09/19/2003

PUBLICATIONS:



CALIFORNIA Leong, H., Firestone, G.L. and Bjeldanes, L.F. Cytostatic effects of 3,3‘-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-alpha expression. Carcinogenesis 22; 1809-1817, 2001.



Staub, R.E., Feng, C., Onisko, B.; Bailey, G., Firestone, G.L. and Bjeldanes, L.F. Fate of Indole-3-carbinol in MCF-7 breast cancer cells, Chem. Res. Toxicol. 15:101-109, 2002.



Hong, C., Firestone, G.L., and Bjeldanes, L.F. 3,3‘-Diindolymethane (DIM) induces a G1 cell cycle arrest and Bcl-2-mediated apoptosis in human breast cancer cells. J. Biolchem. Pharm. Biochem Pharmacol. 63: 1085-1097, 2002.



Hong, C., Kim, Hyeon-A, Firestone, G.L., and Bjeldanes, L.F. 3,3‘-Diindolylmethane (DIM) induces a G1 cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21 WAFI/CIP1 expression. Carcinogenesis 23: 1297-1305, 2002.



Leong, H., Firestone, G.L., and Bjeldanes, L.F. Potent ligand-independent estrogen receptor activation by 3,3‘-diindolymethane is mediated by cross-talk between the PKA and MAPK signaling pathways. (submitted for publication) 2002.



Winter, C.K. Electronic information resources for food toxicology. Toxicology 173: 89-96, 2002. (includes discussion of natural toxins)



Garcia, E.L., Winter, C.K. Diet and Cancer. In: Cliver, D.O. and H.P. Reimann, eds., Foodborne Diseases, 2nd Edition, Academic Press, New York (in press, November 2002).



COLORADO Bais, H.P., Walker, T.S., Schweizer, H., Vivanco, J.M. Root specific elicitation and antimicrobial activity of rosmarinic acid in hairy root cultures of sweet basil (Ocimum basilicum L.). Plant Physiology & Biochemistry (in press) November, 2002.



Walker, T.S., Bais, H.P., Schweizer, H.P., Fall, R., Vivanco, J.M. Pseudomonas aeruginosa biofilm: a protective mechanism against plant root-derived antibiotics. Proceedings of the National Academy of Sciences. (Submitted)



Park, S-W., Lawrence, C.B., Linden, J.C., Vivanco, J.M. Characterization of a novel ethylene-inducible ribosome-inactivating protein exuded from root cultures of Phytolacca americana. Plant Physiology 130: 164-178, 2002.



Park, S-W., Stevens, N., Vivanco, J.M. Enzymatic specificity of three ribosome-inactivating proteins against fungal ribosomes, and correlation with antifungal activity. Planta (in press), 2002.



Bais, H.P., Loyola-Vargas, V.M., Flores, H.E., Vivanco, J.M. Root-specific metabolism: the biology and biochemistry of underground organs. In Vitro Cell Dev. - PLANT 37: 730-741, 2001.



Vivanco, J.M., Guimaraes, R., Flores, H.E. Underground plant metabolism: the biosynthetic potential of plant roots. In: Plant Roots the Hidden Half. Y. Waisel, A. Eshel, U. Kafkafi, eds., Marcel Dekker Press, new York, pp 1045-1070, 2002.



Bais, H.P., Walker, T.S., McGrew, J.J., Vivanco, J.M. Cell size aggregation and dark conditions influence growth and production of hypericin in cell suspension cultures of Hypericum perforatum L. (St. Johns Wort). In Vitro Cell. Dev.-PLANT 38: 58-65, 2002.



Walker, T.S., Bais, H.P., Vivanco, J.M. Jasmonic acid-induced hypericin production in cell suspension cultures of Hypericum perforatum L. (St. Johns Wort). Phytochemistry 60 (3): 289-293, 2002.



Bais, H.P., Vepachedu, R., Lawrence, C.B., Stermitz, F.R., Vivanco, J.M. Isolation of a gene responsible for formation of the anti-depressive compound hypericin from St. John‘s Wort (Hypericum perforatum L.) reveals a direct and complex mode of chemical synthesis. Submitted to Nature Biotechnology.



Bais, H.P., Walker, T.S., Stermitz, F.R., Hufbauer, R.A., Vivanco, J.M. Enantiomeric dependent phytotoxic and antimicrobial activity of (1)-catechin; a rhizosecreted racemic mixture from Centaurea maculosa (spotted knapweed). Plant Physiology 128: 1173-1179, 2002.



Bais, H.P., Vepachedu, R., Gilroy, S., Vivanco, J.M. A plant invasion process mediated by root allelochemicals: ecological, physiological, signal transduction and genomics evidence. In preparation for Science, 2002.



Bais, H.P., park, S-W, Halligan, D.M., Stermitz, F.R., Vivanco, J.M. Exudation of fluorescent _-carbolines from Oxalis tuberosa L. roots. Phytochemistry (in press).



Morel, C., Stermitz, F.R., Tegos, G., Lewis, K. Submitted to J. Nat. Prod., 2002.



IDAHO Exon, J.H., South, E.H. Effects of sphingomyelin on aberrant colonic crypt foci development, colon crypt cell proliferation and immune function in an aging rat tumor model. Food and Chemical Toxicology (in press), 2002.



ILLINOIS Santell, R.C., Kieu, N. Helferich, W.G. The phytoestrogen genistin inhibits growth of estrogen-independent human breast cancer cell growth in vitro but not in vivo. J. of Nutrition 130;1665-1669, 2000.



Ju, Y.H., Carson, K., Katzenellenbogen, J., Sun, J., Choi, I.H., Katzenellenbogen, B, Helferich, W.G. Estrogenic effects of extracts from cabbage, fermented cabbage, and acidified brussel sprouts on growth of estrogen-dependent (MCF-7) and -independent (MDA 231) human breast cancer cells. J. Agric. Food Chem. 48: 4628-4634, 2000.



Allred, C.D., Allred, K.F., Ju, Y., Virant, S.M., Helferich, W.G. Soy diets containing genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose dependent manner. Cancer Research 61;5045-5050, 2001.



Allred, C.D., Ju, Y., Allred, K.F., Chang, J., Helferich, W.G. Dietary genistein stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with dietary genistein. Carcinogenesis, 22: 1667-1673, 2001.



Ju, Y-H, Allred, C.D., Allred, K.F., Karko, K.L., Helferich, W.G. Dose-response study of soy isoflavone, genistein, at physiological concentration range on the growth of estrogen-dependent human breast cancer (MCF-7) tumor implanted in athymic nude mice. Journal of Nutrition, 131 (11)2957-2962, 2001.



Ju, Y-H, Doerge, C.D., Allred, D.R., Allred, K.F., Helferich, W.G. Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) in vivo. Cancer Research 62:2472-2477, 2002.



Yellayi, S., Naaz, A., Szewczykowski, M.A., Sato, T., Woods, J.A., Chang, J., Segre, M., Helferich, W.G., Cooke, P.S. The soy phytoestrogen genistein induces thymic and immune abnormalities in mice: a potential human health hazard? Proc. Natl. Acad. Sci. 99:7616-7621, 200X.



Hilakivi-Clarke, L., Cho, E., Cabanes, A., DeAssis, S., Olivo, S., Helferich, W.G., Kuoonab, M.E., Clarke, R. Modulation of pregnancy estrogen levels by maternal dietary exposure to soy isolate or n-3 polyunsaturated fatty acid and breast cancer risk among female rat offspring. J. Clinical Cancer Research (in press), 200X.



Yellayi, S., Zakroczymski, M., Selvaraj, V., Valli, V.E., Ghanta, V., Helferich, W.G., Cooke, P.S. The phytoestrogen genistein suppresses cell-mediated immunity in mice. J. Endocrinology (in press), 2002.



Helferich, W.G., Allred, C.D., Ju, Y-H., Dietary estrogens and anti-estrogens. In: Food Toxicology, W.G. Helferich and C.K. Winter, eds., CRC Press, Boca Rotan, FL. , 2001.



Helferich, W.G. Effect of genistein on growth of human breast cancer cells in vitro and in vivo. In: Phytochemicals: A New Health Paradigm. Edited by Wayne Bidlack, 2000.



