02/15/2023

See attached minutes

02/15/2024

There were 71 new publications by W5122 members in 2022-2023 period, addressing the effects of bioactive nutrients on health and chronic disease risk, basic insights into nutrient metabolism, and the development of new methodology and technologies for studying these processes in humans and novel model systems.  Publications are listed below with W5122 group members in boldfaced text.

1. Pratibha V Nerurkar*, Jennifer Yokoyama^a, Kramer Ichimura^a , Shannon Kutscher^a, Jamie Wong^a, Harry C Bittenbender, Youping Deng. Medium Roasting and Brewing Methods Differentially Modulate Global Metabolites, Lipids, Biogenic Amines, Minerals, and Antioxidant Capacity of Hawai'i-Grown Coffee (Coffea arabica). Metabolites, 2023 Mar 10;13(3):412. doi: 10.3390/metabo13030412.


2. Gallegos-Ibanez, D, Jurado-Molina, J, Wedwitschka, H, Delgado E, Nelles, M.; Stinner, W. 2023. Ensiling of invasive Elodea sp., a novel aquatic biomass feedstock for the sustainable biogas production: effects of wheat straw and silage additives on silage quality and methane production. ACS Agricultural Science & Technology, DOI: 10.1021/acsagscitech.3c00043. 


3. Sapkota G, Delgado E, VanLeeuwen DF. Holguin OF, Flores N, Yao S. 2023. Preservation of Phenols, Antioxidant Activity, and Cyclic Adenosine Monophosphate in Jujube (Ziziphus jujuba Mill.) Fruits with Different Drying Methods. MDPI – Plants 12, 1804. https://doi.org/10.3390/plants12091804.


4. Rodriguez Borbon, MI, Sohn, H, Delgado E, Fuqua, DO, Rodríguez Medina, A, Tlapa, D, Baez Lopez, Y. 2023. Shelf-Life Assessment on European Cucumber based on Accelerated Temperature-Humidity Stresses. Appl. Sci. 2023, 13, 2663. https://doi.org/10.3390/app13042663.


5. Sapkota G, Delgado E, VanLeeuwen DF. Holguin O, Flores N, Heyduck R, Yao S. 2023. Dynamics of Nutrients in Jujube (Ziziphus jujuba Mill.) at Different Maturity Stages, Cultivars, and Locations. HortScience 58(2):155–163. https://doi.org/10.21273/HORTSCI16880-22


6. Thais M. Ramos, Hanna Louvau, Heesun Kim, Maria L. Marco, and Erin DiCaprio. 2022. Leveraging the COVID-19 fermentation trend to enhance nutrition and food safety extension efforts. Journal of Extension 60(4). Article 15. 10.34068/joe.60.04.15


7. Zhengyao Xue and Maria L Marco. 2022. Improved assessments of bulk milk microbiota composition via sample preparation and DNA extraction methods. PLoS One 15:17(9) e0267992


8. Colin Hill, Daniel J Tancredi, Christopher J Cifelli PhD, Joanne L Slavin, Jaime Gahche, Maria L Marco, Robert Hutkins, Victor L Fulgoni III, Daniel Merenstein, and Mary Ellen Sanders. 2023. Positive health outcomes associated with live microbe intake from foods, including fermented foods, assessed using NHANES database. Journal of Nutrition 153(3):1143-1149.


9. Eric Stevens and Maria L Marco. 2023. Bacterial extracellular electron transfer in plant and animal ecosystems. FEMS Microbiology Reviews 19:47(3).


10. Javad Barouei, Alice Martinic, Zach Bendiks, Darya Mishchuk, Dustin Heeney, Carolyn M Slupsky, and Maria L Marco. 2023. Type 2-resistant starch and Lactiplantibacillus plantarum NCIMB 8826 result in additive and interactive effects in diet-induced obese mice. Nutrition Research 118:12-28.


11. Shuangping, Zhi-Feng Zhang, Jieqi Mao, Zhilei Zhou, Jing Zhang, Caihong Shen, Songtao Wang, Maria L Marco, Jian Mao. 2023. Integrated meta-omics approaches reveal Saccharopolyspora as the core functional genus in huangjiu fermentations NPJ Biofilms and Microbiomes. 9:65.


12. Eric T. Stevens, Wannes Van Beeck, Benjamin Blackburn, Sara Tejedor-Sanz, Alycia R. M. Rasmussen, Mackenzie E. Carter, Emily Mevers, Caroline M. Ajo-Franklin, and Maria L. Marco. Lactiplantibacillus plantarum uses ecologically relevant, exogenous quinones for extracellular electron transfer. mBio 14(6):e0223423.


13. Maier MLV, Siddens LK, Pennington JM, Uesugi SL, Labut E, Vertel EA, Anderson KA, Tidwell LG, Tilton SC, Ognibene TJ, Turteltaub KW, Smith JN, Williams DE. 2023. Impact of Phenanthrene Co-Administration on the Toxicokinetics of Benzo[a]pyrene in Humans. UPLC-Accelerator Mass Spectrometry Following Oral Microdosing. Chemico-Biological Interactions. 382:110608. doi: 10.1016/j.cbi.2023.110608. PMID: 37369263


14. Rude CI, Tidwell LG, Tilton SC, Waters KM, Anderson KA, Tanguay RL. 2023. Coupling Environmental Whole Mixture Toxicity Screening with Unbiased RNA-Seq Reveals Site-Specific Biological Responses in Zebrafish. Toxics. 11(3). doi: 10.3390/toxics11030201. PMCID: PMC10053777.


15. Vermillion Maier ML, Siddens LK, Pennington JM, Uesugi SL, Tilton SC, Vergel EA, Anderson KA, Tidwell LG, Ognibene TJ, Turteltaub KW, Smith JN, Williams DE. 2023. Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3’-Diindolylmethane (DIM) or Brussels sprouts. Appl. Pharmacol. 460:116377. doi: 10.1016/j.taap.2023.116377. PMCID: PMC9946811. (4.219)


16. Rivera BN, Ghetu C, Chang Y, Truong L, Tanguay RL, Anderson KA, Tilton SC. 2022. Leveraging multiple data streams for prioritization of mixtures for hazard characterization. Toxics: Risk Assessment on Toxicity of Chemical Mixtures. 10:651. doi.org/10.3390/toxics10110651. PMCID: PMC9699527.


17. St Mary L, Truong L, Bieberich AA, Fatig RO 3rd, Rajwa B, Tanguay RL. 2023. Comparative analysis between zebrafish and an automated live-cell assay to classify developmental neurotoxicant chemicals. Toxicol Appl Pharmacol. 2023 Oct 1;476:116659. doi: 10.1016/j.taap.2023.116659.


18. Green AJ, Truong L, Thunga P, Leong C, Hancock M, Tanguay RL, Reif DM. 2023. Deep autoencoder-based behavioral pattern recognition outperforms standard statistical methods in high-dimensional zebrafish studies. 2023 Sep 17:2023.09.13.557544. doi: 10.1101/2023.09.13.557544.


19. Dasgupta S, LaDu JK, Garcia GR, Li S, Tomono-Duval K, Rericha Y, Huang L, Tanguay RL. 2023. A CRISPR-Cas9 mutation in sox9b long intergenic noncoding RNA (slincR) affects zebrafish development, behavior, and regeneration. oxicol Sci. 2023 Jul 28;194(2):153-166. doi: 10.1093/toxsci/kfad050.


20. McClure RS, Rericha Y, Waters KM, Tanguay RL. 2023. 3' RNA-seq is superior to standard RNA-seq in cases of sparse data but inferior at identifying toxicity pathways in a model organism. Front Bioinform. 2023 Jul 27;3:1234218. doi: 10.3389/fbinf.2023.1234218.


21. Wilson LB, Moran IL, Anderson KA, Tanguay RL. 2023. Advances in PAH mixture toxicology enabled by zebrafish. Curr Opin Toxicol. 2023 Jun;34:100392. doi: 10.1016/j.cotox.2023.100392.


22. Henderson TD, Choi J, Leonard SW, Head B, Tanguay RL, Barton CL, Traber MG. 2023. Chronic Vitamin E Deficiency Dysregulates Purine, Phospholipid, and Amino Acid Metabolism in Aging Zebrafish Skeletal Muscle. Antioxidants (Basel). 2023 May 26;12(6):1160. doi: 10.3390/antiox12061160.


23. Nguyen BD, Stevens BL, Elson DJ, Finlay D, Gamble JT, Kopparapu PR, Tanguay RL, Buermeyer AB, Kerkvliet NI, Kolluri SK. 2023. 11-Cl-BBQ, a select modulator of AhR-regulated transcription, suppresses lung cancer cell growth via activation of p53 and p27^Kip1. FEBS J. 2023 Apr;290(8):2064-2084. doi: 10.1111/febs.16683.


24. Elson DJ, Nguyen BD, Bernales S, Chakravarty S, Jang HS, Korjeff NA, Zhang Y, Wilferd SF, Castro DJ, Plaisier CL, Finlay D, Oshima RG, Kolluri SK. 2023. Induction of Aryl Hydrocarbon Receptor-Mediated Cancer Cell-Selective Apoptosis in Triple-Negative Breast Cancer Cells by a High-Affinity Benzimidazoisoquinoline. ACS Pharmacol Transl Sci. 2023 Jun 7;6(7):1028-1042. doi: 10.1021/acsptsci.2c00253.


25. Elson DJ, Nguyen BD, Korjeff NA, Wilferd SF, Puig-Sanvicens V, Sang Jang H, Bernales S, Chakravarty S, Belmar S, Ureta G, Finlay D, Plaisier CL, Kolluri SK. 2023. Suppression of Ah Receptor (AhR) increases the aggressiveness of TNBC cells and 11-Cl-BBQ-activated AhR inhibits their growth. Biochem Pharmacol. 2023 Sep;215:115706. doi: 10.1016/j.bcp.2023.115706.


26. Elson DJ, Kolluri SK. 2023. Tumor-Suppressive Functions of the Aryl Hydrocarbon Receptor (AhR) and AhR as a Therapeutic Target in Cancer. Biology (Basel). 2023 Mar 30;12(4):526. doi: 10.3390/biology12040526.


27. Yang L, Marney L, Magana AA, Choi J, Wright K, Mcferrin J, Gray NE, Soumyanath A, Stevens JF, Maier CS. 2023. Quantification of Caffeoylquinic Acids and Triterpenes as Targeted Bioactive Compounds of Centella asiatica in Extracts and Formulations by Liquid Chromatography Mass Spectrometry. J Chromatogr Open. 2023 Nov 27;4:100091. doi: 10.1016/j.jcoa.2023.100091.


28. Yang L, Stanisheuski S, Song Z, Bracha S, Maier CS. 2023. Top-down mass spectrometry for characterizing the low molecular weight proteome of canine osteosarcoma cell phenotypes. Eur J Mass Spectrom (Chichester). 2023 Oct;29(5-6):313-325. doi: 10.1177/14690667231202766.


