07/16/2018

Peer-reviewed journal articles published in 2017 reporting research from this project

Hale, B.J., Hager, C.J., Siebert, J.T., Selsby, J.T., Baumgard, L.H., Keating, A.F., Ross, J.W. 2017. Heat stress induces autophagy in pig ovaries during follicular development. Biology of Reproduction. 97(3):426-437.

Kvidera, S.K., Horst, E.A., Sanz-Fernandez, M.V., Abuajamieh, M., Ganesan, S., Gorden, P.J., Green, H.B., Schoenberg, K.M., Trout, W.E., Keating, A.F., Baumgard, L.H. 2017. Characterizing effects of feed restriction and glucagon-like peptide 2 administration on biomarkers of inflammation and intestinal morphology. Journal of Dairy Science. 100(11):9402-9417.

Ganesan, S., Dickson, M.J., Keating, A.F. Pesticides. In: Encyclopedia of Reproduction. In Press.

Ross, J.W., Hale, B.J., Seibert, J.T., Romoser, M. R., Adur, M.K., Keating, A.F., Baumgard, L.H. 2017. Physiological mechanisms through which heat stress compromises reproduction in pigs. Molecular Reproduction and Development.  84(9): 934-945.

McNeel AK, Vallet JL, Snelling WM, Wright EC, Larimore EL, Amundson OL, Miles JR, Chase Jr CC, Lents CA, Sonstegard TE, Schroeder SG, Wood JR, Cupp AS, Perry GA, and Cushman RA (2017) Beef heifers with diminished numbers of antral follicles have decreased uterine protein concentrations, Anim Reprod Sci 179:1-9 PMID: 28215453

Romereim SM, Summers AF, Pohlmeier WE, Zhang P, Hou X, Talbott HA, Cushman RA, Wood JR, Davis JS, and Cupp AS (2017) Gene expression profiling of bovine ovarian follicular and luteal cells provides insight into cellular identities and functions, Mol Cell Endocrinol 439:379-394 PMID: 27693538

Romereim SM, Summers AF, Pohlmeier WE, Zhang P, Hou X, Talbott HA, Cushman RA, Wood JR, Davis JS, and Cupp AS (2017) Transcriptomes of bovine ovarian follicular and luteal cells, Data in Brief 10:335-339 PMID: 28004024

Talbott H, Hou X, Qiu F, Guda C, Yu F, Cushman RA, Wood JR, Wang C, Cupp AS, and Davis JS (2017) Early transcriptome responses of the bovine mid-cycle corpus luteum to prostaglandin F2 alpha includes cytokine signaling, Mol Cell Endocrinology 452: 93-109, PMID: 28549990

Talbott H, Hou X, Qiu F, Zhang P, Guda C, Yu F, Cushman RA, Wood JR, Wang C, Cupp AS, and Davis JS (2017) Transcriptomic and bioinformatics analysis of the early time-course of the response to prostaglandin F2 alpha in the bovine corpus luteum, Data in Brief 14:695-706, PMCID: PMC5596332

Wood JR and Cupp AS (2017) Female Endocrinology –Aromatization. Encyclopedia of Reproduction, Second Edition (accepted, in press)

Águila L, Felmer R, Arias ME, Navarrete F, Martin-Hidalgo D5, Lee HC, Visconti P, Fissore R. 2017. Defective sperm head decondensation undermines the success of ICSI in the bovine.  Reproduction. 154:207-218.

Cerny, K.L., R.A.C. Ribeiro, Q. Li, J.C. Matthews and P.J. Bridges.  2017.  Effect of lipopolysachharide (LPS) on the expression of inflammatory mRNAs and microRNAs in the mouse oviduct.  Reproduction, Fertility and Development.  doi: 10.1071/RD17241.

Li, Q., R. Hegge, P.J. Bridges and J. C. Matthews.  2017.  Pituitary genomic expression profiles of steers are altered by grazing of high vs. low endophyte-infected tall fescue forages.  PLoS One.  12(9): e0184612.

Willis, E.L., P.J. Bridges and J.E. Fortune.  2017.  Progesterone receptor and prostaglandins mediate LH-induced changes in messenger RNAs for ADAMTS proteases in theca cells of bovine periovulatory follicles.  Molecular Reproduction and Development.  84:55-66.

Miles, E.D., B.W. McBride, P.J. Bridges and J.C. Matthews.  2017.  Effect of 17β-estradiol administration on hepatic expression of glutamine synthetase, β-catenin, and GPR30 in aged beef cows.  Canadian Journal of Animal Science.  97:281-289.

Hester J, Hanna-Rose W and Diaz FJ.  2017. Zinc depletion reduces fertility and disrupts oocyte development in C. elegans.  Comparative Biochemistry and Physiology 191, 203-209.

Tian X, Anthony K and Diaz FJ.  2017. Transition metal chelator induces progesterone production in mouse cumulus-oocyte complexes and corpora lutea. Biological Trace Mineral Research. doi:10.1007/s12011-016-0841-x.

Krumm, C. S., S. L. Giesy, L. S. Caixeta, W. R. Butler, H. Sauerwein, J. W. Kim, and Y. R. Boisclair. Effect of hormonal and energy-related factors on plasma adiponectin in transition dairy cows. J Dairy Sci. 100 (11):9418-9427, 2017.

Cheong, S. H., O. G. Sa Filho, V. A. Absalón Medina, A. Schneider, W. R. Butler, and R. O. Gilbert. Uterine and systemic inflammation influences ovarian follicular function in postpartum dairy cows. PLoS One 12 (5):e0177356, 2017.

Jaskiewicz NJ, Parisi S, Hermawan C, Townson DH 2017 O-GlcNAcylation enhances the tumorigenic properties of cervical cancer cells in vitro. Clinical Obstetrics, Gynecology and Reproductive Medicine 3(3):1-6

Mattos FCSZ, Canavessi AMO, Wiltbank MC, Bastos MR, Lemes AP, Mourao GB, Susin I, Coutinho LL, Sartori R (2017). Investigation of mechanisms involved in regulation of progesterone catabolism using an overfed versus underfed ewe-lamb model. J Anim Sci  95:5537-46.

Barletta RV, Maturana M, Carvalho PD, Del Valle TA, Netto AS, Renno FP, Mingoti RD, Gandra JR, Mourao GB, Fricke PM, Sartori R, Madureira EH, Wiltbank MC (2017). Association of changes among body condition score during the transition period with NEFA and BHBA concentrations, milk production, fertility, and health of Holstein cows. Theriogenology 104:30-6.

Hackbart KS, Bender RW, Carvalho PD, Vieira LM, Dresch AR, Guenther JN, Gencoglu H, Nascimento AB, Shaver RD, Wiltbank MC (2017). Effects of propylene glycol or elevated luteinizing hormone during follicle development on ovulation, fertilization, and early embryo development. Biol Reprod  97:550-63.

Pereira MHC, Wiltbank MC, Guida TG, Lopes FR, Vasconcelos JLM (2017B). Comparison of 2 protocols to increase circulating progesterone concentration before timed artificial insemination in lactating dairy cows with or without elevated body temperature. J Dairy Sci  100:8455-70.

Garcia-Guerra A, Motta JCL, Melo LF, Kirkpatrick BW, Wiltbank MC (2017A). Ovulation rate, antral follicle count, and circulating anti-Mullerian hormone in Trio allele carriers, a novel high fecundity bovine genotype. Theriogenology  101:81-90.

Garcia-Guerra A, Kirkpatrick BW, Wiltbank MC (2017B). Follicular waves and hormonal profiles during the estrous cycle of carriers and non-carriers of the Trio allele, a major bovine gene for high ovulation and fecundity. Theriogenology  100:100-13.

Prata AB, Pontes GCS, Monteiro PLJ, Drum JN, Wiltbank MC, Sartori R (2017). Equine chorionic gonadotropin increases fertility of grazing dairy cows that receive fixed-time artificial insemination in the early but not later postpartum period. Theriogenology  98:36-40.

Mollo MR, Monteiro PLJ, Surjus RS, Martins AC, Ramos AF, Mourao GB, Carrijo LHD, Lopes G, Rumpf R, Wiltbank MC, Sartori R (2017). Embryo production in heifers with low or high dry matter intake submitted to superovulation. Theriogenology  92:30-5.

Pereira MHC, Sanches CP, Guida TG, Wiltbank MC, Vasconcelos JLM (2017A). Comparison of fertility following use of one versus two intravaginal progesterone inserts in dairy cows without a CL during a synchronization protocol before timed AI or timed embryo transfer. Theriogenology  89:72-8.

Baez GM, Trevisol E, Barletta RV, Cardoso BO, Ricci A, Guenther JN, Cummings NE, Wiltbank MC (2017). Proposal of a new model for CL regression or maintenance during pregnancy on the basis of timing of regression of contralateral, accessory CL in pregnant cows. Theriogenology  89:214-25.

Sartori R, Spies C, Wiltbank MC (2017). Effects of dry matter and energy intake on quality of oocytes and embryos in ruminants. Reprod Fertil Dev  29:58-65.

Ochoa JC, Penagaricano F, Baez GM, Melo LF, Motta JC, Guerra AG, Meidan R, Ferreira JCP, Sartori R, Wiltbank MC (2017). Mechanisms for rescue of CL during pregnancy: Gene expression in bovine CL following intrauterine pulses of Prostaglandins E1 and F2alpha. Biol Reprod DOI:10.1093/biolre/iox183.

Toledo MZ, Baez GM, Garcia-Guerra A, Lobos NE, Guenther JN, Trevisol E, Luchini D, Shaver RD, Wiltbank MC (2017). Effect of feeding rumen-protected methionine on productive and reproductive performance of dairy cows. PLoS ONE  12:e0189117.

Wijma, M. M. Pérez, M. Masello, D. G. García, M. L. Stangaferro, and J.O. Giordano. 2017. A resynchronization of ovulation program based on ovarian structures present at nonpregnancy diagnosis reduced time to pregnancy in lactating dairy cows. J. Dairy Sci. 101:1697-1707.

Wijma, M.L. Stangaferro, M. Masello, G. E. Granados, and J.O. Giordano. 2017. Resynchronization of ovulation protocols for dairy cows including or not including gonadotropin-releasing hormone to induce a new follicular wave: Effects on re-insemination pattern, ovarian responses, and pregnancy outcomes. J. Dairy Sci. 100:7613-7625.

S.H. Cheong, O.G. Sá Filho, V.A. Absalon-Medina, A. Schneider, W.R. Butler, R.O. Gilbert. Uterine and systemic inflammation influences ovarian follicular function in postpartum dairy cows. PLoS ONE. 2017 May 12(5):e0177356 doi:https://doi.org/10.1371/journal.pone.0177356. PMID: 28542500

Ealy, A.D. and Wooldridge, L.K. 2017. The evolution of interferon-tau. Reproduction 154:F1-F10.

Hughes, C.K., Xie, M.M., McCoski, S.R. and Ealy, A.D. 2017. Activities for leptin in bovine trophoblast cells. Dom. Anim. Endocrinol. 58:84-89.

Kelley, D.E., Galvao, K.N., Mortensen, C.J., Risco, C.A. and Ealy, A.D. 2017. Using Doppler ultrasonography on day 34 of pregnancy to predict pregnancy loss in lactating dairy cattle. J. Dairy Sci. 100:3266-3271.

Lu, Y., Bradley, J.S., McCoski, S.R., Gonzalez, J.M., Ealy, A.D. and Johnson, S.E. 2017. Reduced skeletal muscle fiber size following caloric restriction is associated with calpain-mediated proteolysis and attenuation of IGF-1 signaling. Am. J. Regul. Integr. Comp. Physiol. 312:R806-R815. 

Lugar, D.W., Rhoads, M.L., Clark-Deener, S.G., Callahan, S.R., Revercomb, A.K., Prusa, K.J. and Estienne, M.J. (2017). Immunological castration temporarily reduces testis size and function without long-term effects on libido and sperm quality in boars. Animal 11:643-649.

MacGhee, M.E., Bradley, J.S., McCoski, S.R., Reeg, A.M., Ealy, A.D. and Johnson, S.E. 2017.  Plane of nutrition affects growth rate, organ size and skeletal muscle satellite cell activity in newborn calves. J. Anim. Physiol. Anim. Nutr. 101:475-483.

Reinholt, B.M., Bradley, J.S., Jacobs, R.D., Ealy, A.D. and Johnson, S.E. 2017. Tissue organization alters gene expression in equine induced trophectoderm cells. Gen. Comp. Endocrinol. 247:174-182. 

Talbot, N.C., Sparks, W.O., Phillips, C., Ealy, A.D., Powell, A.M., Caperna, T.J., Garrett, W.M., Donavan, D.M. and Blomberg, L.A. 2017. Bovine trophectoderm cells induced from bovine fibroblasts with induced pluripotent stem cell reprogramming factors. Mol. Reprod. Dev. 84:468-485.

Wilson, M.L., McCoski, S.R., Geifer, A.J., Akers, R.M., Johnson, S.E. and Ealy, A.D. 2017. The influence of postnatal nutrition on reproductive tract and endometrial gland development in dairy calves. J. Dairy Sci. 100:3243-3256.

Xie, M., McCoski S.R., Johnson, S.E., Rhoads, M.L. and Ealy, A.D. 2017. Combinatorial effects of epidermal growth factor, fibroblast growth factor 2 and insulin-like growth factor 1 on trophoblast cell proliferation and embryogenesis in cattle. Reprod. Fertil. Dev. 29:419-430.

Zezeski, A.L., McCracken, V.L., Poole, R.K., Al Naib, A., Smith, J.K., McCann, M.A. and Rhoads ML. (2017) Metabolic and reproductive characteristics of replacement beef heifers subjected to an early weaning regimen involving high-concentrate feeding. Animal 11:820-825.

 

Conference papers and abstracts/presentations:

Yost, E.E., Arzuaga, X., Carlson, L., Keating, A.F., Lehmann, G. 2017. Focusing and refining the evaluation of reproductive endpoints in a systematic review of PCBs.  International Symposium on Systematic Review and Meta-Analysis of Laboratory Animal Studies.

Ganesan, S., Nteeba, J. and Keating, A.F.  2017. Impact of glyphosate on ovarian signaling pathways regulating folliculogenesis and steroidogenesis. Society for the Study of Reproduction annual meeting. 

Hines, E.A., Romoser, M., Keating, A.F., Baumgard, L.H., Niemi, J., Williams, N.H., Haberl, B., Kerr, B., Touchette, K.T., Ross, J.W. 2017. Supplementation of arginine does not improve gilt reproductive performance under commercial conditions. Society for the Study of Reproduction annual meeting. 

Hines, E.A., Romoser, M., Keating, A.F., Baumgard, L.H., Niemi, J., Haberl, B., Kerr, B., Touchette, K., Ross, J.W. 2017. Effect of maternal arginine supplementation on offspring performance of pigs in a commercial production environment.  Importance of nutrition and environment on birth weight, muscle growth, health and survival of the neonate workshop meeting.

Baumgard, L.H., Kvidera, S.K., Horst, E.A., Dickson, M.J., Ydstie, J.A., Shouse, C.S., Mayorga, E.J., Al-Qaisi, M., Lei, S., Bidne, K.L., Seibert, J.T., Hall, B.J., Keating, A.F., Ross, J.W., Selsby, J.T., Rhoads, R.P. 2017. Consequences of leaky gut on the immune system, metabolism, physiology and animal performance. American Society of Dairy Science annual meeting.

Dickson, M.J., Kvidera, S.K., Horst, E.A., Ydstie, J.A., Bidne, K.L., Wiley, C.E., Gunn, P.J., Keating, A.F., Baumgard, L.H. Chronic lipopolysaccharide infusion has no impact on dominant follicular size but affects 17β-estradiol in lactating dairy cows.  American Society of Dairy Science annual meeting.

Kvidera, S.K., Horst, E.A., Sanz Fernandez, M.V., Abuajamieh, M., Ganesa, S., Gordon, P.J., Green, H.B., Schoenberg, K.M., Trout, W.E., Keating, A.F., Baumgard, L.H. 2017. Glucagon-like peptide 2 administration improves biomarkers of inflammation and intestinal morphology in feed restricted lactating Holstein cows.  American Society of Dairy Science annual meeting.

Kvidera, S.K., Dickson, M.J., Horst, E.A., Ydstie, J.A., Shouse, C.S., Bidne, K.L., Mayorga, E.J., Al-Qaisi, M., Ramirez, H.A., Keating, A.F., Baumgard, L.H. 2017. Effects of continuous and increasing lipopolysaccharide infusion on basal metabolism in lactating cows.  American Society of Dairy Science annual meeting.

Dickson, M.J., Kvidera, S.K., Horst, E.A., Ydstie, J.A., Shouse, C.S., Mayorga, E.J., Al-Qaisi, M., Bidne, K.L., Ramirez, H.A., Keating, A.F., Baumgard, L.H. 2017. Metabolic responses to a glucose tolerance test and epinephrine challenge post-continuous lipopolysaccharide infusion in lactating cows.  American Society of Dairy Science annual meeting.

Dickson, M.J., Kvidera, S.K., Horst, E.A., Ydstie, J.A., Shouse, C.S., Mayorga, E.J., Al-Qaisi, M., Bidne, K.L., Ramirez, H.A., Keating, A.F., Baumgard, L.H. 2017. Chronic lipopolysaccharide infusion reduces productivity in lactating dairy cows.  American Society of Dairy Science annual meeting.