MICHIGAN Yang, G-H., Pestka, J. Vomitoxin (deoxynivalenol) -mediated inhibition of nuclear protein binding to NRE-A, an IL-2 promoter negative regulatory element, in EL-4 cells. Toxicology, 172:169-179, 2002.



Wong, S.S., Zhou, H-R., Pestka, J.J. Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP-1, NF-kB and NF-IL6 in raw 264.7 macrophage cells. J. Toxicol.Environ. Health. 65:1161-1180, 2002.



Pestka, J.J., Zhou, H-R., Jia, Q., Timmer, A.M. Dietary fish oil suppresses experimental IgA nephropathy in mice. J. Nutrition, 261-269, 2002.



Islam, Z. Moon, Y.S., Zhou, H-R., King, L.E., Fraker, P.J., Pestka, J.J. Endotoxin potentiation of trichothecene-induced lymphocyte apoptosis is mediated by up-regulation of glucocorticoids. Toxicol. Appl. Pharmacol. 180: 43-55, 2002.



Christensen, H.R., Frokiaer, H., Pestka, J.J. Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells. J. Immunol., 168 (1): 171-178, 2002.



Sugita-Konishi, Y., Pestka, J.J. Differential up-regulation of TNF-alpha, IL-6, and IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in a human macrophage model. J. Toxicol. Environ Health A. 64(8): 619-636, 2001.



Zielinski, T.L., Smith, S.A., Pestka, J.J., Gray, J.I., Smith, D.M. ELISA to quantify hexanal-protein adducts in a meat model system. J. Agric. Food Chem. 49(6): 3017-3023, 2001.



Wong, S.S., Schwartz, R.C., Pestka, J.J. Superinduction of TNF-a and IL-6 in macrophages by vomitoxin (deoxynivalenol) modulated by mRNA stabilization. Toxicology 161:139-149, 2001.



Lee, M-G. Yuan, Q-P., Hart, L.P., Pestka, J.J. Enzyme-linked immunosorbent assays of zearalenone using polyclonal monoclonal and recombinant antibodies. In: M. Trucksess and A.E. Pohland (eds.), Mycotoxin Protocols, Methods in Molecular Biology, Vol. 157: 159-170, Human Press, Totowa, NJ., 2001.



Pestka, J.J., Ha, C.L., Warner, R.W., Lee, J.H., Ustunol, Z. Effects of ingestion of yogurts containing Bifidobacterium and Lactobacillus acidophilus on spleen and Peyer‘s patch lymphocyte populations in the mouse. J. Food Prot. 64: 392-395, 2001



Zhou, H-R., Lau, A.S., Pestka, J.J. An essential role of double-stranded RNA-activated protein kinase PDR in vomitoxin-induced apoptosis in raw 264.7 cells. 41st Society of Toxicology Annual Meeting, Nashville, TN, 2002.



Islam, Z., King, L.E., Fraker, P.J., Pestka, J.J. Differential induction of apoptosis in murine lymphoid subpopulations in vivo following co-exposure to lipopolysaccharide and vomitoxin. 41st Society of Toxicology Annual Meeting, Nashville, TN, 2002.



Jia, Q., Pestka, J.J. Dietary fish oil suppresses vomitoxin-induced IgA nephropathy in the mouse. 41st Society of Toxicology Annual Meeting, Nashville, TN, 2002.



Islam, Z., King, L.E., Fraker, P.J., Pestka, J.J. Differential induction of apoptosis in murine lymphoid subpopulations in vivo following co-exposure to lipopolysaccharide and vomitoxin. 41st Society of Toxicology Annual Meeting, Nashville, TN, 2002.



Moon, Y., Pestka, J.J. Relationship of trichothecene structure to Cox-2 induction in the macrophage model. 41st Society of Toxicology Annual Meeting, Nashville, TN, 2002.



Chung, Y., Pestka, J.J. Enhancement of TNF alpha-mRNA stability by deoxynivalenol through the activation of p38 kinase. 41st Society of Toxicology Annual Meeting, Nashville, TN, 2002.



Pestka, J.J., Chung, Y., Jarvis, B.B., Tak, H. Development of antibodies to satratoxins and application to enzyme-linked immunosorbent assay. 41st Society of Toxicology Annual Meeting, Nashville, TN, 2002.



OREGON Egner, P., Bailey, G., Groopman, J., Kensler, T. Chlorphyllin reduces urinary levels of a carcinogen-DNA adduct biomarker in residents of Qidong, People‘s Republic of China in a randomized, double-blind, placebo-controlled trial. Proc. Natl. Acad. Sciences, USA, 98:14601-14606, 2001.



Stoner, G., Casto, B., Ralston, S., Roebuck, B., Pereira, C., Bailey, G. Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol. Carcinogenesis 23:265-272, 2002.



Loveland, P., Reddy, A., Pereira, C., Field, J., Bailey, G. Application of matrix solid-phase dispersion in the determination of dibenzo (a, 1) pyrene content of experimental animal diets used in a large-scale tumor study. J. Chromatog. A. 932:33-41, 2001.



UTAH Van Vleet, T.R., Bombick, D.W., Coulombe, Jr., R.A. Inhibition of human cytochrome P450 2E1 activity by nicotine, cotinine, and aqueous cigarette tar extract in vitro. Toxicological Sciences 64, 185-19, 2001.



Coulombe, R.A. Antioxidants protect turkeys against toxicity of aflatoxin. NRI Research Highlights, National Research Initiative Competitive Grants Program, United States Department of Agriculture, Cooperative State Research, Education and Extension Service. No. 6, 2001.



Van Vleet, T.R., Klein, P.J., Coulombe, Jr., R.A, Metabolism of aflatoxin B1 by normal human bronchial epithelial cells. J. Toxicology and Environmental Health, Part A, 63:101-116, 2001.



Van Vleet, T.R., Maci, K., Coulombe, Jr., R.A. Comparative aflatoxin B1 activation and cytotoxicity in human bronchial cells expressing human CYPs 1A2 and 3A4. Cancer Research 62, 105-112, 2002.



Van Vleet, T.R., Klein, P.J., Coulombe, Jr., R.A. Metabolism and cytotoxicity of aflaltoxin B1 in cytochrome P-450-expressing human lung cells. J. Toxicology and Environmental Health, Part A 65: 853-67, 2002.



Klein, P.J., Van Vleet, T.R., Hall, J.O., Coulombe, Jr., R.A. Dietary butylated hydroxytoluene protects against aflatoxicosis in turkeys. Toxicology and Applied Pharmacology 182, 11-19, 2002.



Klein, P.J., Van Vleet, T.R., Hall J.O., Coulombe, Jr., R. A. Biochemical factors underlying the age-related sensitivity of turkeys to aflatoxin B1. Comparative Biochemistry and Physiology, 132: 193-201, 2002.



Klein, P.J., Van Vleet, T.R., Hall, J.O., Coulombe, Jr., R.A. Effect of dietary butylated hydroxytoluene on aflatoxin B1-relevant metabolic enzymes in turkeys. Food and Chemical Toxicology (in press), 2002.



Van Vleet, T.R., Coulombe, Jr., R.A. Aflatoxin B1 alters expression of P43 in human lung cells. Toxicological Sciences (in press), 2002.



Klein, P.J., Hall, J.O., Coulombe, Jr., R.A. Dietary butylated hydroxytoluene protects against aflatoxicosis in turkeys, In: T. Acamovic, C.S. Stewart and T.W. Pennycott (eds.) Poisonous Plants and Related Toxins, CAB International, London (in press), 2002.



Coulombe, R.A., Rieben, W.K. Lack of apparent base sequence preference of activated pyrrolizidine alkaloid cross-links with DNA, In: T. Acamovic, C.S. Stewart and T.W. Pennycott (eds.) Poisonous Plants and Related Toxins, CAB International, London (in press), 2002.



WRRC Brandon, D.L., Friedman, M. Immunoassays of soy proteins. J. Agric. Food Chem. 50: 6635-6642, 2002.



Brandon, D.L., Bates, A.H., Binder, R.G., Montague, W.C.,Jr., Whitehand, L.C., Barker, S.A. analysis of fenbendazole residues in bovine milk by ELISA. J. Agric. Food Chem. 50: 5791-5796, 2002.