29. Newman NK, Zhang Y, Padiadpu J, Miranda CL, Magana AA, Wong CP, Hioki KA, Pederson JW, Li Z, Gurung M, Bruce AM, Brown K, Bobe G, Sharpton TJ, Shulzhenko N, Maier CS, Stevens JF, Gombart AF, Morgun A. 2023. Reducing gut microbiome-driven adipose tissue inflammation alleviates metabolic syndrome. 2023 Sep 21;11(1):208. doi: 10.1186/s40168-023-01637-4.


30. Holvoet H, Long DM, Yang L, Choi J, Marney L, Poeck B, Maier CS, Soumyanath A, Kretzschmar D, Strauss R. 2023. Chlorogenic Acids, Acting via Calcineurin, Are the Main Compounds in Centella asiatica Extracts That Mediate Resilience to Chronic Stress in Drosophila melanogaster. 2023 Sep 16;15(18):4016. doi: 10.3390/nu15184016.


31. Kundu P, Paraiso IL, Choi J, Miranda CL, Kioussi C, Maier CS, Bobe G, Stevens JF, Raber J. 2023. Xanthohumol improves cognition in farnesoid X receptor-deficient mice on a high-fat diet. Dis Model Mech. 2022 Nov 1;15(11):dmm049820. doi: 10.1242/dmm.049820.


32. Zhang J, Urriola PE, Naeve SL, Shurson GC, Chen C. Counteracting Roles of Lipidic Aldehydes and Phenolic Antioxidants on Soy Protein Oxidation Defined by a Chemometric Survey of Solvent and Mechanically Extracted Soybean Meals. Antioxidants 12, 1419 (2023)


33. Guse K, Sharma A, Weyenberg E, Davison S, Ma Y, Choi Y, Johnson AJ, Chen C, Gomez A. Regular Consumption of Lacto-fermented Vegetables has Greater Effects on the Gut Metabolome Compared with the Microbiome. Gut Microbiome, 4: e11 (2023)


34. Trudeau M, Mosher W, Tran H, de Rodas B, Karnezos P, Urriola PE, Gomez A, Saqui-Salces M, Chen C, Shurson GC. Experimental facility had a greater effect on growth performance, gut microbiome, and metabolome in weaned pigs than feeding diets containing subtherapeutic levels of antibiotics: a case study. PLOS ONE 18: e0285266 (2023)


35. Kim J, Park M, Ahn E, Mao Q, Chen C, Ryu S, Jeon B. Stimulation of Surface Polysaccharide Production under Aerobic Conditions Confers Aerotolerance in Campylobacter jejuni. Microbio Spectr. 11: e0376122 (2023)


36. Guo Y, Wang L, Hanson A, Urriola PE, Shurson GC, Chen C. Identification of Protective Amino Acid Metabolism Events in Nursery Pigs Fed Thermally Oxidized Corn Oil. Metabolites 13: 103 (2023)


37. Liu J, Huang L, An J, Y Ma, Cheng Y, Zhang R, Peng P, Wang Y, Addy M, Chen P, Chen C, Liu Y, Huang G, Ruan R. Application of High-Pressure Homogenization to Improve Physicochemical and Antioxidant Properties of Almond Hulls. Journal of Food Process Engineering. e14235 (2023)


38. Meng J, Abu YF, Zhang Y, Zhou Y, Xie Y, Yan Y, Tao J, Ramakrishnan S, Chen C, Roy S. Opioid‐induced microbial dysbiosis disrupts CPT‐11 metabolism and increases gastrointestinal toxicity in a murine model. Br J Pharmacol. 180:1362-1378 (2023)


39. Bu F, Feyzi S, Nayak G, Mao Q, Kondeti VSSK, Bruggeman P, Chen C, Ismail BP. Investigation of novel cold atmospheric plasma sources and their impact on the structural and functional characteristics of pea protein. Innovative Food Science & Emerging Technologies 83: 103248 (2023)

40. Maslin, L.A., B.R. Weeks, R.J. Carroll, D.H. Byrne, and D. Turner. 2022.  Chlorogenic acid and quercetin in a diet with fermentable fiber influence multiple processes involved in DSS-induced ulcerative colitis but do not reduce injury. Nutrients 14:3706.  doi.org/10.3390/nu14183706.  PMID 36145086


41. Turner, N.D.   Cancer health concerns.  Food Science.  https://doi.org/10.1016/B978-0-323-85125-1.00142-3


42. Conran, N., M. Lambert, and D. Turner. 2023.  Introduction to the thematic issue:  Recognition of women leaders in Science.  Experimental Biology and Medicine 247:2173-2175.


43. Omar AK, Li Puma LC, Whitcomb LA, Risk BD, Witt AC, Bruemmer J, Winger QA, Bouma GJ, Chicco AJ. High-fat diet during pregnancy promotes fetal skeletal muscle fatty acid oxidation and insulin resistance in an ovine model Am J Physiol Reg Integr Comp Physiol; 325:R523, 2023. PMID: 37642284


44. Liu W, LeBar K, Roth K, Pang J, Ayers J, Chicco AJ, Puttlitz CM, Wang, Z. Alterations of biaxial viscoelastic properties of the right ventricle in pulmonary hypertension development in rest and acute stress conditions. Front Bioeng Biotechnol. 2023 May 30. doi: doi.org/10.3389/fbioe.2023.1182703.


45. Parsons AM, Rajendran RR, Whitcomb LA, Bouma GJ, Chicco AJ. Characterization of trophoblast mitochondrial function and responses to testosterone treatment in ACH-3P cells. Placenta 137:70, 2023. PMID: 37087951


46. Giovana D. Catandi GC, Cheng M, Chicco AJ, Chen T, Carnevale EM. L-carnitine enhances developmental potential of bovine oocytes matured under high lipid concentrations in vitro. Animal Repro Sci 252:107249, 2023.


47. Chicco AJ, Zilhaver PT, Whitcomb LA, Fresa KJ, Izon CS, Gonzalez-Franquesa A, Dometita C, Irving BA, Garcia-Roves PM. Resolving the Rotenone Paradox: elucidating the complexity of multi-substrate respirometry protocols. MitoFit Preprints 2022.17. https://doi.org/10.26124/mitofit:2022-0017


48. Chatfield KC, Sparagna GC, Specht KS, Whitcomb L, Omar A, Wolfe LA, Chicco AJ. Long-chain fatty acid oxidation and respiratory complex I deficiencies distinguish Barth Syndrome from idiopathic pediatric cardiomyopathy. J Inher Metab Dis 45(1):111-124, 2022. PMID: 34821394


49. Merlin AC, Gonzalez K, Mockler S, Perez Y, Jia UA, Chicco AJ, Ullevig SL, Chung E. Post-weaning dietary intervention modulates the effects of maternal and postnatal high-fat and high-sucrose diet on cardiometabolic health in male adult offspring. Metabolites 12(6):563, 2022. PMID: 35736495


50. Wang E, Whitcomb LA, Chicco AJ, Wilson JW. Transient absorption spectroscopy and imaging of redox in muscle mitochondria. Biomedical Optics Express 13(4): 2103–2116, 2022; PMID: 35519286


51. Wang E, Specht KS, Chicco AJ, Wilson JW. High repetition-rate transient absorption spectroscopy of respiratory supercomplexes. J Phys Chem B 126(7):1404-1412, 2022; PMID: 35166549


52. Catandi GD, LiPuma LC, Obeidat YM, Maclellan LJ, Broeckling CD, Chen T, Chicco AJ, Carnevale EM. Oocyte metabolic function, lipid composition, and developmental potential are altered by diet in older mares. Reproduction 163(4): 183, 2022.


53. Zhai C, Li Puma LC, Chicco AJ, Omar A, Delmore AJ, Geornaras I, Speidel SE, Holt TN, Thomas MG, Enns RM, Nair MN. Pulmonary arterial pressure in fattened Angus steers at moderate altitude influences early postmortem mitochondria functionality and meat color during retail display. Journal of Animal Science 100(2):skac002, 2022. PMID: 35015873


54. Shivaram, K.B., Bhatt, P., Verma M.S., Clase, K., Simsek, H.* Bacteriophage-based biosensors for detection of pathogenic microbes in wastewater (Accepted: 26 July 2023) Science of the Total Environment


55. Gopalakrishnan, S., Thomas, R.,^§ Sedaghat, S.,^§ Krishnakumar, A., Khan, S., Meyer, T., Ajieren, H., Nejati, S., Wang, J., Verma, M.S., Irazoqui, P., Rahimi, R.* (2023) Smart capsule for monitoring inflammation profile throughout the gastrointestinal tract. Biosensors and Bioelectronics: X 14: 100380 DOI: 10.1016/j.biosx.2023.100380.


56. Centeno-Martinez, R.U., Mohan, S., Davidson, J.L., Schoonmaker, J.P., Ault, A., Verma, M.S., Johnson, T.A.* (2023) The bovine nasal fungal community and associations with bovine respiratory disease. Frontiers in Veterinary Science 10: 1165994 DOI: 10.3389/fvets.2023.1165994


57. Kamel, M.S., El-Sayed, A.A., Munds, R.A., Verma, M.S.* (2023) Interactions between Humans and Dogs during the COVID-19 Pandemic: Recent Updates and Future Perspectives. Animals 13:524 DOI: 3390/ani13030524.


58. Wang, J., Ranjbaran, M., Ault, A., Verma, M.S.* (2023) A loop-mediated isothermal amplification assay to detect Bacteroidales and assess risk of fecal contamination. Food Microbiology 110:104173 DOI: 1016/j.fm.2022.104173.