McCain AR, Beede KA, Yates DT, and Wood JR (2017) Maternal and Paternal Obesity Differentially Affect Fetal Growth with Maternal Obesity Associated Growth Restriction Attributed to Decreased 11-Hydroxysteroid Dehydrogenase Expression Society for the Study of Reproduction, Washington, DC

Timme KA, Xie F, Davis JS, and Wood JR (2017) Ovarian Inflammation and Oxidative Stress Associated with Diet Induced Obesity (DIO) Impacts RNA-Binding Protein Expression and Potentially mRNA Stability in the Murine Ovary and Oocyte.  Society for the Study of Reproduction, Washington, DC

Romereim SM, Summers AF, Pohlmeier WE, McFee RM, Spuri-Gomes R, Kurz SG, Davis JS, Wood JR, and Cupp AS (2017) A High-Androgen Microenvironment Inhibits Granulosa Cell Proliferation and May Alter Cell Identity. Society for the Study of Reproduction, Washington, DC

Abedal-Majed MA, Hart ML, Largen V, Magamage MPS, Kurz SG, Sargent KM, Bergman J, McFee RM, Cushman RA, Davis JS, Wood JR, and Cupp AS (2017) Ovarian Cortex from High A4 Cows Secrete Excess A4 and Exhibits Increased Oxidative Stress, Macrophage Markers and Arrested Follicle Development Which can be Partially Rescued by Angiogenic VEGFA Isoforms. Society for the Study of Reproduction, Washington, DC

Nafziger S, Abedal-Majed MA, Tenley S, Summers A, Hart ML, Harsh G, Bergman J, Kurz SG, Wood JR, Cushman RA, and Cupp AS (2017) Endocrine Profiles during Attainment of Puberty may Predict Reproductive Longevity in Heifers. Society for the Study of Reproduction, Washington, DC

Wood JR (2017) Maternal Obesity, the Gut Microbiota, and Oocyte mRNAs: Potential Impact on the Developing Embryo and Fetus. 4^th World Congress on Reproductive Biology, Naha, Okinawa, Japan (invited speaker)

McCain AR, Beede KA, Yates DT, Shankar K, and Wood JR (2017) Maternal Obesity Results in Fetal Growth Restriction Associated with Reduced Placental Efficiency and an Altered Placental Transcriptome. 14^th Annual Gilbert Greenwald Symposium on Reproduction, Kansas City, KS

Timme KA, Xie F, Davis JS, and Wood JR (2017) Ovarian Inflammation and Oxidative Stress Associated with Diet Induced Obesity (DIO) Impacts RNA-Binding Protein Expression and Potentially mRNA Stability in the Murine Ovary and Oocyte. 14^th Annual Gilbert Greenwald Symposium on Reproduction, Kansas City, KS

Nafziger S, Abedal-Majed MA, Tenley S, Summers AF, Hart ML, Harsh G, Bergman J, Kurz SG, Wood JR, Cushman RA, and Cupp AS (2017) Endocrine Profiles during Attainment of Puberty may Predict Reproductive Longevity in Heifers. 14^th Annual Gilbert Greenwald Symposium on Reproduction, Kansas City, KS

Abedal-Majed MA, Hart ML, Largen V, Magamage MPS, Kurz SG, Sargent KM, Bergman J, McFee RM, Cushman RA, Davis JS, Wood JR, and Cupp AS (2017) Ovarian Cortex from High A4 Cows Secrete Excess A4, and Exhibit Increased Oxidative Stress and Arrested Follicle Development which can be Partially Rescued by Angiogenic VEGFA Isoforms. 14^th Annual Gilbert Greenwald Symposium on Reproduction, Kansas City, KS

Wijma, M. Masello, M. L. Stangaferro, M. M. Pérez, and J. O. Giordano. 2017. A resynchronization of ovulation strategy based on the ovarian structures present at non-pregnancy diagnosis reduced time to pregnancy in lactating dairy cows. J. Dairy Sci. Volume 100, E-Supplement 2.

E.M. Sitko, S.H. Cheong 2017 Longitudinal study of metritis risk in dairy cattle. Clinical Theriogenology Sep; 9(3):432.

Ardestani G, Mehregan A, Carvacho I, He C, Fissore RA. Expression and Function of Cation Permeable Channels in Mouse GV oocytes. Gordon Research Conferences. July 2017- Fertilization and Activation of Development. New Hampshire. Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003.

Huang, P.J. Bridges and J.C. Matthews. 2017. Shifts in hepatic transcriptome profiles of growing versus finished beef steers. Journal of Animal Science 95 (Supplement 4) doi:10.2527/asasann.2017.326.

Huang, Y. Jia, Q. Li, W.R. Burris, P.J. Bridges and J.C. Matthews. 2017. GTRAP3-18 protein negatively modulates canalicular glutamate transport and glutamine synthesis capacity in the liver of finishing versus growing beef steers.  Journal of Animal Science 95 (Supplement 4) doi:10.2527/asasann.2017.327.

Li, P.J. Bridges and J.C. Matthews. 2017. Summer-long grazing of endophyte-infected tall fescue by growing beef steers inhibits expression of genes responsible for prolactin and ACTH synthesis. ASAS 2017 Southern Section Meeting. doi:10.2527/ssasas2017.058

Jia, Q. Li, G.E. Aiken, P.J. Bridges and J.C. Matthews. 2017. Effects of Selenium-form Phenotypes on Steers Grazing Endophyte-Infected Tall Fescue.  ASAS 2017 Southern Section Meeting. doi:10.2527/ssasas2017.057.

Fetter, ME, Pate, JL, Harvatine, KJ, Moats, J and Ott, TL. 2017. Effects of feeding an extruded flaxseed supplement on fatty acids in milk and plasma and immune function in transition dairy cows. Annual Meeting of the American Dairy Science Association, Pittsburg, PA.

Hughes CK and Pate JL. 2017. Differentially expressed proteins, transcripts, and miRNA in the corpus luteum during maternal recognition of pregnancy indicate matrix remodeling and miRNA regulation during luteal rescue. Proceedings of the 50^th annual meeting of the Society for the Study of Reproduction, Washington, DC.

Wetzel L, Inskeep EK and Pate JL. 2017. The importance of the luteal microenvironment for programming resident macrophages. Proceedings of the 50^th annual meeting of the Society for the Study of Reproduction, Washington, DC.

Pate JL and Hughes CK. 2017. Cell and networks the facilitate luteal survival for pregnancy success. Proceedings of the 4^th World Congress on Reproductive Biology, Okinawa, Japan.

Pate JL, Maalouf SA and Hughes CK. 2017. MicroRNA as regulators of luteal function. Proceedings of the 37^th annual meeting of the American Society of Reproductive Immunology, Chicago.

Kutchy NA, Menezes ESB, Wills RW, Tan W, Kaya A, Topper E, Didion BA, Moura AA, Perkins A, Memili E. (2017) Sperm Nuclear Proteins are Associated with Bull Fertility. Presented at the International Conference of Society for the Study of Reproduction. Washington, DC. July 13-16, 2017.

Kutchy NA, Menezes E, Moura A, Kaya A, Perkins A, Memili E. (2017) Sperm Epigenomic and Genomic Determinants Regulating Male Fertility. Gordon Research Conference on Fertilization & Activation of Development: Uniting Eggs and Sperm, from Fundamentals to Applications. Holderness, NH July 16-21, 2017.

Haynes, BP, Kutchy NA, Menezes ESB, Ugur MR, Tan W, Moura A, Kaya A, Memili E. (2017) Epigenetic Control of Male Fertility through Sperm Histone 4. Undergraduate Research Symposium, Mississippi State University, April 13, 2017.

Ugur MR, Kutchy NA, Menezes SBE, Kaya A, Moura A, Perkins A, Memili E. (2017) Sperm- and Oocyte-born MicroRNA Transcripts Regulating Early Mammalian Embryogenesis and Fertility. Mississippi State University’s Graduate Student Association’s Symposium, March 25, 2017.

Kutchy NA, Menezes ESB, Chiappetta A, Kaya A, Moura A, Perkins A, Memili E. (2017) Sperm Chromatin Dynamics Modulated by Acetylated and Methylated Sperm Histone 3 (H3K27ac and H3K27me3) are Associated with Male Fertility. Triangle Consortium for Reproductive Biology (TCRB) Conference, Research Triangle Park, NC, February 25, 2017.

Koganti PP, Wang J and Yao J. Identification and Functional Prediction of Bovine Oocyte-Specific Long Non-Coding RNAs. 50th Annual Meeting of the Society for the Study of Reproduction. Washington D.C. July 13-16, 2017.

Zhang M, Hand JM, Smith GW and Yao J. Determination of the consensus target sequences recognized by ZNFO, a novel oocyte-specific zinc finger transcription factor in cattle. 50th Annual Meeting of the Society for the Study of Reproduction. Washington D.C. July 13-16, 2017.

Harl, A.W., E.L. Larimore, A. Al Naib†, L.K. Wooldridge, A.D. Ealy, G.A. Perry and M.L. Rhoads. 2017. Maturation of bovine cumulus-oocyte complexes with follicle fluid varying in estradiol content affects cumulus cell expansion without affecting subsequent embryo development in vitro. 2017 IETS Annual Meeting, Austin, TX.

J.O. Giordano. Integrating automated detection of estrus in reproductive management programs for dairy cattle. Precision Dairy Management Conference. Lexington, KY. May 30th, 2017.

J.O. Giordano. Update on reproductive physiology and reproductive management programs of lactating dairy cows. Technical services training program. Boehringer Ingelheim Vetmedica. Portland, OR. June 22nd, 2017.

J.O. Giordano. Reproductive Physiology and Management of Dairy Cattle. Alta Genetics Dairy Manager School for Spanish speaking managers. Alta Genetics. Watertown, WI. July 17th and 18th, 2017.

J.O. Giordano. Reproductive Physiology and Management of Dairy Cattle. Alta Genetics Dairy Manager School for Spanish speaking managers. Alta Genetics. Tulare, CA. May 23rd, 2017.

J.O. Giordano. 1. Practical aspects of reproductive physiology. 2. Current reproductive management strategies for dairy cattle. Eastern New York Dairy Day. Cooperstown, NY. March 28th, 2017.

J.O. Giordano. Reproductive Physiology and Management of Dairy Cattle. Alta Genetics Dairy Manager School. Alta Genetics. Gainesville, FL. March 9th, 2017.

J.O. Giordano. Reproductive Physiology and Management of Dairy Cattle. Alta Genetics Dairy Manager School. Alta Genetics. Gainesville, FL. February 20th, 2017.

J.O. Giordano. Ohio Dairy Health and Management Certificate Program: Dairy Cattle Reproduction with Emphasis on Transition Cow Management in Confinement Systems. 1. Automating Health Monitoring in Dairy Farms. 2. Automating Health Monitoring in Dairy Farms. College of Veterinary Medicine, The Ohio State University, Columbus, Ohio. February 2nd, 2017.

J.O. Giordano. Automating Reproductive and Health Management in Dairy Farms. GEA Technologies technical services team training program. Puerto Vallarta, Mexico. January 18th, 2017.

 

Extension reports:

Romereim SM, Tenley SC, Abedal-Majed MA, Bergman JW, Kurz SG, Davis JS, Wood JR, and Cupp AS (2017) Letrozole: A Steroid-Free Estrous Synchronization Method. Nebraska 2017 Beef Cattle Report, in press

 

Theses/Dissertations:

Abedal-Majed, MA (2017) Effect of Post-Weaning Diet, Excess Androstenedione, and Vascular Endothelial Growth Factor A (VEGFA) Isoforms on Follicular Progression in Bovine Ovarian Cortical Cultures (Nebraska).

Joseph Miseirvitch (2017). Regulation of CCN1 Expression by PGF and PKC Signaling in Human Ovarian Granulosa Cells (New Hampshire).

McCauley Vailes (2017). Post-Transfer Outcomes in Cultured Bovine Embryos Supplemented with Epidermal Growth Factor, Fibroblast Growth Factor 2, and Insulin-Like Growth Factor 1. (Virginia).

Benjamin R. Crites (2017).  Comparison of conception rates in beef cattle inseminated with either SEXEDULTRA™ sex-sorted semen or conventional semen in fixed-time artificial insemination (FTAI) protocols (Kentucky).

Benjamin Hale (2017). Two components of maintaining developmental competence: MicroRNA-21 in the maturing oocyte and autophagy induction in the follicular stage ovary (Iowa).

Katie L. Bidne (2017). Investigating the ovarian response to endotoxemia (Iowa).

Mackenzie J. Dickson (2017). Impact of endotoxemia on ovarian signaling and function (Iowa).

 

Active collaboration within the group

NY, PA, NH, VT and WV:  Samples collected to investigate associations between fertility outcomes and SNP in candidate genes from dairy cows.

IA and UK: Samples shared to determine the effect of LPS treatment on ovarian inflammation.

PA and WV: Samples shared for analysis of molecular regulators of luteal function.

VT and NY: Samples assayed (NY) for analysis of progesterone concentrations.

NY and WI:  Samples collected to investigate the effect of supplementation with rumen-protected methionine on reproductive traits of lactating dairy cows.

 

In addition to Hatch Multistate Funds, these studies were supported by:

National Institute of Environmental Health Science (AK)     

National Institutes of Health (FD)

USDA-National Institute of Food and Agriculture (AK, PB, JP, EM, MR, AE, SHC, JG, MW)

USDA-ARS Specific Cooperative Agreement (SCA) with the Forage and Animal Production Research Unit (FAPRU), Lexington, KY (PB)

Virginia Agricultural Council Research Funding (AE, MR)

Iowa Pork Producers Association (AK)                                                                                             

National Pork Board (AK)

National Institute of Food and Agriculture (AK)

Iowa Pork Industry Center (AK)

Iowa State University Bailey Career Development Award (AK)

Lee Rumberger and Family Endowment (JP)

Alta Genetics, Inc. (EM)

Brasil Programa de Doutorado Integrado em Zootecnia – PDIZ/UFC and Conselho Nacional de Desenvolvimeno Científico e Tecnológico – CNPq (EM)

New York Farm Viability Institute (JG)

Adisseo (JG, MW)

Zoetis (JG)

 

08/19/2019

Peer-reviewed journal articles reporting research from this project

 

Abuajamieh, M, Kvidera, SK, Mayorga, EJ, Kaiser, A, Lei, S, Seibert, JT, Horst, EA, Sanz Fernandez, MV, Ross, JW, Selsby, JT, Keating, AF, Rhoads, RP, Baumgard, LH 2018. The effect of recovery from heat stress on circulating bioenergetics and inflammatory biomarkers. Journal of Animal Science. 96(11):4599-4610.

 

Horst, EA, Kvidera, SK, Mayorga, EJ, Shouse, CS, Al-Qaisi, M, Dickson, MJ, Ydstie, J, Ramirez Ramirez, HA, Keating, AF, Dickson, DJ, Griswold, KE, Baumgard, LH. 2018. Effect of chromium on bioenergetics and leukocyte dynamics following immunoactivation in lactating Holstein cows. Journal of Dairy Science. 101(6):5515-5530.

 

Hristov, AN,  Degaetano, AT,  Rotz, CA, Hoberg, E, Skinner, RH, Felix, T, Li, H, Patterson, PH, Roth, G, Hall, M, Ott, TL, Baumgard, LH, Staniar, W, Hulet, RM, Dell, CJ, Brito, AF, Hollinger, DY. 2018. Climate change effects on livestock in the Northeast US and strategies for adaptation. Climatic Change 146 (1-2); pgs 33-45 doi.org/10.1007/s10584-017-2023-z

 

Hughes CK, Maalouf SW Liu W-S, Pate JL. 2019. Molecular profiling demonstrates modulation of immune cell function and matrix remodeling during luteal rescue. Biology of Reproduction, 2019, 0(0), 1–16 doi:10.1093/biolre/ioz037 Research Article Advance Access Publication Date: 27 March 2019

 

Hughes CK, Pate JL. 2019. Luteolysis and the Corpus Luteum of Pregnancy. In: The Ovary 3rd Edition, PCK Leung and EY Adashi, eds., Academic Press, Elsevier, pp. 270-295.  ISBN 978-0-12-813209-8

 

Ott, TL. 2019. Symposium Review: Immunological detection of the ruminant conceptus. Journal of Dairy Science 104(4): pgs 3766-3777 doi.org/10.3168/jds.2018-15668 

 

Pate JL, Hughes CK. 2018. Applications of large-scale molecular profiling techniques to the study of the corpus luteum. Anim. Reprod. 15:Suppl. 1, p. 791-804. DOI: 10.21451/1984-3143-AR2018-0038

 

Pate, JL. 2018. Luteolysis. In M. K. Skinner (Ed.), Encyclopedia of Reproduction. vol. 2, pp. 106–113. Academic Press: Elsevier. http://dx.doi.org/10.1016/B978-0-12-801238-3.64397-0

 

Silveira, PAS, WR Butler, SE LaCount, TR Overton, CC Barros, and A Schneider. 2019. Polymorphisms in the anti-oxidant paraoxonase-1 (PON1) gene associated with fertility of postpartum dairy cows. Theriogenology 125:302-309.

 

Bedford A, Beckett L, Hardin K, Dias NW, Davis T, Mercadante VR, Ealy AD and White RR. 2018. Propionate affects insulin signaling and progesterone profiles in dairy heifers. Sci. Rep. 8:17629.

 

Bonometti S, Menarim BC, Reinholt BM, Ealy AD and Johnson SE. 2019. Growth factor modulation of equine trophoblast mitosis and prostaglandin gene expression. J. Anim. Sci. 97:865-873. 

 

Ealy AD, Wooldridge LK and McCoski SR. 2019. Post-transfer consequences of in vitro-produced embryos in cattle. J. Anim. Sci. ePub 04/10/2019. 

 

Fontes PL, Oosthuizen N, Ciriaco FM, Sanford CD, Canal LB, Pohler KG, Henry DD, Mercadante VR, Timlin CL, Ealy AD, Johnson SE, DiLorenzo N and Lamb GC. 2019. Impact of fetal vs. maternal contributions of Bos indicus and Bos taurus genetics on embryonic and fetal development. J. Anim. Sci. 97:1645-1655.

 

McCoski SR, Poole RK, Vailes MT and Ealy AD. 2018. Maternal obesity alters the expression of embryonic regulatory transcripts in the preimplantation ovine conceptus. Repro. Biol. 18:198-201.

 

McCoski SR, Vailes MT, Owens, CE Cockrum RR and Ealy AD. 2018. Exposure to maternal obesity alters gene expression in the preimplantation ovine conceptus. BMC Genomics 19:737.

 

Vailes MT, McCoski SR, Wooldridge LK, Reese ST, Pohler KG, Roper DA, Mercadante VR and Ealy AD. 2019. Post-transfer outcomes in cultured bovine embryos supplemented with epidermal growth factor, fibroblast growth factor 2, and insulin-like growth factor 1. Theriogenology 124:1-8.

 

Wooldridge LK and Ealy AD. 2019. Interleukin-6 increases inner cell mass numbers in bovine embryos. BMC Dev. Biol. 19:2.

 

Zhang Z, Zhao LD, Johnson SE, Rhoads ML, Jiang H and Rhoads RP. 2019. Oxytocin is involved in steroid hormone-stimulated bovine satellite cell proliferation and differentiation in vitro. Domest. Anim. Endocrinol. 66:1-13.

 

Carvalho PD, Santos VG, Giordano JO, Wiltbank MC, Fricke PM. 2018. Development of fertility programs to achieve high 21-day pregnancy rates in high-producing dairy cows. Theriogenology 2018; 114:165-172.  10.1016/j.theriogenology. 03.037

 

Garcia-Guerra A, Canavessi AMO, Monteiro PLJ, Jr., Mezera MA, Sartori R, Kirkpatrick BW, Wiltbank MC. 2018. Trio, a novel bovine high fecundity allele: III. Acquisition of dominance and ovulatory capacity at a smaller follicle size. Biol Reprod 98:350-365.  10.1093/biolre/iox157

 

Garcia-Guerra A, Kamalludin MH, Kirkpatrick BW, Wiltbank MC. 2018. Trio a novel bovine high-fecundity allele: II. Hormonal profile and follicular dynamics underlying the high ovulation rate. Biol Reprod 98:335-349.  10.1093/biolre/iox156

 

Garcia-Guerra A, Wiltbank MC, Battista SE, Kirkpatrick BW, Sartori R. 2018. Mechanisms regulating follicle selection in ruminants: lessons learned from multiple ovulation models. Animal Reproduction 15:660-679. 