Friedman, M., Henika, P.R., Mandrell, R.E. Bactericidal activities of plant essential oils and some of their isolated constituents against Escherichia coli, Salmonella enterica, Campylobacter jejuni, and Listeria monocytogenes. J. Food Protection 65: 1545-1560, 2002.



Friedman, M. Tomato glycoalkaloids: role in the plant and in the diet. J. Agric. Food Chem. 50: 5751-5780, 2002.



Friedman, M., Henika, P.R., Mackey, B.E. Effect of feeding solanidine, solasodine and tomatidine to non-pregnant and pregnant mice. Food Chem. Toxicol. (in press), 2002.



Johnsson, L., Baxter, G.A., Crooks, S.R.H., Brandon, D.L., Elliott, C.T.E. Reduction of sample matrix effects-the analysis of benzimidazole residues in serum by immunobiosensor. Food Agric. Immunol. (in press), 2002.



Kozukue, N., Friedman, M. Tomatine, chlorophyll, _-carotene, and lycopene contents in tomatoes during growth and maturation. J. Sci. Food Agric. (in press), 2003.



Mandrell, R.E., Bates, A.H., Brandon, D.L. Monoclonal antibodies against Campylobacter jejuni and Campylobacter coli outer membrane antigens. U.S. Patent No. 6,395,879. 2002.

08/23/2004

10/25/2004

Haendel, M.A., F.A. Tilton, G.S. Bailey, and R.L. Tanguay (2004). Developmental toxicity of the dithiocarbamate pesticide sodium metam in zebrafish. Toxicol. Sci. 81(2):390-400.


Blum, C.A., Xu, M., Orner, G.A., Diaz, G.D., Li, Q., Dashwood, W.M., Bailey, G.S. and Dashwood, R.H. (2003) Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: Modulation of apoptosis, cell proliferation, and B-catenin/Tcf signaling. Mutat. Res. 523-524:217-223.

Zhang, J., Hsu, J.C., Kinseth, M.A., Bjeldanes, L.F. and Firestone, G.L. Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells. Cancer 98: 2511-2520, 2003.


Chatterji, U., Riby, J.E., Taniguchi, T., Bjeldanes, E.L., Bjeldanes, L.F.and Firestone, G.L. Indole-3-carbinol stimulates transcription of the interferon gamma receptor 1 gene and augments interferon responsiveness in human breast cancer cells. Carcinogenesis. 18: 291 302, 2003.


Leong, H., Riby, J., Firestone, G.L. and Bjeldanes, L. F. Potent ligand-independent estrogen receptor activation by 3,3-diindolylmethane is mediated by cross-talk between the PKA and MAPK signaling pathways. J. Mol. Endo. 18: 291-302, 2004.


Rieben, W.K., and Coulombe, R.A. (2004). DNA cross-linking by dehydromonocrotaline lacks apparent base sequence preference. Toxicological Sciences 80, 1-7.


Coulombe, R.A. (2003) Pyrrolizidine alkaloids in foods. Advances in Food and Nutrition Research (S.L. Taylor, Ed.). Elsevier Science Ltd., Oxford, U.K. Volume 45, pp. 61-99.


Coulombe, R.A., Klein, P.J. and J.O. Hall (2003). Butylated hydroxytoluene chemoprotection: Response to Williams. Toxicology and Applied Pharmacology 189:152.


Klein, P.J. Van Vleet, T.R., Hall, J.O. and R. A. Coulombe, Jr. (2003). Effect of dietary buylated hydroxytoluene on aflatoxin B1-relevant metabolic enzymes in turkeys. Food and Chemical Toxicology 41:671-678.


Klein, P.J., Hall, J.O. and R. A. Coulombe, Jr. (2003). Dietary butulated hydroxytoluene protects against aflatoxicosis in turkeys, in Poisonous Plants and Related Toxins (T. Acamovic, C.S. Stewart and T.W. Pennycott eds.), CAB International, London. pp. 478-483.


Coulombe, R.A., and W. K. Rieben (2003). Lack of Base Sequence Preference of Activated Pyrrolizidine Alkaloid Cross-Links with DNA, in Poisonous Plants and Related Toxins, (T. Acamovic, C.S. Stewart and T.W. Pennycott eds.) CAB International, London. pp. 26-31.


Brandon, D. L., Bates, A. H., and Fridman, M. Immunoassays of Bowman-Birk and Kunitz soybean inhibitors in infant formula. J. Food Sci. 69, 11-15, 2004.


Friedman, M. Applications of the ninhydrin reaction for analysis of amino acids, peptides, and proteins to agricultural and biomedical sciences. J. Agric. Food Chem. 52, 385-406, 2004.


Friedman, M. Effects of food processing. In: Encyclopedia of Grain Science, C. Wrigley, H. Corke and C. E. Walker, eds., Elsevier, Oxford, UK, Vol. 2, pp. 328-340, 2004.


Friedman, M. Analysis of biologically active compounds in potatoes (Solanum tuberosum), tomatoes (Lycopersicon esculentum), and Jimson weed (Datura stramonium) seeds. J. Chromatography A, 1054/1-3, 141-153 (special issue devoted to food safety).


Friedman, M., Buick, R., and Elliott, C. T. Antibacterial activities of naturally occurring compounds against antibiotic-resistant Bacillus cereus vegeative cells and spores, Escherichia coli, and Staphylococcus aureus. J. Food Protection 67, 1774-1778, 2004.


Friedman, M., Henika, P. R., Levin, C. E., and Mandrell, R. E. Antibacterial activities of essential oils and their components against Escherichia coli O157:H7 and Salmonella enterica in apple juice. J. Agric. Food Chem. 52, 6042-6048, 2004, 2004.


Han, J. S., Kozukue, N., Young, K. S., Lee, K. R., and Friedman, M. Distribution of ascorbic acid in potato tubers and in home-processed and commercial potato foods. J. Agric. Food Chem. 52, 6516-6521, 2004.


Kozukue, N., Han, J. S., Lee, K. R., and Friedman, M. Dehydrotomatine content of tomatoes. J. Agric.Food Chem. 52, 2079-2083, 2004.


Lee, K. R., Kozukue, N., Han, J. S., Park, J. H., Chang, E. Y., Baek, E. J., Chang, J. S., and Friedman, M. Glycoakaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells. J. Agric. Food Chem. 52, 2832-2839, 2004.



Cooke, P.S., Naaz, A., Heine, P.A., Zakroczymski, M.A., Saunders, PTK, Taylor, J.A., Eckel, R.H., Jensen, D.R., Helferich, W.G., and Lubahn, D.B. (2003) Effects of estrogen and phytoestrogen signaling throughestrogen receptor ER-_alpha and ER_-beta on adipose tissue in males and females. Progress in Obesity Research: 9, John Libbey and Co., Eastleigh, United Kingdom pp. 458-461.


Allred, C.A., Allred, K.F., Ju, Y.H., Doerge, D.R., Schantz, S., Korol, D., and Helferich, W.G. (2004) Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats. Carcinogenesis 25:211-218.


Muthyala, R.S., Ju, Y.H., Sheng, S., Williams, L.D., Doerge, D.R., Katzenellenbogen, B.S., Helferich, W.G., and Katzenellenbogen, J.A. (2004) Equol, a natural estrogenic metabolite from soy isoflavones: convenient synthesis and resolution of R- and S-equol and their biological activity through the estrogen receptors alpha and beta. Bioorganic & Medicinal Chemistry 12(6): 1559-1567.


Ju, Y-H, C.D. Doerge, DR, Allred, K.F., Allred, C.D. and W.G. Helferich (2002) Dietary Genistein Negates the Inhibitory Effect of Tamoxifen on Growth of Estrogen-dependent Human Breast Cancer (MCF-7) In Vivo. Cancer Research 62:2472-2477


Yellayi S., A. Naaz, M.A. Szewczykowski, T. Sato, J.A. Woods, J. Chang, M. Segre, W.G. Helferich, and P.S. Cooke (2002)., The soy phytoestrogen genistein induces thymic and immune abnormalities in mice: a potential human health hazard? Proc. Natl. Acad. Sci. 99:7616-7621.


Hilakivi-Clarke L., E. Cho, A. Cabanes, S. DeAssis, S. Olivo, W.G Helferich M.E. Kuoonab, and R.Clarke (2002) Modulation of pregnancy estrogen levels by maternal dietary exposure to soy isolate or n-3 polyunsaturated fatty acid and breast cancer risk among female rat offspring. J. Clinical Cancer Research 8:3601-3610.


M. Malik, C. Zhao, N.W. Schoene, M.M. Giusti, M.P. Moyer, B.A. Magnuson. 2003 Anthocyanin-rich extract from Aronia meloncarpa E. induces a cell cycle block in colon cancer but not normal colonic cells. Nutrition and Cancer 46 (2): 186-196.


Y. Kwon, M. Malik and B.A. Magnuson. 2004. Inhibition of colonic aberrant crypt foci by curcumin in rats is affected by age. Nutrition and Cancer 48 (1):37-43.


M. Malik and B.A. Magnuson, 2004. Rapid method for identification of chemopreventive compounds using multiplex RT-PCR for cyclooxygenase mRNA expression. Cancer Detection and Prevention. 28(4): 277-282.


Kinser, S., Q. Jia, M. Li, A. Laughter, P. Cornwell, J. C. Corton, and J. Pestka. 2004. Gene expression profiling in spleens of deoxynivalenol-exposed mice: immediate early genes as primary targets. J. Toxicol. Environ. Health A 67:1423-1441.


Pestka, J. J., H. R. Zhou, Y. Moon, and Y. J. Chung. 2004. Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox. Toxicol. Lett. 153:61-73.


Jia, Q., Y. Shi, M. B. Bennink, and J. J. Pestka. 2004. Docosahexaenoic acid and eicosapentaenoic acid, but not alpha-linolenic acid, suppress deoxynivalenol-induced experimental IgA nephropathy in mice. J. Nutr. 134:1353-1361.


Gregory, L., J. J. Pestka, D. G. Dearborn, and T. G. Rand. 2004. Localization of satratoxin-G in Stachybotrys chartarum spores and spore-impacted mouse lung using immunocytochemistry. Toxicol. Pathol. 32:26-34.


Uzarski, R. L. and J. J. Pestka. 2003. Comparative susceptibility of B cells with different lineages to cytotoxicity and apoptosis induction by translational inhibitors. J. Toxicol. Environ. Health A 66:2105-2118.


Moon, Y. and J. J. Pestka. 2003. Deoxynivalenol-induced mitogen-activated protein kinase phosphorylation and IL-6 expression in mice suppressed by fish oil. J. Nutr. Biochem. 14:717-726.


Chung, Y. J., H. R. Zhou, and J. J. Pestka. 2003. Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin). Toxicol. Appl. Pharmacol. 193:188-201.


Uzarski, R. L., Z. Islam, and J. J. Pestka. 2003. Potentiation of trichothecene-induced leukocyte cytotoxicity and apoptosis by TNF-alpha and Fas activation. Chem. Biol. Interact. 146:105-119.


Moon, Y., R. Uzarski, and J. J. Pestka. 2003. Relationship of trichothecene structure to COX-2 induction in the macrophage: selective action of type B (8-keto) trichothecenes. J. Toxicol. Environ. Health A 66:1967-1983.


Islam, Z. and J. J. Pestka. 2003. Role of IL-1(beta) in endotoxin potentiation of deoxynivalenol-induced corticosterone response and leukocyte apoptosis in mice. Toxicol. Sci. 74:93-102.


Zhou, H. R., A. S. Lau, and J. J. Pestka. 2003. Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response. Toxicol. Sci. 74:335-344.


Pestka, J. J. 2003. Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions. Toxicol. Lett. 140-141:287-295.


Bais, H.P., Park, S.W., Weir, T.L. Callaway, R.M., and Vivanco, J.M. (2004) How plants communicate using the underground information superhighway. Trends in Plant Science 9:26-32


Veluri, R., Weir, T.L., Bais, H.P., Stermitz, F.R., and Vivanco, J.M. (2004) Phytotoxic and antimicrobial activities of catechin derivatives. Journal of Agricultural and Food Chemistry 52:1077-1082


Bais, H.P., Fall, R, and Vivanco, J.M. (2004) Biocontrol efficiency of Bacillus subtilis (6051) against Pseudomonas syringae (DC3000) in Arabidopsis thaliana roots is facilitated by biofilm formation and surfactin production. Plant Physiology 134: 307-319


Park, S-W., Vepachedu, R., Owens, R.A., and Vivanco, J.M. (2004) The N-glycosidase activity of the ribosome-inactivating protein ME1 targets single-stranded regions of nucleic acids independent of sequence or structural motifs. Journal of Biological Chemistry 279: 34165-34174


Weir, T., Park, S-W., and Vivanco, J.M. (2004) Biochemical and physiological mechanisms mediated by allelochemicals. Current Opinion in Plant Biology 7:472-479


Walker, T.S., Bais, H.P., Déziel E., Schweizer H.P., Rahme L.G., Fall R., and Vivanco, J.M. (2004) Pseudomonas aeruginosa-plant root interactions: pathogenicity, biofilm formation and root exudation. Plant Physiology 134:320-331


Voss KA, Meredith FI, Bacon CW. 2003. Effect of baking and frying on the in vivo toxicity to rats of cornmeal containing fumonisins. Journal of Agricultural and Food Chemistry 51: 5546-51.


Palencia, E. Torres, O., Hagler, W., Meredith, F..I., Williams, L. D., and Riley, R.T. 2003. Total fumonisins are reduced in tortillas using the traditional nixtamalization method of Mayan communities. Journal of Nutrition 133:3200-3203


Sharma RP, He Q, Johnson VJ, Voss KA. 2003. Increased expression of CD95-ligand and other apoptotic signaling factors by fumonisin B1, a hepatotoxic mycotoxin, in livers of mice lacking tumor necrosis alpha. Cytokine 24: 226-236.


Marasas, W.F.O., Riley, R.T., Hendricks, K.A., Stevens, V.L., Sadler, T.W., Gelineau-van Waes, J., Missmer, S.A., Cabrera Valverde, J., Torres, O.L., Gelderblom, W., Allegood, J., Martínez de Figueroa, A.C., Maddox, J., Miller, J.D., Starr, L., Sullards, M.C., Roman Trigo, A.V., Voss, K.A., Wang, E., Merrill, A.H., Jr. 2004. Fumonisins disrupt sphingolipid metabolism, folate transport and development of neural crest cells in embryo culture and in vivo: A risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize? Journal of Nutrition. 134:711-716.


Williams, L.D., Meredith, F.I., and Riley, R.T. 2004. Fumonisin-ortho-Phthalaldehyde derivative is stabilized at low temperature. Journal of Chromatography (B) 806: 311-314.


Merrill, A.H., Jr., Wang, E., Liotta, D.C. and Riley, R.T. 2004. Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination. US Patent no. 6,720,184 issued 3 April, 2004.


Winter, C.K.: Exposure and dose-response modeling for food chemical risk assessment. In: R.H. Schmidt and G.E. Rodrick (eds.), Food Safety Handbook, Wiley-Interscience, Hoboken, NJ, ps. 73-88, 2003.


Winter, C.K.: Pesticides and herbicides. Toxicology. In B.L. Caballero, L. Trugo, and P. Finglas (eds), Encyclopedia of Food Sciences and Nutrition, 2nd Edition, Academic Press, San Diego, ps. 4494-4501, 2003.


Winter, C.K.: Surveillance for pesticide residues. In Watson, D.H., (ed.), Pesticide, veterinary and other residues in food. Woodhead Publishing, Cambridge, England, ps. 277-293 (2004).

11/01/2005

Park S-W, Prithiviraj B, Vepachedu R and Vivanco JM 2005. Isolation and purification of ribosome-inactivating proteins. In Plant Tissue Culture Protocols. V. M. Loyola-Vargas and F. A. Vázquez-Flota, eds. Humana Press, Totowa, New Jersey, 335  347

Prithiviraj B, Bais HP, Weir T, Suresh B, Najarro EH, Dayakar BV, Schweizer HP, and Vivanco JM 2005. Salicylic acid down regulates virulence factors of Pseudomonas aeruginosa thereby attenuating its virulence on Arabidopsis thaliana and Caenorhabiditis elegans. Infection and Immunity 73:5319-5328

Horiuchi J, Prithiviraj P, Bais H.P, Kimball BA, and Vivanco JM 2005. Soil nematodes mediate positive interactions between legume plants and rhizobium bacteria. Planta DOI: 10.1007/s00425-005-0025-y

Hompesch RW, Garcia CD, Weiss DJ, Vivanco JM, and Henry CS 2005. Analysis of natural flavonoids by microchip-micellar electrokinetic chromatography with pulsed amperometric detection. The Analyst 130:694-700.

Callaway RM, Ridenour WM, Laboski T, Weir T, and Vivanco JM 2005. Natural selection for resistance to the allelopathic effects of invasive plants. Journal of Ecology 93:576-583

Prithiviraj B, Bais HP, Jha AK, and Vivanco JM 2005. Staphylococcus aureus pathogenicity on Arabidopsis thaliana is mediated either by a direct effect of salicylic acid on the pathogen or by SA-dependent, NPR1 independent host responses. Plant Journal 42:417-432

Bais HP, Prithiviraj B, Jha AK, Ausubel FM, and Vivanco JM 2005. Root exudation of antimicrobials mediates pathogen resistance. Nature 434:217-221

Vepachedu R, Park S-W, Sharma N, and Vivanco JM 2005. Bacterial expression and enzymatic activity analysis of ME1, a ribosome-inactivating protein from Mirabilis expansa. Protein Expression and Purification 40:142-151

Vivanco JM, Cosio E, Loyola-Vargas VM, and Flores HE 2005. Los mecanismos quimicos de defensa en las plantas. Investigación y Ciencia [Scientific American Latinoamerica] 341:68-75

Prithiviraj B, Weir T, Bais HP, Schweizer HP and Vivanco JM 2005. Plant models for animal pathogenesis. Cellular Microbiology 7:315-324

Thelen GC, Vivanco JM, Newingham B, Good W, Bais HP, Landres P, Caesar A and Callaway RM 2005. Insect herbivory stimulates allelopathic exudation by an invasive plant and the suppression of natives. Ecology Letters 8:209-217

Jha AK, Bais HP and Vivanco JM 2005. Enterococcus faecalis uses mammalian virulence-related factors to exhibit potent pathogenicity in the Arabidopsis thaliana plant model. Infection and Immunity 73:464-475

Friedman M and Mottram DS (Editors) 2005. Chemistry and Safety of Acrylamide in Food, Springer, New York; Advances in Experimental Medicine and Biology, Volume 561

Friedman M 2005. Biological effects of Maillard browning products in relation to safety of acrylamide. Advances in Experimental Medicine and Biology 561, 135-156

Friedman M, Lee K R, Kim HJ, Lee IS and Kozukue N 2005. Anticarcinogenic effects of glycoakaloids from potatoes against human cervical, liver, lymphoma, and stomach cancer cells. Journal of Agricultural and Food Chemistry 53, 6162-6169

Nam SH, Choi SP, Kang MY, Kozukue N and Friedman M 2005. Antioxidative, antimutagenic, and anticarcinogenic activities of rice bran extracts in chemical and cell assays. Journal of Agricultural and Food Chemistry 53, 816-822

Nam SH, Choi SP, Kang MY, Koh H J, Kozukue N and Friedman M 2005. Bran extracts from pigmented rice seeds inhibit tumor promotion in lymphoblastoid B cells by phorbol ester. Food and Chemical Toxicology 43, 741-745

Cousin MA, Riley RT and Pestka JJ 2005. Foodborne mycotoxins: Chemistry, biology, ecology, and toxicology. in "Foodborne Pathogens: Microbiology and Molecular Biology". Pp 164-226. P. M. Fratamico and A. K. Bhunia (ed) Horizon Scientific Press, Ltd., Norfolk, UK.

Riley RT and Pestka J 2005. Mycotoxins: metabolism, mechanisms and biochemical markers. In "The Mycotoxin Blue Book" Duarte Diaz, Ed., pp 279-294. Nottingham University Press, Nottingham, UK.

Rentz SS, Meredith FI, Showker JA and Riley RT 2005. Inhibition of Sphingolipid Biosynthesis Decreases Phosphorylated ERK2 in LLC-PK1 Cells. Food and Chemical Toxicology. 43: 123-131

He Q, Riley RT, and Sharma RP 2005. Myriocin prevents fumonisin B1-induced sphingoid base accumulation in mice liver without ameliorating hepatotoxicity. Food and Chemical Toxicology 43:969-979

Gelineau-van Waes J, Starr L, Maddox JR, Aleman F, Voss KA, Wilberding J and Riley RT 2005. Maternal fumonisin exposure and risk for neural tube defects: Disruption of sphingolipid metabolism and folate transport in an in vivo mouse model. Birth Defects Research (A) 73: 487-497

Piva A, Casadei G, Pagliuca G, Cabassi E, Galvano F, Solfrizzo M, Riley RT and Diaz DE 2005. Inability of activated carbon to prevent the toxicity of culture material containing fumonisin B1 when fed to weaned piglets Journal of Animal Science 83: 1939-1947

Stauber AJ, Brown-Borg H, Liu J, Waalkes MP, Laughter A, Staben RA, Coley JC, Swanson C, Voss KA, Kopchick JJ and Corton JC 2005. Constitutive expression of peroxisome proliferator-activated receptor alpha-regulated genes in dwarf mice. Molecular Pharmacology. 67: 681-694

Humpf H-U and Voss KA 2004. Effects of food processing on the chemical structure and toxicity of fumonisin mycotoxins.Molecular Nutrition and Food Research 48:255-269

Corton JC, Apte U, Anderson SP, Limaye P, Yoon L, Latendresse J, Dunn C, Everitt JI, Voss KA, Swanson C, Kimbrough C, Wong JS, Gill SS, Chandraratna RA, Kwak M, Kensler TW, Stulnig TM, Steffensen KR, Gustafsson JA, Mehendale HM. 2004. Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors. Journal of Biological Chemistry 279: 46204-46212

Voss KA, Riley RT, and Gelineau-van Waes J 2005. Trends in fumonisin research: Recent studies on the developmental effects of fumonisins and Fusarium verticillioides. Mycotoxins 55: 91-100

Dalessandri KM, Firestone GL, Fitch MD, Bradlow HL and Bjeldanes LF 2004. Pilot study: effect of 3,3'-diindolylmethane (DIM) supplements on urinary hormone metabolites in postmenopausal women with a history of early stage breast cancer. Nutrition and Cancer 50(2): 161-167

Chang X, Tou JC, Hong C, Kim H-A, Riby J, Firestone GL and Bjeldanes LF 2005. 3,3-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice. Carcinogenesis 26(4): 771-778

Garcia HH, Brar GA, Nguyen DHH, Bjeldanes LF and Firestone GL 2005. Indole-3-carbinol (I3C) inhibits cyclin dependent kinase-2 function in human breast cancer cells by regulating the size distribution, associated cyclin E forms and subcellular localization of the CDK2 protein complex. J. Biol. Chem. 280(10): 8756-64

Xue L, Schaldach CM, Janosik T, Bergman J, and Bjeldanes LF 2005. Effects of analogs of indole-3-carbinol cyclic trimerization product in human breast cancer cells. Chem. Biol. Interact. 152(2-3): 119-29

Xue L, Firestone GL and Bjeldanes LF 2005. DIM stimulates IFNgamma gene expression in human breast cancer cells via the specific activation of JNK and p38 pathways. Oncogene. 24(14): 2343-53

Hsu JC, Zhang J, Dev A, Wing A, Bjeldanes LF. and Firestone GL 2005.
Indole-3-carbinol inhibition of androgen receptor expression and down-regulation of androgen responsiveness in human prostate cancer cells. Carcinogenesis. 2005 Jun 15; [Epub ahead of print]

Brew CT, Aronchik I, Hsu JC, Sheen JH, Dickson RB, Bjeldanes LF and Firestone GL 2005. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells. Int J Cancer. 2005 Sep 8; [Epub ahead of print]

Coulombe RA, Guarisco JA, Klein PJ and Hall JO 2005. Chemoprevention of aflatoxicosis in poultry by dietary butylated hydroxytoluene. Animal Feed Science and Technology 121: 217-225

Yip SSM and Coulombe RA Jr. 2005. Molecular cloning and expression of a novel cytochrome P450 from turkey liver with aflatoxin B1 metabolizing activity. Chem. Res. Toxicol. (submitted for publication)

Van Vleet TR, Watterson TL, Klein PJ and Coulombe RA, Jr. 2005. Aflatoxin B1 alters the expression of p53 in cytochrome P450-expressing human lung cells. Toxicological Sciences. (in press)

Rieben WK and Coulombe RA 2004. DNA cross-linking by dehydromonocrotaline lacks apparent base sequence preference. Toxicological Sciences 82, 497-503

Islam Z and Pestka JJ 2005. LPS priming potentiates and prolongs proinflammatory cytokine response to the trichothecene deoxynivalenol in the mouse. Toxicol. Appl. Pharmacol. (in press)

Smolinski AT and Pestka JJ 2005. Comparative effects of the herbal constituent parthenolide (Feverfew) on lipopolysaccharide-induced inflammatory gene expression in murine spleen and liver. J Inflamm. (Lond) 2, 6

Zhou HR, Islam Z and Pestka JJ 2005. Induction of competing apoptotic and survival signaling pathways in the macrophage by the ribotoxic trichothecene deoxynivalenol. Toxicol. Sci. 87(1), 113-122

Li M, Cuff CF and Pestka J 2005. Modulation of murine host response to enteric reovirus infection by the trichothecene deoxynivalenol. Toxicol. Sci. 87(1), 134-145

Urraca JL, ito-Pena E, Perez-Conde C, Moreno-Bondi MC and Pestka JJ 2005. Analysis of zearalenone in cereal and Swine feed samples using an automated flow-through immunosensor. J Agric. Food Chem. 53(9), 3338-3344

Jia Q and Pestka JJ 2005. Role of cyclooxygenase-2 in deoxynivalenol-induced immunoglobulin a nephropathy. Food Chem. Toxicol. 43(5), 721-728

Zhou HR, Jia Q and Pestka JJ 2005. Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the SRC family kinase Hck. Toxicol. Sci. 85(2), 916-926

Pestka JJ and Smolinski AT 2005. Deoxynivalenol: toxicology and potential effects on humans. J Toxicol. Environ. Health B Crit Rev. 8(1), 39-69

Kinser S, Li M, Jia Q and Pestka JJ 2005. Truncated deoxynivalenol-induced splenic immediate early gene response in mice consuming (n-3) polyunsaturated fatty acids. J Nutr. Biochem. 16(2), 88-95

Pestka JJ, Uzarski RL and Islam Z 2005. Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes. Toxicology 206 (2), 207-219

Allred CA, Allred KF, Ju YH, Doerge DR, Schantz S, Korol D and Helferich WG 2004. Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats. Carcinogenesis 25:211-218

Muthyala RS, Ju YH, Sheng S, Williams LD, Doerge DR, Katzenellenbogen BS, Helferich WG and Katzenellenbogen JA 2004. Equol, a natural estrogenic metabolite from soy isoflavones: convenient synthesis and resolution of R- and S-equol and their biological activity through the estrogen receptors alpha and beta. Bioorganic & Medicinal Chemistry 12(6): 1559-1567

Selvaraj V, Zakroczymski MA, Naaz A, Mukai M, Ju YH, Doerge DR, Katzenellenbogen JA, Helferich WG and Cooke PS 2004. Estrogenicity of the isoflavone metabolite equol on reproductive and non-reproductive organs in mice. Biology of Reproduction 71:966-972

Ju YH, Clausen LM, Almada AL and Helferich WG 2004. Beta$-sitosterol, $Beta-sitosterol glucoside, and a mixture of $Beta- sitosterol and $-sitosterol glucoside modulate the growth of estrogen-responsive breast cancer cells in vitro and in ovariectomized athymic mice. J. Nutr. (In Press)

Allred CA, Allred KF, Ju YH, Doerge DR and Helferich WG 2004. Soy processing influences growth of estrogen-dependent breast cancer tumors. Carcinogenesis 25(9):1649-1657

Allred CD, Twaddle NC, Allred KF, Churchwell MI, Ju YH, Helferich WG and Doerge DR 200X. Soy processing affects metabolism and disposition of dietary isoflavones in ovariectomized Balb/c mice. J. Ag and Food Chem. (In Press)

Ju YH, Fultz J, Allred KF, Doerge DR and Helferich WG 200X. Effects Of Dietary Daidzein And Its Metabolite, Equol, At Physiological Concentrations On The Growth Of Estrogen-Dependent Human Breast Cancer (MCF-7) Tumor Implanted In Ovariectomized Athymic Mice.Carcinogenesis(In Press)

Tilton SC, Givan SA, Pereira C, Bailey GS and Williams DE 2005. Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17²-estradiol and ²-naphthoflavone in rainbow trout. Toxicol. Sci. Advanced Access Sept. 28, 2005. 10.1093/toxsci/kfi341

Tilton SC, Gerwick, LG, Hendricks JD, Rosato C, Corley-Smith G, Givan SA, Bailey GS, Bayne CJ and Williams DE 2005. Use of a rainbow trout oligonucleotide microarray to examine transcriptional patterns in aflatoxin B1-induced hepatocellular carcinoma compared to adjacent liver. Toxicol. Sci. Advanced Access Sept. 1, 2005. 10.1093/toxsci/kfi309

01/12/2007

ONLY PUBLICATIONS REPORTED AT THE 2006 MEETING ARE LISTED

Allred, C. A., Allred, K.F., Ju, Y.H., Doerge, D.R., and Helferich, W.G. (2004) Soy processing influences growth of estrogen-dependent breast cancer tumors. Carcinogenesis 25(9):1649-1657

Allred, C.A., Allred, K.F., Ju, Y.H., Doerge, D.R., Schantz, S., Korol, D., and Helferich, W.G. (2004) Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats. Carcinogenesis 25:211-218.

Allred, C.D., Twaddle, N.C., Allred, K.F., Churchwell, M.I., Ju, Y.H., Helferich, W.G., and Doerge, D.R. (200X) Soy processing affects metabolism and disposition of dietary isoflavones in ovariectomized Balb/c mice. J. Ag and Food Chem. (In Press)

Brew, C.T., Aronchik, I., Hsu, J.C., Sheen, J.H., Dickson, R.B., Bjeldanes, L.F., Firestone, G.L. (2006) Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells. Int. J. Cancer. 118(4):857-68.

Chang, X., Firestone, G.L., Bjeldanes, L.F. (2006) Inhibition of growth factor-induced ras signaling in vascular endothelial cells and angiogenesis by 3,3'-diindolylmethane. Carcinogenesis. 27(3):541-50.

Coulombe, R.A., Guarisco, J.A., Klein, P.J. and J.O. Hall (2005) Chemoprevention of aflatoxicosis in poultry by dietary butylated hydroxytoluene. Animal Feed Science and Technology 121: 217-225.

Friedman, M. (2006) Nutritional evaluation of D-amino acids. In D-Amino Acids: A New Frontier in Amino Acid and Protein Research - Methods and Protocols, R. Kono and G. H. Fisher (Eds.), Nova Science Publishers, Happauge, New York, Chapter 4.

Friedman, M., Buick, R., and Elliott, C. T. (2006) Antimicrobial activities of plant compounds against antibiotic-resistant Micrococcus luteus. Int. J. Antimicrob. Agents. 28: 156-158.

Friedman, M., Henika, P. R., Levin, C. E., and Mandrell, R. W. (2006) Antimicrobial wine formulations against the foodborne pathogens Escherichia coli O157: H7 and Salmonella enterica. J. Food Sci. 71: M245-251.

Friedman, M., Henika, P. R., Levin, C. E., Mandrell, R. E., and Kozukue, N. (2006) Antimicrobial activities of tea catechins and theaflavins and tea extracts against Bacillus cereus. J. Food Prot. 69: 354-361.

Friedman, M., Levin, C. E., Choi, S.-H., Kozukue, E., and Kozukue, N. (2006) HPLC analysis of catechins, theaflavins, and alkaloids in commercial teas and green tea dietary supplements: comparison of water and 80% ethanol/water extracts. J. Food Sci. 71: C328-C337.

Gong Y, Firestone, G.L., Bjeldanes,L.F. (2006) 3,3'-Diindolylmethane (DIM) is a novel topoisomerase II{alpha} catalytic inhibitor that induces S phase retardation and mitotic delay in human hepatoma HepG2 cells. Mol Pharmacol. Mol. Pharmacol. 69(4):1320-7.

Gong, Y., Sohn, H., Xue, L,. Firestone, G.L., Bjeldanes, L.F. (2006) 3,3'-Diindolylmethane is a novel mitochondrial H(+)-ATP synthase inhibitor that can induce p21(Cip1/Waf1) expression by induction of oxidative stress in human breast cancer cells. Cancer Res. 66(9):4880-7.

Hsu JC, Dev A, Wing A, Brew CT, Bjeldanes LF, Firestone GL. (2006) Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein. Biochem Pharmacol. 2006 Sep 11; [Epub ahead of print].

Hsu, J.C., Zhang, J., Dev, A., Wing, A., Bjeldanes, L.F,. Firestone, G.L. (2005) Indole-3-carbinol inhibition of androgen receptor expression and down-regulation of androgen responsiveness in human prostate cancer cells. Carcinogenesis. 26(11): 1896-904.

Islam, Z., and Pestka, J. J. (2006). LPS priming potentiates and prolongs proinflammatory cytokine response to the trichothecene deoxynivalenol in the mouse. Toxicol. Appl. Pharmacol. 211(1), 53-63.

Islam, Z., Gray, J. S., and Pestka, J. J. (2006). p38 Mitogen-activated protein kinase mediates IL-8 induction by the ribotoxin deoxynivalenol in human monocytes. Toxicol. Appl. Pharmacol. 213(3), 235-244.

Islam, Z., Harkema, J. R., and Pestka, J. J. (2006). Satratoxin G from the black mold Stachybotrys chartarum evokes olfactory sensory neuron loss and inflammation in the murine nose and brain. Environ. Health Perspect. 114(7), 1099-1107.

Jia, Q., and Pestka, J. J. (2005). Role of cyclooxygenase-2 in deoxynivalenol-induced immunoglobulin a nephropathy. Food Chem. Toxicol. 43(5), 721-728.

Jia, Q., Zhou, H. R., Shi, Y., and Pestka, J. J. (2006). Docosahexaenoic acid consumption inhibits deoxynivalenol-induced CREB/ATF1 activation and IL-6 gene transcription in mouse macrophages. J. Nutr. 136(2), 366-372.

Ju, Y. H., Allred K.F., Allred, C.D., and Helferich, W.G. (200X) The Soy Isoflavone, Genistein, Stimulates the Growth of Human Breast Cancer Cells In Vivo in the Presence of Low Plasma Levels of Estradiol. (Submitted) Carcinogenesis

Ju, Y. H., Fultz J, Allred K.F., Doerge D.R., and Helferich, W.G. (200X) Effects Of Dietary Daidzein And Its Metabolite, Equol, At Physiological Concentrations On The Growth Of Estrogen-Dependent Human Breast Cancer (MCF-7) Tumor Implanted In Ovariectomized Athymic Mice. (In Press) Carcinogenesis

Ju, Y.H., Clausen, L.M., Almada, A.L., and Helferich, W.G. (2004) Beta$-sitosterol, $Beta-sitosterol glucoside, and a mixture of $Beta- sitosterol and $-sitosterol glucoside modulate the growth of estrogen-responsive breast cancer cells in vitro and in ovariectomized athymic mice. J. Nutr. (In Press)

Jubert, C and Bailey, G. (200x). Large-Scale Isolation of Chlorophyll a and b from Spinach by Counter-Current Chromatography. Journal of Chromatography A, (submitted).

Juneja, V. K., Thippareddi, H., and Friedman, M. (2006) Control of Clostridium perfringens in cooked ground beef by carvacrol, cinnamaldehyde, thymol, or oregano oil during chilling. J. Food Prot. 69: 1546-1551.

Juneja, V. K., Thippareddi, H., Bari, L., Inatsu, Y., Kawamoto, S., and Friedman, M. (2006) Chitosan protects cooked ground beef and turkey against Clostridium perfringens spores during chilling. J. Food Sci. 71: M236-M240.

Kinser, S., Li, M., Jia, Q., and Pestka, J. J. (2005). Truncated deoxynivalenol-induced splenic immediate early gene response in mice consuming (n-3) polyunsaturated fatty acids. J. Nutr. Biochem. 16(2), 88-95.

Kozukue, N., Han, J. S., Kozukue, E., Lee, S. J., Kim, J. A., Lee, K. R., Levin, C. E., and Friedman, M. (2005) Analysis of eight capsaicinoids in peppers and pepper-containing foods by high-performance liquid chromatography and liquid chromatography-mass spectrometry. J. Agric. Food Chem. 53: 9172-9181.

Kwon, D., Yoon, S., Carter, O., Bailey, G.S., Dashwood, R.H. (200x) Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. BioFactors, in press

Li, M., Cuff, C. F., and Pestka, J. (2005). Modulation of murine host response to enteric reovirus infection by the trichothecene deoxynivalenol. Toxicol. Sci. 87(1), 134-145.

Li, M., Cuff, C. F., and Pestka, J. J. (2006). T-2 toxin impairment of enteric reovirus clearance in the mouse associated with suppressed immunoglobulin and IFN-gamma responses. Toxicol. Appl. Pharmacol. 214(3), 318-325.

Li, M., Harkema, J. R., Islam, Z., Cuff, C. F., and Pestka, J. J. (2006). T-2 toxin impairs murine immune response to respiratory reovirus and exacerbates viral bronchiolitis. Toxicol. Appl. Pharmacol. (in press)

Mbandi, E., and Pestka, J. J. (2006). Deoxynivalenol and satratoxin G potentiate proinflammatory cytokine and macrophage inhibitory protein 2 induction by Listeria and Salmonella in the macrophage. J. Food Prot. 69(6), 1334-1339.

Muthyala, R.S., Ju, Y.H., Sheng, S., Williams, L.D., Doerge, D.R., Katzenellenbogen, B.S., Helferich, W.G., and Katzenellenbogen, J.A. (2004) Equol, a natural estrogenic metabolite from soy isoflavones: convenient synthesis and resolution of R- and S-equol and their biological activity through the estrogen receptors alpha and beta. Bioorganic & Medicinal Chemistry 12(6): 1559-567.

Nam, S. H., Choi, S. P., Kang, M. Y., Koh, H. J., Kozukue, N., and Friedman, M. (2006) Antioxidative activities of bran extracts from twenty one pigmented rice cultivars. Food Chem. 94: 613-620.

Orner GA., Roebuck BD., Dashwood RH., Bailey GS. 2006. Post-initiation chlorophyllin exposure does not modulate aflatoxin-induced foci in the liver and colon of rats. Journal of Carcinogenesis 2006, 5:6.

Pestka, J. J., and Smolinski, A. T. (2005). Deoxynivalenol: toxicology and potential effects on humans. J. Toxicol. Environ. Health B Crit Rev. 8(1), 39-69.

Pestka, J. J., Uzarski, R. L., and Islam, Z. (2005). Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes. Toxicology 206 (2), 207-219

Pestka, J., and Zhou, H. R. (2006). Toll-like receptor priming sensitizes macrophages to proinflammatory cytokine gene induction by deoxynivalenol and other toxicants. Toxicol. Sci. 92(2), 445-455.

Pratt, M. M., Reddy, A. P., Hendricks, J.D., Pereira, C., Kensler, T.W., and Bailey, G.S. (2006). The importance of carcinogen dose in chemoprevention studies: quantitative interrelationships between, dibenzo[a,l]pyrene dose, chlorophyllin dose, target organ DNA adduct biomarkers, and final tumor outcome. Carcinogenesis doi: 10.1093/carcin/bgl174

Reed, K.M., Mendoza, K.M. and R. A. Coulombe, Jr. (2006). Structure and genetic mapping of the Cytochrome P4501A5 gene in the turkey (Meleagris gallopavo). Cytogenetics and Genome Research (in press).

Riby, J.E., Xue, L., Chatterji, U., Bjeldanes, E.L., Firestone, G.L., Bjeldanes, L.F. (2006) Activation and potentiation of interferon-g signaling by 3,3-diindolylmethane in MCF-7 breast cancer cells. Mol. Pharmacol. 69(2):430-9.

Riley RT, Voss KA, Speer M, Stevens VL, Gelineau-van Waes J. (2006) Fumonisin inhibition of ceramide synthase: A possible risk factor for human neural tube defects. In, Y. Hirabayashi , A. Merrill, and Y. Igarashi (Eds) Sphingolipid Biology, pp. 345-362, Springer Verlag, Tokyo.


Riley RT, Voss KA. (2006) Differential sensitivity of rat kidney and liver to fumonisin toxicity: Organ specific differences in toxin accumulation and sphingoid base metabolism. Toxicological Science 92: 335-345.


Riley, R.T., Torres, O.A., Palencia, E. (2006) International shipping of fumonisins from maize extracts on C18 sorbent. Food Additives and Contaminants. 23: 826-832.

Selvaraj V, Zakroczymski MA, Naaz A, Mukai M, Ju YH, Doerge DR, Katzenellenbogen JA, Helferich WG, Cooke PS (2004) Estrogenicity of the isoflavone metabolite equol on reproductive and non-reproductive organs in mice. Biology of Reproduction 71:966-972.

Sharma, R.P., He, Q. and Riley, R.T. (2005) Lupus-prone NZBWF1/J mice, defective in cytokine signaling, are resistant to fumonisin hepatotoxicity despite accumulation of liver sphinganine. Toxicology 216: 59-71.

Shi, Y., and Pestka, J. J. (2006). Attenuation of mycotoxin-induced IgA nephropathy by eicosapentaenoic acid in the mouse: dose response and relation to IL-6 expression. J. Nutr. Biochem. 17(10), 697-706.

Simonich, M.T., Egner, P.E., Roebuck, B.D., Orner, G., Jubert, C., Pereira, C., Groopman, J.D., Kensler, T.W., Dashwood, R.H., Williams, D., and Bailey, G.S. (200x). Natural chlorophyll inhibits aflatoxin B1 induced multi-organ carcinogenesis in the rat. Carcinogenesis, (submitted)

Simonich, M.T., McQuistan, T., Jubert, C., Pereira, C., Hendricks, J.D., Dashwood, R.H., Williams, D., and Bailey, G.S. (200x). Natural chlorophyll inhibits dibenzo[a,l]pyrene-induced multi-organ carcinogenesis in the rainbow trout. Carcinogenesis, (submitted).

Smolinski, A. T., and Pestka, J. J. (2005). Comparative effects of the herbal constituent parthenolide (Feverfew) on lipopolysaccharide-induced inflammatory gene expression in murine spleen and liver. J. Inflamm. (Lond) 2, 6.

Staub, R.E., Onisko, B., Bjeldanes, L.F. (2006) Fate of 3,3'-diindolylmethane in cultured mcf-7 human breast cancer cells. Chem Res Toxicol. 19(3):436-42,

Sundar SN, Kerekatte V, Equinozio CN, Doan VB, Bjeldanes LF, Firestone GL. (2006) Indole-3-Carbinol (I3C) selectively uncouples expression and activity of estrogen receptor subtypes in human breast cancer cells. Mol Endocrinol. 2006 Aug 10; [Epub ahead of print].

Tilton, S.C., Hendricks, J.D., Orner, G.A., Pereira, C.B., Bailey, G.S., and Williams, D.E. (200x) Gene expression analysis during tumor enhancement by the dietary phytochemical, 3,3-diindolylmethane, in rainbow trout. (Submitted)

Urraca, J. L., ito-Pena, E., Perez-Conde, C., Moreno-Bondi, M. C., and Pestka, J. J. (2005). Analysis of zearalenone in cereal and Swine feed samples using an automated flow-through immunosensor. J. Agric. Food Chem. 53(9), 3338-3344.

Van Vleet, T.R., Watterson, T.L., Klein, P.J., and R.A. Coulombe, Jr. (2006). Aflatoxin B1 alters the expression of p53 in cytochrome P450-expressing human lung cells. Toxicological Sciences. 89, 399-407.

Vivanti, V., Finotti, E., and Friedman, M. (2006) Level of acrylamide precursors asparagine, fructose, glucose, and sucrose in potatoes sold at retail in Italy and in the United States. J. Food Sci. 71: C81-C85.

Voss KA Gelineau-van Waes, Riley RT. (2006) Fumonisins: current research trends in developmental toxicology. Mycotoxin Research 22, 61-69.

Voss KA, Liu J, Anderson SP, Dunn C, Miller JD, Owen JR, Riley RT, Bacon CW, Corton JC. (2006)Toxic effects of fumonisin in mouse liver are independent of the peroxisome proliferator-activated receptor ±. Toxicological Science 89:108-119.

Voss KA, Norred WP, Meredith FI, Riley RT, Saunders DS. (2006) Fumonisin concentration and ceramide synthase inhibitory activity of corn, masa and tortilla chips. Journal of Toxicology and Environmental Health (Part A) 69:1387-1397.

Voss KA, Riley RT, Dunn C, Corton JC. (2006) The role of tumor necrosis factor a and the peroxisome proliferator-activated receptor a in modulating the effects of fumonisin in mouse liver. Toxicology 222:165-174.

Voss KA, Riley RT, Gelineau van-Waes JB. (2005) Trends in fumonisin research: recent studies on the developmental effects of fumonisins and Fusarium verticillioides. Mycotoxins (Japan), 55:91-100.

Wang, R., Dashwood, W.M., Bailey, G.S., Williams, D.E., and Dashwood, R.H. (2006) Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in b-catenin that are independent of b-catenin mutation status. Mutation Res. (in press)

Watterson, T.L., Sorenson, J., Martin, R., and R.A. Coulombe, Jr. (200X). Effects of PM2.5 Collected from Cache Valley Utah on Genes Associated with the Inflammatory Response in Human Lung Cells. Toxicology and Applied Pharmacology. (submitted).

Williams, L.D., Glenn, A.E., Bacon, C.W., Smith, M.A.and Riley, R.T. (2006) Fumonisin production and bioavailability to maize seedlings grown from seeds inoculated with Fusarium verticillioides and grown in natural soils. Journal of Agricultural and Food Chemistry. 54: 5694-5700.

Xiao S, Anderson SP, Swanson C, Bahnemann R, Voss KA, Stauber AJ, Corten JC. (2006) Activation of peroxisome proliferator activated receptor ± (PPAR ±) enhances apoptosis in mouse liver. Toxicological Science 92: 368-377.


Xue L, Li M, Pestka JJ, Firestone GL, Bjeldanes LF. (200X) 3,3-Diindolylmethane is a novel immunomodulator that activates cytokine production, lymphocyte proliferation, and reovirus clearance. J Nutrition [submitted]


Yip, S.S.M. and R.A. Coulombe, Jr. (2006) Molecular cloning and expression of a novel cytochrome P450 from turkey liver with aflatoxin B1 metabolizing activity. Chemical Research in Toxicology 19:30-37.


Yu, Z., Loehr, C., Fischer, K., Louderback, M., Kreuger, S., Dashwood, R., Kerkvliet, N., Pereira, C., Jennings-Jee, J., Dance, S., Miller, M., Bailey, G. and Williams, D. (2006). In utero exposure of mice to dibenzo(a,l)pyrene produces lymphomas in the offspring: Role of the aryl hydrocarbon receptor. Cancer Res. 66:755-762.

Zhou, H. R., Islam, Z., and Pestka, J. J. (2005). Induction of competing apoptotic and survival signaling pathways in the macrophage by the ribotoxic trichothecene deoxynivalenol. Toxicol. Sci. 87(1), 113-122.

Zhou, H. R., Jia, Q., and Pestka, J. J. (2005). Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the SRC family kinase Hck. Toxicol. Sci. 85(2), 916-926.

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