59. Nolasco E^, Baraka E^, Yang J, Ciftci N. O, Majumder K* (2024). In-vitro bio-accessibility and antioxidant activity of commercial standard and enriched whole egg compounds influenced by production and domestic cooking practices. Food Chemistry, 430, 136948. doi: 1016/j.foodchem.2023.136948


60. Guha S^, Majumder K* (2024). Efficacy of Great Northern beans-derived bioactive compounds in reducing vascular inflammation. Food Bioscience, 57, 103524. doi: 1016/j.fbio.2023.103524


61. Nolasco E^, Krassovskaya, I., Hong K., Hansen K^., Alvarez S., Obata T., & Majumder K* (2023). Sprouting alters metabolite and peptide contents in the gastrointestinal digest of soybean and enhances in-vitro anti-inflammatory activity. Journal of Functional Foods, 109, 105780. doi: 1016/j.jff.2023.105780


62. Newton A^, Majumder K* (2023) Germination and Simulated Gastrointestinal Digestion of Chickpea (Cicer arietinum L.) in Exhibiting In Vitro Antioxidant Activity in Gastrointestinal Epithelial Cells. Antioxidants, 12(5), 1114. doi: 3390/antiox12051114


63. Kar A^, Guha S^, Subbiah J, Majumder K* (2023) Effect of Radiofrequency Processing on the Structural and Bio-functional Properties of Egg White Proteins. Food Chemistry, 404, 134533. doi: 10.1016/j.foodchem.2022.134533


64. Sly B, Weir TL, Cunningham-Sabo L, Leisz S, Stull VJ, Melby CL (2023) Increasing household diet diversity and food security in rural Rwanda using small-scale nutrition- sensitive agriculture: A community-level study. Nutrients 15, 3137; https://doi.org/10.3390/nu15143137 IF:5.717


65. Ecton KE, Graham EL, Risk BD, Brown GD, Stark GC, Wei Y, Trikha SRJ, Weir TL, Gentile CL (2023) Toll-like receptor 4 deletion partially protects mice from high fat diet-induced arterial stiffness despite perturbation to the gut microbiota. Front Microbiomes 2:1095997. doi: 10.3389/frmbi.2023.1095997


66. Ventura M, Holland ME, Bartlett-Smith M, Chaparro JM, Prenni JE, Patz JA, Paskewitz A, Weir TL, Stull VJ (2023) Suitability of maize crop residue fermented by Pleurotus ostreatus as feed for edible crickets: growth performance, micronutrient content, and iron bioavailability. Frontiers Nutr. 10.3389/fnut.2023.1157811


67. Woolf EK, Terwood JD, Litwin NS, Vazquez AR, Lee SY, Ghanem N, Michell KA, Smith BT, Grabos LE, Ketelhut NB, Bachman NP, Smith ME, Le Savec M, Rao S, Gentile CL, Weir TL, Rodriguez-Mateos A, Seals DR, Dinneno FA, Johnson SA (2023) Daily blueberry consumption for 12 weeks improves endothelial function in postmenopausal women with above-normal blood pressure through reductions in oxidative stress: a randomized controlled trial. Food & Function. DOI: 10.1039/d3fo00157a.


68. Weir TL (2023) Grand Challenges: Actualizing the Potential of the Gut of Microbiome to Address Global Nutrition Challenges. Front Microbiomes. https://doi.org/10.3389/frmbi.2023.1146827


69. Stull VJ and Weir TL (2023) Chitin and omega-3 fatty acids in edible insects have underexplored benefits for the gut microbiome and human health. Nature Foods 4, 283–287.


70. Stull VJ, Wilson JW, Weir TL (2022) Making a Meal Out of Bugs. Food Science and Technology 36 (2): 24-28.


71. Weir TL (2024). Probiotics. Pp 475-480 In: Health Professional’s Guide to Dietary Supplements. (ed. Wallace T) Academy of Nutrition and Dietetics, Chicago, Illinois, USA.

03/14/2025

Publications:

There were 77 new publications by W5122 members in 2023-2024 period, addressing the effects of bioactive nutrients on health and chronic disease risk, basic insights into nutrient metabolism, and the development of new methodology and technologies for studying these processes in humans and model systems.  Publications are listed below with W5122 group members in boldfaced text. 

1. Briana M. Nosal, Staci Thornton, Alexey Melnik, Ali Lofti, Manije Darooghegi Mofrad, Alexander Aksenov, Elaine Choung-Hee Lee and Ock K. Chun. Blackcurrant anthocyanins attenuate estrogen deficiency-induced bone loss through modulating microbial-derived short-chain carboxylic acids and phytoestrogen metabolites in peri- and early postmenopausal women. Metabolites 2024, 14, 541. https://doi.org/10.3390/metabo14100541


2. Mao Q, Shi X, Ma Y, Lu Y, Chen C. Characterization of Urinary N-Acetyltaurine as a Biomarker of Hyperacetatemia in Mice. Metabolites. 14: 322 (2024). https://doi.org/10.3390/metabo14060322

1. Heidari F, Øverland M, Hansen JØ, Mydland LT, Urriola PE, Chen C, Shurson GC, Hu B. Enhancing the nutritional value of canola meal through solid culture with Pleurotus ostreatus. Animal Feed Science and Technology. 309: 115893 (2024) https://doi.org/10.1016/j.anifeedsci.2024.115893


2. Ravelo AD, Ferm P, Guo Y, Omontese BO, Morley PS, Chen C, Noyes NR, Caixeta LS. Using a multi-omics approach to explore potential associations with rumen content and serum of cows with different milk production levels based on genomic predicted transmitting ability for milk and phenotypic milk production. PloS one. 19: e0305674 (2024) doi: 10.1371/journal.pone.0305674


3. Trudeau M, Mosher W, Tran H, de Rodas B, Karnezos TP, Urriola PE, Gomez A, Saqui-Salces M, Chen C, Shurson GC. Growth Performance, Metabolomics, and Microbiome Responses of Weaned Pigs Fed Diets Containing Growth-Promoting Antibiotics and Various Feed Additives. Animals. 14: 60 (2024) DOI: 10.3390/ani14010060


4. Onarman Umu ÖC, Mydland LT, Chen C, de Nanclares MP, Shurson GC, Urriola PE, Sørum H, Øverland M. Integrated multi-omics approach reveals novel associations in the rapeseed diet–microbiota–host axis in pigs. ISME communications. 4: ycae061 (2024) DOI: 10.1093/ismeco/ycae061


5. Yang J, Gourley GR, Gilbertsen A, Chen C, Wang L, Smith K, Namenwirth M, Yang L. High Glucose Levels Promote Switch to Synthetic Vascular Smooth Muscle Cells via Lactate/GPR81. Cells 13: 236 (2024), https://doi.org/10.3390/cells13030236


6. Duddeck KA, Petersen TE, Adkins HJ, Smith AH, Hernandez S, Wenner SJ, Yao D, Chen C, Li W, Fregulia P, Larsen A, Jang YD. Dose-Dependent Effects of Supplementing a Two-Strain Bacillus subtilis Probiotic on Growth Performance, Blood Parameters, Fecal Metabolites, and Microbiome in Nursery Pigs. Animals. 14: 109 (2024) DOI: 10.3390/ani14010109

9. Quintero Quiroz, J, Velazquez, V, Torres, JD, Ciro, G, Delgado, E, Rojas, J. 2024. Effect of the structural modification of plant proteins as microencapsulating agents of bioactive compounds from annatto seeds (Bixa Orellana L.). Foods. 13(15), 2345; https://doi.org/10.3390/foods13152345.


10. Paśko P, Galanty A, Dymerski T, Kim YM, Park YS, Cabrales-Arellano P, Velazquez Martinez V, Delgado E, Gralak M, Deutsch J, Barasch D, Nemirovski A, Gorinstein S. 2024. Physicochemical and Volatile Compounds Analysis of Fruit Wines Fermented with Saccharomyces cerevisiae: FTIR and Microscopy Study with a Focus on Anti-inflammatory Potential. International Journal of Molecular Sciences 25, 5627. https://doi.org/10.3390/ijms25115627.


11. Martínez Ávalos, JF, Gamero Barraza, JI. Delgado, E, Guerra Rosas, MI, Gómez Aldapa, CA. Medrano Roldán, H. Reyes Jáquez, D. 2024. Study of molecular dynamic interactions during the optimized extrusion processing of corn (Zea mays) and substandard bean (Phaseolus vulgaris). Food Chemistry Advances 4, 100723. https://doi.org/10.1016/j.focha.2024.100723.


12. Gamero-Barraza, JI, Pámanes-Carrasco, GA, Delgado, E, Cabrales-Arellano, CP, Medrano-Roldán, H, Gallegos-Ibáñez, D, Wedwitschka, H, Reyes Jáquez, D. 2024. Computational modelling of extrusion process temperatures on the interactions between black soldier fly larvae protein and corn flour starch. Food Chemistry: Molecular Science 8, 2024. https://doi.org/10.1016/j.fochms.2024.100202.


13. Paśko P, Galanty A, Ramos-Zambrano E, Martinez Ayala, AL, Delgado E, Gdula – Argasińska J, Zagrodzki P, Podsiadły P, Deutsch J, Gorinstein S. 2024. Pseudocereal oils, authenticated by Fourier transform infrared spectroscopy, and their chemopreventive properties. Plant Foods for Human Nutrition.


14. Gaucin Gutiérrez, S.C., Rojas-Contreras, J.A., Zazueta-Álvarez, D.E., Delgado, E., Vázquez Ortega, P.G., Medrano Roldán, H., Reyes Jáquez, D. 2024. Exploration of In Vitro Voltage Production by a Consortium of Chemolithotrophic Microorganisms Using Galena (PbS) as a Sulphur Source. Clean Technologies, 6(1), 62-67. https://doi.org/10.3390/cleantechnol6010005.


15. Chloe Christensen, Car Reen Kok, Cheryl L Harris, Nancy Moore, Jennifer L Wampler, Weihong, Zhuang, Steven S Wu, Robert Hutkins, Jacques Izard, Jennifer M. Auchtung. Microbiota, metabolic profiles and immune biomarkers in infants receiving formula with added bovine milk fat globule membrane: a randomized, controlled trial, Frontiers Nutrition (2024) 11:1465174


16. Nancy D. Turner, Tiffany L. Weir, and Jacques Izard. Intersection of Diet, Intestinal Microbiota and Their Metabolites on Cancer Prevention. Frontiers in Nutrition (2024) 10:1358428


17. Road map Contributors (Jacques Izard as a contributor to all 3 technical themes “Health and Medicine” “Food and Nutrition”, and “Environmental Control and Life Support”); Engineering Biology Space Health, An Innovative Research Road Map; Engineering Biology Research Consortium (EBRC) Publisher (2024)


18. Arghya Mukherjee, Samuel Breselge, Eirini Dimidi, Maria L Marco, and Paul D Cotter. 2023. Fermented foods and gastrointestinal health: underlying mechanisms. Nature Reviews Gastroenterology & Hepatology. 21:248–266.


19. Lynne V McFarland, Gail Hecht, Mary E Sanders, Debra A Goff, Ellie J C Goldstein, Colin Hill, Stuart Johnson, Maryam R Kashi, Ravina Kullar, Maria L Marco, Daniel J Merenstein, Mathieu Millette, Geoffrey A Preidis, Eamonn M Quigley, Gregor Reid, Seppo Salminen, Jason C Sniffen, Harry Sokol, Hania Szajewska, Daniel J Tancredi, Kristin Woolard. 2023. Recommendations to improve quality of probiotic systematic reviews with meta-analyses: Developed by expert Delphi consensus. JAMA Network Open. 6(12):e2346872.


20. Maany Ramanan, Glen Fox, and Maria L. Marco. 2024. Beer for live microbe delivery. Journal of Functional Foods. 113:105987.


21. Mateus L.P. Lemos, Guilherme M. Leite, Liliane P. Santana, Nelquides B. Vianaa, Wydemberg J. Araújo, Wannes Van Beeck, Maria L. Marco, Anderson M. Zanine, Edson M. Santos, Celso J.B. Oliveira. 2024. Bacterial community dynamics of spineless cactus silage during fermentation and aerobic stability. Bioresource Technology Reports. 25:101762


22. Jee-Yon Lee, Connor R. Tiffany, Scott P. Mahan, Matthew Kellom, Andrew W.L. Rogers, Henry Nguyen, Eric T. Stevens, Hugo L.P. Masson, Kohei Yamazaki, Maria L. Marco, Emiley A. Eloe-Fadrosh, Peter J. Turnbaugh, and Andreas J. Baumler. 2024. High fat intake sustains sorbitol intolerance after antibiotic-mediated clostridia depletion from the gut microbiota. Cell. 87(5):1191-120


23. Glory Bui, Cristina Torres-Fuentes, Matteo M Pusceddu, Mélanie G Gareau, and Maria L Marco. 2024. Milk and Lacticaseibacillus casei BL23 effects on intestinal responses in a murine model of colitis. American Journal of Physiology and Gastrointestinal Liver Physiology. 326(6):G659-G675..


24. Lei Wei, Dana Wong, Tina Jeoh, Maria L. Marco. 2024. Intestinal delivery of encapsulated bacteriocin peptides in cross-linked alginate microcapsules. Food Research International. 118:114473.


25. Hisham Hussan, Mohamed R. Aly, Victoria Lyo, Amy Webb, Maciej Pietrzak, Jiangjiang Zhu, Fouad Choueiry, Hong Li, Bethany P. Cummings, Maria L. Marco, Valentina Medici, and Steven K. Clinton. 2024. Concentrations of fecal secondary bile acids and their metabolizing microbial enzymes: a pilot study. Obesity Surgery. 34: 3420–3433.


26. Sabina Fijan, Polona Fijan, Lei Wei, and Maria L. Marco. 2024. Health benefits of kimchi, sauerkraut and other fermented foods of the genus Brassica. Applied Microbiology. 4(3), 1165-1176.


27. Colvin V, Bramer LM, Rivera BN, Pennington JM, Waters KM, Tilton SC. 2024. Modeling PAH mixture interactions in a human in vitro organotypic respiratory model. Int. J. Mol. Sci. 25(8), 4326. doi.org/10.3390/ijms25084326. PMCID: PMC11050152.


28. Valdez R, Rivera BN, Chang Y, Pennington JM, Fischer KA, Lohr CV, Tilton SC. 2024. Assessing susceptibility for polycyclic aromatic hydrocarbon toxicity in an in vitro 3D respiratory model for asthma. Frontiers in Toxicology, Special Issue “Linking Environmental Exposure to Toxicants and Chronic Disease”. 6:1287863. doi.org/10.3389/ftox.2024.1287863. PMCID: PMCID11066177.


29. Maier MLV, Siddens LK, Pennington JM, Uesugi SL, Labut E, Vertel EA, Anderson KA, Tidwell LG, Tilton SC, Ognibene TJ, Turteltaub KW, Smith JN, Williams DE. 2023. Impact of Phenanthrene Co-Administration on the Toxicokinetics of Benzo[a]pyrene in Humans. UPLC-Accelerator Mass Spectrometry Following Oral Microdosing. Chemico-Biological Interactions. 382:110608. doi: 10.1016/j.cbi.2023.110608. PMID: 37369263.


30. Kim, T., Esmaili, E., Athalye, S.M., Matos, T., Hosseini, M., Verma, M.S., and Ardekani, A.M.* (2024) Acoustofluidic device focusing viral nanoparticles for Raman microscopy. Sensors and Actuators B: Chemical 136438 DOI: 10.1016/j.snb.2024.136438


31. Wang, J., Kaur, S., Kayabasi, A., Ranjbaran, M., Rath, I., Benschikovski, I., Raut, B., Ra, K., Rafiq, N., Verma, M.S.* (2024) A portable, easy-to-use paper-based biosensor for rapid in-field detection of fecal contamination on fresh produce farms Biosensors and Bioelectronics: 116374. DOI: 10.1016/j.bios.2024.116374


32. Kamel, M.S., Davidson, J.L., Verma, M.S.* (2024) Strategies for Bovine Respiratory Disease (BRD) Diagnosis and Prognosis: A Comprehensive Overview Animals: 14(4): 627. DOI: 10.3390/ani14040627


33. Wang, J.,§ Ranjbaran, M.,§ Verma, M.S.* (2024) Bacteroidales as a Fecal Contamination Indicator in Fresh Produce Industry: A Baseline Measurement. Journal of Environmental Management: 351:119641 DOI: 10.1016/j.jenvman.2023.119641


34. Marney LC, Choi J, Alcazar Magana A, Yang L, Techen N, Alam MN, Brandes M, Soumyanath A, Stevens JF, Maier CS. Liquid chromatography-mass spectrometry quantification of phytochemicals in Withania somnifera using data-dependent acquisition, multiple-reaction-monitoring, and parallel-reaction-monitoring with an inclusion list. Front Chem. 2024 Jul 17;12:1373535. doi:10.3389/fchem.2024.1373535. PMID: 39100918; PMCID: PMC11294917.


35. Rowe K, Gray NE, Zweig JA, Law A, Techen N, Maier CS, Soumyanath A, Kretzschmar D. Centella asiatica and its caffeoylquinic acid and triterpene constituents increase dendritic arborization of mouse primary hippocampal neurons and improve age-related locomotion deficits in Drosophila. Front Aging. 2024 Jul 11;5:1374905. doi: 10.3389/fragi.2024.1374905. PMID: 39055970; PMCID: PMC11269084.


36. Gray NE, Hack W, Brandes MS, Zweig JA, Yang L, Marney L, Choi J, Magana AA, Cerruti N, McFerrin J, Koike S, Nguyen T, Raber J, Quinn JF, Maier CS, Soumyanath A. Amelioration of age-related cognitive decline and anxiety in mice by Centella asiatica extract varies by sex, dose and mode of administration. Front Aging. 2024 May 6;5:1357922. doi: 10.3389/fragi.2024.1357922. PMID: 38770167; PMCID: PMC11102990.


37. Alcázar Magaña A, Vaswani A, Brown KS, Jiang Y, Alam MN, Caruso M, Lak P, Cheong P, Gray NE, Quinn JF, Soumyanath A, Stevens JF, Maier CS. Integrating High-Resolution Mass Spectral Data, Bioassays and Computational Models to Annotate Bioactives in Botanical Extracts: Case Study Analysis of asiatica Extract Associates Dicaffeoylquinic Acids with Protection against Amyloid-β Toxicity. Molecules. 2024 Feb 13;29(4):838. doi: 10.3390/molecules29040838.


38. Jamieson PE, Smart EB, Bouranis JA, Choi J, Danczak RE, Wong CP, Paraiso IL, Maier CS, Ho E, Sharpton TJ, Metz TO, Bradley R, Stevens JF. Gut enterotype-dependent modulation of gut microbiota and their metabolism in response to xanthohumol supplementation in healthy adults. Gut Microbes. 2024 Jan-Dec;16(1):2315633. doi: 10.1080/19490976.2024.2315633. Epub 2024 Feb 15. PMID:38358253; PMCID: PMC10878022.


39. Yang L, Marney L, Magana AA, Choi J, Wright K, Mcferrin J, Gray NE, Soumyanath A, Stevens JF, Maier CS. Quantification of Caffeoylquinic Acids and Triterpenes as Targeted Bioactive Compounds of Centella asiatica in Extracts and Formulations by Liquid Chromatography Mass Spectrometry. J Chromatogr Open. 2023 Nov 27;4:100091. doi: 10.1016/j.jcoa.2023.100091. Epub 2023 Jul 8. PMID: 37789901; PMCID: PMC10544816.


40. Holvoet H, Long DM, Yang L, Choi J, Marney L, Poeck B, Maier CS, Soumyanath A, Kretzschmar D, Strauss R. Chlorogenic Acids, Acting via Calcineurin, Are the Main Compounds in Centella asiatica Extracts That Mediate Resilience to Chronic Stress in Drosophila melanogaster. Nutrients. 2023 Sep 16;15(18):4016. doi: 10.3390/nu15184016. PMID: 37764799; PMCID: PMC10537055.


41. Newman NK, Zhang Y, Padiadpu J, Miranda CL, Magana AA, Wong CP, Hioki KA, Pederson JW, Li Z, Gurung M, Bruce AM, Brown K, Bobe G, Sharpton TJ, Shulzhenko N, Maier CS, Stevens JF, Gombart AF, Morgun A. Reducing gut microbiome-driven adipose tissue inflammation alleviates metabolic syndrome. Microbiome. 2023 Sep 21;11(1):208. doi: 10.1186/s40168-023-01637-4. PMID: 37735685; PMCID: PMC10512512.


42. Li, H., Liu, L., Fan, H., Li, M., Luo, P., Zhou, Y., Lu, K., Zhu, Q., Wu, J. Antioxidant and anti-inflammatory peptides in dry-fermented sausages fermented with Staphylococcus simulans QB7. Food and Function, 2024, 15(20), 10339 - 10349. doi: 10.1039/d4fo03659j


43. Djenar, N. S., Fulazzaky, M. A., Rinaldi, K., Santoso, B., Sulaeman, S. A., Mardiah, M., Fan, H., Yulianthina, S. Evaluation of a Gluten-Based Edible Film Incorporated with Beetroot Extract and ZnO Nanoparticles as an Active Food Packaging System. ACS Food Science and Technology, 2024, 4(6), 1511-1526. doi: 10.1021/acsfoodscitech.4c00123


44. Wang, Z., Fan, H., Wu, J. Food-derived up-regulators and activators of angiotensin-converting enzyme 2: A review. Journal of Agricultural and Food Chemistry, 2024, 72(23), 12896-12914. doi: 10.1021/acs.jafc.4c01594


45. Wang, Z., Wang, C. F., Fan, H., Bao, X., Ashkar, F., Li, L., Kiang, T. K.L., Wu, J. Bioavailability and metabolism of bioactive peptide IRW with angiotensin-converting enzyme 2 (ACE2) upregulatory activity in spontaneously hypertensive rats. Journal of Agricultural and Food Chemistry, 2024, 72(15), 8606-8617. doi: 10.1021/acs.jafc.4c01052


46. Fan, H., Shang, N., Davidge, S. T., Wu, J. Chicken muscle-derived ACE2-upregulating peptide VVHPKESF reduces blood pressure associated with the ACE2/Ang (1-7)/MasR axis in spontaneously hypertensive rats. Molecular Nutrition and Food Research, 2024, 68(5). doi: 10.1002/mnfr.202300524


47. Li, H., Fan, H., Wang, Z., Zhu, Q., Wu, J. Effect of simulated gastrointestinal digestion on antioxidant, and anti-inflammatory activities of bioactive peptides generated in sausages fermented with Staphylococcus simulans QB7. Food Science and Human Wellness, 2024, 13(3), 1662-1671. doi: 10.26599/FSHW.2022.9250145


48. Tait C, Chicco AJ, Naug D. Brain energy metabolism as an underlying basis of slow and fast cognitive phenotypes in honeybees J Exp Biol 227 (17):247835, 2024. PMID: 39092671


49. Fresa KJ, Catandi GD, Whitcomb LA, Gonzalez-Castro RA, Chicco AJ, Carnevale EM. Adiposity in mares induces insulin dysregulation and mitochondrial dysfunction which can be mitigated by nutritional intervention. Sci Rep 14:13992, 2024. PMID: 38886475


50. Catandi GD, Fresa KJ, Cheng MH, Whitcomb LA, Broekling CD, Chen TW, Chicco AJ, Carnevale EM. Follicular metabolic alterations are associated with obesity in mares and can be mitigated by dietary supplementation. Sci Rep 14:7571. 2024. PMID: 38555310


51. Gonzalez K, Merlin AC, Roye E, Osidele A, Ju B, Lee Y, Chicco AJ, Chung E. Voluntary Wheel Running Reduces Cardiometabolic Risks in Female Offspring Exposed to Lifelong High-Fat, High-Sucrose Diet. Med Sci Sport Exerc; 2024. PMID: 38595204


52. LeBar K, Liu W, Chicco AJ, Wang Z, Role of the Microtubule Network in the Passive Anisotropic Viscoelasticity of Right Ventricle with Pulmonary Hypertension Progression Acta Biomaterialia 176:293-303, 2024. PMID: 38272197


53. Whitcomb LA, Cao X, Thomas D, Wiese C, Pessin AS, Zhang R, Wu JC, Weil MM, Chicco AJ. Mitochondrial reactive oxygen species impact human fibroblast responses to protracted gamma-ray exposures. Int J Radiat Biol 100(6):890-902, 2024. PMID: 38631047


54. Cheng M-H, Way R, Fresa KJ, Catandi GD, Carnevale EM, Chicco AJ, Chen TW. IMSIS: An Instrumented Microphysiological System with Integrated Sensors for Monitoring Cellular Metabolic Activities; IEEE Transactions on Biomedical Circuits and System, 2024.

1. Cao X, Thomas D, Whitcomb L, Wang M, Chatterjee A, Chicco AJ, Weil MM, Wu JC. Modeling Radiation-induced Cardiovascular Dysfunction with Human iPSC-Derived Engineered Heart Tissues J Mol Cell Cardiol 188:105-107, 2024. PMID: 38431383

56. Greyslak KT, Hetrick B, Bergman BC, Dean TA, Wesolowski SR, Gannon M, Schenk S, Sullivan EL, Aagaard KM, Kievit P, Chicco AJ, Friedman JE, McCurdy CE. A Maternal Western-Style Diet Impairs Skeletal Muscle Lipid Metabolism in Adolescent Japanese Macaques. Diabetes. 2023 Dec 1;72(12):1766-1780. PMID: 37725952


57. Barton CK, Hassel DM, Anders K, Weir TL (2024) Is butyrate concentration in the equine gastrointestinal tract altered during and after surgery for treatment of large colon obstruction? Animals 14: 3203; IF: 3.0


58. Lustiv T, Neil ES, McGinley JN, Didinger C, Fitzgerald VK, Weir TL, Hussan H, Hartman TJ, Thompson HJ (2024) Impact of a Pulse-Enriched Human Cuisine on Functional Attributes of the Gut Microbiome Using a Preclinical Model of Dietary-Induced Chronic Diseases. Nutrients 16: 3178. https://doi.org/10.3390/nu16183178; IF: 5.2


59. Wilson JW, Thompson TW, Wei Y, Chaparro J, Stull VJ, Nair MN, Weir TL (2024) Comparison of the In Vitro Iron Bioavailability of Tempeh Made with Tenebrio molitor to Beef and Plant-Based Meat Alternatives. Nutrients 16, 2756; IF: 5.2


60. Risk BD, Graham EL, Zhang M, Wei Y, Stark G, Brown G, Gentile CL, Weir TL (2024) Bacillus subtilis probiotic partially reverses endothelial dysfunction in high fat -diet fed mice. Beneficial Microbes. DOI: 10.1163/18762891-bja00052. IF: 5.4


61. Vita AA, Roberts K, Gunderson A, McClure R, Farris Y, Danzck R, Zwickey H, Bradley R, Weir TL (2024) Exploring relationships between habitual polyphenol consumption and gut microbiota in the INCLD Health cohort. Nutrients 16(6): 773. IF:5.2


62. Williams NB, Weir TL (2024) Spore-Based Probiotic Bacillus subtilis: Current Applications in Humans and Future Perspectives. Fermentation 10:2, 78. IF: 5.123


63. Sly B, Weir TL, Cunningham-Sabo L, Leisz S, Stull VJ, Melby CL (2023) Increasing household diet diversity and food security in rural Rwanda using small-scale nutrition- sensitive agriculture: A community-level study. Nutrients 15, 3137; https://doi.org/10.3390/nu15143137 IF:5.2


64. Ecton KE, Graham EL, Risk BD, Brown GD, Stark GC, Wei Y, Trikha SRJ, Weir TL, Gentile CL (2023) Toll-like receptor 4 deletion partially protects mice from high fat diet-induced arterial stiffness despite perturbation to the gut microbiota. Microbiomes 2:1095997.


65. Ventura M, Holland ME, Bartlett-Smith M, Chaparro JM, Prenni JE, Patz JA, Paskewitz A, Weir TL, Stull VJ (2023) Suitability of maize crop residue fermented by Pleurotus ostreatus as feed for edible crickets: growth performance, micronutrient content, and iron bioavailability. Front Nutr.3389/fnut.2023.1157811 IF: 5


66. Kopparapu PR, Pearce MC, Löhr CV, Duong C, Jang HS, Tyavanagimatt S, O'Donnell EF 3rd, Nakshatri H, Kolluri SK. Identification and Characterization of a Small Molecule Bcl-2 Functional Converter. Cancer Res Commun. 2024 Mar 4;4(3):634-644. PMID: 38329389.


67. Kopparapu PR, Löhr CV, Pearce MC, Tyavanagimatt S, Nakshatri H, Kolluri SK. Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2) Suppresses Breast Cancer Lung Metastasis. ACS Pharmacol Transl Sci. 2024 May 1;7(5):1302-1309. PMID: 38751629.


68. Elson DJ, Nguyen BD, Korjeff NA, Wilferd SF, Puig-Sanvicens V, Sang Jang H, Bernales S, Chakravarty S, Belmar S, Ureta G, Finlay D, Plaisier CL, Kolluri SK. Suppression of Ah Receptor (AhR) increases the aggressiveness of TNBC cells and 11-Cl-BBQ-activated AhR inhibits their growth. Biochem Pharmacol. 2023 215:115706. PMID: 37506922.


69. Upadhyaya B^, Moreau R, Majumder K* (2024). Antioxidant and Anti-Inflammatory Capacities of Three Dry Bean Varieties after Cooking and In Vitro Gastrointestinal Digestion. Journal of Agricultural and Food Chemistry, doi: 10.1021/acs.jafc.4c02215


70. Jayakody L, Hamilton-Brehm S, Anderson K, McCarroll M, Aruma Baduge G, Sivakumar P, Majumder K, Jasiulk I, Tannenbaum R (2024). Next-generation 3D-printed nutritious food derived from waste plastic and biomass. Trends in Biotechnology. 42 (8), 799. doi: 10.1016/j.tibtech.2024.04.004


71. Motta‐Romero H, Guha S^, Seravalli J, Majumder K, Rose D (2024). The effect of food processing on the bioaccessibility of cadmium and micronutrients from whole wheat porridge. Cereal Chemistry, 101 (4), 759. doi: 10.1002/cche.10778


72. Behounek M, Cochran D, Motta‐Romero H, Yang Q, Ding W, Morton M, Majumder K, Powers R, Rose D (2024). In Vitro Fermentation of Animal and Plant Protein Isolates by the Human Gut Microbiota Under High and Low Carbohydrate Conditions. Molecular Nutrition & Food Research, 68, 230555. doi: 10.1002/mnfr.202300555


73. Nolasco E^, Baraka E^, Yang J, Ciftci N. O, Majumder K* (2024). In-vitro bio-accessibility and antioxidant activity of commercial standard and enriched whole egg compounds influenced by production and domestic cooking practices. Food Chemistry, 430, 136948. doi: 10.1016/j.foodchem.2023.136948


74. Guha S^, Majumder K* (2024). Efficacy of Great Northern beans-derived bioactive compounds in reducing vascular inflammation. Food Bioscience, 57, 103524. doi: 10.1016/j.fbio.2023.103524


75. Mantzios M, Timko A, Bello NT, Rodriguez D, Micioni Di Bonaventura MV. Editorial: Reviews in eating behavior: navigating complexities in health interventions, dietary practices and adolescence. Front Psychol. 2024 Sep 17;15:1477863. doi: 10.3389/fpsyg.2024.1477863. PMID: 39355291; PMCID: PMC11442386.


76. Agkun E, Uzumcu M, Bello NT. Central nervous system stimulants and drugs that suppress appetite. In S. D. Ray (Ed.), Side effects of drugs annual Vol. 46 (pp. 547-561). 2024. doi.org/10.1016/bs.seda.2024.09.003.


77. Fields SE, Shah H, Elango E, Akgun E, Bernstein E, Simon JE, Bello NT. Kratom (Mitragyna speciosa) alkaloids effect on hemodynamic and pulmonary measures in normal weight and obese mice.The Obesity Society Annual Meeting, November 4, 2024 & Pioneers in Endocrinology, 2024

01/09/2026

There were 90 new publications by W5122 members in 2024-2025 period, addressing the effects of bioactive nutrients on health and chronic disease risk, basic insights into nutrient metabolism, and the development of new methodology and technologies for studying these processes in humans and model systems.  Publications are listed below with W5122 group members in boldfaced text.

1. Zhang J, Yao D, Shurson GC, Chen C. Chemometric Characterization of Whole Stillage and Distillers Dried Grains with Solubles from Industrial Bioethanol Production Reveals the Impacts of Processing on Fermentation Metabolites. J Agric Food Chem. 73, 28262 (2025) DOI: 1021/acs.jafc.5c08081


2. Yin R, Sargsyan D, Wu R, Hudlikar R, Li S, Kuo HC, Sarwar MS, Zhou Y, Gao Z, Howell A, Chen C, Blaser MJ, Kong AN. Microbiome and Metabolome Alterations in Nrf2 Knockout Mice with Induced Gut Inflammation and Fed with Phenethyl Isothiocyanate and Cranberry Enriched Diets. Molecular Nutrition & Food Research e70283 (2025) https://doi.org/10.1002/mnfr.70283


3. Steffen BT, Lusczek ER, Jacobs Jr DR, Chen C, Murthy VL, Van Horn L, Terry JG, Carr JJ, Steffen LM. No Evidence of Metabolomic Disruptions From Real-World Intakes of Aspartame or Saccharin: The Coronary Artery Risk Development in Young Adults Study. J Diabetes 8, e70138 (2025) https://doi.org/10.1111/1753-0407.70138


4. Ding F, Weber WJ, Su R, Crooker BA, Chen C. Effect of Holstein Genotype and Energy Balance on Lipids, Carnitine and Short-Chain Carboxylic Acids in Milk During Early Lactation. Lipidology 2, 6 (2025) https://doi.org/10.3390/lipidology2010006


5. Mosher W, Yao D, McGhee M, Giesting DW, Faris RJ, Chen C. Differential Dispositions of Deoxynivalenol in Nursery and Finishing Pigs under Sulfonation Treatment Revealed by Metabolomic Profiling. ACS Agricultural Science & Technology. 2025 https://doi.org/10.1021/acsagscitech.4c00677


6. Kerr BJ, Wilson VC, Zhang J, Chen C. Influence of feeding thermally peroxidized lipids on the performance of growing pigs. J Anim Sci, 103, skaf015 (2025) DOI: 1093/jas/skaf015


7. Boardman K, Sun X, Yao D, Chen C, van Lierop L, Hu B. Increasing the Nutritional Value of Camelina Meal via Trametes versicolor Solid-State Fermentation with Various Co-Substrates. Fermentation 11, 77 (2025) https://doi.org/10.3390/fermentation11020077


8. Guse K, Mao Q, Chen C, Gomez A. Meta-Omics Analyses of Conventional and Regenerative Fermented Vegetables: Is There an Impact on Health-Boosting Potential? Fermentation11, 22 (2025) https://doi.org/10.3390/fermentation11010022


9. Johnson AJ, Li W, Dittrich BI, Cole AC, Prodell MK, Lyons JW, Fritz SA, Fregulia P, Chen C, Kwon CH, Jang YD. Effect of second iron injection on growth performance, hematological parameters, and fecal microbiome of piglets fed different dietary iron levels. J Anim Sci, 103, skae371 (2025) https://doi.org/10.1093/jas/skae371


10. Whitcomb LA, Berry K, LaVergne SM, Natter N, Baxter BA, Rao S, Tipton M, Gritsenko MA, Weitz KK, Gerbasi V, Bramer L, Piehowski P, Webb TL, Henao-Tamayo M, Chicco AJ, Dunn J, Dutt TS, Ryan EP.  Blood pro-thrombotic analytes and platelet activation are associated with post-acute sequelae of COVID-19. BMC Infectous Dis, In press1186/s12879-025-11824-3


11. Dolan CC, Whitcomb LA, Del Carpio E, Rose L, Chicco AJ, Crans DC. How vanadium and manganese compounds impact cardiac mitochondrial function. Front Chem Biol DOI 10.3389/fchbi.2025.1602602


12. * Fresa KJ, Catandi GD, Gonzalez-Castro RA, Omar A, Whitcomb LA, Cheng M-H, Chen TW, Carnevale EM,Chicco AJ. Impact of dietary essential fatty acids on phospholipid composition and mitochondrial function in aged mares.  Sci Rep  15:43295, 2025.


13. Asma K Omar AK, Li Puma LC, Risk BD, Witt AC, Izon CS, Whitcomb LA, Kareng DJ, Winger QA, Bouma GJ, Chicco AJ. Validation of an ovine model for studying impacts of prenatal docosahexaenoic acid supplementation on fetal tissue membrane composition and metabolism. J Nutri Biochem Oct 4:110137. doi: 10.1016/j.jnutbio.2025.110137. PMID: 41052657


14. Mueller RL, Li Puma LC, Itgen MW, Chicco AJ. Evolutionary diversity of muscle OXPHOS efficiency across ectothermic vertebrates. R. Soc. B 292:20250374, 2025. /doi.org/10.1098/rspb.2025.0374


15. Nunes LGA, Weingrill RB, Fredrick SBJ, Lorca R, Lee M-J, Atif SM, Chicco AJ, Rosario FJ, Urschitz J. Trophoblast‐specific Deptor knockdown enhances trophoblast nutrient transport and fetal growth in mice. Acta Physiologica. 241:e70012, 2025. https://doi.org/10.1111/apha.70012


16. Zhu C, Whitcomb LA, Chicco AJ, Gravely ME, Alcocer HM, Alambarrio DA, Gonzalez JM,  Smith CL, Nair MN, Loh HY, Engle TE, Niraula A, Zhai C. Nicotinamide Riboside Supplementation Affects Postmortem Mitochondrial Functionality and Apoptotic Activation Metabolites15:31,2025; PMID: 39852374


17. Tait C, Chicco AJ, Naug D. Brain energy metabolism as an underlying basis of slow and fast cognitive phenotypes in honeybees J Exp Biol227 (17):247835, 2024. PMID: 39092671


18. Fresa KJ, Catandi GD, Whitcomb LA, Gonzalez-Castro RA, Chicco AJ, Carnevale EM. Adiposity in mares induces insulin dysregulation and mitochondrial dysfunction which can be mitigated by nutritional intervention.  Sci Rep14:13992, 2024. PMID: 38886475


19. Catandi GD, Fresa KJ, Cheng MH, Whitcomb LA, Broekling CD, Chen TW, Chicco AJ, Carnevale EM.  Follicular metabolic alterations are associated with obesity in mares and can be mitigated by dietary supplementation. Sci Rep 14:7571. 2024. PMID: 38555310


20. Gonzalez K, Merlin AC, Roye E, Osidele A, Ju B, Lee Y, Chicco AJ,Chung E. Voluntary Wheel Running Reduces Cardiometabolic Risks in Female Offspring Exposed to Lifelong High-Fat, High-Sucrose Diet. Med Sci Sport Exerc; 2024. PMID: 38595204


21. Kim, T., Palla, G., Raut, B., Verma, M.S., Ardekani, A. (Submitted: 24 September 2025) Evaluation of Paper-based Loop-Mediated Isothermal Amplification Submitted to Analytical Chemistry.


22. Kamel, M.K., Davidson, J.L., Dextre, A., Ault, A., Pillai, D., Koziol, J., Schoonmaker, J.P., Johnson, T.A., Verma, M.S.* (Submitted: 23 October 2025) Development and evaluation of novel quantitative PCR (qPCR) and loop-mediated isothermal amplification (LAMP) assays for bovine adenovirus type 7 Submitted to The Veterinary Journal.


23. Davidson, J.L., Maruthamuthu, M.K., Kamel, M., Mohan, S., Pascual-Garrigos, A., Dextre, A., Centeno-Delphia, R.E., Boerman, J.P., Pillai, D., Koziol, J., Ault, A., Schoonmaker, J.P., Johnson, T.A., Verma, M.S.* (Submitted: 29 July 2025) Detection of five viruses commonly implicated with Bovine Respiratory Disease using loop-mediated isothermal amplification Submitted to Veterinary Quarterly.


24. Athalye, S.M., Maruthamuthu, M.K., Esmaili, E., Boodaghidizaji, M., Raffaele, J., Selvamani, V., Smith, J.P., Matos, T., Rustandi, R., Ardekani, A., Verma, M.S.* (2026) Real-time monitoring of attenuated cytomegalovirus using Raman spectroscopy allows non-destructive characterization during flow Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 345, 126761, DOI: 10.1016/j.saa.2025.126761


25. Rafiq, N., Verma, M.S.* (2025) Design and development of a field-deployable water bath for loop-mediated isothermal amplification assay IEEE Sensors Journal. DOI: 10.1109/JSEN.2025.3588790


26. Ahmed, B., Raut, B., Pauley, A., Davidson, J.L., Yang, S., Verma, M.S.* (2025) Development of a Portable Paper-based Biosensor for the Identification of Genetically Modified Corn (Zea mays) and Soybean (Glycine max) Biosensors and Bioelectronics 287, 117690. DOI: 10.1016/j.bios.2025.117690


27. Kamel, M., Davidson, J.L., Schober, J.M., Fraley, G.S., Verma, M.S.* (2025) A paper-based loop-mediated isothermal amplification assay for highly pathogenic avian influenza Scientific Reports 15, 12110. DOI: 10.1038/s41598-025-95452-6


28. Mayorga, C., Athalye, S.M., Boodaghidizaji, M., Sarathy, N., Hosseini, M., Ardekani, A., Verma, M.S.* (2025) Limit of detection of Raman spectroscopy using polystyrene particles from 25 to 1000 nm in aqueous suspensions ACS Analytical Chemistry 97, 16, 8908–8914. DOI: 10.1021/acs.analchem.5c00182


29. Kaur, S., Bran, L., Rudakov, G., Wang, J., Verma, M.S.* (2025) Propidium monoazide is unreliable for quantitative live-dead molecular assays ACS Analytical Chemistry 97, 5, 2914-2921. DOI: 10.1021/acs.analchem.4c05593


30. Wickware, C., Ellis, A.C., Verma, M.S., Johnson, T.A.* (2025) Phenotypic antibiotic resistance prediction using antibiotic resistance genes and machine learning models in Mannheimia haemolytica Veterinary Microbiology 302: 110372 DOI: 10.1016/j.vetmic.2025.110372


31. Ranjbaran, M., Kaur, S., Wang, J., Raut, B., Verma, M.S.* (2024) A drop dispenser for simplifying on-farm detection of foodborne pathogens. PLoS One 19(12): e0315444. DOI: 10.1371/journal.pone.0315444


32. Kevin Whelan, Margaret Alexander, Claire Gaiani, Genelle Lunken, Andrew Holmes, Heidi M Staudacher, Stephan Theis, Maria L Marco. 2024. Design and reporting of prebiotic and probiotic clinical trials in the context of diet and the gut microbiome. Nature Microbiology. 9(11):2785-2794. https://doi.org/10.1038/s41564-024-01831-6


33. Aviaja Hauptmann, Stephany Maroney, Jessica Bissett Perea, Maria L Marco. 2025. Growing microbiology literacy through interdisciplinary and Indigenous human rights frameworks. Journal Microbiology and Biology Education. 26(1):e0015224 https://doi.org/10.1128/jmbe.00152-24


34. Lei Wei, Wannes Van Beeck, Melanie Hanlon, Erin DiCaprio, Maria L Marco. 2025. Lacto-fermented fruits and vegetables: bioactive components and effects on human health. Annual Review of Food Science and Technology. 16(1):289-314 1146/annurev-food-052924-070656


35. Clarissa Santos Rocha, Katie L Alexander, Carolina Herrera, Mariana G Weber, Irina Grishina, Lauren A Hirao, Dylan J Kramer, Juan Arredondo, Abigail Mende, Katti R Crakes, Anne N Fenton, Maria L Marco, David A Mills, John C Kappes, Lesley E Smythies, Paul Ziprin, Sumathi Sankaran-Walters, Phillip D Smith, and Satya Dandekar. 2025. Microbial remodeling of gut tryptophan metabolism and indole-3-lactate production regulate epithelial barrier repair and viral suppression in human and simian immunodeficiency virus infections. Mucosal Immunology. S1933-0219(25)00011-X. doi: 10.1016/j.mucimm.2025.01.011


36. Lei Wei and Maria L Marco. 2025. The fermented cabbage metabolome and its protection against cytokine-induced intestinal barrier disruption of Caco-2 monolayers. Applied Environmental Microbiology 91(5):e0223424. https://doi.org/10.1128/aem.02234-24


37. Alejandra Mejía-Caballero and Maria L Marco. 2025. Lactobacilli biology, applications and host interactions. Nature Reviews Microbiology. https://doi.org/10.1038/s41579-025-01205-7


38. Glory Bui and Maria L Marco. 2025. Impact of fermented dairy on gastrointestinal health and associated biomarkers. Nutrition Reviews. Jul 24:nuaf114. doi: 10.1093/nutrit/nuaf114


39. Supatirada Wongchanla, Kunal Dixit, Sangwoo Park, Kwangwook Kim, Shuhan Sun, Maria L Marco, Steven B. Palomares, Alejandra Mejia‑Caballero, Sahana Mohan, Xunde Li, Xiaojing Li,  and Yanhong Liu. 2025. Effects of dietary L‑glutamate and L‑aspartate supplementation on growth performance, severity of diarrhea, intestinal barrier integrity, and fecal microbiota of weaned piglets challenged with F18 enterotoxigenic Escherichia coli. Journal of Animal Science and Biotechnology. 16:131 https://doi.org/10.1186/s40104-025-01266-x


40. Valdez R, Chang Y, Pennington JM, Tilton SC. 2025. MicroRNA mediated changes in susceptibility for benzo[a]pyrene toxicity in a 3D respiratory model for asthma. Accepted to Current Res. Toxicol.


41. Burns K, Biggerstaff A, Pennington JM, Anderson KA, Tilton SC. 2025. Co-culture of primary human bronchial epithelial cells at the air-liquid interface and THP-1 macrophages to investigate the toxicity of polycyclic aromatic hydrocarbons. Toxics, Special Issue “Emerging Pollutants in the Air and Health Risks”.  13(12), 1065; doi.org/10.3390/toxics13121065. PMCID: PMC12737494.


42. Colvin V, Bastin K, Siddens LK, Maier ML, Williams DE, Smith JN, Tilton SC. 2025. Building a Predictive Model for PAH Dosimetry in ALI-HBECs using Benzo[a]pyrene. Reports. 15:102133. doi.org/10.1016/j.toxrep.2025.102133. PMCID: PMC12517105.


43. Colvin V, Owiti NA, Engelward BP, Tilton SC. Utilization of the CometChip Utilization of the CometChip Assay for Detecting PAH-induced DNA Bulky Adducts in a 3D Primary Human Bronchial Epithelial Cell Model.  Toxicology. 517:154241. doi: 10.1016/j.tox.2025.154241. PMCID: PMC12356187.


44. Valdez R, Rivera BN, Chang Y, Pennington JM, Fischer KA, Lohr CV, Tilton SC. 2024. Assessing susceptibility for polycyclic aromatic hydrocarbon toxicity in an in vitro 3D respiratory model for asthma. Frontiers in Toxicology, Special Issue “Linking Environmental Exposure to Toxicants and Chronic Disease”. 6:1287863. doi.org/10.3389/ftox.2024.1287863. PMCID:


45. Colvin V, Bramer LM, Rivera BN, Pennington JM, Waters KM, Tilton SC. 2024. Modeling PAH mixture interactions in a human in vitro organotypic respiratory model. J. Mol. Sci. 25(8), 4326. doi.org/10.3390/ijms25084326. PMCID: PMC11050152.


46. Samy MN, Attia EZ, Khalifa BA, Darwish AG, Al-Karmalawy AA, Alnajjar R, Abdelmohsen UR, Ibrahim MA, Ross SA. Undescribed cytotoxic butenolides; asperterreunolides A-E, isolated from endophytic fungus Aspergillus terreus derived from Artemisia arborescens, supported with in silico study. Phytochemistry (2025).


47. Darwish AG, Das PR, Olaoye E, Gajjar P, Ismail A, Mohamed AG, Tsolova V, Hassan NA, El Kayal W, Walters KJ, El-Sharkawy I. Untargeted flower volatilome profiling highlights differential pollinator attraction strategies in muscadine. Front Plant Sci (2025).


48. Ismail A, Gajjar P, Darwish AG, Abuslima E, Islam T, Mohamed AG, Tsolova V, Nick P, El Kayal W, El-Sharkawy I. Redox and osmotic homeostasis: Central drivers of drought resilience in grapevine rootstocks. Plant Physiol Biochem (2025).


49. Ibrahem ES, Fahim JR, Samy MN, Darwish AG, Desoukey SY, Kamel MS, Ross SA. Chemical and Biological Investigation of Ceiba chodatii Flowers. Chemistry (2025).


50. Samy MN, Kemelbek M, Alshymaa AG, Darwish AG, Gauhar S, Samir AR. Isolation and chemical characterization of secondary metabolites from Gazania rigens and their antimicrobial and cytotoxic activities. Natural Product Research (2024).


51. O'Brien, C.E., Frese, S. (co-first)., Cernioglo, K., DamiaN-Medina, K., Mitchell, R.D., Casaburi, G., Melnyk, R.A., Henrick, B.M., Smilowitz, J.T. (2025). “Randomized, Placebo-Controlled Trial Reveals the Impact of Dose and Timing of Bifidobacterium infantis Probiotic Supplementation on Breastfed Infants’ Gut Microbiome.” https://doi.org/10.1128/msphere.00518-25


52. Yalçıntaş, Y.M., and Matthew J. Bolino, Duman, H, Sarıtaş, S., Pekdemir, B., Kalkan, A.E., Canbolat, A.A., Bolat, E., Eker, F., Rocha, J.M., Frese S.A.* & Sercan Karav (2025): Prebiotics: types, selectivity and utilization by gut microbes, International Journal of Food Sciences and Nutrition, https://doi.org/10.1080/09637486.2025.2582557.


53. Bolino, M., Duman, H., Avcı, İ., Kayili, H.M., Petereit, J., Salih, B., Karav, S. and Frese, S.* (2025) ‘Proteomic and N-glycomic comparison of synthetic and bovine whey proteins’, Microbiology Spectrum. https://doi.org/10.1128/spectrum.00200-25


54. Tatarko, A.R., Vannette, R., Frese, S. and Leonard, A.S. (2025). ‘A wild bumble bee shows intraspecific differences in sensitivity to multiple pesticides’, Royal Society Open Science. https://doi.org/10.1098/rsos.250281


55. Bolino, M., Haththotuwe Gamage, N., Duman, H., Abiodun, O., De Mello, A.S., Karav, S. and Frese, S.* (2025) ‘Novel Endo-β-N-Acetylglucosaminidases Derived from Human Fecal Samples Selectively Release N-Glycans from Model Glycoproteins’, Foods, 14(8), p.1288. https://doi.org/10.3390/foods14081288


56. Bolino, M., Avci, I., Kayili, H.M., Duman, H., Salih, B., Karav, S. and Frese, S.* (2025) ‘Identification and comparison of N-glycome profiles from common dietary protein ingredients’, Food Chemistry: X. https://doi.org/10.1016/j.fochx.2024.102025


57. Alipour, Z., Duman, H., Lee, J., Karav, S., & Frese, S. (2025). The microbiome in infant gut health and development. In Nutrition in the Control of Inflammation (pp. 29-49). Academic Press. https://doi.org/10.1016/B978-0-443-18979-1.00003-4


58. Lucey CM, Pearson BL, DeSantis K, GoldsmithJ, Halliday AN, Navas-Acien A, Schilling K, Basu  Isotopic fractionation of natural uranium in mice as a potential biomarker of renal accumulation (2025). Environmental Science & Technology 59, 28: 14279–14289.


59. Andrade-Feraud CM, Acanda de la Rocha AM, Berlow NE, Duque S, Holcomb B, Coats ER, Ghurani YR, Lucey CM, Pearson BL, Guilarte TR, Azzam DJ. (2025) Chronic arsenic exposure of ovarian surface and fallopian tube cultures induces giant and/or multinucleated cells with phagocytosis-like properties and an inflammatory phenotype. Toxicology and Applied Pharmacology500: 117394.


60. Xie K, Scifo E, Pearson B, Ryan D, Henzel K, Markert A, Schaaf K, Wang C, Mi X, Tian X, Bonn S, Schölling M, Möhl CO, Bano D, Zhou Y, Ehninger D. (2025). Intermittent fasting boosts sexual behavior by limiting the central availability of tryptophan and serotonin. Cell Metabolism37(5): 1189-1205.e7


61. Briana M. Nosal, Alexander Aksenov, Catherine Andersen, Elaine Choung-Hee Lee, Yanjiao Zhou, Ock K. Chun. The gut-bone axis: Potential influence of anthocyanins and implications for postmenopausal osteoporosis. Food Science and Biotechnology. (In press; Accepted on May 5, 2025). https://doi.org/10.1007/s10068-025-01907-x


62. Manije Darooghegi Mofrad, Seoeun Ahn, Ock K. Chun. The Interplay of Diet, Genome, Metabolome, and Gut Microbiome in Cardiovascular Disease and Mortality: A Narrative Review. Curr Med Chem 2025 Jan 6.  https://doi.org/10.2174/0109298673342364241119114722.


63. Alam MN, Marney L, Yang L, Choi J, Cerruti N, Techen N, Bassett S, Smith J, Brown K, Cabey K, Viswanathan R, Rajagopal S, Soumyanath A, Stevens JF, Maier CS. Clustering of chemical profiles of Centella asiatica cultivars, grown in greenhouses, allows grouping of metabolites with similar production trends. Ind Crops Prod. 2025 Sep 1;231:121159. doi: 10.1016/j.indcrop.2025.121159. Epub 2025 May 10. PMID: 40838195


64. Houriet J, Manwill PK, Magaña AA, Anderson VM, Beniddir MA, Bertrand S, Choi J, Clark TN, Foster LJ, Halabalaki M, Jarmusch AK, de Jonge NF, Khadilkar A, MacMillan JB, Maier CS, Marney LC, Marti G, Mikropoulou EV, Olivier-Jimenez D, Perez A, van der Hooft JJJ, Zdouc MM, Linington RG, Cech NB. Multilaboratory Untargeted Mass Spectrometry Metabolomics Collaboration to Identify Bottlenecks and Comprehensively Annotate A Single Dataset. Anal Chem. 2025 Aug 5;97(30):16110-16122. doi: 10.1021/acs.analchem.4c05577. Epub 2025 Jul 22. PMID: 40693864


65. Lin LW, Jang HS, Song Z, Ebrahimi A, Yang J, Nguyen BD, O'Donnell EF, Hendrix DA, Maier CS, Kolluri SK. Suppression of global protein synthesis and hepatocellular carcinoma cell growth by Benzimidazoisoquinoline, 4,11-Dichloro-BBQ. Biochem Pharmacol. 2025 Jun;236:116896. doi: 10.1016/j.bcp.2025.116896. Epub 2025 Mar 27. PMID: 40157458


66. Paraiso IL, Alcázar Magaña A, Alexiev A, Sharpton TJ, Maier CS, Kioussi C, Stevens JF. Reversing metabolic dysregulation in farnesoid X receptor knockout mice via gut microbiota modulation. PLoS One. 2025 Sep 5;20(9):e0331040. doi: 10.1371/journal.pone.0331040. eCollection 2025. PMID: 40911549 Free PMC article.     


67. Hack W, Kuhnau L, Martinez J, Marney LC, Choi J, Sohal AR, Koike S, Nguyen T, Maier CS, Soumyanath A, Gray NE. Triterpene and Caffeoylquinic Acid Constituents Contribute to the Cognitive-Enhancing, but Not Anxiolytic, Effects of a Water Extract of Centella asiatica in Aged Mice. Nutrients. 2025 Oct 8;17(19):3171. doi: 10.3390/nu17193171. PMID: 41097248 Free PMC article.     


68. Jamieson PE, Reichart NJ, Maier CS, Sharpton TJ, Bradley R, Metz TO, Stevens JF. Xanthohumol Alters Gut Microbiota Metabolism and Bile Acid Dynamics in Gastrointestinal Simulation Models of Eubiotic and Dysbiotic States. Int J Mol Sci. 2025 Nov 3;26(21):10698. doi: 10.3390/ijms262110698. PMID: 41226734


69. McDonald KL, Raichura Z, Pondugula SR, Marney L, Yang L, Choi J, Salamat JM, Brandes MS, Neff C, Adams K, Farmer G, Dennis C, Maier CS, Soumyanath A, Arnold RD, Calderón AI. Ashwagandha (Withania somnifera) Plant Extracts Affect the Cytochrome P450 System and Cytotoxicity of Primary Human Hepatocytes. J Diet Suppl. 2025;22(4):613-639. doi: 10.1080/19390211.2025.2514458. Epub 2025 Jun 24. PMID: 40551718; PMCID: PMC12266684.


70. Neiheisel S, Uchenik D, Marney L, Maier CS, Gray NE, Soumyanath A, Rakotondraibe HL. Development of a Proton Spin Network Fingerprint Library to Support Mass Spectrometry-Based Identification of Pharmacophore-Bearing Constituents in the Botanical Supplement Centella asiatica. J Nat Prod. 2025 Apr 25;88(4):975-984. doi: 10.1021/acs.jnatprod.4c01486. Epub 2025 Mar 28. PMID: 40152679; PMCID: PMC12060121.


71. Truong L, Bieberich AA, Fatig RO, 3rd, Rajwa B, Simonich MT, Tanguay RL. Accelerating antiviral drug discovery: early hazard detection with a dual zebrafish and cell culture screen of a 403 compound library. Arch Toxicol. 2025;99(3):1029-41. Epub 2024/12/28. doi: 10.1007/s00204-024-03948-3. PubMed PMID: 39730949; PMCID: PMC11821682.


72. Tanguay RL. The indispensable role of zebrafish as a new approach methodology (NAM) in toxicology. Toxicol Sci. 2025. Epub 2025/09/01 20:44. doi: 10.1093/toxsci/kfaf121. PubMed PMID: 40889284.


73. St Mary L, McClure R, Truong L, Carrell SJ, Waters KM, Tanguay RL. Phenotypically anchored transcriptomics across diverse agrichemicals reveals conserved pathways and unique gene expression signatures in zebrafish. Frontiers in Toxicology. 2025;7:1675060. Epub 2025/11/03. doi: 10.3389/ftox.2025.1675060. PubMed PMID: 41181350; PMCID: PMC12575134.


74. Rude CI, Smith JN, Scott RP, Schultz KJ, Anderson KA, Tanguay RL. A mixture parameterized biologically based dosimetry model to predict body burdens of polycyclic aromatic hydrocarbons in developmental zebrafish toxicity assays. Toxicol Sci. 2025;205(2):326-43. Epub 2025/03/21. doi: 10.1093/toxsci/kfaf039. PubMed PMID: 40117221; PMCID: PMC12118961.


75. Perone DM, Annalora AJ, Goldstone JV, Dickey AN, Salanga MC, Francolini RD, Wright FA, Marcus CB, Tanguay RL, Garcia-Jaramillo M. Zebrafish Cyp1b1 knockout alters eye and brain metabolomic profiles, affecting ocular and neurobehavioral function. Toxicol Appl Pharmacol. 2025;496:117246. Epub 2025/02/01 20:42. doi: 10.1016/j.taap.2025.117246. PubMed PMID: 39890032; PMCID: PMC12083501.


76. Morshead ML, Truong L, Tanguay RL. Position-Specific Methyl Substitution on Benzo[a]pyrene Drives AHR-Dependent Fin Duplication in Zebrafish. Toxicol Sci. 2025. Epub 2025/11/20. doi: 10.1093/toxsci/kfaf164. PubMed PMID: 41264521.


77. Morshead ML, Truong L, Simonich MT, Moran JE, Anderson KA, Tanguay RL. Developmental toxicity of alkylated PAHs and substituted phenanthrenes: Structural nuances drive diverse toxicity and AHR activation. Chemosphere. 2025;370:143894. Epub 2024/12/07. doi: 10.1016/j.chemosphere.2024.143894. PubMed PMID: 39643011; PMCID: PMC11732715.


78. Morshead ML, Truong L, Carrell SJ, Scott R, Anderson KA, Tanguay RL. Chemical structure drives developmental toxicity of alkyl-substituted naphthalenes in zebrafish. Environ Int. 2025;204:109837. Epub 2025/10/06. doi: 10.1016/j.envint.2025.109837. PubMed PMID: 41046622; PMCID: PMC12560828.


79. Morshead ML, Tanguay RL. Advancements in the Developmental Zebrafish Model for Predictive Human Toxicology. Curr Opin Toxicol. 2025;41. Epub 2025/02/03. doi: 10.1016/j.cotox.2024.100516. PubMed PMID: 39897714; PMCID: PMC11780918.


80. Lessard JM, Pyle D, Bowen J, Lin LW, E NM, Gladysiak A, Truong L, Kolluri SK, Tanguay RL, Wyatt CR, Stylianou KC. Aqueous-stable Mn(II)-MOF nanoparticles with high r(1) relaxivity and biocompatibility: a novel T(1) MRI contrast agent. J Mater Chem B. 2025. Epub 2025/11/06. doi: 10.1039/d5tb01711d. PubMed PMID: 41195545.


81. Konrad KS, Allen-Moyer K, Ellis L, Hessel E, Jaka O, Muriana A, Martinez BM, Del Pozo A, Schiavone V, Di Donato V, Sanz CM, Truong L, Tanguay R, Shockley KR, Ryan K, Hsieh JH. Power Calculations for Larval Zebrafish in Light-Dark Transition Test for Developmental Neurotoxicity. Neurotoxicology. 2025:103371. Epub 2025/12/26. doi: 10.1016/j.neuro.2025.103371. PubMed PMID: 41448279.


82. Kim J, Clark K, Barton C, Tanguay R, Moulton H. A Novel Zebrafish Model for Assessing In Vivo Delivery of Morpholino Oligomers. Methods Mol Biol. 2025;2964:263-76. Epub 2025/07/28. doi: 10.1007/978-1-0716-4730-1_17. PubMed PMID: 40720024.


83. Jamison J, Doman TJJ, Antenucci Z, Efromson J, Johnson C, Simonich MT, Harfouche M, Truong L, Tanguay RL. Enhanced high-throughput embryonic photomotor response assays in zebrafish using a multi-camera array microscope. SLAS Technol. 2025;33:100310. Epub 2025/05/31. doi: 10.1016/j.slast.2025.100310. PubMed PMID: 40446963; PMCID: PMC12338983.


84. Diemar MG, Giusti A, Michel-Caillet C, Leme DM, Wikoff D, Bloch D, Sass J, Beekmann K, Elliott KC, Tanguay R, Hofmaier T, Chiu W, Kienhuis A. How to organise a successful toxicology workshop? A participant perspective on the Collaboration to Harmonise the Assessment of Next Generation Evidence (CHANGE) workshop in Oslo, 18-20 June 2024. Arch Toxicol. 2025;99(7):3057-63. Epub 2025/05/15. doi: 10.1007/s00204-025-04064-6. PubMed PMID: 40372420.


85. Degnan DJ, Bramer LM, Truong L, Tanguay RL, Gosline SM, Waters KM. bmdrc: Python package for quantifying phenotypes from chemical exposures with benchmark dose modeling. PLoS Comput Biol. 2025;21(7):e1013337. Epub 2025/07/28. doi: 10.1371/journal.pcbi.1013337. PubMed PMID: 40720503; PMCID: PMC12313058.


86. Debad SJ, Aungst J, Carstens K, Ferrer M, Fitzpatrick S, Fritsche E, Geng Y, Hartung T, Hogberg HT, Li R, Mangas I, Marty S, Musser S, Perron M, Rattan S, Ruegg J, Sachana M, Schenke M, Shafer TJ, Smirnova L, Talpos J, Tanguay RL, Terron A, Bandele O. State of the science on assessing developmental neurotoxicity using new approach methods. ALTEX. 2025;42(1):121-44. Epub 2024/12/16. doi: 10.14573/altex.2410231. PubMed PMID: 39675048.


87. Jordan Hernandez, Shivdeep Hayer, Sophie Alvarez, Anne Fischer, Haley Hassenstab, Katherine Cooper, Zahraa Alsafwani, Andrew Benson, Mallory Van Haute, Jacques Izard, Hyun-Seob Song, and Jonathan Clayton. Microbiome and metabolome association network analysis identifies Clostridium_sensu_stricto_1 as a stronger keystone genus candidate than Bifidobacterium in the gut of common marmosets. mSystems (2025) e00214-‌25 [https://doi.org/10.1128/msystems.00214-25] [PMID: 40622159].


88. Grace McManaman, Josh J. Doolittle, and Jacques Izard. Decreased circulating hexanoic acid associated with Crohn’s disease and surgically altered digestive tracts in cross-sectional analysis. Gastroenterology (2025) 169 (1), S1623


89. Josh J. Doolittle, Jason R. Devlin, and Jacques Izard. Simplified index for assessing microbial diversity of the human digestive tract in a clinical setting. Gastroenterology (2025) 168 (3), S83


90. Stillwell, N.; Khadka, V.S.; Nerurkar, P.V. Impact of Natural Fermentation on Mineral Composition,Resistant and Non-Resistant Starches, Microbial Diversity, and Global Metabolite Profiles in Commercial Poi from Hawai‘i. Metabolites 2025, 15, 748. https://doi.org/10.3390/metabo15110748