 

Kamalludin MH, Garcia-Guerra A, Wiltbank MC, Kirkpatrick BW. 2018. Proteomic analysis of follicular fluid in carriers and non-carriers of the Trio allele for high ovulation rate in cattle. Reprod Fertil Dev  10.1071/RD17252

 

Kamalludin MH, Garcia-Guerra A, Wiltbank MC, Kirkpatrick BW. 2018. Trio, a novel high fecundity allele: I. Transcriptome analysis of granulosa cells from carriers and noncarriers of a major gene for bovine ovulation rate. Biol Reprod 98:323-334.  10.1093/biolre/iox133

 

Melo LF, Monteiro PLJ, Jr., Nascimento AB, Drum JN, Spies C, Prata AB, Wiltbank MC, Sartori R. 2018. Follicular dynamics, circulating progesterone, and fertility in Holstein cows synchronized with reused intravaginal progesterone implants that were sanitized by autoclave or chemical disinfection. J Dairy Sci 101:3554-3567.  10.3168/jds.2017-13570

 

Melo LF, Monteiro PLJ, Jr., Oliveira LH, Guardieiro MM, Drum JN, Wiltbank MC, Sartori R. 2018. Circulating progesterone concentrations in nonlactating Holstein cows during reuse of intravaginal progesterone implants sanitized by autoclave or chemical disinfection. J Dairy Sci 101:3537-3544.  10.3168/jds.2017-13569

 

Ochoa JC, Penagaricano F, Baez GM, Melo LF, Motta JCL, Garcia-Guerra A, Meidan R, Pinheiro Ferreira JC, Sartori R, Wiltbank MC. 2018. Mechanisms for rescue of corpus luteum during pregnancy: gene expression in bovine corpus luteum following intrauterine pulses of prostaglandins E1 and F2alpha. Biol Reprod 98:465-479.  10.1093/biolre/iox183

 

Silva EP, Wiltbank MC, Machado AB, Gambin LS, Dias MM, Chaiben MFC, Bernardi ML, Borges JBS. 2018. Optimizing timed AI protocols for Angus beef heifers: Comparison of induction of synchronized ovulation with estradiol cypionate or GnRH. Theriogenology 121:7-12.  10.1016/j.theriogenology.2018.07.019

 

Vasconcelos JLM, Pereira MHC, Wiltbank MC, Guida TG, Lopes Jr. FR, Sanches Jr. CP, Barbosa LFSP, Costa Jr. WM, Munhoz AK. 2018. Evolution of fixed-time AI in Brazil. Animal Reproduction 15: 940-951. 

 

Wiltbank MC, Mezera MA, Toledo MZ, Drum JN, Baez GM, Garcia-Guerra A, Sartori R. 2018. Physiological mechanisms involved in maintaining the corpus luteum during the first two months of pregnancy. Animal Reproduction 15:805-821.

 

Tenley SC, Spuri-Gomes R, Rosasco SL, Northrop EJ, Rich J, McNeel AK, Summers AF, Miles JR, Chase CC, Lents CA, Perry GA, Wood JR, Cupp AS, Cushman RA. 2018. Maternal Age Influences the Number of Primordial Follicles in the Ovaries of Yearling Angus Heifers, Animal Reproduction Science 200:105-112

 

McFee RM, Cupp AS, and Wood JR. 2018. Use of case-based or hands-on lab exercises with physiology lectures improves knowledge retention but veterinary medicine students prefer case-based activities, Adv Physiology Education, 42(2):182-191

 

Wood JR, and Cupp AS. 2018. Aromatization. In M. K. Skinner (Ed.), Encyclopedia of Reproduction. vol. 2, pp. 195–201. Academic Press: Elsevier. http://dx.doi.org/10.1016/B978-0-12-801238-3.64642-1

 

Ganesan, S, Dickson, MJ, Keating, AF. 2018. Pesticides. In M. K. Skinner (Ed.), Encyclopedia of Reproduction. vol. 2, pp. 724–730. Academic Press: Elsevier.

Clark, KL, Ganesan, S, Keating, AF. 2018. Impact of Toxicant Exposures on Ovarian Gap Junctions. Reproductive Toxicology. 81:140-146.

Bidne, KL, Dickson, MJ, Ross, JW, Baumgard, LH, Keating, AF. 2018. Disruption of female reproductive function by endotoxins. Reproduction. 155(4):R169-R181.

 

 

Conference papers and abstracts/presentations

Clark, KL, Talton, O, Ganesan, A, Schulz, LC, Keating AF. 2018. Lean maternal gestational diabetes mellitus impacts the ovarian proteome basally and in response to a stressor in later life. Society for the Study of Reproduction annual meeting, New Orleans.

 

Parrish, JJ, Keating, AF, Pate, JL, Pohler, KG, Wiltbank, MC, Ealy, AD. 2018. Changing paradigm in graduate education: Collaborative on-line approach in Reproduction. American Society of Animal Science annual meeting.

 

Piet S, Walker S, Tsang PCW.  2019. Expression and Regulation of Cysteine Rich 61-Connective Tissue Growth Factor-Nephroblastoma Overexpressed (CCN1) in Ovarian Adenocarcinoma (OVCAR8) Cells. 52nd Annual Meeting of the Society for the Study of Reproduction, San Jose, CA.

 

Wiltbank MC, Carvalho PD, Barletta RV, Fricke PM, Shaver RD. 2018. Relationships Among Changes in Body Condition Score and Reproductive Efficiency in Lactating Dairy Cows. 27th Tri-State Dairy Nutrition Conference 2018:121-138. 

 

Goulet M, Donahue J, Tsang PCW. 2019. Regulation of the Angiogenic Inducer, Cysteine Rich 61-Connective Tissue Growth Factor-Nephroblastoma Overexpressed 1 (CCN1), in Bovine Luteal Cells. 52nd Annual Meeting of the Society for the Study of Reproduction, San Jose, CA.

 

Lundberg, Jaskiewicz NJ, Townson DH. 2019. Stimulatory effects of Transforming Growth Factor-alpha in bovine granulosa cells of small antral follicles. Society for the Study of Reproduction Annual Meeting

 

Arbeithuber B, Stoler N, Higgins B, Hester JM, Diaz F, Nekrutenko A, Makova KD. 2018. Rare mitochondrial DNA variant analysis in single oocytes using duplex sequencing. 31st annual meeting of The Biology of Genomes. Cold Springs Harbor Laboratory.  Cold Springs Harbor, NY. May 8-12.

 

Baddela VS, Hughes CK and Pate JL. 2018. Let7 miRNA are abundant in the bovine corpus luteum and regulate cellular metabolic functions Society for the Study of Reproduction, New Orleans, LA

 

Butler WR, Schneider A, Silveira PAS, Townson DH, Tsang PCW, Dailey RA, Ott TL and Pate JL. 2018. Effects of polymorphisms in GHR, IGF-I and TNFα genes on fertility in lactating dairy cows. Amer Dairy Sci Association

 

Butler, W.R., Schneider., A., Silveira. P.A.S., Townson, D.H., Tsang, P.C.W., Dailey, R.A., Diaz FJ. 2018. Sufficient Dietary Zinc During the Preconception Period is Essential for Oocyte Competence.  Endocrine Society Annual Meeting, Chicago, IL. March 17-20.

 

Harper, MT, Oh, J, Melgar, A, Nedelkov, K, Räisänen, S, Chen, X, Martins, CMMR, Young, M, Ott,TL, Kniffen, DM, Fabin, R, Hristov, AN. 2018. Production effects of extruded soybean meal in early lactation cow diets. Journal of Dairy Science, 102 (Suppl 2) Abst: 510.

 

Hester JM and Diaz FJ. 2018. Growing Oocytes Need Zinc: Zinc Deficiency in the Preantral Ovarian Follicle.  Experimental Biology Meeting, San Diego CA.  *Endocrinology and metabolism section research recognition award.

 

Hughes CK, Maalouf SW Liu W-S, Pate JL. 2019. Molecular profiling demonstrates modulation of immune cell function and matrix remodeling during luteal rescue. Biology of Reproduction, 2019, 0(0), 1–16 doi:10.1093/biolre/ioz037 Research Article Advance Access Publication Date: 27 March 2019

 

Hughes CK, Rogus A, Inskeep EK and Pate. 2018. Functional transitions in the corpus luteum are associated with changes in NR5A2 abundance, which regulates luteal progesterone production. Proc. 10th Int Ruminant Reprod Symp, Foz do Iguacu, Brazil

 

Hughes CK, Wetzel LM, Bosviel R, Newman J and Pate JL. 2018. Luteal metabolomics suggests a role for lipid mediators as regulators of cell death, cell migration, and immune function. Society for the Study of Reproduction, New Orleans, LA

 

Lupicka M and Pate JL. 2018. Luteal Extracellular Vesicles Carry MicroRNA and Modulate Cytokine Secretion from Immune Cells. Society for the Study of Reproduction, New Orleans, LA

 

Melgar, A, Harper, MT, Oh, J, Giallongo, F, Fetter, ME, Ott, TL, Duval, S, Hristov, AN. 2018. Effects of 3-nitrooxypropanol on rumen fermentation, lactational performance, and onset of ovarian activity in dairy cows. Journal of Dairy Science, 102 (Suppl 2) Abst: 209.

 

Ott, TL, Pate, JL. 2018. Effects of polymorphisms in GHR, IGFI and TNFA genes on fertility in lactating dairy cows. Journal of Dairy Science, 102 (Suppl 2) Abst. T207

 

Ott, TL., 2018. Immune recognition of the periattachment conceptus. Journal of Dairy Science, 102 (Suppl 2) Abst; 102.

 

Pate JL and Hughes CK. 2018. Applications of large-scale molecular profiling techniques to the study of the corpus luteum. Proc 10th Intl Ruminant Reproduction Symposium, Foz do Iguacu, Brazil

Ealy AD. 2019. Early Diagnosis of Pregnancy Loss. American Dairy Science Association Annual Meeting, Cincinnati OH.

 

Wooldridge LK, Johnson SE and Ealy AD. 2019. Interleukin-6 increases inner cell mass and hypoblast cell numbers in bovine blastocysts. Society for the Study of Reproduction 52nd Annual Meeting, San Jose CA.

 

Wooldridge LK and Ealy AD. 2019. STAT3 is required for hypoblast lineage development in bovine blastocysts. 2019. Society for Developmental Biology 78th Annual Meeting, Boston MA.

 

Cushman RA, Tenley SC, Spuri-Gomes R, Rosasco SL, Northrop EJ, Rich JRR, McNeel AK, Summers AF, Miles JR, Chase C, Lents CA, Perry GA, Wood JR, and Cupp AS. 2018. Influence of Maternal Age on Daughter Ovarian Reserve and Reproductive Longevity in Beef Cows. 51st Annual Meeting of the Society for the Study of Reproduction, New Orleans, LA

 

Neilson MA, Spuri-Gomes R, Romereim SM, Summers AF, Abedal-Majed MA, Tenley SC, Kurz SG, Bergman J, Davis JS, Wood JR, and Cupp AS. 2018. Altered Blood Plasma and Follicular Fluid Lipid Profiles Suggest Possible Discrepancies in Cell Signaling and Metabolism in Cows with Androgen Excess. 51st Annual Meeting of the Society for the Study of Reproduction, New Orleans, LA

 

Snider AP, Romereim SM, Summers AF, Pohlmeier WE, McFee RM, Spuri-Gomes R, Kurz SG, Davis JS, Wood JR, and Cupp AS. 2018. Exposure to Excess Androgen in the Ovarian Microenvironment of High A4 Cows Results in Altered Function of Granulosa Cells which may Explain Changes in Cyclicity and Response to Male Exposure. 51st Annual Meeting of the Society for the Study of Reproduction, New Orleans, LA

 

Hart ML, Abedal-Majed MA, Spuri-Gomes R, Snider AP, Kurz SG, Bergman JW, McFee RM, Casey CA, Davis JS, Cushman RA, Wood JR, and Cupp AS. 2018. Cyclicity Phenotype and Ovarian Cortex Androgen Secretion in Androgen Excess Cows are Predictive of Plasma Steroid and Lipids, Liver Enzymes, and Follicular Fluid Cytokines. 51st Annual Meeting of the Society for the Study of Reproduction, New Orleans, LA

 

Bochantin KA, Summers AF, Pohlmeier WE, Sargent KM, Kurz SG, Romereim SM, Daudu O, McFee RM, Cushman RA, Davis JS, Cupp AS, Wood JR. 2018.  Microarray Analysis Predicts that Differentially Expressed Genes in Theca Cells from Cows with High Intrafollicular Androstenedione are Regulated by ESR1 and VEGFA Signaling and Increased mRNA Stability. 51st Annual Meeting of the Society for the Study of Reproduction, New Orleans, LA

 

Timme KR, Miller HB, and Wood JR. Signaling of Pro-Inflammatory Cytokine TNFa through NFkB-p65 Increases Gdf9 and Decreases Figla mRNAs in Oocytes of Primary Follicles. 2018. 51st Annual Meeting of the Society for the Study of Reproduction, New Orleans, LA

 

McCain AR, Rister AL, Wordekemper M, Dodds ED, and Wood JR. 2018. Maternal obesity due to diet or loss of satiety differentially impacts fetal growth and placental efficiency which may be due to differences in excess circulating lipids. 51st Annual Meeting of the Society for the Study of Reproduction, New Orleans, LA

 

Theses/Dissertations

 

Hester, JM. The impact of zinc deficiency during oogenesis, follicle assembly, and growth. PhD Thesis in Physiology, Pennsylvania State University. Dec 2018.

 

Audra Harl. 2018. Factors affecting the quality and function of the bovine periovulatory follicle. (PhD Dissertation).

 

Sarah McCoski. 2018. Manipulating embryonic development and endometrial function in ruminants. (PhD Dissertation).

 

Lundberg, Townson DH. 2019 Investigation of Transforming Growth Factor-α and its potential role in promoting ovarian follicular dominance. UVM MS Thesis

 

Active collaboration within the group

 

NY, PA, NH, VT and WV:  Samples collected to investigate associations between fertility outcomes and SNP in candidate genes from dairy cows.

 

IA and UK: Samples shared to determine the effect of LPS treatment on ovarian inflammation.

 

PA and WV: Samples shared for analysis of molecular regulators of luteal function.

 

VT and NY: Samples assayed (NY) for analysis of progesterone concentrations.

 

 

In addition to Hatch Multistate Funds, these studies were supported by:

 

Iowa Pork Producers Association                                                                                               

 

National Pork Board

 

ISU Nutritional Sciences Council Martin Fund    

 

National Institute of Environmental Health Science - Agriculture and Food Research Initiative

 

National Institutes of Health

 

C. Lee Rumberger and Family Endowment

 

John L. Pratt Animal Nutrition Program

 

Virginia Agricultural Council Research Funding

 

University of Nebraska Foundation Funds

08/13/2020

Peer-reviewed journal articles reporting research from this project

Abedal-Majed MA, Kurz SG, Springman SA, McNeel AK, Freetly HC, Largen V, Magamage M, Sargent KM, Wood JR, Cushman RA, Cupp AS (2019) Vascular endothelial growth factor A isoforms modulate follicle development independent of diet in peri-pubertal heifers through diverse signal transduction pathways. Biol Reprod 102: 680-692, PMID: 31723977 

Akin, E.E., Johnson, A.K., Ross, J.W., Millman, S.T., Jass, C.D., Stinn, J.P., Stalder, K.J. 2019. Modified wean-to-finish mat as an alternative handling tool for moving grow-finish pig cadavers: A pilot study. Journal of Swine Health and Production 27:278-283.

Aldrigde EM, Fearon JE, Haynes PB, Miller HM, Sanford KY, Scott RR, Anglin WW, Blolack LS, Burkes BL, Cohn-White OL, Franks BR, Giles HM, Greene AL, Hanby RD, Holliman AG, Kirby JM, Klein AU, Lehman CA, Lloyd GJ, Lore CT, McMurray TB, Moody ZV, Palmer BN, Pansano LV, Pickle RM, Schaeffer LM, Sidl JR, Smith JD, Stepp HF, Satrio FA, Kutchy NA, Dechert E, Rutherford C, Brown K, Purwantara B, Memili E. (2019) Solutions for grand challenges in goat and sheep production. BIOTROPIA. 26(1): 56-64.

Basavaraja, R., S. T. Madusanka, J. N. Drum, K. Shrestha, S. Farberov, M. C. Wiltbank, R. Sartori, and R. Meidan. 2019. Interferon-Tau Exerts Direct Prosurvival and Antiapoptotic Actions in Luteinized Bovine Granulosa Cells. Sci Rep 9:14682.

Bidne, K.L., Romoser, M.R., Ross, J.W., Baumgard, L.H., Keating, A.F. 2019. Heat stress during the luteal phase decreases luteal size but does not impact circulating progesterone in gilts. Journal of Animal Science. 97(10):4314-4322.

Boettcher, A.N., Kiupel, M., Adur, M.K., Cocco, E., Santin, A.D., Bellone, S., Charley, S.E., Blanco-Fernandez, B., Risinger, J.I., Ross, J.W., Tuggle, C.K., Shapiro, E.M. 2019. Human Ovarian Cancer Tumor Formation in Severe Combined Immunodeficient (SCID) Pigs.  Front Oncol.

Bonometti S, Menarim BC, Reinholt BM, Ealy AD and Johnson SE. Growth factor modulation of equine trophoblast mitosis and prostaglandin gene expression. J Anim Sci. 2019 Feb 1;97(2):865-873. doi: 10.1093/jas/sky473.

Carlisle LD, Memili E, Linford BL, Slater KA, Nicodemus MC. (2019) Relationship Between Gait Mechanics and the Speed of the Trot in the Weimaraner Dog Breed. Topics in Companion An Med. 35:26-30.

Clark, K.L., Talton, O.O., Ganesan, S., Schulz, L.C., Keating, A.F. 2019. Developmental Origins of Ovarian Disorder: Impact of Maternal Lean Gestational Diabetes on the Offspring Ovarian Proteome in Mice. Biology of Reproduction. 101(4):771-781.

Dickson, M.J., Kvidera, S.K., Horst, E.A., Wiley, C.E., Mayorga, E.J., Ydstie, J., Perry, G.A., Baumgard, L.H., Keating, A.F. 2019. Impact of chronic and increasing lipopolysaccharide exposure on production and reproductive parameters in lactating Holstein dairy cows. Journal of Dairy Science. 102(4):3569-3583.

Dolecheck KA, Garcia-Guerra A, Moraes LE. 2019 Quantifying the effects of mastitis on the reproductive performance of dairy cows: A meta-analysis. Journal of Dairy Science, 102 (9): 8454–8477.

Ealy AD and Seekford ZK. Symposium Review: Predicting pregnancy loss in dairy cattle. J Dairy Sci. 2019; 102:11798-11804. doi: 10.3168/jds.2019-17176.

Ealy AD, Wooldridge LK and McCoski SR. Board Invited Review: Post-transfer consequences of in vitro-produced embryos in cattle. J Anim Sci. 2019 May 30;97(6):2555-2568. doi: 10.1093/jas/skz116.

El Debaky HA, Kutchy NA, Ul-Husna A, Intriastuti R, Akhter S, Purwantara B, Memili E. (2019) Potential of water buffalo in world agriculture: challenges and opportunities. Applied Animal Science. 35:255-268.

Evans H, Jousan D, Memili E, Beckman L, Nicodemus H. (2019) Life skill development and financial impact associated with a youth livestock sales program. Journal of Youth Development 14(3).

Figueroa-Morales N, Dominguez-Rubio L, Ott TL, Aranson IS. 2019. Mechanical shear controls bacterial penetration in mucus. Sci Rep. 4;9(1):9713. doi: 10.1038/s41598-019-46085-z. PubMed PMID: 31273252; PubMed Central PMCID: PMC6609767.

Fontes PL, Oosthuizen N, Ciriaco FM, Sanford CD, Canal LB, Pohler KG, Henry DD, Mercadante VR, Timlin CL, Ealy AD, Johnson SE, DiLorenzo N and Lamb GC. Impact of fetal vs. maternal contributions of Bos indicus and Bos taurus genetics on embryonic and fetal development. J Anim Sci. 2019 Apr 3;97(4):1645-1655. doi: 10.1093/jas/skz044.

Garcia-Guerra A, Sala RV, Carrenho-Sala L, Baez GM, Motta JCL, Fosado M, Moreno JF, Wiltbank MC. 2019 Postovulatory treatment with GnRH on day 5 reduces pregnancy loss in recipients receiving an in vitro produced expanded blastocyst. Theriogenology, 141: 202-210.

Gomes FP, Diedrich JK, Saviola AJ, Memili E, Moura AA, Yates JR. (2020) EThcD and 213 nm UVPD for Top-Down Analysis of Bovine Seminal Plasma Proteoforms on Electrophoretic and Chromatographic Time Frames. Anal Chem. doi: 10.1021/acs.analchem.9b03856.

Gomez-Leon, V. E., O. J. Ginther, E. R. Araujo, J. D. Guimaraes, and M. C. Wiltbank. 2019. Hormonal mechanisms regulating follicular wave dynamics I: Comparison of follicle growth profiles under different physiological conditions in heifers. Theriogenology 123:194-201.

Gomez-Leon, V. E., O. J. Ginther, J. D. Guimaraes, and M. C. Wiltbank. 2020. Hormonal mechanisms regulating follicular wave dynamics II: Progesterone decreases diameter at follicle selection regardless of whether circulating FSH or LH are decreased or elevated. Theriogenology 143:148-156.

Habeeb et al. Effect of different dosages of PG-600 on ovulation and pregnancy rates in ewes during the breeding season. Transl. Anim. Sci. 2019.3:429–432.

Habeeb et al. Ovulation, pregnancy, and lambing rates during nonbreeding season with or without exogenous gonadotropin stimulation. Clinical Theriogenology 2020.12:23-28. 

Habeeb et al. Endometrial estrogen receptor, follicle stimulating hormone receptor, and mucin-1 expression during early diestrus in ewes following PG-600 administration. In review, Reproduction in Domestic Animals, April 30, 2020.

Harl A, Westfall-Rudd D and Rhoads ML. 2019. Increased utilization of tactile activities in reproductive physiology laboratory sections to improve cognitive learning. NACTA J. 2019 63(2):341-343. 

Harper MT, Oh J, Melgar A, Nedelkov K, Räisänen S, Chen X, Martins CMMR, Young M, Ott TL, Kniffen DM, Fabin RA, Hristov AN. 2019. Production effects of feeding extruded soybean meal to early-lactation dairy cows. J Dairy Sci. 102(10):8999-9016. doi: 10.3168/jds.2019-16551. Epub 2019 Aug 14. PubMed PMID: 31421886.

Hines, E.A., Romoser, M.R., Kiefer, Z.E., Keating, A.F., Baumgard, L.H., Niemi, J., Haberl, B., Williams, N.H., Kerr, B.J., Touchette, K.J., Ross, J.W. 2019. The impact of dietary supplementation of arginine during gestation in a commercial swine herd: II. Offspring performance. Journal of Animal Science. 97(9):3626-3635. 

Hines, E.A., Romoser, M.R., Kiefer, Z.E., Keating, A.F., Baumgard, L.H., Niemi, J., Gabler, N.K., Patience, J.F., Haberl, B., Williams, N.H., Kerr, B.J., Touchette, K.J., Ross, J.W. 2019. The impact of dietary supplementation of arginine during gestation in a commercial swine herd: I. Gilt reproductive performance. Journal of Animal Science. 97(9):3617-3625.

Horst, E.A., Kvidera, S.K., Dickson, M.J., McCarthy, C.S., Mayorga, E.J., Al-Qaisi, M., Ramirez, A.A., Keating, A.F., Baumgard, L.H. 2019. Effects of continuous and increasing lipopolysaccharide infusion on basal and stimulated metabolism in lactating Holstein cows. Journal of Dairy Science. 102(4):3584-3597.

Hughes CHK, Inskeep EK, Pate JL. 2020. Temporal changes in the corpus luteum during early pregnancy reveal regulation of pathways that enhance steroidogenesis and suppress luteolytic mechanisms. Biology of Reproduction. https://doi.org/10.1093/biolre/ioaa047.

Hughes CK, Pate JL. 2019. Luteolysis and the Corpus Luteum of Pregnancy. In: The Ovary 3rd Edition, PCK Leung and EY Adashi, eds., Academic Press, Elsevier, pp. 270-295.  ISBN 978-0-12-813209-8

Hughes CK, Maalouf SW Liu W-S, Pate JL. 2019. Molecular profiling demonstrates modulation of immune cell function and matrix remodeling during luteal rescue. Biology of Reproduction, 2019, 100(6), 1581–1596 doi:10.1093/biolre/ioz037

Hughes CHK, Bosviel R, Newman JW, Pate JL. 2019. Luteal lipids regulate progesterone production and may modulate immune cell function during the estrous cycle and pregnancy. Front. Endocrinol. 10:662.  doi: 10.3389/fendo.2019.00662

Jaskiewicz NJ, Townson DH (2019) Hyper-O-GlcNAcylation promotes epithelial-mesenchymal transition in endometrial cancer cells. Oncotarget 10(30):2899-2910

Khanal, P., Sanglard, L.P., Mayberry, K., Sommer, J., Poore, M.H., Poole, D.H., Serão N.V.L. 2019 Identification of differentially expressed genes for fescue toxicosis in high and low tolerant Angus cows. Epigenetics & Genomics DOI: 10.21203/rs.2.9998/v1

Kshitiz, Afzal J, Maziarz JD, Hamidzadeh A, Liang C, Erkenbrack EM, Kim HN, Haeger JD, Pfarrer C, Hoang T, Ott T, Spencer T, Pavličev M, Antczak DF, Levchenko A, Wagner GP. Evolution of placental invasion and cancer metastasis are causally linked. Nat Ecol Evol. 2019 Dec;3(12):1743-1753. doi: 10.1038/s41559-019-1046-4. Epub 2019 Nov 25. PubMed PMID: 31768023.

Kutchy NA, Dogan S, Wang X, Topper E, Kaya A, Memili E. (2020) Application of Proteomics to Identify Fertility Markers in Angus Bull Sperm. In press; HAYATI Journal of Biosciences. 

Kutchy NA, Menezes ESB, Ugur MR, Ulhusna A, ElDebaky H, Evans HC, Beaty E, Santos F, Tan W, Wills RW, Topper E, Kaya A, Moura AA, Memili E. (2019) Sperm Cellular and Nuclear Dynamics Associated with Bull Fertility. Anim Reprod Sci. Dec;211:106203. doi: 10.1016/j.anireprosci.2019.106203. Epub 2019 Oct 18. PMID: 31785643

Li H, Garner TB, Diaz FJ and Wong PK. A Multiwell Microfluidic Device for Analyzing and Screening Non-Hormonal Contraceptive Agents. Small. (2019) Jul;15(28):e1901910. 

Macedo, G. G., R. D. Mingoti, E. O. S. Batista, B. M. Monteiro, L. M. Vieira, R. V. Barletta, M. C. Wiltbank, G. P. Nogueira, F. P. Renno, J. R. Maio, and P. S. Baruselli. 2019. Profile of LH release in response to intramuscular treatment with kisspeptin in Bos indicus and Bos taurus prepubertal heifers. Theriogenology 125:64-70.

Mayorga, E.J., Kvidera, S.K., Horst, E.A., Al-Qaisi, M., Dickson, M.J., Seibert, J.T., Lei, S., Keating, A.F., Ross, J.W., Rhoads, R.P., Rambo, Z.J., Wilson, M.E., Baumgard, L.H. 2019 Effects of zinc amino acid complex on biomarkers of gut integrity and metabolism during and following heat stress or feed restriction in pigs.  Journal of Animal Science 96:4173-4185.

Mayorga, E.J., Kvidera, S.K., Seibert, J.T., Horst, E.A., Abuajamieh, M., Al-Qaisi, M., Lei, S., Ross, J.W., Johnson, C.D., Kremer, B., Ochoa, L., Rhoads, R.P., Baumgard, L.H.  2019. Effects of dietary chromium propionate on growth performance, metabolism, and immune biomarkers in heat-stressed finishing pigs. J Anim Sci. 97:1185-1197.

Mayorga E.J., Renaudeau, D., Ramirez, B.C., Ross, J.W., Baumgard, L.H. 2019.  Heat stress adaptation in pigs. Animal Frontiers 9:54-61.

Memili E, Moura A, Kaya A. (2020) Metabolomes of Sperm and Seminal Plasma Associated with Bull Fertility. Animal Reproduction Science. doi: 10.1016/j.anireprosci.2020.106355.

Menezes E, Velho A, Santos F, Dinh T, Kaya A, Topper E, Moura A, Memili E. (2019) Uncovering Sperm metabolome to discover biomarkers for bull fertility. BMC Genomics. 20(1):714. doi:10.1186/s12864-019-6074-6.

Menezes ESB, Badial PR, El-Debaky H, Ulhusna A, Ugur MR, Kaya A, Topper E, Bulla C, Grant KE, Bolden-Tiller O, Moura AA, Memili E. (2019) Sperm miR-15a, miR-29b, miR-34a are associated with male fertility. doi: 10.1111/and.13412.

Mezera, M. A., C. S. Hamm, C. A. Gamarra, R. S. Gennari, A. B. Prata, R. Sartori, and M. C. Wiltbank. 2019. Profiles of prostaglandin F2alpha metabolite in dairy cattle during luteal regression and pregnancy: implications for corpus luteum maintenancedagger. Biol Reprod 101:76-90.

Monn, R. E., Mackey, J.C., Mayberry, K. J., Poole, R. K., Dudley, H., Alley, M., Poole, D. H. 2019. A two injection of Prostaglandin F2α pre-synchronization treatment decreases conception rates of developing replacement heifers. Translational Animal Science Volume 3, Issue 1, 1 January 2019, Pages 456–463, https://doi.org/10.1093/tas/txy136

Navarrete FA, Aguila L, Martin-Hidalgo D, Tourzani DA, Luque GM, Ardestani G, Garcia-Vazquez FA, Levin LR, Buck J, Darszon A, Buffone MG, Mager J, Fissore RA, Salicioni AM, Gervasi MG, Visconti PE. Transient Sperm Starvation Improves the Outcome of Assisted Reproductive Technologies. Front Cell Dev Biol. 2019 Nov 5;7:262. doi: 10.3389/fcell.2019.00262.

Negron-Perez VM, Fausnacht DW and Rhoads ML. Invited Review: Management strategies capable of improving the reproductive performance of heat-stressed dairy cattle. J Dairy Sci. 2019 Dec;102(12):10695-10710. doi: 10.3168/jds.2019-16718.

Niles, A. M., H. P. Fricke, P. D. Carvalho, M. C. Wiltbank, L. L. Hernandez, and P. M. Fricke. 2019. Effect of treatment with human chorionic gonadotropin 7 days after artificial insemination or at the time of embryo transfer on reproductive outcomes in nulliparous Holstein heifers. J Dairy Sci 102:2593-2606.

Ozbek M, Hitit M, Ergun E, Ergun L, Beyaz F, Erhan F, Yildirim N, Kandil B, Ozgenc O, Memili E. (2020). Expression Profile of Toll-Like Receptor 4 in Rat Testis and Epididymis throughout Postnatal Development. Andrologia. doi:10.1111/and.13518.

Pereira, M. H. C., M. C. Wiltbank, T. G. Guida, F. R. Lopes, Jr., B. I. Cappellozza, and J. L. M. Vasconcelos. 2020. Evaluation of presynchronization and addition of GnRH at the beginning of an estradiol/progesterone protocol on circulating progesterone and fertility of lactating dairy cows. Theriogenology 147:124-134.

Pillai VV, Kei TG, Reddy SE, Das M, Abratte C, Cheong SH and Selvaraj V. (2019). Induced pluripotent stem cell generation from bovine somatic cells indicates unmet needs for pluripotency sustenance. Animal Science Journal. 90(9):1149-1160.

Plewes MR, Hou X, Zhang P, Wood JR, Cupp AS, Lu X, Wang C, and Davis JS (2019) Yes-associated protein (YAP) is required for proliferation and function of bovine granulosa cells. Biol Reprod 101: 1001-1017, PMID: PMC6877782 

Poole D.H. 2019 Impacts of fescue toxicosis on the success of reproductive technologies. Proceedings in Applied Reproductive Strategies in Beef August 20-21, 2019

Poole RK, Womble CM, Poore MH, Poole DH, Pickworth CL. 2019 Effects of endophyte-infected tall fescue seed and protein supplementation on stocker steers: I. Growth performance and hemodynamic responses. J Anim Sci. 2019 Sep 3;97(9):3776-3785. doi: 10.1093/jas/skz249. PMID: 31359059

Poole RK, Brown AR, Poore MH, Pickworth CL, Poole DH. 2019 Effects of endophyte-infected tall fescue seed and protein supplementation on stocker steers: II. Adaptive and innate immune function. J Anim Sci. 2019 Oct 3;97(10):4160-4170. doi: 10.1093/jas/skz250. PMID: 31353402

Poole RK, Poole DH. 2019. Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species. Toxins (Basel). Jun 21;11(6):364. doi: 10.3390/toxins11060364. PMID: 31234268 Free PMC article. Invited Review.

Poole RK, Devine TL, Mayberry KJ, Eisemann JH, Poore MH, Long NM, Poole DH. 2019. Impact of slick hair trait on physiological and reproductive performance in beef heifers consuming ergot alkaloids from endophyte-infected tall fescue. J Anim Sci. Apr 3;97(4):1456-1467. doi: 10.1093/jas/skz024.

Ramirez, B.C., Xin, H., Halbur, P.G., Beermann, D.H., Hansen, S.L., Linhares, D.C.L., Peschel, J.M., Rademacher, C.J., Reecy, J.M., Ross, J.W., Shepherd, T.A., Koltes, J.E. 2019. At the intersection of industry, academia, and government: How do we facilitate productive precision livestock farming in practice? Animals (Basel) 9(9).

Rhoads ML. Effects of periconceptional heat stress on primiparous and multiparous daughters of Holstein dairy cows. Theriogenology. 2020 Mar 11. pii: S0093-691X(20)30181-3. doi: 10.1016/j.theriogenology.2020.03.015.

Rister AL, Bidne KL, Wood JR, and Dodds ED (2019) Microscale serum extraction method for the simultaneous analysis of corticosterone and lipids. Anal Methods, 11: 5746-5749, PMID: 32148562

Schalich KM, Herren A and Selvaraj V. (2020). Analysis of differential strategies to enhance detection of low-abundance protein in the bovine serum proteome. Animal Science Journal. Accepted, In press.

Schultz, R., Serao, N.L., Ross, J.W. 2019.  Genetic improvement of livestock, from conventional breeding to biotechnological approaches. In: Animal Agriculture: Sustainability, Challenges and Innovations. Eds. Bazer, F.W., Wu, G.  In Press (Elsevier). 

Seibert, J.T., Adur, M.K., Schultz, R.B., Thomas, P.Q., Kiefer, Z.E., Keating, A.F., Baumgard, L.H., Ross, J.W. 2019. Differentiating between the effects of heat stress and lipopolysaccharide on the porcine ovarian heat shock protein response. Journal of Animal Science. 97(12):4965-4973. 

Silveira, P. A. S., W. R. Butler, T. C. da Silva, C. C. Barros, M. N. Correa, and A. Schneider. Association of polymorphisms in the IGF-I, GHR, and STAT5A genes with serum IGF-I concentration and reproductive performance of Holstein dairy cows. Anim Reprod.Sci. 211(https://doi.org/10.1016/j.anireprosci.2019.106206):106206, 2019.

Snider AP and Wood JR (2019) Obesity induces ovarian inflammation and reduces oocyte quality. Reproduction 158: R79-R90, PMID: 30999278

Sun T and Diaz FJ. Ovulatory signals alter granulosa cell behavior through YAP1 signaling. Reproductive Biology and Endocrinology: (2019) 17 (1), 113.

Timme KR and Wood JR (2019) Use of single molecule fluorescent in situ hybridization (SM-FISH) to quantify and localize mRNAs in murine oocytes. J. Vis. Exp. 146, PMID: 31081819

Tenley SC, Spuri-Gomes R, Rosasco SL, Northrop EJ, Rich J, McNeel AK, Summers AF, Miles JR, Chase CC, Lents CA, Perry GA, Wood JR, Cupp AS, Cushman RA (2019) Maternal age influences the number of primordial follicles in the ovaries of yearling angus heifers, Animal Reproduction Science 200:105-112

Ugur MR, Dinh T, Hitit M, Kaya A, Topper E, Didion B, Memili E. (2020) Amino Acids of Seminal Plasma Associated with Freezability of Bull Sperm. Frontiers in Cell and Developmental Biology 7(347): 1-14.

Ugur MR, Saber Abdelrahman A, Evans HC, Gilmore AA, Hitit M, Arifiantini RI, Purwantara B, Kaya A, Memili E. (2019) Advances in cryopreservation of bull sperm. Front Vet Sci. doi: 10.3389/fvets.2019.00268.

Ugur MR, Kutchy NA, Menezes EBS, Ulhusna A, Haynes BP, Uzun A, Kaya A, Topper E, Moura AA, Memili E. (2019) Retained Acetylated Histone Four in Bull Sperm Associated with Fertility. Frontiers in Veterinary Science 6(23): 1-10.

Vailes MT, McCoski SR, Wooldridge LK, Reese ST, Pohler KG, Roper DA, Mercadante VR and Ealy AD. Post-transfer outcomes in cultured bovine embryos supplemented with epidermal growth factor, fibroblast growth factor 2, and insulin-like growth factor 1. Theriogenology. 2019 Jan 15;124:1-8. doi: 10.1016/j.theriogenology.2018.09.023.

Velho A, Wang H, Koenig L, Grant KE, Menezes E, Kaya A, Moura A, Memili E. (2019) Expression dynamics of Integrin Subunit Beta 5 in bovine gametes and embryos imply functions in male fertility and early embryonic development. Andrologia. 00:e13305. DOI: 10.1111/and.13305.

Wang L; Hand JM, Fu L, Smith GW and Yao J. 2019. DNA methylation and miRNA-1296 act in concert to mediate spatiotemporal expression of KPNA7 during bovine oocyte and early embryonic development. BMC Developmental Biology. 19 (1), 23. DOI: 10.1186/s12861-019-0204-x.

Wang J, Koganti PP and Yao J. 2020. Systematic identification of long intergenic non-coding RNAs expressed in bovine oocytes. Reproductive Biology and Endocrinology. 18(1) 13. DOI: 10.1186/s12958-020-00573-4.

Wooldridge LK and Ealy AD. Interleukin-6 increases inner cell mass numbers in bovine embryos. BMC Dev Biol. 2019 Feb 1;19(1):2. doi: 10.1186/s12861-019-0182-z.

Wooldridge LK and Ealy AD. Zinc Supplementation during in vitro bovine embryo culture increases inner cell mass and total cell numbers in bovine blastocysts. J. Anim. Sci. 2019; 97(12):4946-4950. doi: 10.1093/jas/skz351.

Wooldridge LK, Johnson SE and Ealy AD. Interleukin-6 requires JAK to stimulate inner cell mass expansion in bovine embryos. Reproduction. 2019 Oct;158(4):303-312. doi: 10.1530/REP-19-0286.

Zhang Z, Zhao LD, Johnson SE, Rhoads ML, Jiang H and Rhoads RP. Oxytocin is involved in steroid hormone-stimulated bovine satellite cell proliferation and differentiation in vitro. Domest Anim Endocrinol. 2019 Jan;66:1-13. doi: 10.1016/j.domaniend.2018.07.003.

 

Theses/Dissertations

Battista SEB, Garcia-Guerra A. Associations between morphometric characteristics of the reproductive tract and fertility in beef cattle. OSU MS thesis.

Heather L. Baldwin. Investigation of bovine conceptus galectins and the effect of bovine conceptus secretory proteins on the endometrial epithelial transcriptome. (MS Thesis)

Francesca Anastasia Gambonini, M.S. Effects of an Extruded Flaxseed Supplement on Transition Cow Milk Production and Reproductive Function and Effects of Early Pregnancy on Mediators of Immune Tolerance in Dairy Heifers. Master of Science Thesis. The Pennsylvania State University.

Lindsay F. Grose. The effect of bovine galectin-1, a conceptus secretory protein, on the endometrial transcriptome. (MS Thesis)

James Hester, PhD.  The impact of zinc deficiency during oogenesis, follicle assembly and growth.

Camilla Hughes, Phd. Molecular Changes in the Corpus Luteum During Maternal Recognition of Pregnancy. PhD Dissertation. The Pennsylvania State University

Shaina Jachter, B.S. 06/2020. Undergraduate Honor’s Thesis: “Effects of Kit-Ligand on Survival and Growth of Bovine Multilayer Follicles in Culture.” Honors Thesis Advisor C. Bishop.

Lundberg, Townson DH (2019) Investigation of Transforming Growth Factor-α and its potential role in promoting ovarian follicular dominance. UVM MS Thesis

Zackary K. Seekford (2020). Interleukin-6 Supplementation Improves Post-Transfer Embryonic and Early Fetal Development of In Vitro Produced Bovine Embryos (MS Thesis).

Wilson Simmons, M.S. 06/2020. Master’s Thesis: “Epidermal Growth Factor and Leukemia Inhibitory Factor Supplementation in Matrix-free, Three-Dimensional Bovine Follicle Culture.” Major Professor C. Bishop.

Lydia K. Wooldridge (2020). Supplementing Bovine Embryo Culture Media to Improve the Production and Quality of In Vitro Produced Bovine Embryos (PhD Dissertation). 

 

Active collaboration within the group

OSU and WI:  evaluated the effect of dose of GnRH at initiation of a 5-day synchronization protocol for FTET.

NY, PA, NH, VT and WV:  Samples collected to investigate associations between fertility outcomes and SNP in candidate genes from dairy cows.

PA and WV: Samples shared for analysis of molecular regulators of luteal function.

  

In addition to Hatch Multistate Funds, these studies were supported by:

Lee Rumberger and Family Endowment to JLP

CFAES Honors Will C. Hauk Endowment Grant – Undergraduate student - The Ohio State University

Iowa Pork Producers Association           

Iowa State University Bailey Career Development Award

John L. Pratt Animal Nutrition Program

NIH  

National Institute of Child Health and Human Development

National Institute of Environmental Health Science

National Institute of Food and Agriculture

National Pork Board

North Carolina Cattlemens Association Assessment

North Carolina Agricultural Foundation Inc.

OARDC SEEDS Early career investigator – The Ohio State University

OARDC SEEDS grant Competition – Graduate Student grant – The Ohio State University

OSU Agricultural Research Foundation

RTF funds from Dean to PI

RTF funds from PIs

Theriogenology Foundation Research Grant

USDA-NIFA-AFRI

Virginia Agricultural Council Research Funding

11/02/2021

Peer-reviewed journal articles reporting research from this project

Andrade JPN, Gomez-Leon VE, Andrade FS, Carvalho BP, Lacouth KL, Garcia FZ, Jacob JCF,Sales JNS, Wiltbank MC, Mello MRB. Development of a novel 21-day reinsemination program, ReBreed21, in Bos indicus heifers. Theriogenology 2020; 155:125-131.  10.1016/j.theriogenology.2020.04.021

Arbeithuber B, Hester J, Cremona MA, Stoler N, Higgins B, Anthony K, Chiaromonte F, Diaz FJ, Makova KD. Highly accurate mitochondrial DNA sequencing reveals age-dependent accumulation of mutations in germline and somatic mouse tissues. PLOS Biology (2020):18 (e3000745).

Bidne KL, Rister AL, McCain AR, Hitt BD, Dodds ED, and Wood JR. (2020) Maternal obesity alters placental lysophosphatidylcholine, lipid storage, and the expression of genes associated with lipid metabolism. Biol Reprod 104: 197-210, PMID: 33048132

Carr, S.N., Y. Jia, B. Crites, C. Hamilton, J.L. Edwards, J.C. Matthews and P.J. Bridges.  2020.  Form of supplemental selenium in vitamin-mineral premixes differentially affects early luteal and gestational concentrations of progesterone, and postpartum concentrations of prolactin in beef cows.  Animals.  10:1-11.

Chaney H. L., L. F. Grose, G. Charpigny, S. K. Behura, I. M. Sheldon, J. G. Cronin, T. E. Spencer, P. Lonergan, D. J. Mathew. Conceptus-induced, interferon tau dependent gene expression in bovine endometrial epithelial and stromal cells. Biol Reprod. 2020. 104:669-683. doi:10.1093/biolre/ioaa226.

Clark, K.L., Keating, A.F. 2020. Ataxia Telangiectasia Mutated coordinates the ovarian DNA repair and atresia-initiating response to phosphoramide mustard. Biology of Reproduction. 102(1):248-260.

Clark, K.L., Roach, C.M., Keating, A.F. 2020. Obesity alters ovarian DNA damage response and apoptotic proteins. Reproduction. 160(5): 751-760. 

Corredor, F.A., Pereira Sanglard, L., Leach, R.J., Ross, J.W., Keating, A.F., Serão, N.V.L. 2020. Genetic and genomic characterization of vulva size traits in Yorkshire and Landrace gilts. BMC Genetics. 21: 28. 

Domingues RR, Ginther OJ, Gomez-Leon VE, Wiltbank MC. Up-regulation of endometrial oxytocin receptor is associated with the timing of luteolysis in heifers with two and three follicular waves. Biol Reprod 2020; 102:316-326.  10.1093/biolre/ioz165

Domingues RR, Ginther OJ, Toledo MZ, Wiltbank MC. Increased dietary energy alters follicle dynamics and wave patterns in heifers. Reproduction 2020; 160:943-953.  10.1530/Rep-20-0362

Drum JN, Wiltbank MC, Monteiro PLJ, Prata AB, Gennari RS, Gamarra CA, Canavessi AMO, Sartori R. Oxytocin-induced prostaglandin F2-alpha release is low in early bovine pregnancy but increases during the second month of pregnancy. Biol Reprod 2020; 102:412-423.  10.1093/biolre/ioz169

Ealy AD, Speckhart SL, Wooldridge LK. Cytokines that serve as embryokines in cattle. Animals 2021, 11(8), 2313; https://doi.org/10.3390/ani11082313

Fontes PLP, Oosthuizen N, Ciriaco FM, Sanford CD, Canal LB, Cooke RF, Pohler KG, Henry DD, Mercadante VRG, Ealy AD, Johnson SE, DiLorenzo N, Lamb GC. Effects of nutrient restriction on the metabolic profile of Bos indicus-influenced and Bos taurus suckled beef cows. Animal. 2021 Mar;15(3):100166. doi: 10.1016/j.animal.2020.100166.

Ganesan, S., Keating, A.F. 2020. Ovarian mitochondrial and oxidative stress proteins are altered by glyphosate exposure in mice. Toxicology and Applied Pharmacology. 402:115116.

Ganesan, S., McGuire, B.C., Keating, A.F. 2020. Absence of glyphosate-induced effects on ovarian folliculogenesis and steroidogenesis. Reproductive Toxicology. 96:156-164.

Garcia-Guerra A, Sala RV, Carrenho-Sala L, Baez GM, Motta JCL, Fosado M, Moreno JF, Wiltbank MC. Postovulatory treatment with GnRH on day 5 reduces pregnancy loss in recipients receiving an in vitro produced expanded blastocyst. Theriogenology 2020; 141:202-210.  10.1016/j.theriogenology.2019.05.010 ** collaborative projects as part of NE1727 regional research project.

Garner TB, Carothers A, Hester JM and Diaz FJ. Role of zinc in female reproduction. Biology of Reproduction, 2021, 1–19 doi:10.1093/biolre/ioab023

Ginther, O.J., P. Nunes da Silva, V. E. Gomez-Le´on, R. R. Domingues and E.K. Inskeep. 2021. Side of ovulation at each end of two- and three-wave interovulatory intervals and before and after pregnancy in cattle. Anim. Reprod. Sci. 229:154-163.

Gomez-Leon VE, Andrade JP, Kirkpatrick BW, Moghbeli SM, Garcia-Guerra A, Ginther OJ, Wiltbank MC. Selection of fewer dominant follicles in Trio carriers given GnRH antagonist and LH action replaced by nonpulsatile hCG. Biol Reprod 2020.  10.1093/biolre/ioaa167 **collaborative projects as part of NE1727 regional research project.

 Gomez-Leon VE, Andrade JP, Kirkpatrick BW, Molaei S, Garcia-Guerra A, Ginther OJ, Wiltbank MC. 2020. Selection of fewer dominant follicles in Trio carriers given GnRH antagonist and LH action replaced by nonpulsatile hCG. Biology of Reproduction, 103: 1217-1228.** collaborative projects as part of NE1727

Gomez-Leon VE, Ginther OJ, Domingues RR, Guimaraes JD, Wiltbank MC. Necessity for LH in selection and continued growth of the bovine dominant follicle. Reproduction 2020; 159:559-569.  10.1530/Rep-19-0342

Gomez-Leon VE, Ginther OJ, Guimaraes JD, Wiltbank MC. Hormonal mechanisms regulating follicular wave dynamics II: Progesterone decreases diameter at follicle selection regardless of whether circulating FSH or LH are decreased or elevated. Theriogenology 2020; 143:148-156.  10.1016/j.theriogenology.2019.11.003

Graves, K.L., Mordhorst, B.R., Wright, E.C., Hale, B.J., Stalder, K.J., Keating, A.F., Ross J.W. 2020. Identification of measures predictive of age of puberty onset in gilts. Translational Animal Science 4: 285-292. 

Habeeb, H., Kleditz, L., Hazzard, T. M., Bishop, C. V., Ramsey, A., Stormshak, F., Kutzler, M. A. Endometrial estrogen receptor, follicle stimulating hormone receptor, and mucin-1 expression during early diestrus in ewes following PG-600 administration. Veterinary medicine and Science. Under Review, Revised August 2021.

Hughes CHK, Inskeep EK, Pate JL. 2020. Temporal changes in the corpus luteum during early pregnancy reveal regulation of pathways that enhance steroidogenesis and suppress luteolytic mechanisms. Biology of Reproduction, ioaa047, https://doi.org/10.1093/biolre/ioaa047

Hughes, C. H. K., A. Rogus, E. K Inskeep and J. L Pate. 2021. NR5A2 and potential regulatory miRNAs in the bovine CL during early pregnancy. Reproduction. 161:173-182. DOI:  10.1530/REP-20-0009.

Jachter, S. L., Simmons, W.P., Estill, C., Xu, J., Bishop, C. V. Matrix-free three-dimensional culture of bovine secondary follicles to antral stage: Impact of media formulation and epidermal growth factor (EGF). Theriogenology. Under review July 2021.

Jaques JT, Cardoso RC, Chachere J, Sinha S, Seery R, Wilkes AA, Forrest D, Looney CR. Using Anti-Müllerian Hormone (AMH) as a Predictor of Ova Production for Bovine Embryo Transfer. Advances in Reproductive Sciences, 8 (1): 1-12, 2020.

Kott ML, Pancini S, Speckhart SL, Kimble LN, White RR, Stewart JL, Johnson SE, Ealy AD. Effects of mid-gestational L-citrulline supplementation to twin-bearing ewes on umbilical blood flow, placental development and lamb production traits. Transl Anim Sci. 2021 Jun 9;5(3):txab102. doi: 10.1093/tas/txab102.

Madureira G, Consentini CEC, Motta JCL, Drum JN, Prata AB, Monteiro PLJ, Melo LF, Goncalves JRS, Wiltbank MC, Sartori R. Progesterone-based timed AI protocols for Bos indicus cattle II: Reproductive outcomes of either EB or GnRH-type protocol, using or not GnRH at AI. Theriogenology 2020; 145:86-93.  10.1016/j.theriogenology.2020.01.033

Madureira G, Gomez-Leon V, Grillo GF, Nascimento Andrade JP, Lett B, Moghbeli SM, Wiltbank MC, Kirkpatrick BW. Practical application of an impractical bovine genotype: creating bilateral twin pregnancies in Trio allele carriers. J Anim Sci 2020; 98.  10.1093/jas/skaa292

Madureira G, Motta JCL, Drum JN, Consentini CEC, Prata AB, Monteiro PLJ, Melo LF, Alvarenga AB, Wiltbank MC, Sartori R. Progesterone-based timed AI protocols for Bos indicus cattle I: Evaluation of ovarian function. Theriogenology 2020; 145:126-137.  10.1016/j.theriogenology.2020.01.030

Masello M., M. M. Perez, G. E. Granados, M. L. Stangaferro, B. Ceglowski, M. J. Thomas, and J. O. Giordano*. 2020. Effect of reproductive management programs for first service on replacement dairy heifer economics. J. Dairy Sci. 104:471-485.

Masello M., Y. Ren, D. Erickson, and J. O. Giordano*. 2020. An automated controlled-release device for intravaginal hormone delivery. J. Dairy Sci. Comm. 1:15-20. DOI: https://doi.org/10.3168/jdsc.2020-18816 

Mathew, D.J. Commentary Glucose and fructose transport across the epithelialchorial placenta: SLC2A and the uterine-placental interface in pigs. Endocrinology. 2020. 161:1-2. Doi:10.1210/endocr/bqaa138.

Maucieri AM, Townson DH (2021) Evidence and manipulation of O-GlcNAcylation in granulosa cells of bovine antral follicles. Biol Reprod 104(4): 914-923

Mayorga E.J., Ross, J.W., Keating, A.F., Rhoads, R.P. Baumgard, L.H. 2020. Biology of heat stress; the nexus between intestinal hyperpermeability and reproduction in swine.  Theriogenology. 154:73-83.

Menichetti B.T., Piñeiro J.M., Barragan A. A., Relling A., Garcia-Guerra A., G.M. Schuenemann. 2020. Association of prepartum lying time with nonesterified fatty acids and stillbirth in prepartum dairy heifers and cows. Journal of Dairy Science, 103: 11782-11794.

Mezera MA, Li W, Edwards AJ, Koch DJ, Beard AD, Wiltbank MC. Identification of stable genes in the corpus luteum of lactating Holstein cows in pregnancy and luteolysis: Implications for selection of reverse-transcription quantitative PCR reference genes. J Dairy Sci 2020; 103:4846-4857.  10.3168/jds.2019-17526

Mogollon HDG, Ferrazza RA, Vallejo VH, Destro FC, Ochoa JC, Nogueira C, Carvalho RF, Moraes LN, Rizzoto G, Sartori R, Wiltbank MC, Ferreira JCP. Short communication: Heat stress does not affect induced luteolysis in Holstein cows. J Dairy Sci 2020; 103:5629-5633.  10.3168/jds.2019-17452

Moorey, S.E., B.N. Walker, M.F. Elmore, J.B. Elmore, S.P. Rodning, and F.H. Biase. Rewiring of gene expression in circulating white blood cells is associated with pregnancy outcome in heifers (Bos taurus). Scientific Reports. 2020. 10(1):16786. doi: 10.1038/s41598-020-73694-w.

Moorey, S.E., F.H. Biase. Beef Heifer Fertility: Importance of Management Practices and Technological Advancements. Journal of Animal Science and Biotechnology. 2020. 11:97 doi: 10.1186/s40104-020-00503-9.

Moorey, S.E., J.M. Monnig, M.F. Smith, M.S. Ortega, J.A. Green, K.G. Pohler, G.A. Bridges, S.K. Behura, T.W. Geary. Differential transcript profiles in cumulus-oocyte complexes originating from pre-ovulatory follicles of varied physiological maturity in beef cows. Genes. 2021. 12(6), 893. doi: https://doi.org/10.3390/genes12060893.

Motta JCL, Madureira G, Silva LO, Alves R, Silvestri M, Drum JN, Consentini CEC, Prata AB, Pohler KG, Wiltbank MC, Sartori R. Interactions of circulating estradiol and progesterone on changes in endometrial area and pituitary responsiveness to GnRH. Biol Reprod 2020; 103:643-653.  10.1093/biolre/ioaa065

Nafziger S, Tenley S, Summers AF, Abedal-Majed MA, Hart M, Bergman J, Kurz SG, Davis JS, Wood JR, Cupps AS (2020). Attainment and maintenance of pubertal cyclicity may predict reproductive longevity in beef heifers. Biol Reprod in press, PMID: 33709137

Ott, TL. Immunological detection of pregnancy: Evidence for systemic immune modulation during early pregnancy in ruminants. 2020 Theriogenology 150, 498-503.

Owens CE, Daniels KM, Ealy AD, Knowlton KF, Cockrum RR. Graduate student literature review: Potential mechanisms of interaction between bacteria and the reproductive tract of dairy cattle. J Dairy Sci. 2020 Nov;103(11):10951-10960. doi: 10.3168/jds.2019-18050.

Owens CE, Huffard HG, Nin-Velez AI, Duncan J, Teets CL, Daniels KM, Ealy AD, James RE, Knowlton KF, Cockrum RR. Microbiomes of various maternal body systems are predictive of calf digestive bacterial ecology. Animals 2021, 11(8), 2210; https://doi.org/10.3390/ani11082210

Padmanabhan V, Cardoso RC. Neuroendocrine, Autocrine, and Paracrine Control of Follicle-Stimulating Hormone Secretion. Molecular and Cellular Endocrinology, 500: 1-9, 2020.

Pate JL. 2020. Roadmap to pregnancy during the period of maternal recognition in the cow: Changes within the corpus luteum associated with luteal rescue, Theriogenology, https://doi.org/10.1016/j.theriogenology.2020.01.074

Pereira MHC, Wiltbank MC, Guida TG, Lopes FR, Cappellozza BI, Vasconcelos JLM. Evaluation of presynchronization and addition of GnRH at the beginning of an estradiol/progesterone protocol on circulating progesterone and fertility of lactating dairy cows. Theriogenology 2020; 147:124-134.  10.1016/j.theriogenology.2019.11.025

Pérez M. M., R. Wijma, M. Scarbolo, E. Cabrera, F. Sosa, E. M. Sitko, and J. O. Giordano*. 2020. Lactating dairy cows managed for second and greater AI services with the Short-Resynch or day 25 Resynch program had similar reproductive performance. J. Dairy Sci. 103:10769-10783. DOI: 10.3168/jds.2020-18607   

Plewes MR, Hou X, Talbott H, Zhang P, Wood JR, Cupp AS, and Davis JS. (2020) Luteinizing hormone regulates the phosphorylation and localization of the mitochondrial effector dynamin like 1 (DRP1) and steroidogenesis in the bovine corpus luteum. FASEB J, 32:5299-5316, PMID: 32077149

Plewes MR, Krause C, Talbott HA, Przygrodzka E, Wood JR, Cupp AS, and Davis JS. (2020) Trafficking of cholesterol from lipid droplets to mitochondria in bovine luteal cells: acute control of progesterone synthesis. FASEB J, 34: 10731-10750, PMID 32077149

Prata AB, Madureira G, Robl AJ, Ribeiro HS, Sagae M, Elias MCV, Pimenta C, Barrios J, Hartmman D, Schneider AA, Sandoval GAF, Wiltbank MC, et al. Progesterone-based timed AI protocols for Bos indicus cattle III: Comparison of protocol lengths. Theriogenology 2020; 152:29-35.  10.1016/j.theriogenology.2020.04.020

Rhoads ML. Effects of periconceptional heat stress on primiparous and multiparous daughters of Holstein dairy cows. Theriogenology. 2020 Mar 11. pii: S0093-691X(20)30181-3. doi: 10.1016/j.theriogenology.2020.03.015.

Romoser, M.R., Hale, B.J., Seibert, J.T., Gall, T., Rademacher, C.J., Stalder, K.J., Baumgard, L.H., Keating, A.F., Ross J.W. 2020. Methods for reproductive tract scoring as a tool for improving sow productivity. Translational Animal Science. 4 (1): 275–284.

 Sala RV, Melo LF, Motta JCL, Leffers-Neto L, Carrenho-Sala L, Fosado M, Moreno JF, Baruselli PS, Wiltbank MC, Garcia-Guerra A. 2020 Optimization of a 5-day fixed-time embryo transfer (FTET) protocol in heifers I. Manipulation of circulating progesterone through reutilization of intravaginal progesterone devices during FTET. Theriogenology, 156: 171-180.** collaborative projects as part of NE1727

Sala RV, Melo LF, Motta JCL, Leffers-Neto L, Carrenho-Sala LC, Fosado M, Moreno JF, Baruselli PS, Wiltbank MC, Garcia-Guerra A. Optimization of a 5-day fixed-time embryo transfer (FTET) protocol in heifers I. Manipulation of circulating progesterone through reutilization of intravaginal progesterone devices during FTET. Theriogenology 2020; 156:171-180.  10.1016/j.theriogenology.2020.06.002  ** collaborative projects as part of NE1727 regional research project.

Schilkowsky E. M., G. E. Granados, E M. Sitko, M. Masello, M. M. Perez, J. O. Giordano*. 2021. Evaluation and characterization of estrus alerts and behavioral parameters generated by an ear-attached accelerometer-based system for automated detection of estrus. J. Dairy Sci. 104:6222-6237. https://doi.org/10.3168/jds.2020-19667

Seekford ZK, Wooldridge LK, Dias NW, Timlin CL, Sales AF, Speckhart SL, Pohler KG, Cockrum RR, Mercadante VGR, Ealy AD. Interleukin-6 supplementation improves post-transfer embryonic and fetal development of in vitro-produced bovine embryos. Theriogenology. 2021 Aug;170:15-22. doi: 10.1016/j.theriogenology.2021.04.004. Epub 2021 Apr 28.

Stangaferro M.L., Toledo M.Z., Gennari R.S., Perez M.M., Gamarra C.A., Sitko E.M., Monteiro P.L.J. Jr, Masello M., Prata A.B., Granados G.E., Van Amburgh M.E., Luchini D., Shaver R.D., Wiltbank M.C., Giordano J.O. 2021. Effects of feeding rumen-protected methionine pre- and postpartum on reproductive outcomes of multiparous Holstein cows. J. Dairy Sci. 104:11210-11225. https://doi.org/10.3168/jds.2021-20190 **Collaborative projects as part of NE1727 regional research project.

Talbott HA, Plewes MR, Krause C, Xiaoying H, Zhang P, Rizzo WB, Wood JR, Cupp AS, and Davis JS. (2020) Formation and characterization of lipid droplets of the bovine corpus luteum. Scientific Reports 10: 11287, PMID 32647143

Timlin CL, Lynn A, Wooldridge LK, Uh K, Ealy AD, White RR, Lee K, Mercadante VRG. Physical parameters of bovine activated oocytes and zygotes as predictors of development success. Zygote. 2021 Mar 19:1-7. doi: 10.1017/S0967199421000058.

Toledo M. Z., M. L. Stangaferro, R. S. Gennari, R. V. Barletta, M. M. Perez, R. Wijma, E. M. Sitko, G. Granados, M. Masello, M. E. Van Amburgh, D. Luchini, J. O. Giordano, R. D. Shaver, and M. C. Wiltbank. 2021. Effects of feeding rumen-protected methionine pre- and postpartum in multiparous Holstein cows: Lactation performance and plasma amino acid concentrations. J. Dairy Sci. 104:7583-7603. https://doi.org/10.3168/jds.2020-19021**Collaborative projects as part of NE1727 regional research project.

Vanselow J, Christenson LK and Pate JL. 2020. Editorial: Regulation of Dynamic Changes and Remodeling Events During the Formation, Rescue and Regression of the Corpus Luteum. Front. Endocrinol. 11:244. doi: 10.3389/fendo.2020.00244

Wooldridge LK, Ealy AD. Interleukin-6 promotes primitive endoderm development in bovine blastocysts. BMC Dev Biol. 2021 Jan 12;21(1):3. doi: 10.1186/s12861-020-00235-z.

Zhang M, Chaney HL, Current JZ and Yao J. 2021. Identification of the core promoter of ZNFO, an oocyte-specific maternal effect gene in cattle. Gene. https://doi.org/10.1016/j.gene.2021.145717.

 Abstracts for scientific conferences

Arneson JW, Stewart JW, Harrod MK, Newberne HM, Burgess MK, Jordan JA, White RR, Ealy AD, El-Kadi SW, Rhoads RP, Rhoads ML. Impact of heat stress and glycemic state on plasma gamma-aminobutyric acid (GABA) in lactating Holstein cows. 2021 J Dairy Sci 104: Suppl 1.

B. Duran, R. V. Sala, P. L. J. Monteiro, C. Gamarra, M. Fosado, E. Walleser, A. Prata, R. Gennari, J. Moreno, M. Wiltbank, A. García-Guerra. 2020.“Treatment with gonadotrophin-releasing hormone on Day 7 or 21 does not reduce pregnancy loss in dairy heifers receiving in vitro-produced embryos”. Reproduction, Fertility and Development, 2019, Vol. 32 No. 2 Page 176-177.

B. T. Menichetti, A. Garcia-Guerra, J. Lakritz, W. P. Weiss, J. S. Velez, D. Merchan, G. M. Schuenemann. 2020. “Effect of timing of prepartum vaccination relative to pen change of dairy cows on lying time and serum glucose, nonesterified fatty acids, and calcium at calving”. Journal of Dairy Science 2020, Vol 103, Suppl 1, Page 175.

 B. T. Menichetti, J. M. Piñeiro, A. Garcia-Guerra, A. E. Relling, W. P. Weiss, G. M. Schuenemann. 2020. “Consistency of lying time is associated with reduced serum nonesterified fatty acids of prepartum dairy heifers and cows”. Journal of Dairy Science 2020, Vol 103, Suppl 1, Page 174.

 B.R. Crites, S.N. Carr, C. Hamilton, J.C. Matthews, W.R. Burris and P.J. Bridges.  2020.  Form of dietary selenium affects cholesterol biosynthesis and immune response elements in the early luteal phase bovine corpus luteum.  Special Issue, Proc. of the 53rd annual meeting of the Soc. for the Study of Reproduction.

Baldwin H, Zhang M, Current J and Yao J. Expression profile of ovarian agouti-signaling protein in cattle. 47th Annual Conference of the IETS Virtual Conference. January 18-21, 2021. (Abstract).

Bidne KL, Rister AL, Dodds ED, and Wood JR (2020) Maternal western diet consumption alters placental lipid composition and apolipoprotein gene expression. 53rd Annual Meeting of the Society for the Study of Reproduction, Virtual; selected for pre-doctoral platform competition

Bishop C.V., Simmons W.P., Jachter S.L., De Souza V.P., Xu J., Estill C. Epidermal Growth Factor (EGF) and EGF+ Kit Ligand or Leukemia Inhibitory Factor Enhances Survival and Growth of Bovine Multilayer Follicles in 3D Matrix-free Culture System. Society for the Study of Reproduction July 2020, Virtual Poster Presentation.

Bochantin KA, Keane JA, Snider AP, Kurz SG, Bergman JW, McFee RM, Cupp AS, and Wood JR (2020) Systemic inflammation in beef cows is associated with delayed puberty attainment and decreased production in small follicles. 53rd Annual Meeting of the Society for the Study of Reproduction, Virtual

Bries, A., Webb, J., Vogel, B., Carrillo, C., Keating, A., Schalinske, K. 2020. Letrozole-induced polycystic ovary syndrome attenuates cystathionine-b synthase gene expression in the ovaries of female Sprague Dawley rats. Current Developments in Nutrition. 4: Suppl 2; 1244.

Butler, H. Butler, E. Etcheverry, J. F. Pagani, R. Alberio, A. García-Guerra. 2020. “Treatment with gonadotrophin releasing hormone at the time of AI in beef heifers that fail to express oestrus after an estradiol-based synchronization protocol improves pregnancies per AI”. Reproduction, Fertility and Development, 2019, Vol. 32 No. 2 Page 208-208.

Current J, Baldwin H, Zhang M and Yao J. Differential gene expression of bovine long noncoding RNAs in single oocytes aspirated from small and large follicles. 47th Annual Conference of the IETS Virtual Conference. January 18-21, 2021. (Abstract).

D. Pereira, D. Moreno, R. Sala, L. Carrenho-Sala, M. Fosado, J. Moreno, A. García-Guerra. 2020. “SOFaaci-HEPES or holding media can be used for embryo loading without changes in pregnancies per embryo transfer nor pregnancy loss in an in vitro-produced embryo transfer program”. Reproduction, Fertility and Development, 2019, Vol. 32 No. 2 Page 178-178.

de Souza V.P., Jensen J., Estill C., Bishop C. V. Increasing vitamin D levels to improve fertilization rates in cattle. Abstract Submitted for Poster Presentation to the Western Section American Society of Animal Science 2021 Meeting, October 17-20, Fort Collins, CO.

E. Rojas Canadas, S. E. Battista, J. Kieffer, S. Wellert, A. García-Guerra. 2020. “Increasing gonadotrophin-releasing hormone dose at initiation of a 5-day CO-Synch protocol increases ovulatory response but not fertility in yearling beef heifers”. Reproduction, Fertility and Development, 2019, Vol. 32 No. 2 Page 206-207.

Ermisch AF, Bidne KL, and Wood JR (2020) Increased adiposity and circulating glucose promote pro-inflammatory and immune cell signaling in the cumulus oocyte complex of TLR4-hyporesponsive mice fed a high fat/high sugar diet. 53rd Annual Meeting of the Society for the Study of Reproduction, Virtual

González Alvarez, M.E., McGuire, B.C., Keating, A.F. 2020. Effects of zearalenone exposure on the ovarian proteome in lean and obese mice. *Accepted to Gordon Research Conference on Environmental Endocrine Disrupting Chemicals. Meeting cancelled due to COVID19.

González Alvarez, M.E., McGuire, B.C., Keating, A.F. 2020. Investigating additive impact of obesity on zearalenone-induced ovotoxicity. Society of Toxicology annual meeting. *Meeting cancelled due to COVID19.

González Alvarez, M.E., McGuire, B.C., Keating, A.F. 2020. Ovarian effects of perfluorooctanoic acid exposure in lean and obese mice. Society for the Study of Reproduction annual meeting.

Goulet M, Hutchings D, Elder D, Tsang PCW.  2021. Regulation of Cellular Communication Network Factor 1 by Ras Homolog Family Member A in Bovine Luteal Cells. 55th Annual Meeting of the Society for the Study of Reproduction, Saint Louis, Missouri (held Dec 15 – Dec 18 due to COVID-19; hybrid mode of presentation).

Granados G. E., M.M Pérez, and J. O. Giordano*. 2020. Pattern of Behavioral, Physiological, and Performance Parameters before Insemination in Dairy Cows that Become Pregnant or Not to First Service.  J. Dairy Sci. Volume 103. E-Supplement 1.

Gurung S, Koganti PP, Schalich KS, and Selvaraj V. Absence of evidence for physiological fetal microchimerism across the epitheliochorial bovine placental interface

Hessock, E.A., M.F. Smith, T.W. Geary, K.G. Pohler, J.A. Green, S.K. Behura, A.K. Stokes, and S.E. Moorey. Transcriptome profiles of in vivo matured bovine cumulus-oocyte complexes reveal unique gene expression between the oocyte and cumulus cells. 54th Annual Meeting of the Society for the Study of Reproduction (SSR), St Louis, MO.

Horn, E.J., C.C. Read, J.L. Edwards, F.N. Schrick, J.D. Rhinehart, R.R. Payton, S.R. Campagna, H.F. Castro, J.L. Klabnik, and S.E. Moorey. Pre-ovulatory follicular fluid and serum metabolome profiles in beef cows with thin, moderate, and obese body condition. 54th Annual Meeting of the Society for the Study of Reproduction (SSR), St Louis, MO.

K. Nickles, A. E. Relling, A. Garcia-Guerra, F. L. Fluharty, A. J. Parker. 2020. “Cows housed in muddy environmental conditions during late gestation have lesser body weight and body condition score compared with cows housed on wood chips”. Journal of Animal Science, Volume 98, Issue Supplement 4, November 2020, Page 48.

Keane JA, Nafziger SR, Bergman JW, Kurz SG, Snider AP, Bochantin KA, Wood JR, Cushman RA, Summers AF, and Cupp AS (2020) Environmental parameters may increase likelihood of beef heifers classified with earlier or later pubertal attainment. 53rd Annual Meeting of the Society for the Study of Reproduction, Virtual

Lupicka, M., JL Pate. 2020. MiR-1246 is the most abundant miRNA in luteal extracellular vesicles and it regulates T cell transcripts associated with their activation. Society for the Study of Reproduction (virtual poster session).

L. Carrenho-Sala, M. Fosado, R. Sala, E. Peralta, D. Pereira, D. Moreno, J. Moreno, A. García-Guerra. 2020. “Synchronization of follicle wave emergence prior to superstimulation with purified FSH for ovum pickup affects blastocyst rate in pregnant Holstein heifers”. Reproduction, Fertility and Development, 2019, Vol. 32 No. 2 Page 215-216.

Masello M., M. M. Perez, G. E. Granados, M. L. Stangaferro, B. Ceglowski, M. J. Thomas, and J. O. Giordano*. 2020. Reduced age at first calving improved the economic performance of replacement dairy heifers.  J. Dairy Sci. Volume 103. E-Supplement 1.

Masello M., Y. Ren, D. Erickson, and J. O. Giordano*. 2020. An electronically-controlled intravaginal hormone delivery device successfully induced luteal regression in dairy cattle.  J. Dairy Sci. Volume 103. E-Supplement 1.

Mathew, D.J., H.L. Chaney, L.F. Grose, G. Charpigny, S.K. Behura, I.M. Sheldon, J.G. Cronin, T.E. Spencer, and P. Lonergan. Effect of galectin-1 on bovine endometrial epithelial and fibroblast cell transcriptomes in 3D cell culture. 54th Annual Meeting of the Society for the Study of Reproduction (SSR), St Louis, MO.

Maucieri AM, Townson DH (2021) Evaluating the impact of the hexosamine biosynthesis pathway and O-GlcNAcylation on glucose metabolism in bovine granulosa cells. Society for the Study of Reproduction Annual Meeting. St. Louis, MO.

McGuire, B.C., Ganesan, S., Keating, A.F. 2020. Impact of Glyphosate exposure on the neonatal ovarian proteome. *Accepted to Gordon Research Conference on Environmental Endocrine Disrupting Chemicals. Meeting cancelled due to COVID19.

McGuire, B.C., González Alvarez, M.E., Keating, A.F. 2020. Determining impacts of glyphosate exposure on ovarian function in lean and obese mice. Society of Toxicology annual meeting. *Meeting cancelled due to COVID19.

McGuire, B.C., González Alvarez, M.E., Keating, A.F. 2020. Exposure to glyphosate alters the ovarian proteome with differential effects in lean and obese mice. Society for the Study of Reproduction annual meeting.

Mezera MA, Hughes CHK, Pate JL, Wiltbank MC. 2020. The impact of pregnancy on the transcriptome of the bovine CL: insights from combining two independent experiments.  Society for the Study of Reproduction (virtual poster session).

Novbotova, G., Ganesan, S., McGuire, B.C., Keating, A.F. 2020. Maternal and ovarian impacts of chronic glyphosate exposure. Society for the Study of Reproduction annual meeting.

Oliver, M.A., K.D. Peterson, S. Bhandari and D.J. Mathew. Effect of progesterone on bovine endometrial cell expression of select transporters and growth factors. American Dairy Science Association 2021 Annual meeting. Virtual.

Oliver, M.A., K.D. Peterson, S. Bhandari, R.R. Payton, L.G. Schneider, J.L. Edwards, and D.J. Mathew. The effect of endometrial cell conditioned media on in vitro cultured bovine embryo development. 54th Annual Meeting of the Society for the Study of Reproduction (SSR), St Louis, MO.

Peterson, K.D., M.A. Oliver, S. Bhandari, S.E. Moorey, and D.J. Mathew. 2021. The effect of small and large ovarian follicle fluid on oviduct cell gene expression in cattle. American Dairy Science Association 2021 Annual meeting. Virtual.

R. Sala, L. Carrenho-Sala, V. Absalon-Medina, A. Lopez, M. Fosado, J. Moreno, M. Wiltbank, A. García-Guerra. 2020. “Optimization of a five-day fixed-time embryo transfer program in dairy heifers: Use of gonadotrophin-releasing hormone at initiation of the protocol”. Reproduction, Fertility and Development, 2019, Vol. 32 No. 2 Page 179-179.

Read, C.C., J.L. Edwards, F.N. Schrick, J.D. Rhinehart, R.R. Payton, S.R. Campagna, H.F. Castro, J.L. Klabnik, and S.E. Moorey. Influence of pre-ovulatory follicle size on the follicular fluid metabolome in lactating beef cows. 54th Annual Meeting of the Society for the Study of Reproduction (SSR), St Louis, MO.

Rishi, J.K., Roach, C.M., Baumgard, L.H., Ross, J.W., Keating, A.F. 2020. Impact of heat stress on ovarian chemical biotransformation enzyme abundance. Society of Toxicology annual meeting. *Meeting cancelled due to COVID19.

Roach, C.M., Clark, K.L., Keating, A.F. 2020. Examining the effects of obesity on circulating prolactin and the ovarian proteome in hyperphagia-induced obese mice. Society for the Study of Reproduction annual meeting.

Roach, C.M., Mayorga, E.J., Ross, J.W., Baumgard, L.H., Keating, A.F. 2020. Zearalenone alters physiological function in heat-stressed prepubertal gilts. *Accepted to Gordon Research Conference on Environmental Endocrine Disrupting Chemicals. Meeting cancelled due to COVID19.

Roach, C.M., Mayorga, E.J., Ross, J.W., Baumgard, L.H., Keating, A.F. 2020. Heat stress alters reproductive phenotypic impacts of Zearalenone in pre-pubertal gilts. MidWest American Society of Animal Science meeting.

S. R. Wellert, S. E. Battista, J. Kieffer, R. N. Lurch, A. García-Guerra. 2020. “Comparison of different Doppler ultrasound settings for pregnancy diagnosis based on corpus luteum perfusion at 21 days after AI in beef cattle”. Reproduction, Fertility and Development, 2019, Vol. 32 No. 2 Page 211-211.

S.N. Carr, B.R. Crites, Y. Jia, C. Hamilton, J.C. Matthews and P.J. Bridges.  2020.  Form of supplemental selenium affects steroidogenesis by the early luteal phase corpus luteum in beef cattle.  Special Issue, Proc. of the 53rd annual meeting of the Soc. for the Study of Reproduction.

Schalich KM, Koganti PP, Herren A, Castillo J, Reiff O, Cheong S, and Selvaraj V. (2020). Enhanced resolution and direct profiling of bovine uterine fluid secretions through data-independent acquisition (DIA) in mass-spectrometry based proteomics.

Schilkowsky E. M., G. E. Granados, E M. Sitko, M. Masello, M. M. Perez, and J.O. Giordano*. 2020. Evaluation and characterization of estrus alerts from an ear-attached accelerometer-based automated estrus detection system.  J. Dairy Sci. Volume 103. E-Supplement 1.

Sitko E. M., M.M. Pérez, G.E. Granados, M. Masello, and J.O. Giordano*. 2020. Age at first calving affected reproductive performance of primiparous cows managed with a program that favored timed artificial insemination. J. Dairy Sci. Volume 103. E-Supplement 1.

Sitko E.M., M.M. Pérez, G.E. Granados, M. Masello, and J.O. Giordano*. 2020. Association between age at first calving and reproductive performance of primiparous cows managed with a program that favored insemination at detected estrus. J. Dairy Sci. Volume 103. E-Supplement 1.

Snider AP, Gomes RS, Summers AF, Abedal-Majed MA, Tenley SC, Wood JR, Davis JS, and Cupp AS (2020) Lipids involved in pro- and anti-inflammatory responses are altered in follicular fluid and plasma of cows administered a low-dose-FSH protocol and may be used as markers of ovulation in beef cows. 53rd Annual Meeting of the Society for the Study of Reproduction, Virtual; selected for post-doctoral poster competition

Stangaferro M. L., J. O. Giordano*, M. Z. Toledo, and M. C. Wiltbank. 2020. Prediction of pregnancy probability at first service in multiparous dairy cows based on early lactation data.  J. Dairy Sci. Volume 103. E-Supplement 1. **Collaborative projects as part of NE1727 regional research project.

Stewart J, Newberne H, Arneson A, Harrod M, Negron-Perez V, Haines H, Jordan J, White R, Ealy A, El-Kadi S, Rhoads R and Rhoads M. Glucose infusion during heat stress restores normoglycemia but does not improve milk production. 2020. J. Dairy Sci. Vol. 103, Suppl. 1. 148.

Stewart JW, Newberne HM, Harrod MK, Arneson AG, Negron-Perez VM, White RR, Ealy AD, El-Kadi SW, Rhoads RP, Rhoads ML. Heat stress and glycemic state alter milk production and composition in Holstein dairy cows. 2021 American Dairy Science Association Annual Meeting, 2021 J Dairy Sci 104: Suppl 1.

Studer, J.M., Kiefer, Z.E., Keating, A.F., Baumgard, L.H., Olsen, K.M., Rambo, Z., Wilson, M.E., Rapp, C., Ross, J.W. 2020. Influence of dietary manganese supplementation on transcript and protein abundance in the corpus luteum of swine. Society for the Study of Reproduction annual meeting.

Toledo M. Z., M. L. Stangaferro, R. S. Gennari, P. L. J. Monteiro Jr., M. M. Perez, M. Masello, M. E. Van Amburgh, D. Luchini, R. D. Shaver, J. O. Giordano, M. C. Wiltbank. 2020. Effect of feeding rumen-protected methionine pre- and postpartum on health, herd exit dynamics and time to pregnancy in multiparous dairy cows.  J. Dairy Sci. Volume 103. E-Supplement 1. **Collaborative projects as part of NE1727 regional research project.

Torres-Gonzalez E, Arbeithuber B, Hester J, Cremona M, Stoler N, Higgins B, Anthony K, Chiaromonte F, Diaz F, and Makova K.  Duplex sequencing uncovers age-related increase in the frequency of de novo indels in mouse mitochondrial DNA. Society for Molecular Biology and Evolution Annual Meeting. Quebec City, CA, June 28th- July 2nd, 2020.

Zhang M, Baldwin H, Current J and Yao J. Characterization of the promoter region of ZNFO, an oocyte-specific gene in cattle. 47th Annual Conference of the IETS Virtual Conference. January 18-21, 2021. (Abstract).

Theses/Dissertations

Alicia Arneson (2021) Evaluating the impact of heat stress and altered glycemic state on plasma ɣ-Aminobutyric Acid (GABA) in lactating Holstein cows (MS Thesis). 

Mary-Kathryn Harrod-Byrd (2021) Serial measurements of circulating glucose and luteinizing hormone concentrations in lactating dairy cattle (MS Thesis).

Constantino J. Preantral Follicle Numbers and Size in Heifers Carrying the Bovine High Fecundity Allele Trio. OSU Undergraduate Honors thesis.

Cooper L. Circulating AMH, antral follicle count and ovulation rate after unilateral ovariectomy in cattle: influence of the bovine fecundity allele Trio. OSU Undergraduate Honors thesis.

Cunningham, Devin (2021) Effects of an extruded flaxseed supplement on plasma haptoglobin, non-esterified fatty acids, beta-hydroxybutyrate, and complete blood count in transition dairy cows and heifers. (MS Thesis).

Gurung S (2021). Bovine synepitheliochorial placentation is a barrier to fetal microchimerism. (MS Thesis)

Michelle L. Kott (2021). Effects of mid-gestational L-citrulline supplementation to twin-bearing ewes on umbilical blood flow, placental development, and lamb production traits (MS Thesis). 

Maucieri AM, Townson DH (2020) Characterization and manipulation of O-GlcNAcylation in granulosa cells of bovine ovarian antral follicles. UVM MS Thesis

Mary Ali Oliver. The effect of endometrial cell conditioned media on in vitro cultured bovine embryo development. (MS Thesis; DJM MS student)

Schalich KM (2021). Analysis of aspects of the uterine environment and of early mammary secretions critical for embryonic, fetal, and neonatal development in cattle. (PhD Thesis)

Zackary K. Seekford (2020). Interleukin-6 Supplementation Improves Post-Transfer Embryonic and Early Fetal Development of In Vitro Produced Bovine Embryos (MS Thesis).

Planned Master’s Thesis: “Epidermal Growth Factor and Leukemia Inhibitory Factor Supplementation in Matrix-free, Three-Dimensional Bovine Follicle Culture.” Wilson Simmons, M.S. 09/2021. Major Professor C. Bishop. 

Sarah Singleton. Novel postpartum reproductive phenotypes in beef cattle. (Undergraduate Chancellor’s Honor’s Thesis; SEM undergraduate student)

Master’s Thesis: “Increasing vitamin D levels to improve fertilization rates in cattle.” Vanessa Peixoto de Souza, M.S., D.V.M. 06/14/2021. Major Professors C. Estill and C. Bishop.

Lydia K. Wooldridge (2020). Supplementing Bovine Embryo Culture Media to Improve the Production and Quality of In Vitro Produced Bovine Embryos (PhD Dissertation).

 Active collaboration within the group

OSU and WI: evaluated and currently working on projects to evaluate the effect of dose of GnRH at initiation of a 5-day synchronization protocol for FTET. 

NY and WI: working collaboratively on projects to determine physiological differences among cows of different genetic merit for fertility.

PA and WV: Samples shared for analysis of molecular regulators of luteal function.

 In addition to Hatch Multistate Funds, these studies were supported by:

 USDA NIFA/AFRI

 Oregon State University Animal and Rangeland Sciences Department Funds

 Oregon State University Agricultural Research Foundation

 Oregon Beef Council

 OARDC SEEDS Early career investigator – The Ohio State University

 CFAES Honors Will C. Hauk Endowment Grant – Undergraduate student - The Ohio State University

 National Institute of Environmental Health Science

 Iowa State University Nutritional Sciences Council Martin Fund

 National Pork Board

 Texas A&M University - Triads for Transformation

 American Simmental Association

 University of Tennessee AgResearch Instrumentation Grants program

 NIH-R21

 Binational Agriculture Research and Development (BARD)

 Office of Research and Economic Development, Univ Nebraska-Lincoln

Bill and Melinda Gates Foundation

NIH/NIGMS-sponsored Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training (T32)

08/05/2022

Crites, B.R., S.N. Carr, J.C. Matthews and P.J. Bridges. 2022. Form of dietary selenium affects mRNA encoding cholesterol biosynthesis and immune response elements in the early luteal phase bovine corpus luteum. Journal of Animal Science. In Press.

Crites, B.R., S.N. Carr, L.H. Anderson, J.C. Matthews and P.J. Bridges. 2022. Form of dietary selenium affects mRNA encoding interferon-stimulated and progesterone-induced genes in the bovine endometrium and conceptus length at maternal recognition of pregnancy. Journal of Animal Science. In Press.

Carr, S.N., B. Crites, J.L. Pate, C.H.K. Hughes, J.C. Matthews and P.J. Bridges. 2022. Form of supplemental selenium affects the expression of mRNA transcripts encoding selenoproteins, and proteins regulating cholesterol uptake, in the corpus luteum of grazing beef cows. Animals. 12:313.

 

Menichetti B.T., Garcia-Guerra A, Lakritz J., Weiss, W. P. Velez J. S., Bothe H., Merchan D., Schuenemann G. M. 2021. Effect of timing of prepartum vaccination relative to pen change with an acidogenic diet on lying time and metabolic profile in Holstein dairy cows. Journal of Dairy Science, 104 (10): 11059-11071.

 

Menichetti B.T., Garcia-Guerra A, Lakritz J., Weiss, W. P. Velez J. S., Bothe H., Merchan D., Schuenemann G. M. 2021. Effects of prepartum vaccination timing relative to pen change with an acidogenic diet on serum and colostrum immunoglobulins in Holstein dairy cows. Journal of Dairy Science, 104 (10): 11072-11081.

 

Duran B. J., F. L. V. Pinaffi, J. C. L. Motta, C. Hayden, A. E. Crist, C. Rykaczewski, S. Wellert, E. Rojas-Canadas, M. L. Mussard, A. García-Guerra. 2021. “Corpus luteum regression after induced pregnancy loss in cattle is preceded by a reduction in uterine artery vascular perfusion”. Abstract P136. Proceedings of the 54^th Annual Meeting of the Society for the Study of Reproduction 2021, December 13-18, St Louis, MO.

 

García-Guerra A., L. Cooper, B. W. Kirkpatrick, M. C. Wiltbank. 2021. “Circulating AMH, antral follicle count, and ovulation rate after unilateral ovariectomy in cattle: influence of the bovine fecundity allele Trio”. Abstract P150. Proceedings of the 54^th Annual Meeting of the Society for the Study of Reproduction 2021, December 13-18, St Louis, MO.

 

Crist A., J. C. L. Motta, C. Hayden, B. Duran, M. Mussard, A. Garcia-Guerra. 2021. “Ovarian dynamics and fertility in beef cows administered a 5-day or 6-day CO-Synch protocol for timed artificial insemination”. Journal of Animal Science, Volume 99, Issue Supplement 4, November 2021, Page XX.

 

Motta J. C. L., R. V. Sala, V. A. Absalón-Medina, V. C. Fricke, M. Dominguez, D. C. Pereira, C. Hayden, E. R. Canadas, B. J. Duran, J. F. Moreno, A. García-Guerra. 2021. “Influence of length of porcine follicle-stimulating hormone (p-FSH) treatment before ovum pickup on ovarian response and in vitro embryo production in Holstein heifers”. Reproduction, Fertility and Development, 2021, Vol. 33 No. 2, Page 170-171.

 

Canadas E. R., B. Duran, G. Machado, A. Nall, S. E. Battista, M. Mussard, P. S. Baruselli, A. García-Guerra. 2021. “Presynchronization and reutilization of progesterone devices during a 6-day CO-Synch protocol for fixed-time artificial insemination in beef heifers”. Reproduction, Fertility and Development, 2021, Vol. 33 No. 2, Page 165-166.

 

Brochado C., B. J. Duran, J. C. L. Motta, J. D. Kieffer, A. Pinczak, A. Menchaca, A. García-Guerra. 2021. “Simplification of the follicle-stimulating hormone protocol for superovulation of the first follicular wave in sheep”. Reproduction, Fertility and Development, 2021, Vol. 33 No. 2, Page 182.

 

Duran B. J., J. C. Lemos-Motta, E. Rojas-Canadas, C. Hayden, C. Rykaczewski, A. Nall, M. L. Mussard, A. García-Guerra. 2021. “Timing of luteolysis and conceptus expulsion after induced pregnancy loss at three different timepoints after maternal recognition of pregnancy in cattle”. Reproduction, Fertility and Development, 2021, Vol. 33 No. 2, Page 131.

 

Hayden C., R. V. Sala, D. C. Pereira, L. C. Carrenho-Sala, M. Fosado, D. Moreno, J. F. Moreno, A. García-Guerra. 2021. “Effect of follicle-stimulating hormone dose and circulating progesterone before ovum pickup and in vitro embryo production in pregnant Holstein heifers”. Reproduction, Fertility and Development, 2021, Vol. 33 No. 2, Page 143.

 

Goulet MR, Hutchings D, Donahue J, Elder D, Tsang PCW. 2022. Regulation of cellular communication network factor 1 by Ras homolog family member A in bovine steroidogenic luteal cells. J Anim Sci, in press

Hughes CHK, Rogus A, Inskeep EK, Pate JL. 2021. NR5A2 and potential regulatory miRNAs in the bovine CL during early pregnancy. Reproduction https://doi.org/10.1530/REP-20-0009

Carr SN, Crites BR, Pate JL, Hughes CHK, Matthews JC, Bridges PJ. 2022. Form of Supplemental Selenium Affects the Expression of mRNA Transcripts Encoding Selenoproteins, and Proteins Regulating Cholesterol Uptake, in the Corpus Luteum of Grazing Beef Cows. Animals2022,12,313. https:// doi.org/10.3390/ani12030313

Hughes CHK, Mezera M, Wiltbank M, Pate JL. 2022. Insights from two independent transcriptomic studies of the bovine corpus luteum of pregnancy. J Anim Sci. in press

Bishop C, Selvaraj V, Townson D, Pate J, Wiltbank M. 2022. History, insights and future perspectives on studies into luteal function in cattle. J Anim Sci in press

Oh, J., Harper, M. T., Melgar, A., Raisanen, S., Chen, X., Nedelkov, K., Fetter, M., Ott, T., Wall, E. H., & Hristov, A. N. (2021). Dietary supplementation with rumen-protected capsicum during the transition period improves the metabolic status of dairy cows. Journal of Dairy Science, 104(11), 12 pages. DOI: https://doi.org/10.3168/jds.2020-19892

Fetter, M. E., Cunningham, D. M., Gambonini, F., Raisanen, S. E., Ott, T. L., & Hristov, A. N. (2021). Short communication: Postpartum plasma amino acid concentration in primi- and multiparous Holstein cows. Animal Feed Science and Technology, 281, 8 pages. DOI: https://doi.org/10.1016/j.anifeedsci.2021.115101

Ott, TL. An interview with Dr. Fuller Warren Bazer. (2021). Biology of Reproduction 104(2), 248-251.

Jachter SL, Simmons WP, Estill C, Xu J, Bishop CV. Matrix-free three-dimensional culture of bovine secondary follicles to antral stage: Impact of media formulation and epidermal growth factor (EGF). Theriogenology. 2022 Mar 15;181:89-94. doi: 10.1016/j.theriogenology.2022.01.013. Epub 2022 Jan 12. PMID: 35066368; PMCID: PMC8871473.

de Souza V.P., Jensen J., Estill C., Bishop C. V. Increasing vitamin D levels to improve fertilization rates in cattle. Manuscript Accepted Journal of Animal Sciences, 05/5/2022. 

Bishop, C.V. Selvaraj, V. Townson, D.H., Pate, J.L., Wiltbank, M.C. History, Insights, and Future Perspectives on Studies into Luteal Function in Cattle. Manuscript Accepted Journal of Animal Sciences, 04/12/2022.

Ault-Seay T. B., R. R. Payton, S. E. Moorey, K. G. Pohler, F. N. Schrick, E. A. Shepherd, B. H. Voy, K. H. Lamour, D. J. Mathew, P. R. Myer and K. J. McLean. 2022. Bovine uterine endometrial response to lipopolysaccharide in the luteal and follicular phases between the contralateral and ipsilateral horns. Frontiers in Animal Science. In Review.

 

Ault-Seay T. B., K. J. Brandt, M. T. Henniger, R. R. Payton, D. J. Mathew, S. E. Moorey, F. N. Schrick, K. G. Pohler, T. P. L. Smith, J. D. Rhinehart, L. G. Schneider, K. J. McLean and P. R. Myer. 2022. Bacterial communities of the uterus and rumen during heifer development with protein supplementation. Frontiers in Animal Science. In Review.

 

Watson, E.M., K.A. Kurth, D.L. Metts, S.E. Moorey, B.F. Miller, and L.I. Muller. 2022. Evaluating the efficacy of large-scale, non-invasive fecal sampling for pregnancy detection in elk. Journal of Wildlife Diseases. In Review.

 

Walker B.N., J.L. Nix, C. Wilson, M.A. Marrella, S.L. Speckhart, L. Wooldridge, C. Yen, J.S. Bodmer, L.T. Kirkpatrick, S.E. Moorey, D.E. Gerrard, A. Ealy, and F.H. Biase. 2022. Tight gene co-expression between oocyte and surrounding cumulus is critical for oocyte developmental competence. Biology of Reproduction In Review.

 

Klabnik J., L.K. Christenson, S. Gunewardena, K.G. Pohler, L.A. Rispoli, R.R. Payton, S.E. Moorey, F.N. Schrick and J.L. Edwards. 2022. Heat-induced increases in body temperature in lactating dairy cows: impact on the cumulus and granulosa cell transcriptome of the periovulatory follicle. Journal of Animal Science. Accepted; In Press.

 

Liles, H.L., L.G. Schneider, K.G. Pohler, R.V. Oliveira Filho, F.N. Schrick, R.R. Payton, J.D. Rhinehart, K.W. Thompson, K. McLean, J.L. Edwards. 2022. Positive relationship of rectal temperature at fixed timed artificial insemination on pregnancy outcomes in beef cattle. Journal of Animal Science Accepted; In Press.

 

 

Moorey, S.E., E.A. Hessock, and J.L. Edwards. Pre-ovulatory follicle contributions to oocyte competence: 2022. Importance of the ever-evolving intrafollicular environment leading up to the LH surge. Journal of Animal Science. Accepted, In press.

 

Horn, E.J., C.C. Read, J.L. Edwards, F.N. Schrick, J.D. Rhinehart, R.R. Payton, S.R. Campagna, H.F. Castro, J.L. Klabnik, H.M. Clark, P.R. Myer, K.J. McLean, and S.E. Moorey. 2022. Pre-ovulatory follicular fluid and serum metabolome profiles in beef cows with thin, moderate, and obese body condition. Journal of Animal Science. Accepted; In Press.

 

Read, C.C., J.L. Edwards, F.N. Schrick, J.D. Rhinehart, R.R. Payton, S.R. Campagna, H.F. Castro, J.L. Klabnik, and S.E. Moorey. 2022. Pre-ovulatory serum estradiol concentration is positively associated with oocyte ATP and follicular fluid metabolite abundance in lactating beef cattle. Journal of Animal Science. Accepted, In Press.

 

Mathew D. J., K. D. Peterson, L. K. Senn, M. A. Oliver and A. D. Ealy. 2022. Review: Ruminant Conceptus-Maternal Interactions: Interferon Tau and Beyond. Journal of Animal Science. doi: 10.1093/jas/skac123. Accepted, In Press. Embargo until July, 2022.

 

Read, C.C., J.L. Edwards, F.N. Schrick, J.D. Rhinehart, R.R. Payton, S.R. Campagna, H.F. Castro, J.L. Klabnik, E.J. Horn, and S.E. Moorey. Correlation between pre-ovulatory follicle diameter and follicular fluid metabolome profiles in lactating beef cows. Metabolites. 2021. 11(9):623. doi: 10.3390/metabo11090623.

 

Read, C.C., S. Bhandari, and S.E. Moorey. 2021. Concurrent measurement of mitochondrial DNA copy number and ATP concentration in single bovine oocytes. Methods and Protocols. 4(4):88. doi: 10.3390/mps4040088.

 

Chaney H. L., L. F. Grose, J. M. LaBarbara, A. W. Sirk, A. M. Blancke, J. M. Sánchez, C. Passaro, P. Lonergan, and D. J. Mathew. 2021. Galectin-1 induces gene and protein expression related to maternal-conceptus immune tolerance in bovine endometrium. Biology of Reproduction. 106(3):487-502. doi: 10.1093/biolre/ioab215

Moorey, S.E., J.M. Monnig, M.F. Smith, M.S. Ortega, J.A. Green, K.G. Pohler, G.A. Bridges, S.K. Behura, T.W. Geary. Differential transcript profiles in cumulus-oocyte complexes originating from pre-ovulatory follicles of varied physiological maturity in beef cows. Genes. 2021. 12(6), 893. doi: 10.3390/genes12060893.

 

Bisinotto RS, Ribeiro ES, Greco LF, Taylor-Rodriguez D, Ealy AD, Ayres H, Lima FS, Martinez N, Thatcher WW, Santos JEP. Effects of progesterone concentrations and follicular wave during growth of the ovulatory follicle on conceptus and endometrial transcriptome in dairy cows. J Dairy Sci. 2022 105:S0022-0302(21)00928-0. doi: 10.3168/jds.2021-20193.

 

Byrd MKH, Arneson AG, Soffa DR, Stewart JW, Rhoads ML. Human continuous glucose monitors for measurement of glucose in dairy cows. J Dairy Sci Comm. 2022, 3(1): 78-83. https://doi.org/10.3168/jdsc.2021-0147.

 

Ealy AD, Speckhart SL, Wooldridge LK. Cytokines that serve as embryokines in cattle. Animals 2021, 11(8), 2313; https://doi.org/10.3390/ani11082313

 

Fontes PLP, Oosthuizen N, Ciriaco FM, Sanford CD, Canal LB, Cooke RF, Pohler KG, Henry DD, Mercadante VRG, Ealy AD, Johnson SE, DiLorenzo N, Lamb GC. Effects of nutrient restriction on the metabolic profile of Bos indicus-influenced and Bos taurus suckled beef cows. Animal. 2021 Mar;15(3):100166. doi: 10.1016/j.animal.2020.100166.

 

Kott ML, Pancini S, Speckhart SL, Kimble LN, White RR, Stewart JL, Johnson SE, Ealy AD. Effects of mid-gestational L-citrulline supplementation to twin-bearing ewes on umbilical blood flow, placental development and lamb production traits. Transl Anim Sci. 2021 Jun 9;5(3):txab102. doi: 10.1093/tas/txab102.

Owens CE, Huffard HG, Nin-Velez AI, Duncan J, Teets CL, Daniels KM, Ealy AD, James RE, Knowlton KF, Cockrum RR. Microbes of various maternal body systems are predictive of calf digestive bacterial ecology. Animals. 2021 Jul 26;11(8):2210. doi: 10.3390/ani11082210.

 

Seekford ZK, Wooldridge LK, Dias NW, Timlin CL, Sales AF, Speckhart SL, Pohler KG, Cockrum RR, Mercadante VGR, Ealy AD. Interleukin-6 supplementation improves post-transfer embryonic and fetal development of in vitro-produced bovine embryos. Theriogenology. 2021 Aug;170:15-22. doi: 10.1016/j.theriogenology.2021.04.004. Epub 2021 Apr 28.

 

Timlin CL, Lynn A, Wooldridge LK, Uh K, Ealy AD, White RR, Lee K, Mercadante VRG. Physical parameters of bovine activated oocytes and zygotes as predictors of development success. Zygote. 2021 Mar 19:1-7. doi: 10.1017/S0967199421000058.

 

Wooldridge LK, Ealy AD. Interleukin-6 promotes primitive endoderm development in bovine blastocysts. BMC Dev Biol. 2021 Jan 12;21(1):3. doi: 10.1186/s12861-020-00235-z.

 

Wooldridge LK, Ealy AD. Leukemia inhibitory factor stimulates primitive endoderm expansion in the bovine inner cell mass. Front Anim Sci 2021. 2:796489. doi: 10.3389/fanim.2021.796489

 

Przygrodzka E, Monaco CF, Plewes MR, Li G, Wood JR, Cupp AS, and Davis JS (2021) Protein kinase A and 5’ AMP-activated protein kinase signaling pathways exert opposite effects on induction of autophogy in luteal cells. Front Cell Dev Biol, 9:723563, PMID: 34820368 

 

McFee RM, Romereim SM, Snider AP, Summers AF, Pohlmeier WE, Kurz SG, Cushman RA, Davis JS, Wood JR, and Cupp AS (2021). A high-androgen microenvironment inhibits granulosa cell proliferation and alters cell identity. Mol Cell Endocrinol, 531:111288, PMID: 33905753 

 

Snider AP, Romereim SM, McFee R, Summers AF, Pohlmeier WE, Kurz SG, Davis JS, Wood JR, and Cupp AS (2021) Transcriptomic data of bovine ovarian granulosa cells of control and High A4 cows. Data in Brief, 37:107217, PMID: 34189206, PMCID: PMC8220326 

 

Nafziger S, Tenley S, Summers AF, Abedal-Majed MA, Hart M, Bergman J, Kurz SG, Davis JS, Wood JR, Cupp AS (2021). Attainment and maintenance of pubertal cyclicity may predict reproductive longevity in beef heifers. Biol Reprod 104:1360-1372, PMID 33709137 

Bidne KL, Rister AL, McCain AR, Hitt BD, Dodds ED, and Wood JR. (2021) Maternal obesity alters placental lysophosphatidylcholine, lipid storage, and the expression of genes associated with lipid metabolism. Biol Reprod 104: 197-210, PMID: 33048132, PMCID: PMC7946805 Editor’s choice, Cover Image

 

Rial C., Laplacette A.L., and Giordano J.O.* 2022. Effect of a targeted reproductive management program designed to prioritize insemination at detected estrus and optimize days to insemination on the reproductive performance of lactating dairy cows. J. Dairy Sci. (In Press)

 

Giordano J. O. *, E. M. Sitko, C. Rial, M. M. Perez and G. E. Granados. 2022. Use of multiple biological, management, and performance data for the design of targeted reproductive management strategies for dairy cows. J. Dairy Sci. 105:4669-4678. https://doi.org/10.3168/jds.2021-21476

 

Schilkowsky E. M., G. E. Granados, E M. Sitko, M. Masello, M. M. Perez, J. O. Giordano*. 2021. Evaluation and characterization of estrus alerts and behavioral parameters generated by an ear-attached accelerometer-based system for automated detection of estrus. J. Dairy Sci. 104:6222-6237. https://doi.org/10.3168/jds.2020-19667    

 

Abstracts for scientific conferences

 

Matthews J.C., Q. Li, K.C. Chen and P.J. Bridges. 2022. Sensitivity of pituitary and hepatic selenoprotein transcriptomes to consumption of ergot alkaloids in growing cattle. 12^th International Symposium on Selenium in Biology and Medicine.

Webb K., R.J. Trotta, P. Bridges and J.C. Matthews. July 2021. Ad libitum consumption of a 1:1 blend of inorganic:organic Se by steers grazing endopyte-infected tall fescue increases serum prolactin and alkaline phosphatase activity, but not average daily gain. ASAS-CSAS Annual Meetings & Trade Show, Louisville, KY.

 

Hutchings DW, Elder D, Tsang PCW.  2022. Does the phytoestrogen Daidzein stimulate angiogenic factors in bovine steroidogenic luteal cells? 56^th Annual Meeting of the Society for the Study of Reproduction, Spokane, Washington.

 

da Silva M, Oli N, Gambonini F, Pate J, Ott T. 2021. Changes in immune cell populations and phenotype in peripheral blood leukocytes of dairy cows and heifers during early pregnancy. Society for the Study of Reproduction. Annual Meeting, St Louis, MO, Dec 12-15^th

Hughes CHK, Pate JL. 2022. MicroRNA may regulate luteal cell susceptibility to cell death during acquisition of luteolytic capacity. Int Cong Anim Reprod. Bologna, IT

Peterson, K. D., M. A. Oliver, J. L. Edwards, R. R. Payton, T. M. Prado, L. G. Strickland and D. J. Mathew. 2022. Utilization of a conceptus-endometrial co-culture system to investigate endometrial gene expression and histotroph dependent on conceptus origin. 19th International Conference on Animal Reproduction (ICAR), Bologna, Italy.

 

Ault-Seay, T. B., K. J. Brandt, M. T. Henniger, D. J. Mathew, S. E. Moorey, F. N. Schrick, K. G. Pohler, J. D. Rhinehart, L. G. Schneider, K. J. McLean, P. R. Myer. 2021. Bacterial Communities in the Uterus and Rumen of Beef Heifers throughout Development with Protein Supplementation. American Society of Animal Science (ASAS) Southern Section. Fort Worth, TX, USA.

 

Payton, R.R., A.M. Saxton and J.L. Edwards. 2021. Differences in the responsiveness of maturing bovine oocytes to an acute heat stress depending on month of the year. 54^th Annual Meeting of the Society for the Study of Reproduction (SSR), St Louis, MO.

 

Read, C.C., J.L. Edwards, F.N. Schrick, J.D. Rhinehart, R.R. Payton, S.R. Campagna, H.F. Castro, J.L. Klabnik, and S.E. Moorey. Influence of pre-ovulatory follicle size on the follicular fluid metabolome in lactating beef cows. 54^th Annual Meeting of the Society for the Study of Reproduction (SSR), St Louis, MO.

Horn, E.J., C.C. Read, J.L. Edwards, F.N. Schrick, J.D. Rhinehart, R.R. Payton, S.R. Campagna, H.F. Castro, J.L. Klabnik, and S.E. Moorey. Pre-ovulatory follicular fluid and serum metabolome profiles in beef cows with thin, moderate, and obese body condition. 54^th Annual Meeting of the Society for the Study of Reproduction (SSR), St Louis, MO.

Hessock, E.A., M.F. Smith, T.W. Geary, K.G. Pohler, J.A. Green, S.K. Behura, A.K. Stokes, and S.E. Moorey. Transcriptome profiles of in vivo matured bovine cumulus-oocyte complexes reveal unique gene expression between the oocyte and cumulus cells. 54^th Annual Meeting of the Society for the Study of Reproduction (SSR), St Louis, MO.

Oliver, M.A., K.D. Peterson, S. Bhandari, R.R. Payton, L.G. Schneider, J.L. Edwards, and D.J. Mathew. The effect of endometrial cell conditioned media on in vitro cultured bovine embryo development. 54^th Annual Meeting of the Society for the Study of Reproduction (SSR), St Louis, MO.

Mathew, D.J., H.L. Chaney, L.F. Grose, G. Charpigny, S.K. Behura, I.M. Sheldon, J.G. Cronin, T.E. Spencer, and P. Lonergan. Effect of galectin-1 on bovine endometrial epithelial and fibroblast cell transcriptomes in 3D cell culture. 54^th Annual Meeting of the Society for the Study of Reproduction (SSR), St Louis, MO.

Peterson, K.D., M.A. Oliver, S. Bhandari, S.E. Moorey, and D.J. Mathew. 2021. The effect of small and large ovarian follicle fluid on oviduct cell gene expression in cattle. American Dairy Science Association 2021 Annual meeting. Virtual.

 

Oliver, M.A., K.D. Peterson, S. Bhandari and D.J. Mathew. Effect of progesterone on bovine endometrial cell expression of select transporters and growth factors. American Dairy Science Association 2021 Annual meeting. Virtual.

 

Arneson AG, Stewart JW, Harrod MK, Newberne HM, Burgess MK, Jordan JA, White RR, Ealy AD, El-Kadi SW, Rhoads RP, Rhoads ML. Impact of heat stress and glycemic state on plasma γ- aminobutyric acid (GABA) in lactating Holstein cows. 2021. J Dairy Sci. 104(suppl 1): 173.

 

Oliver MA, Speckhart SL, Ealy AD. Human recombinant interleukin-6 promotes inner cell mass development in bovine embryos. Society for the Study or Reproduction Annual Meeting, Spokane WA.

 

Speckhart SL, Farrell K, Wooldridge LK, Biase FH, Lee K, Ealy AD. Interleukin-6 signal transducer is involved in blastocyst development in cattle. 2022 Society for the Study or Reproduction Annual Meeting, Spokane WA.

 

Stewart JW, Newberne HM, Harrod MK, Arneson AG, Negron-Perez VM, White RR, El-Kadi SW, Ealy AD, Rhoads RP, Rhoads ML. Heat stress and glycemic state alter milk production and composition in Holstein dairy cows. 2021. J Dairy Sci. 104(suppl 1): 173.

 

Cunha TO, Statz LR, Domingues RR, Andrade JPN, Wiltbank MC, Martins JPN. Accessory corpus luteum induced by human chorionic gonadotropin on day 7 or days 7 and 13 of the estrous cycle affected follicular and luteal dynamics and luteolysis in lactating Holstein cows. J Dairy Sci 2022; 105:2631-2650.

Toledo MZ, Stangaferro ML, Gennari RS, Barletta RV, Perez MM, Wijma R, Sitko EM, Granados G, Masello M, Van Amburgh ME, Luchini D, Giordano JO, et al. Effects of feeding rumen-protected methionine pre- and postpartum in multiparous Holstein cows: Lactation performance and plasma amino acid concentrations. J Dairy Sci 2021; 104:7583-7603.

Stangaferro ML, Toledo MZ, Gennari RS, Perez MM, Gamarra CA, Sitko EM, Monteiro PLJ, Jr., Masello M, Prata AB, Granados GE, Van Amburgh ME, Luchini D, et al. Effects of feeding rumen-protected methionine pre- and postpartum on reproductive outcomes of multiparous Holstein cows. J Dairy Sci 2021; 104:11210-11225. **

Monteiro PLJ, Sartori R, Canavessi AMO, Melo LF, Motta JCL, Consentini CEC, Wiltbank MC. Accessory corpus luteum regression during pregnancy I: timing, physiology, and P4 profiles. Reproduction 2021; 162:473-482.

Monteiro PLJ, Gonzales B, Drum JN, Santos JEP, Wiltbank MC, Sartori R. Prevalence and risk factors related to anovular phenotypes in dairy cows. J Dairy Sci 2021; 104:2369-2383.

Monteiro PLJ, Gamarra CA, Genari RS, Prata AB, Barletta RV, Duran PG, Canavessi AMO, Sartori R, Wiltbank MC. Accessory corpus luteum regression during pregnancy II: reproductive outcomes. Reproduction 2021; 162:483-495.

Mezera MA, Li W, Wiltbank MC. Pregnancy-induced changes in the transcriptome of the bovine corpus luteum during and after embryonic interferon-tau secretiondagger. Biol Reprod 2021; 105:148-163.

Mezera MA, Li W, Liu L, Meidan R, Penagaricano F, Wiltbank MC. Effect of natural pre-luteolytic prostaglandin F2alpha pulses on the bovine luteal transcriptome during spontaneous luteal regressiondagger. Biol Reprod 2021; 105:1016-1029.

Cardoso Consentini CE, Wiltbank MC, Sartori R. Factors That Optimize Reproductive Efficiency in Dairy Herds with an Emphasis on Timed Artificial Insemination Programs. Animals (Basel) 2021; 11.

Alves R, Silva MA, Consentini CEC, LO ES, Folchini NP, Oliva AL, Prata AB, Goncalves JRS, Wiltbank MC, Sartori R. Hormonal combinations aiming to improve reproductive outcomes of Bos indicus cows submitted to estradiol/progesterone-based timed AI protocols. Theriogenology 2021; 169:89-99.

Mezera MA, Lauber MR, Beard AD, Cabrera EM, Wiltbank MC, Fricke PM. Effect of route of administration of dinoprost tromethamine on plasma profiles of 13,14-dihydro-15-keto-prostaglandin F2α and progesterone in lactating Holstein cows. JDS Communications 2021; 2:421-425.

Toledo MZ, Nienow C, Luchini D, Apelo SIA, Wiltbank MC. