryptic leader mRNA fusion sites. Adv. Exp. Med. Biol. 2002. 494: 49-55.


Chouljenko VN, Lin XQ, Storz J, Kousoulas KG, Gorbalenya AE. 2001. Comparsion of genomic and predicted amino acid sequences of respiratory and enteric bovine coronaviruses isolated from the same animal with fatal shipping pneumonia. J. Gen. Virol. 82: 2927-2933.


Confer AW, Suckow MA, Montelongo M, Dabo SM, Miloscio LJ, Gillespie AJ, Meredith GL. 2001. Intranasal vaccination of rabbits with Pasteurella multocida A:3 outer membranes expressing iron-regulated proteins. Amer. J. Vet. Res. 62: 697-703.


Confer AW, Montelongo M, Brown MJ, Fergen BJ, Clement JC. 2001. Onset of Serum Antibodies to Pasteurella (Mannheimia) haemolytica following vaccination with five commercial vaccines. Bov. Practitioner. 35: 141-148.


DeBey BM, Lehmkuhl HD, Chard Bergstrom C, Hobbs LA. 2001. Ovine adenovirus serotype 7 associated mortality in lambs in the US. Vet. Pathol. 38: 644 648.




Frazier M, Pence M, Mauel MJ, Ligget A, Hines ME, Sangster L, Lehmkuhl HD, Miller D, Styer E, West J, Baldwin CA. 2001. Endometritis in postparturient cattle associated with bovine herpesvirus 4 infection: 15 cases. J. Diagnos. Invest. 13: 502 508.


Givens MD, Galik PK, Riddell KP, Stringfellow DA, Brock KV, Bishop MD, Eilertsen KJ, Loskutoff NM. 2001. Validation of a reverse transcription nested polymerase chain reaction (RTnPCR) to detect bovine virus diarrhea virus (BVDV) associated with in vitro-derived bovine embryos and co-cultured cells. Theriogenology. 56: 787-799.


Grooms DL, Kaiser L, Walz PH, Baker JC. 2001. Study of cattle persistently infected with bovine viral diarrhea virus that lack detectable virus in their serum. J. Am. Vet. Med. Assoc. 219: 629-631.


Hart ML, Mosier DA, Chapes SK. 2001. The response of Tlr-4-receptor positive cells to infection. 35th Annu. Soc. for Leuk. Biol., Honolulu, HI, J. Leukocyte Biol. supp. 67.


Inman M, Zhange Y, Geiser V, Jones C. 2001. The zinc ring finger of bovine herpes virus 1 encoded bICP0 is necessary for transcriptional regulation and infection. J. Gen. Virol. 82: 483-492.


Inman M, Lovato L, Doster A, Jones C. 2001. A mutation in the latency related gene of bovine herpesvirus 1 leads to impaired ocular shedding in acutely infected calves. J. Virol. 75: 8507-8515.


Jeyaseelan, S, Kannan MS, Briggs RE, Thumbikat P, Maheswaran SK. 2001. Mannheimia haemolytica leukotoxin activates a non-receptor tyrosine kinase-signaling cascade in bovine leukocytes which induces biological activity. Infect. Immun. 69: 6131-6139.


Jeyaseelan S, Kannan MS, Hsuan SL, Singh AK, Walseth TF, Maheswaran SK. 2001. Pasterella haemolytica leukotoxin  induced cytolysis of bovine leukocytes: Role of arachidonic acid and its regulation. Microb. Pathog. 30: 59-69.


Kalfa VC, Jia HP, Kunkle RA, McCray Jr. PB, Tack BF, Brogden KA. 2001. Congeners of SMAP29 kill ovine pathogens and induce ultrastructural damage in bacterial cells. Antimicrob. Agents Chemother. 45: 3256-3261.


Lafleur RL, Malazdrewich C, Jeyaseelan S, Bleifield E, Abrahamsen MS, Maheswaran SK. 2001. Lipopolysaccharide enhances cytotolysis and inflammatory cytokine induction in bovine alveolar macrophages exposed to Pasteurella (Mannheimia) haemolytica leukotoxin. Microb. Pathog. 30: 347-357.


Leite F, Sylte M, OBrien S, Schultz R, Peek S, Van Reeth K, Czuprynski C. 2001. Effect of experimental infection of cattle with bovine herpesvirus-1 on the ex vivo interaction of bovine leukocytes with Mannheimia haemolytica leukotoxin. Vet. Immunol. Immunopathol. 84: 97-110.


Malazdrewich C, Ames TR, Abrahamsen MS, Maheswaran SK. 2001. Pulmonary expression of tumor necrosis factor  alpha, interleukin  beta, and interleukin  8 in the acute phase of bovine pneumonic pasteurellosis. Vet. Pathol. 38: 297-310.


Ramirez-Romero R, Brogden KA, Gallup JM, Sonea IM, Ackermann, MR. 2001. Mast cell density and substance P-like immunoreactivity during the initiation and progression of lung lesions in ovine Mannheimia (Pasteurella) haemolytica pneumonia. Microb. Pathogen. 30: 325-335.


Walz PH, Bell TH, Wells J, Grooms DL, Kaiser L, Maes RK, Baker JC. 2001. Relationship between level of viremia and disease manifestations in calves experimentally infected with bovine viral diarrhea virus. Am. J. Vet. Res. 62: 1095-1103.


Walz PH, Bell TH, Wells J, Grooms DL, Kaiser L, Maes RK, Baker JC. 2001. Platelet aggregation responses and virus isolation from platelets in calves experimentally infected with type I or type II bovine viral diarrhea virus. Can. J. Vet. Res. 65:241-247.


Wang P, Hurley DJ, Braun LJ, Chase CCL. 2001. Detection of bovine herpesvirus 1 in peripheral blood mononuclear cells 8 months post infection. J. Vet. Diag. Invest. 13: 424-427.


Wittum TE, Groteueschen DM, Brock KV, Kvasnicka WG, Floyd JG, Kelling CL, Odde KG. 2001. Persistent bovine viral diarrhea virus infection in U.S. beef herds. Vet. Prev. Med. 49: 83-94.


Zhang Y, Jones C. 2001. The bovine herpes virus 1 immediate early protein (bICP0) is associated with histone deaetylase 1 to activate transcription. J. Virology. 75: 9571-9578.



PEER REVIEWED PUBLICATIONS (2002)


Akula S, Hurley DJ, Wixon RL, Wang C, Chase CCL. 2002. Effect of genistein on replication of bovine herpesvirus type 1. Am. J. Vet. Res. 63:1124-1128.


Ambagala AP, Feng Z, Barletta RG, Srikumaran S. 2002. Molecular cloning, sequencing, and characterization of bovine transporter associated with antigen processing 2 (BoTAP2). Immunogenetics. 54:30-38.


Carter JN, Meredith GL, Montelongo M, Gill DR, Krehbiel CR, Payton ME, Confer AW. 2002. Relationship of vitamin E supplementation and antimicrobial treatment with acute-phase protein responses in cattle affected by naturally acquired respiratory tract disease. Am. J. Vet. Res. 63: 1111-1117.


Champlin FR, Shryock TR, Patterson CE, Austin FW, Ryals PE. 2002. Prevalence of a novel capsule-associated lipoprotein among Pasteurellaceae pathogenic in animals. Curr. Microbiol. 44: 297-301.


Chowdhury SI, Onderci M, Bhattacharjee PS, Al-Mubarak A, Weiss ML, Zhou Y. 2002. Bovine herpesvirus 5 (BHV-5) Us9 is essential for BHV-5 neuropathogenesis. J. Virol. 76: 3839-3851.


Deshpande M, Ambagala TC, Ambagala APN, Srikumaran S. 2002. Bovine CD18 is necessary and sufficient to mediate Mannheimia (Pasteurella) haemolytica leukotoxin induced cytolysis. Infection and Immunity. 70: 5058 5064.


Evermann JF, Ridpath JF. 2002. Clinical and epidemiologic observations of bovine viral diarrhea virus in the northwestern United States. Vet Microbiol. 89(2-3): 129-39.


Fales-Williams AJ, Gallup JM, Ramirez-Romero R, Brogden K, Ackermann MR. 2002. Increased anionic peptide distribution and intensity during progression and resolution of bacterial pneumonia. Clin. Diagn. Lab. Immunol. 1:28-32.


Fent GM, Fulton RW, Saliki JT, Caseltine SL, Lehmkuhl HD, Confer AW, Purdy CW, Briggs RE, Loan RW, Duff GC. 2002. Bovine adenovirus-7 infections in postweaning calves. Am. J. Vet. Res. 63: 976-978.


Flores EF, Risatti GR, et al. 2002. Expression of the mouse Fc receptor B2 in bovine cells rescues the infectivity of conditionally neutralized bovine viral diarrhea virus. Vet. Microbiol. 85: 99-109.


Frank GH, Briggs RE, Duff GC, Loan RW, Purdy CW. 2002. Effects of pretransit vaccination and arrival medication with florfenicol on the health of transported calves and the presence of Mannheimia haemolytica organisms in nasal secretions. Am. J. Vet. Res. 63: 251 256.


Fulton RW, Cook BJ, Step DL, Confer AW, Saliki JT, Burge LJ, Welsh RD, Blood KS, Payton MD. 2002. Evaluation of animal health status of calves and their impact on feedot performance: Assessment of a retained ownership program of postweaning calves. Can. J. Vet. Res. 66:173-180.


Fulton RW, Ridpath JF, Saliki JT, Briggs RE, Confer AW, Burge LT, Purdy CW, Loan RW, Duff GC, Payton ME. 2002. Bovine viral diarrhea virus (BVDV)1b: Predominant subtype in calves with respiratory disease. Can. J. Vet. Res. 66: 181-190.


Gatto NT, Dabo SM, Hancock RE, Confer AW. 2002. Characterization of, and immune responses of mice to, the purified OmpA-equivalent outer membrane protein of Pasteurella multocida serotype A:3 (Omp28). Vet Microbiol. 87: 221-235.


Geiser G, Inman M, Zhang Y, Jones C. 2002. The latency related (LR) gene of bovine herpes virus 1 (BHV 1) can inhibit the ability of bICP0 to activate productive infection. J. of General Virology. 83: 2965 2971.


Gopinath RS, Ambagala APN, Hinkley S, Srikumaran S. 2002. Effects of virion host shut off activity of bovine herpesvirus 1 on MHC class I expression. Viral Immunology. 15: 595 608.


Grooms DL, Coe PH. Antibody response following vaccination for respiratory viruses in preconditioned calves. Vet. Therap. 3: 119-127


Grooms DL, Keilan E. 2002. Screening of neonatal calves for bovine viral diarrhea virus by immunohistochemistry on skin samples. Clin. Diagn. Lab. Immun. 9: 898-900.


Guey-Chuen P, Maguen B, Jing L, Mott KR, Osorio N, Slanina SM, Yukht A, Ghiasi H, Nesburn AB, Inman M, Henderson G, Jones C, Wechsler SL. 2002. A gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 LAT gene and restore wild type reactivation levels. J. Virol. 76: 1224-1235.


Harding MJ, Cao X, Shams H, Johnson AF, Vassilev VB, Wheeler DW, Haines D, Sibert GJ, Nelson LD, Campos M, Donis RO. 2002. Role of bovine viral diarrhea virus biotype in the establishment of fetal infections. Am. J. Vet. Res. 63(10): 1455 63.


Inman M, Lovato L, Doster A, Jones C. 2002. A mutation in the latency related gene of bovine herpesvirus 1 disrupts the latency reactivation cycle in calves. J. of Virology. 76: 6771 6779.


Jeyaseelan, S, Srinand S, Maheswaran SK. 2002. Role of Mannheimia haemolytica leukotoxin in the pathogenesis of bovine pneumonic pasteurellosis. Animal Health Research Reviews. 3: 69-82.


Kelling CL, Steffen DJ, Topliff CL, Eskridge KM, Donis RO, Higuchi DS. 2002. Comparative virulence of bovine viral diarrhea virus type II in experimentally inoculated six to nine month old calves. Am. J. of Vet. Res. 63: 1379 1384.


Kelling CL, Steffen DJ, Cooper VL, Higuchi DS, Eskridge KM. 2002. Effect of acute bovine viral diarrhea virus alone, bovine rotavirus alone, or concurrent infection with both on enteric disease in gnotobiotic neonatal calves. Am. J. of Vet. Res. 63: 1179 1186.


Leite F, OBrien S, Sylte MJ, Page T, Atapattu D, Czuprynski CJ. 2002. Inflammatory cytokines enhance the interaction of Mannheimia haemolytica leukotoxin with bovine peripheral blood neutrophils in vitro. Infect. Immun. 70:4336-4343.


Maheswaran SK, Thumbikat P, Dileepan T. 2002. Current knowledge on pathogenesis of lung injury caused by Mannheimia haemolytica and Pasteurella multocida in the bovine. In: Recent Developments and Perspectives in Bovine Medicine. p. 160-167.


Pillars RA, Grooms DL. 2002. Serological evaluation of five unvaccinated heifers for detecting herds persistently infected with bovine viral diarrhea virus. Am. J. Vet. Res. 63: 499-5.


Purdy CW, Straus DC, Chirase N, Parker DB, Ayers JR, Hoover MD. 2002. Effects of aerosolized endotoxin in feedyard dust on weanling goats. Small Rum. Res. 446: 133.


Vanden Bush TJ, Rosenbusch RF. 2002. Mycoplasma bovis induces apoptosis of bovine lymphocytes. FEMS Immunol. Med. Microbiol. 32: 97-103.


Ward ACS, Weiser GC, Delong WJ, Frank GH. 2002. Characterization of Pasteurella spp isolated from healthy domestic pack goats and evaluation of the effects of a commercial Pasteurella vaccine. Am. J. Vet. Res. 63: 119 123.


Winkler MTC, A Doster, J-H Sur, C Jones. 2002. Analysis of bovine trigeminal ganglia following infection with bovine herpesvirus 1. Vet. Microbiol. 86: 139-155.



ABSTRACTS (2002)


Blackwood ER, Ayalew S, Confer AW. 2002. Molecular and Immunological analysis of outer membrane protein PlpE from Mannheimia haemolytica serotypes 1, 2, and 6. In 83th Annual Meeting of CRWAD. November 11-12. St. Louis, MO. Abstract nr 93.


Brady RP, Topliff CL, Kelling CL. 2002. Analyses of plasmid DNA encoding the attachment glycoprotein of bovine respiratory syncytial virus. In: Conference of Research Workers in Animal Diseases Proceedings.


Braun LJ, Braunschmidt M, Arias N, Wixon R, Wang CY, Chase CCL. 2002. Effect of genistein on bovine herpesvirus 1 and bovine viral diarrhea virus infections in vivo. In: 35th annual Conference of American Association of Bovine Practitioners. September 26-28. Rapid City, SD. p. 206.


Dunn J, Kaneene JB, Grooms D, Bolin S, Bolin C, Bruning-Fann C. 2002. The effect of infection with Mycobacterium paratuberculosis on the reliability of the caudal fold tuberculin (CFT) test and the gamma-interferon test for bovine tuberculosis in cattle. In: Proceedings of the 83th Annual Meeting of The Conference of Research Workers in Animal Diseases. November 11. St. Louis, MO. Abstract nr 47.


Elmowalid G, Ransom BL, Braun LJ, Young A, Ridpath J, Chase CCL. Bovine viral diarrhea virus interferes with macrophage surface marker expression in vitro. In: 83rd annual meeting of Conference of Research Workers in Animal Disease. November 11-12. St. Louis, MO. Abstract nr 185.


Fulton RW, Step DL, Ridpath JF, Saliki JT, Confer AW, Johnson BJ, Welsh RD, Burge LJ, Hawley RV, Payton ME. 2002. Bovine Viral Diarrhea Virus (BVDV) Persistently Infected Calves: Response to Vaccinations and Diagnoses at Necropsy. In: 45th Annual Meeting of AAVLD, October 18-22. St. Louis, MO.


Fulton RW, Step DL, Ridpath JF, Saliki JT, Confer AW, Johnson BJ, Welsh RD, Burge LJ, Hawley RV, Payton ME. 2002. Bovine Viral Diarrhea Virus (BVDV) Infections of Calves after Exposure to Persistently Infected Calves with BVDV Subtype 1b. In: 45th Annual Meeting of AAVLD. October 18-22. St. Louis, MO.


Grooms DL, Brock KV, Norby B. 2002. Performance Of Feedlot Cattle Exposed To Animals Persistently Infected With Bovine Viral Diarrhea Virus. In: Proceedings of the 83th Annual Meeting of The Conference of Research Workers in Animal Diseases. November 11. St. Louis, MO. Abstract nr 186.


Hassan, EAD, Braun LJ, Chase CCL. 2002. The effect of bovine herpesvirus 1 (BHV-1) on the organization of actin filaments and microtubules. In: 83rd annual meeting of Conference of Research Workers in Animal Disease. November 11-12. St. Louis, MO. Abstract 116-P.


Hunsaker BD, Topliff CL, Achenbach JA, Kelling CL. 2002. Back passage of a commercial modified live vaccine (MLV) strain of type 1 noncytopathic bovine viral diarrhea virus did not result in reversion to virulence. In: Conference of Research Workers in Animal Diseases Proceedings.


Lasarsky E, Fulton RW, Confer AW, Saliki JT, Briggs RE, Huchzermeier R. 2002. Bovine Coronavirus Infections in Cattle: Detection in Nasal Swabs by Antigen Capture ELISA and RT-PCR. In: CRWAD. November 10-12. St. Louis, MO.


Lu X., Rosenbusch RF. 2002. Mycoplasma bovis induces the up-regulation of VCAM-1 and ICAM-1 in bovine aortic endothelial cells. In: 83rd Annual Meeting of the Conference for Research Workers in Animal Disease. St. Louis, MO. Poster 6P.


Maheswaran SK, Malazdrewich C, Yoo HS. 2002. The role of proinflammatory
cytokines TNFa, IL-1b, and IL-8 in pneumonic mannheimiosis. In: Proceedings 8th
International Vet. Emergency and Critical Care Symposium. September 4-8.
San Antonio, Texas. P. 423-426.


Maheswaran SK, Thumbikat P. 2002. Molecular characterization of the Mannheimia haemolytica leukotoxin receptor: Controversy and conundrums. In: Proceedings of 83rd Conference for Research Workers in Animal. Disease. Abstract nr 1.


Marsh T, Chase C. 2002. Evaluation of alternate year vaccination practices in a cow-calf herd. In: 35th annual conference of American Association of Bovine Practitioners. September 26-28. Rapid City, SD. p. 172.


Miao C, Woolums AR, Brown C, Brown C, Brown Jr JC, Williams S, Zarlenga DS. 2002. Measurement of cytokine gene expression by RT-competitive PCR in BRSV vaccinated and infected calves. In: Proceedings of the Conference for Research Workers in Animal Disease. St. Louis, MO.


Prado ME, Dabo SM, Confer AW. 2002. Cloning and characterization of HasR gene homologue from Pasteurella multocida A:3. In: Proceedings of HAP2002. Banff, Alberta, Canada.


Topliff CL, Chon SK, Donis RO, Eskridge KM, Kelling CL. 2002. Translational Efficiencies of genotype 2 bovine viral diarrrhea virus field isolates using a T7 vaccinia virus expression system. In: Conference of Research Workers in Animal Diseases Proceedings.


THESIS (2002)


Elmowalid G. 2002. Unmasking the effect of bovine viral diarrhea virus on macrophage inflammatory functions. PhD Dissertation. South Dakota State University, 2002.



PEER REVIEWED PUBLICATIONS (2003)


Boudreaux CM, Corstvet RE. 2003. A novel strategy of controlling shipping fever. The Louisiana Cattleman, Official publication of the Louisiana Cattlemens Association. 36(11): 10-11.


Caverly JM, Diamond G, Gallup JM, Brogden KA, Dixon RA, Ackermann MR. Coordinated expression of tracheal antimicrobial peptide and inflammatory-response elements in the lungs of neonatal calves with acute bacterial pneumonia.
Infect Immun. 2003 May;71(5):2950-5.


Chase CCL, Chase SK, Fawcett L. 2003. Trends in the BVDV Serological Response in the United States Upper Midwest Region. Biologicals 31: 145-151.


Confer AW, Ayalew S, Montelongo M, Panciera RJ, Whitworth LC, Hammer, JD. 2003. Immunogenicity of Mannheimia haemolytica serotype 1 recombinant outer membrane protein PlpE and augmentation of a commercial vaccine. Vaccine 21: 2821-2829.


Cudd LA, Clarke CR, Clinkenbeard KD. 2003. Mannheimia haemolytica leukotoxin-induced increase in leukotriene B4 production by bovine neutrophils is mediated by sustained and excessive increase in intracellular calcium concentration. FEMS Micro. Let. 224: 85-90.


Cudd LA, Clarke CR, Clinkenbeard KD. 2003. Contribution of intracellular calcium stores to an increase in cytosolic calcium concentration induced by Mannheimia haemolytica leukotoxin. FEMS Micro. Let. 225: 23-27.


Dabo SM, Confer AW, Quijano-Blas RA. 2003. Molecular and Immunological Characterization of Pasteurella multocida A:3 OmpA: Evidence of its Role in P. multocida Interaction with Extracellular Matrix Molecules. Microb. Pathog. 35: 147-157.


Devireddy L, Zhang Y, Jones C. 2003. Cloning and initial characterization of an alternatively spliced transcript encoded by the bovine herpes virus 1 latency related (LR) gene. J. of Neurovirology. 9: 612-622.


Donovan DC, Hippen AR, Hurley DJ, Chase CCL. 2003. The role of acidogenic diets and serum antibody response against bovine respiratory viruses in Holstein steers. J. Anim. Sci. 81: 3088-3094.


Fairbanks K, Schnackel J, Chase CCL. 2003. Evaluation of a modified live virus type 1a bovine virus diarrhea vaccine (Singer strain) against a type 2 890 (Strain 890) challenge. Vet.Therapeutics. 4: 24-34.


Fajt VR, Apley MD, Roth JA, Frank DE, Brogden KA, Skogerboe TL, Shostrom VK, Chin YL. 2003. The effects of danofloxacin and tilmicosin on neutrophil function and lung consolidation in beef heifer calves with induced Pasteurella (Mannheimia) haemolytica pneumonia. J. Vet. Pharmacol. Ther. 26(3): 173-9.


Frank GH, Briggs RE, Duff GC, Hurd HS. 2003. Effect of intranasal exposure to leukotoxin-deficient Mannheimia haemolytica at the time of arrival at the feedyard on subsequent isolation of M haemolytica from nasal secretions of calves. Am. J. Vet. Res. 64(5): 580-5.


Fulton RW, Step DL, Ridpath JF, Saliki JT, Confer AW, Johnson BJ, Briggs RE, Hawley RV, Burge LJ, Payton ME. 2003. Response of calves persistently infected with noncytopathic bovine viral diarrhea virus (BVDV) subtype 1b after vaccination with heterologous BVDV strains in modified live virus vaccines and Mannheimia haemolytica bacterin-toxoid. Vaccine. 21(21-22): 2980-5.


Fulton RW, Ridpath JF, Confer AW, Saliki JT, Burge LG, Payton ME. 2003. Bovine viral diarrhoea virus antigenic diversity: impact on disease and vaccination programmes. Biologicals. 31(2): 89-95.


Fulton RW, Saliki JT, Burge LJ, Payton M. 2003. Humoral Immune Response and Assessment of Vaccine Virus Shedding in Calves Receiving Modified Live Virus Vaccines Containing Bovine Herpesvirus-1 and Bovine Viral Diarrhea Virus 1a. J.of Vet. Med. B. 50: 31-37.


Fulton RW, Ridpath JF, Confer AW, Saliki JT, Burge LJ, Payton ME. 2003. Bovine viral diarrhoea virus antigenic diversity: Impact on disease and vaccination programmes. Biologicals, 31: 89-95.


Fulton RW, Step DL, Ridpath JF, Saliki JT, Confer AW, Johnson BJ, Briggs RE, Hawley RV, Burge LJ, Payton ME. 2003. Response of Calves Persistently Infected with Noncytopathic Bovine Viral Diarrhea Virus (BVDV) Subtype 1 b after Vaccination with Heterologous BVDV Strains in Modified Live Virus Vaccines and Mannheimia haemolytica Bacterin-Toxoid. Vaccine. 21: 2980-2985.


Geiser V, Jones C. 2003. Stimulation of bovine herpesvirus 1 productive infection by the adenovirus E1A gene and the cellular transcription factor E2F4. J. of General Virology. 84: 929 938.


Jones C. 2003. Analysis of HSV 1 and BHV 1 1 latency. Clin. Microbio. Rev. 16: 79 95.


Liang D, Sainz IF, Ansari IH, Gil LH, Vassilev V, Donis RO. 2003. The envelope glycoprotein E2 is a determinant of cell culture tropism in ruminant pestiviruses. J. Gen. Virol. 84(Pt 5): 1269 1274.


Leite FS, Giles D, Atapattu, et al. 2003. Prior exposure to Mannheimia haemoloytica leukotoxin or LPS enhances b2-integrin expression by bovine neutrophils and augments leukotoxin cytotoxicity. Microb. Pathogen. 34: 267-275.


Liebler-Tenorio EM, Ridpath JF, Neill JD. 2003. Lesions and tissue distribution of viral antigen in severe acute versus subclinical acute infection with BVDV2. Biologicals. 31(2): 119-22.


Liebler-Tenorio EM, Ridpath JF, Neill JD. 2003. Distribution of viral antigen and development of lesions after experimental infection of calves with a BVDV 2 strain of low virulence. J. Vet. Diagn. Invest. 15(3): 221-32.


Lovato L, Inman M, Henderson G, Doster A, Jones C. 2003. Infection of cattle with a bovine herpesvirus 1 (BHV 1) strain that contains a mutation in the latency related gene leads to increased apoptosis in trigeminal ganglia during the transition from acute infection to latency. J of Virology. 77: 4848 4857.



Mott K, Osorio N, Jin L, Brick D, Naito J, Cooper J, Henderson G, Inman M, Jones C, Wechsler SL, Perng G-C. 2003. The BHV-1 LR genes ability to restore the high reactivation phenotype to an HSV-1 LAT null mutant appears to be due to its anti-apoptosis function. J. of General Virology. 84: 2975-2985.


Purdy CW, Straus DC, Chirase N, Ayers JR, Hoover MD. 2003. Effects of aerosolized dust in goats on lung clearance of Pasteurella and Mannheimia species. Curr. Micro. 46(3): 174.


Risatti GR, Pomp D, Donis RO. 2003. Patterns of cellular gene expression in cells infected with cytopathic or non cytopathic bovine viral diarrhea virus. Animal Biotech. 14(1): 31 49.


Thumbikat P, Briggs RE, Kannan MS, Maheswaran SK. 2003. Biological effects of two genetically defined leukotoxin mutants of Mannheimia haemolytica. Microb. Pathog. 34(5):217-226.


Vanden Bush TJ, Rosenbusch RF. 2003. Characterization of the immune response to Mycoplasma bovis lung infection. Vet. Immunol. Immunopath. 94: 23-33.


Woolums AR, Siger S, Johnson S, Gallo G, Conlon J. 2003. Rapid onset of protection following
vaccination of calves with multivalent vaccines containing modified-live or modified-live
and killed BHV-1 is associated with virus-specific interferon gamma production. Vaccine.
21: 1158-1164.


ABSTRACTS (2003)


Bolin SR. 2003. BVD: The old and the new. In: Proceedings of the Minnesota Dairy Health Conference. May 20. St. Paul, MN. p. 14-17.


Chase CCL, Elmowalid G, Braun LJ. 2003. Effect of bovine viral diarrhea virus on bovine macrophages inflammatory functions and surface marker expression in vitro. In: 9th National Symposium: Basic Aspects of Vaccines. April 30-May 2. Bethesda, MD. Abstract nr. A-4.


Chase CCL, Elmowalid G, Braun LJ, Ridpath JF. 2003. New paradigms for bovine viral diarrhea virus: understanding how BVDV interacts with the immune system. In: 36th annual conference of American Association of Bovine Practitioners. September 18-20. Columbus, OH. p. 189.


Confer AW. 2003. Pathogenesis of Bovine Bacterial Pneumonia. In: Proceedings ACVIM Forum. Charlotte, NC.


Confer AW. 2003. Appropriate Usage of Antibiotics for Disease Control. In Proceedings 2003 ASAS/ADSA Midwestern Regional Meeting. Des Moines, IA.


Dabo SM, Confer AW, Quijano-Blast, RA. 2003. Pasteurella multocida OmpA as a potential adherence factor. Proceedings 103rd Annual Meeting of American Society of Microbiology, Washington, DC. 2003


Dabo SM, Confer AW, Quijano-Blast, RA. Identification of Bartonella henselae fibronectin binding proteins. In: Proceedings 103rd Annual Meeting of American Society of Microbiology. Washington, DC.


Gopinath RS, Ambagala TC, Ambagala APN, Srikumaran S. 2003. GP96 as an adjuvant for the induction of cytotoxic T lymphocytes (CTLs) specific for bovine herpesvirus 1 (BHV 1). In: International Herpesvirus Workshop. July 26 31.


Harden TT, Paulsen DB, Godeny EK, Olcott BM, Smith SL, Triche PC, OReilly KL. 2003. Respiratory bovine coronavirus-induced pneumonia in newborn calves: a pilot study. In: South Central Branch of the American Society for Microbiology. October 24-25. New Orleans, LA.


Hassan EAD, Tigabu B, Braun LJ, Chase CCL. 2003. Reorganization of microtubules and actin filaments in bovine herpesvirus-1-infected cells and their role in virion egress. In: 22nd Annual Meeting of American Society for Virology. July 12-16. Davis, CA. Abstract nr p28-5.


Hassan EAD, Braun LJ, Chase CCL. 2003. Interaction of bovine herpesvirus-1 glycoproteins with cellular cytoskeletal elements in bovine herpesvirus-1 infected cells. In: 84th annual meeting of Conference of Research Workers in Animal Disease. November 9-11.Chicago, IL. Abstract nr 130P.


Hassan EAD, Braun LJ, Chase CCL. 2003. Effect of protein kinase inhibitors on the replication of bovine herpesvirus-1 (BHV-1). In: 84th annual meeting of Conference of Research Workers in Animal Disease. November 9-11. Chicago, IL. Abstract 174.


Hurley DJ, Pence M, Lee Y, Reber AJ, Parks RJ. 2003. Characterization of an immunological defect observed in a herd of Hereford cattle. In: Proceedings of the Conference of Research Workers in Animal Diseases. 84:102.


Inman M, Jones C. 2003. Identification and Characterization of a Novel Transcript containing an ORF that is expressed during latency, and is Antisense to the Latency Related Gene of BHV 1. In: International Herpesvirus Workshop. July 26 31.


Jiang Y, Inman M, Zhang Y, Jones C. 2003. A mutation in the latency related gene of bovine herpesvirus 1 (BHV 1) inhibits expression of proteins encoded by ORF2 and Reading Frame C during productive infection. In: International Herpesvirus Workshop. July 26 31.


Lin K-f, McArthur-Vaughan K, Rhodes GH, Gershwin LJ. 2003. Evaluation of cDNA Vaccines Coding for F or N Proteins of Bovine Respiratory Syncytial Virus: Clinical Outcome and Immune Response. In: American Society for Virology, 22nd Annual meeting. Davis, CA. July 12-16. Abstract nr W43-12.


Mott KR, Osorio N, Jin L, Brick D, Naito J, Cooper J, Henderson G, Inman M, Jones C, Wechsler SL, Perng G C. 2003. The BHV 1 LR genes ability to restore the high reactivation phenotype to an HSV 1 LAT null mutant appears to be due to its anti apoptosis function. In: ARVO meeting (vision and ophthalmology meeting). May.


Reber AJ, Okinaga T, Tanner M, Woolums A, Hurley DJ. .2003. Comparison of cytokine production assays after stimulation of bovine mononuclear cells with Staphylococcal enterotoxin B or vaccine recall antigen. In: Proceedings of the Conference of Research Workers in Animal Diseases. Astract nr. 84: 73P.



Thumbikat P, Dileepan T, Maheswaran SK. 2003. The bovine LFA-1 domain plays a critical role in mediating target cell activation but not binding of Mannheimia haemolytica leukotoxin. In: 103rd General Meeting, American Society Microbiology. Abstract nr E-101.


Woolums AR, Mason G, Brown C, Williams S, Gould J, Fox J, Sturgeon S, Sanchez S, Bartlett P, Chitwood S. 2003. Microbiologic and histopathologic findings in cases of acute interstitial pneumonia (AIP) in feedyard cattle. In: Proceedings of the Conference for Research Workers in Animal Disease (CRWAD). November. Chicago IL.


Zhang Y, Jones C. 2003. The bovine herpes virus 1 (BHV 1) immediate early gene encodes a protein (bICP0) that inhibits p53 transcriptional activity by sequestering A histone acetyltransferase (p300). In: International Herpesvirus Workshop. July 26 31.


THESES (2003)


Arias N. 2003. Analysis of Two Vaccination Programs in Dairy Cows and Their Impact on the Herd Performance and Colostrum Quality. Master of Science Thesis, South Dakota State University.


Miao C. 2003. Cytokine messenger RNA expression in calves vaccinated intranasally with modified-live bovine respiratory syncytial virus (BRSV) prior to BRSV challenge. Master of Science Thesis. University of Georgia.


Ransom B. 2003. The Effect of Bovine Herpesvirus Type 1 or Type 4 on the Functional Characteristics of Monocyte-Derived Macrophages. Master of Science Thesis. South Dakota State University.


Vandenbush A. 2003. Interactions between Mycoplasma bovis and bovine lymphocytes: characterization of a lympho-inhibitory peptide produced by Mycoplasma bovis. PhD Thesis, Iowa State University.



PEER REVIEWED PUBLICATIONS (2004)


Achenbach JE, Topliff CL, Vassilev VB, Donis RO, Eskridge KM, Kelling CL. 2004. Detection and quantitation of bovine respiratory syncytial virus using real-time quantitative RT-PCR and quantitative competitive RT-PCR assays. J. of Virological Methods. 121: 1-6.


Al-Mubarak A, Zhou Y, Chowdhury SI. 2004. A glycine rich region in the ecto domain of BHV-5 gE is important for BHV-5 neuropathogenesis. J. Virol. 78: 4806-4816.


Al-Mubarak A, Chowdhury SI. 2004. Glycoprotein I (gI)-deleted BHV-5 retains significant neurovirulence. J. Neurovirology. 10: 233-243.


Ayalew S, Confer AW, Blackwood ER. 2004. Characterization of Immunodominant and Potentially Protective Epitopes of Mannheimia haemolytica Serotype 1 Outer Membrane Lipoprotein PIpE. Infect and Immun. 72: 7265-7274.


Berry BA, Krehbiel CR, Gill DR, Confer AW, Smith RA, Montelongo M. 2004. Effects of dietary energy and starch concentrations for newly received feedlot calves: I. growth performance and health. J. Anim. Sci. 82: 837-844.


Berry BA, Krehbiel CR, Gill DR, Confer AW, Smith RA, Montelongo M. 2004. Effects of dietary energy and starch concentrations for newly received feedlot calves: II. Acute-phase protein response. J. Anim. Sci. 82: 845-850.


Bolin SR, Grooms DL. 2004. Origination and consequences of bovine viral diarrhea virus diarrhea diversity. Vet. Clin. N. Amer. Food. An. 20(1): 51.


Boyd BL, Lee TM, Kruger EF, Pinchuk LM. 2004. Bovine Viral Diarrhoea Virus Biotypes affect Fluid Phase Uptake and Mannose Receptor-Mediated Endocytosis in Bovine Monocytes. Vet. Immunol. Immunopathol. 102: 53-65.


Brady RP, Topliff CL, Kelling CL. 2004. In vitro expression of full-length and truncated bovine respiratory syncytial virus G proteins and their antibody responses in BALB/c mice. Vaccine. 22: 3762-3768.


Briggs RE, Tatum FM, inventors. 2004 Sept. 21. Construction of Pasteurella haemolytica vaccines. U.S. Patent 6,793,927.


Chase CCL, Elmowalid G, Yousif AAA. 2004. The immune response to bovine viral diarrhea virus: a constantly changing picture. Vet. Clin. Food Anim. 20:95114.


Fairbanks KK, Rinehart CL, Ohnesorge WC, Loughin MM, Chase CCL. 2004. Evaluation of fetal protection against experimental infection with type 1 and type 2 bovine viral diarrhea virus after vaccination of the dam with a bivalent modified-live virus vaccine. JAVMA. 225: 1898-2004


Fogarty Fairbanks K, Campbell J, Chase CCL. 2004. Rapid onset of protection against infectious bovine rhinotracheitis with a modified-live virus multivalent vaccine. Vet.Therapeutics. 5: 17-25.


Fulton RW, Briggs RE, Payton ME, Confer AW, Saliki JT, Ridpath JF, Burge LJ, Duff GC. 2004. Maternally derived humoral immunity to bovine viral diarrhea virus (BVDV)1a, BVDV1b, BVDV2, bovine-herpesvirus-1, parainfluenza-3 virus, bovine respiratory syncytial virus, Mannheimia haemolytica and Pasteurella multocida in beef calves, antibody decline by half-life studies and effect on response to vaccination. Vaccine. 22: 644-650.


Henderson G, Perng G-C, Nesburn AB, Wechsler SL, Jones C. 2004. The latency related (LR) gene encoded by bovine herpesvirus 1 (BHV-1) can suppress caspase 3 and caspase 9 cleavage during productive infection. J. of Neurovirology. 10: 64-70.


Henderson G, Zhang Y, Inman M, Jones D, Jones C. 2004. Infected cell protein 0 encoded by bovine herpesvirus 1 can activate caspase 3 when overexpressed in transfected cells. J. Gen. Virol. 85: 3511-3516


Inman M, Zhou J, Webb H, Jones C. 2004. Identification of a novel transcript containing a small open reading frame that is expressed during latency, and is antisense to the latency related gene of bovine herpes virus 1 (BHV-1). J. of Virology. 5438-5447.


Jiang Y, Inman M, Zhang Y, Posadas NA, Jones C. 2004. A mutation in the latency related gene of bovine herpesvirus 1 (BHV-1) inhibits expression of proteins encoded by ORF2 and Reading Frame C during productive infection. J. of Virology. 78: 3184-3189.


Kalina WV, Woolums AR, Berghaus RD, Gershwin LJ. 2004. Formalin-inactivated bovine RSV vaccine enhances a Th2 mediated immune response in infected cattle. Vaccine. 22 (11-12): 1465-74. 2004


Leite F, Atapattu D, Kuckleburg C, Schultz R, Czuprynski CJ. 2004. Incubation of bovine PMNs with conditioned medium from BHV-1 infected peripheral blood mononuclear cells increases their susceptibility to Mannheimia haemolytica leukotoxin. Vet. Immunol. Immunopathol. 103: 187-193.


Liu D, Lawrence ML, Austin FW. 2004. Specific PCR identification of Pasteurella multocida based on putative transcriptional regulator genes. J. Microbiol. Methods. 58(2): 263-267.


Lu X, Rosenbusch RF. 2004. Endothelial cells from bovine pulmonary microvasculature respond to Mycoplasma bovis preferentially with signals for mononuclear cell transmigration. Molecular Pathogenesis. 37: 253-261.


Malazdrewich CP, Thumbikat MS, Abrahamsen MS, Maheswaran SK. 2004. Pharmacological inhibition of Mannheimia haemolytica lipopolysaccharide and leukotocin-induced inflammatory cytokine expression in bovine alveolar macrophages. Microbial Pathogenesis. 36: 159-169.


Malazdrewich CP, Thumbikat MS, Maheswaran SK. 2004. Protective effects of dexamathasone in experimental bovine pneumonic pasteurellosis. Microbial Pathogenesis. 36: 227-237.


Meyerholz DK, Grubor B, Gallup JM, Lehmkuhl HD, Anderson RD, Lazic T, Ackermann MR. 2004. Adenovirus-mediated gene therapy enhances parainfluenza virus 3 infection in neonatal lambs. J. Clin. Microbiol. 42(10): 4780-4787.


Meyerholz DK, Grubor B, Fach SJ, Sacco RE, Lehmkuhl HD, Gallup JM, Ackermann MR. 2004. Reduced clearance of respiratory syncytial virus infection in a preterm lamb model.
Microbes Infect. 6(14): 1312-1319.


Qiu Z, Harms JS, Zhu J, Splitter GA. 2004. Bovine herpesvirus tegument protein VP22 enhances thymidine kinase/Ganciclovir suicide gene therapy for neuroblastomas compared to herpes simplex virus VP22. J. Virol. 78: 4224-4233.


Slack J, Thomas C, Peek SF. 2004. Pneumothorax in dairy cattle: 30 cases (1990-2003). J. Amer. Vet. Med. Assoc. 225: 732-735.


Vanden Bush TJ, Rosenbusch RF. 2004. Characterization of a lympho-inhibitory peptide produced by Mycoplasma bovis. Bioch. Biophys. Res. Comm. 315: 336-341.


Welsh RD, Dye LB, Payton ME, Confer AW. 2004. Frequency of isolation and antimicrobial susceptibilities of bacterial pathogens from bovine pneumonia: 1994-2002. J. Vet. Diag. Invest. 16: 426-431.


Woolums AR, Brown C, Brown Jr JC, Cole D, Scott M, Williams S, Miao C. 2004. Effects of a single intranasal dose of modified-live bovine respiratory syncytial virus vaccine on resistance to subsequent viral challenge in calves. Am. J. Vet. Res. 65: 363-372.



ABSTRACTS (2004):


Chase CCL, Miskimins DM, Graham T, Braun L, Steen P, Ridpath J. 2004. Evidence of bovine viral diarrhea virus persistent infection in two white-tail deer in southeastern South Dakota. In: Proceedings of the 37th annual conference of American Association of Bovine Practitioners. September 23-25. Fort Worth, TX. p. 169.


Confer AW, Fulton RW, Step DL, Johnson BJ, Ridpath JF. 2004. Viral Antigen Distribution in the Respiratory Tract of Cattle Persistently Infected with Bovine Viral Diarrhea Virus Subtype 2a. At: 47th Annual Meeting of AAVLD. October 22-24. Greensboro, NC.


Donovan DC, Barton MH, Norton N, Ely LO, Hurley DJ. 2004. Modulation of innate immunity by in vitro treatment of keukocytes with CD14, lactoferrin and IgG. In: Proceedings of the 84th CRWAD meeting. November 14-16. Chicago, IL. p. 39.


Donovan DC, Reber AJ, Parks RJ, Collier C, Ely LO, Hurley DJ. 2004. Extracellular pH alters the innate immune response by enhancing phagocytosis and decreases reactive oxygen species production. In: American Dairy Science Annual Meeting. St. Louis, MO. J. Dairy Sci. 87 (Suppl. 1): 179.


Donovan DC, Collier C, Reber AJ, Parks RJ, Hurley DJ. 2004. Extracellular pH alters immunity by decreasing the production of reactive oxygen and nitrogen species, but enhancing phagocytosis in bovine neutrophils and monocytes. In: International Conference of Production Diseases in Farm Animals. July 18-22. Michigan State University. Abstract nr A-14.


Donovan DC, Reber AJ, Parks RJ, Hurley DJ. 2004. Acidic extracellular pH enhances phagocytosis and decreases reactive oxygen species production in polymorphonuclear neutrophils and monocytes. In: 7th International Veterinary Immunology Symposium. July 25-29. Quebec City, Qc, Canada. Abstract nr WK 13.6.10 p. 415.


Fogarty-Fairbanks K, Rinehart CL, Ohnesorge WC, Loughin MM, Chase CCL. 2004. Fetal protection against BVDV type 1 or 2 heterologous challenge. In: Proceedings of the 37th annual conference of American Association of Bovine Practitioners. September 23-25. Fort Worth, TX. p.171.


Fogarty-Fairbanks K, Campbell J, Chase CCL. 2004. Subcutaneous dose of infectious bovine rhinotracheitis virus provides early protection against an intranasal challenge. In: Proceedings of the 37th annual conference of American Association of Bovine Practitioners. September 23-25. Fort Worth, TX. p. 289.


Fulton RW, Burge LJ, dOffay JM, Funk R, Weaver GD, Van Campen H, Johnson BJ. 2004. Immune Response Differences in Serums from Bovine Herpesvirus-1 Vaccinated Cattle: Depenndence of Viral Strarin. At: 47th Annual Meeting of AAVLD. October 22-24. Greensboro, NC.


Fulton RW, Ridpath JF, Ores S, Saliki JT, Burge LJ, Confer AW. 2004. Bovine Viral Diarrhea Virus (BVDV) Subtypes in Diagnostic Laboratory Accessions from Clinical and Necropsy Cases: Distribution of BVDV1a, BVDV1b, and BVDV2a Subtypes. At: 47th Annual Meeting of AAVLD. October 22-24. Greensboro, NC.


Gershwin LJ, Corbeil LB, Berghaus LJ, Arnold KF, Anderson ML. 2004. IgE and cytokine profiles in calves concurrently infected with BRSV and Histophilus somni. Presented at 7th International Veterinary Immunology Symposium. July. Quebec City, Canada.


Hunsaker BD, Steffen DJ, Topliff CL, Kelling CL. 2004. Characterization of protection in calves from systemic infection or disease by vaccination with modified-live noncytopathic bovine viral diarrhea virus type 1. At: Conference of Research Workers in Animal Disease.


Topliff, C.L., S.K.Chon, R.O. Donis, K.M. Eskridge, C.L Kelling. 2004. Translational efficiencies of the 5' untranslated region from eight genotype 2 bovine viral diarrhea virus field isolates varying in virulence. Conference of Research Workers in Animal Disease.


Johnson TK, Triche PC, OReilly KL. 2004. Immune response of newborn calves to intrabronchial infection with bovine coronavirus. In: Meeting of the Louisiana Biomedical Research Network. July 28. Baton Rouge, LA.


Klink HA, Brady RP, Topliff CL, Eskridge KM, Srikumaran S, Kelling CL. 2004. Influence of bovine respiratory syncytial virus F glycoprotein N-linked glycans on in vitro expression and on antibody responses in BALB/c mice. At: Conference of Research Workers in Animal Disease.


Nanduri B, Lawrence ML, Burgess SC. 2004. Determination of sub-MIC effects of antibiotics on Pasteurella multocida protein expression using cleavable isotope coded affinity tag reagents. In: 104th General Meeting of the American Society for Microbiology. New Orleans, LA.


Okinaga T, Hurley DJ, Woolums AR, Miao C, Zarlinga DS. 2004. Comparison of bovine cytokine gene experession as measured by competitive and real-time PCR. In: Proceedings of the 84th CRWAD meeting. November 14-16. Chicago, IL. p. 41.


Okinaga T, Hines II ME, Hurley DJ. 2004. Real-time PCR measurements of cytokine mRNA from cattle and goats. In: Proceedings of the 84th CRWAD meeting. November 14-16. Chicago, IL. p. 40


Wiggins M, Woolums A, Hurley DJ, Cole D, Sanchez S. 2004. The prevalence of Mycoplasma
bovis in a subpopulation of Georgia cattle. In: Proceedings of the 84th CRWAD meeting. November 14-16. Chicago, IL.


OReilly KL, Godeny GK, Kousoulas KG, Olcott BM, Paulsen DB, Harden TT, Smith S, Triche PC. 2004. Intrabronchial infection of newborn calves with respiratory bovine coronavirus. In: Animal Disease Research Workers of Southern States. February. Biloxi, MS.


Reber AJ, Okinaga T, Tanner M, Woolums AR, Hurley DJ. 2004. Development of immunity after vaccination with MLV or killed BVD vaccines. In: Proceedings of the 84th CRWAD meeting. November 14-16. Chicago, IL. p. 40.


Reber AJ, Okinaga T, Tanner M, Woolums A, Leard T, Milward F, Hurley DJ. 2004. Evaluation of multiple immune parameters during development of immunity after vaccination with MLV or killed BVD. In: 7th International Veterinary Immunology Symposium. Program and Book of Abstracts. July 25  30. Quebec City, Canada. Abstract nr WK.1.6.7. p. 150


DISSERTATIONS (2004):


Fogarty-Fairbanks K. 2004. New clinical applications for three USDA licensed vaccines in the prevention of infectious bovine rhinotracheitis or bovine viral diarrhea virus. Master of Science Thesis. South Dakota State University.


Hassan E. 2004. Investigation of the role of viral glycoproteins gE AND gI in bovine herpesvirus type 1 (BHV-1) pathogenesis: study of cytoskeleton and phosphorylation. PhD Dissertation. South Dakota State University.


Kalina WV. 2004. The influence of Alternaria alternate Aerosol on the Development of Immune Responses in Calves During a Primary and Secondary Bovine Respiratory Syncytial Virus Infection. PhD Dissertation. University of California, Davis.


PEER REVIEWED PUBLICATIONS (2005)


Atapattu D, Czuprynski CJ. 2005. Mannheimia haemolytica leukotoxin induces apoptosis of bovine lymphoblastoid cells (BL-3) via a caspase-9 dependent mitochondrial pathway. Infect. Immun. 73: 5504-5513.


Boudreaux CM, Corstvet RE, Cooper RK, Enright FM. 2005. Effects of cecropin B transgene expression on Mannheimia haemolytica serotype 1 colonization of the nasal mucosa of calves. Am. J. Vet. Res. 66(11): 1922-1930.


Carter JN, Gill DR, Lalman DL, Krehbiel CR, Confer AW, Smith RA, Claypool PL, McDowell LR. 2005. Vitamin E supplementation in the diet of newly arrived feedlot cattle. J. Anim. Sci. 83: 1924-1932.


Confer AW, Fulton RW, Step DL, Johnson BJ, Ridpath JF. 2005. Viral Antigen Distribution in the Respiratory Tract of Cattle Persistently Infected with Bovine Viral Diarrhea Virus Subtype 2a. Vet. Path. 42: 192-199.


Dabo SM, Confer AW. 2005. Adherence of Pasteurella multocida to fibronectin. Vet. Microbiol. 110: 265-275.


Dileepan T, Thumbikat P, Walcheck B, Kannan MS, Maheswaran SK. 2005. Recombinant expression of bovine LFA-1 and characterization of its role as the receptor for Mannheimia haemolytica leukotoxin. Microbial Pathogenesis. 38: 249-257.


Dileepan T, Kannan MS, Walcheck B, Thumbikat P, Maheswaran SK. 2005. Mapping of the binding site for Mannheimia haemolytica leukotoxin within the bovine CD18. Infection and Immunity. 73: 5233-5237.


Doyle CK, Labruna MB, Breitschwerdt EB, Tang Y, Corstvet RE, Hergarty BC, Bloch KC, Li P, Walker DH, McBride JW. 2005. Detection of medically important Ehrlichia by quantitative multicolor TaqMan real-time polymerase chain reaction of the dsb gene. J. Mol. Diagn. 7(4): 1-7.


Dunn J, Kaneene JB, Grooms D, Bolin S, Bolin C, Bruning-Fann C. 2005. Effects of positive results for Mycobacterium avium subsp. paratuberculosis as determined by microbial culture of feces or antibody ELISA on results of caudal fold tuberculin test and interferon-gamma assay for tuberculosis in cattle. Am. J. of Vet. Res. 226: 429-435.


Fulton RW, Briggs RE, Ridpath JF, Saliki JT, Confer AW, Payton ME, Duff GC, Step DL, Walker D. 2005. Transmission of bovine viral diarrhea virus 1b to susceptible and vaccinated calves by exposure to persistently infected calves. Can. J. Vet. Res. 69: 161-169.


Fulton RW, Ridpath JF, Ore S, Confer AW, Saliki JT, Burge LJ, Payton ME. 2005. Bovine viral diarrhoea virus (BVDV) subgenotypes in diagnostic laboratory accessions: Distribution of BVDV1a, 1b, and 2a subgenotypes. Vet. Microbio. 111: 35-40.


Geiser V, Jones C. 2005. Localization of sequences within the latency related gene of bovine herpesvirus 1 that inhibit mammalian cell growth. J. of Neurovirology. 11: 563-570.


Geiser V, Zhang Y, Jones C. 2005. Analysis of a bovine herpesvirus 1 (BHV-1) recombinant virus that does not express the bICP0 protein. J. of General Virology. 86: 1987-1996.


Hollis LC, Smith JF, Johnson BJ, Kapil S, Mosier DA. 2005. A comparison of serological responses when modified-live infectious bovine rhinotracheitis virus vaccine, Mannheimia haemolytica bacterin-toxoid are administered with needle-free versus conventional needle-based injection in yearling feedlot steers. The Bovine Practitioner. 39: 106-109.


Hollis LC, Smith JF, Johnson BJ, Kapil S, Mosier DA. 2005. A comparison of serological responses when modified-live infectious bovine rhinotracheitis virus vaccine, Mannheimia haemolytica bacterin-toxoid and Leptospira pomona bacterin are administered with needle-free versus conventional needle-based injection in Holstein dairy calves. The Bovine Practitioner. 39: 110-114.


Kuckleburg C, Sylte MJ, Inzana TJ, Corbeil LB, Darien B, Czuprynski CJ. 2005. Bovine platelets activated by Haemophilus somnus or its lipooligosaccharide cause endothelial cell damage in vitro. Microb. Pathogen. 38: 23-32.


Larson RL, Brodersen BW, Grotelueschen DM, Hunsaker BD, Burdett W, Brock KV, Fulton RW, Goehl DR, Sprowls RW, Kennedy JA, Lonergan GH, Dargatz DA. 2005. Consideration for bovine viral diarrhea (BVD) testing. Bov. Practitioner. 39: 96-100.


Muhammad-Tahir Z, Alocilja EC, Grooms DL. 2005. Rapid detection of bovine viral diarrhea virus as surrogate of bioterrorism agents. IEEE Sensors Journal. 5(4): 757-762.


Perez S, Inman M, Doster A, Jones C. 2005. The latency related gene encoded by bovine herpesvirus 1 (BHV-1) promotes virus growth and reactivation from latency in tonsils of infected calves. J. of Clin. Microbio. 43: 393-401.


Petit C.M, Melancon J.M, Chouljenko VN, Colgrove RC, Farzan M, Knipe D.M, Kousoulas KG. 2005. Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion. Virology. 341: 215-230.


Prado ME, Dabo SM, Confer AW. 2005. Immunogenicity of iron-regulated outer membrane proteins of Pasteurella multocida A:3 in cattle: molecular characterization of the immunodominant heme acquisition system receptor (HasR) protein. Vet. Microbiol. 105: 269-280.


Qiu Z, Zhu J, Harms JS, Friedrichsen J, Splitter GA. 2005. Bovine herpesvirus VP22 induces apoptosis in neuroblastoma cells by upregulating the expression ratio of Bax to Bcl-2. Hum. Gene Ther. 16: 101-108.


Reber AJ, Hippen AR, Hurley DJ. 2005. Ingestion of whole colostrum rapidly induces the capacity in newborn calves to stimulate and respond in one-way mixed leukocyte cultures. Am. J. Vet. Res. 66: 1854-1860.


Reeks BY, Champlin FR, Paulsen DB, Scruggs DW, Lawrence ML. 2005. Effects of sub-MIC antibiotic levels and temperature on growth kinetics and outer membrane protein expression in Mannheimia haemolytica and Haemophilus somnus. Can. J. Vet. Res. 69: 1-10.


Step DL, Confer AW, Kirkpatrick JG, Richards JB, Fulton RW. 2005. Respiratory Tract Infections in Dairy Calves from Birth to Breeding Age: Detection by Laboratory Isolations and Seroconversions. Bovine Practitioner. 39: 44-532.


Sylte MJ, Kuckleburg CJ, Corbei LB l, Inzana TJ, Bertics PJ, Czuprynski CJ. 2005. Stimulation of P2X7 enhances Haemophilus somnus lipooligosaccharide-mediated apoptosis of endothelial cells. J. Leuk. Biol. 77: 958-965.



Sylte MJ, Kuckleburg CJ, Leite FP, Inzana TJ, Czuprynski CJ. 2005. Interleukin-1 beta diminishes Haemophilus somnus¬ lipooligosaccharide-mediated apoptosis of endothelial cells. Microb. Pathogen. 39: 121-130.


Tahir ZM, Alocilja EC, Grooms DL. 2005. Polyaniline synthesis and its biosensor application.
Biosens Bioelectron. 20(8): 1690-1695.


Tatum FM, Yersin YG, Briggs RE. 2005. Construction and virulence of a Pasteurella multocida FhaB2 mutant in turkeys. Microb Pathog. 39(1-2): 9-17.


Thumbikat P, Dileepan T, Kannan MS, Maheswaran SK. 2005. Mechanisms underlying Mannheimia haemolytica leukotoxin-induced oncosis and apoptosis of bovine leukocytes. Microbial Pathogenesis. 38: 161-172.


Thumbikat P, Dileepan T, Kannan MS, Maheswaran SK. 2005. Characterization of Mannheimia (Pasteurella) haemolytica leukotoxin interaction with bovine alveolar macrophage b2 integrins. Vet. Research. September Issue.


Topliff CL, Chon SK, Donis RO, Eskridge KM, Kelling CL. 2005. In vitro and in vivo translational efficiencies of 5' untranslated region from eight genotype 2 bovine viral diarrhea virus isolates. Virology. 331: 349-356.


Woolums AR, Loneragan GH, Hawkins LL, Williams SM. 2005. Baseline management practices and animal health data reported by U.S. feedlots responding to a survey regarding acute interstitial pneumonia. Bov. Pract. 39: 116-124.


Woolums AR, Loneragan GH, Hawkins LL, Williams SM. A survey of the relationshiop between management practices and risk of acute interstitial pneumonia at U.S. feedlots. Bov Pract; 39:125-133; 2005.


Zhang Y, Jones C. 2005. Identification of functional domains within the bICP0 protein encoded by BHV-1. J. of General Virology. 86: 879-886.


Zhu J, Qiu Z, Wiese C, Ishii Y, Friedrichsen J, Rajashekara G, Splitter GA. 2005. Nuclear and mitochondrial localization signals overlap within bovine herpesvirus 1 tegument protein VP22. J. Biol. Chem. 280: 16038-16044.


ABSTRACTS (2005):


Ayalew S, Blackwood ER, Confer AW. 2005. Sequence diversity of the immunogenic outer membrane lipoprotein PIpE from Mannheimia haemolytica serotypes 1, 2 and 6. In: Proceedings 105th Annual Meeting of American Society of Microbiology. Atlanta, GA.


Dabo SM, Anderson BE, Confer AW, Gupta S. 2005. Expression, Purification and Binding Activity of B. henselae Pap 31. In: Proceedings 105th Annual Meeting of American Society of Microbiology. Atlanta, GA.


Lawrence ML. 2005. Impact of sub-MIC levels of chlortetracycline and chlortetracycline/ sulfamethazine on growth kinetics of Mannheimia haemolytica and Haemophilus somnus. Summer 2005 Academy Of Veterinary Consultants Conference. Kansas City, MO.


Nanduri B, Burgess SC, Lawrence ML. 2005. Sub-MIC concentrations of antibiotics decrease Mannheimia haemolytica leukotoxin expression. At: 105th General Meeting of the American Society for Microbiology. Atlanta, GA.


Nanduri B, Lawrence ML, Burgess SC. 2005. Proteomic profiling of M. haemolytica; a bacterial pathogen with a draft genome. At: 53rd ASMS Conference on Mass Spectrometry. San Antonio, TX.


Tigabu B, Chase CCL, Braun LJ. 2005. BVDV influences the expression of Toll-like receptors. Abstract W13-4. At: 24th Annual Meeting of American Society for Virology. June 18-22. University Park, PA.



BOOK CHAPTER (2005)


Goyal S, Ripdath JF, editors. 2005. Vaccines. In: Bovine Viral Diarrhea Virus: Diagnosis, Management and Control. Blackwell Publishing: Ames, IA. p. 209-222.



PEER REVIEWED PUBLICATIONS (2006)


Ayalew S, Blackwood ER, Confer AW. 2006. Sequence diversity of the immunogenic outer membrane lipoprotein PipE from Mannheimia haemolytica serotypes 1, 2, and 6. Vet. Microbiol. 114: 260-268.


Behling-Kelly E, Vonderheid H, Kim KS, Corbeil LB, Czuprynski CJ. 2006. Roles of cellular activation and sulfated glycans in Haemophilus somnus adherence to bovine brain microvascular endothelial cells. Infect. Immun. 74: 5311-5318.


Brock KV, McCarty K, Chase CCL, Harland R. 2006. Protection against fetal infection with either bovine viral diarrhea virus type 1 or type 2 using a non-cytopathic type 1 modified live virus vaccine. Vet. Therapeutics. 7: 27-34.


Chan D, Cohen J, Naito J, Mott KR, Osorio N, Jin L, Fraser NW, Jones C, Wechsler SL, Chuen Perng G. 2006. A mutant deleted for most of the herpes simplex virus type 1 (HSV-1) UOL gene does not affect the spontaneous reactivation phenotype in rabbits. J. of Neurovirology. 12: 5-16.


Chowdhury SI, Mahmood S, Simon J, Al-Mubarak A, Zhou Y. 2006. The Us9 gene encoded by bovine herpesvirus type 1 (BHV-1) effectively complements a Us9-null bovine herpesvirus 5 (BHV-5) for anterograde transport, neurovirulence and neuroinvasiveness in a rabbit model. J. Virol. 80: 4396-4405.


Confer AW, Ayalew S, Panciera RJ, Montelongo M, Wray JH. 2006. Recombinant Mannheimia haemolytica serotype 1 outer membrane protein PIpE enhances commercial M. haemolytica vaccine-induced resistance against serotype 6 challenge. Vaccine. 24: 2248-2255.


Fulton RW, Johnson BJ, Briggs RE, Ridpath JF, Salliki JT, Confer AW, Burge LJ, Step DL, Walker DA, Payton ME. 2006. Challenge with bovine viral diarrhea virus by exposure to persistently infected calves: Protection by vaccination and negative results of antigen testing in acutely infected calves. Can. J. for V. Res. 70: 1-127.


Fulton RW, Hessman B, Johnson BJ, Ridpath JF, Saliki J, Burge LJ, Sjeklocha D, Confer AW, Funk R, Payton ME. 2006. Evaluation of diagnostic tests used for detection of bovine viral diarrhea virus and prevalence of BVDV subtypes 1a, 1b, and 2a in persistently infected cattle entering a feedlot. J. of Am. Vet. Med. Assoc. 228: 578-584.


Jones C, Geiser V, Henderson G, Jiang Y, Meyer F, Perez S, Zhang Y. 2006. Functional analysis of bovine herpesvirus 1 (BHV-1) genes expressed during latency. Vet. Microbio. 113: 199-210.


Prado ME, Confer AW, Prado TM. 2006. Maternally-and naturally-acquired antibodies to Mannheimia haemolytica and Pasteurella multocida in beef calves. Vet. Immunol. & Immunopathol. 111: 301-307.


Reber AJ, Tanner M, Okinaga T, Woolums AR, Williams S, Ensley DT, Hurley DJ. 2006. Evaluation of multiple immune parameters during development of immunity after vaccination with modified live virus or killed bovine viral diarrhea virus vaccines. Comp. Immunol. Microbiol. & Inf. Dis. 29: 61-77.


Reber AJ, Hippen AR, Hurley DJ. 2006. Colostral whey alters the expression of activation and trafficking markers on bovine mononuclear cells in vitro. Vet. Immunol. Immunopathol. 109: 139-150.


Rogers D, Wyatt C, Walz P, Drouillard J, Mosier D. 2006. Bovine alveolar macrophage
neurokinin -1 and response to substance P. Vet. Immunol. Immunopathol. 112: 290-295.


Sylte M, Inzana T, Czuprynski CJ. 2006. Role of tumor necrosis factor in endothelial cell apoptosis caused by Haemophilus somnus lipooligosaccharide. Vet. Immunol. Immunopathol. 110: 303-309.


Zhang Y, Jiang Y, Zhou J, Geiser V, Jones C. 2006. The bovine herpes virus 1 (BHV-1) immediate early protein (bICP0) interacts with the histone acetyltransferase p300, and these interactions correlate with stimulation of gC promoter activity. J. of Gen. Virology. 87: 1843-1851.


Zimmerman A, Boots R, Valli L, Chase CCL. 2006. Maternal antibody BVDV positive calves vaccinated with a modified live bovine viral diarrhea virus (BVDV) vaccine are protected against a virulent BVDV type 2 challenge. JAVMA 228: 1757-61.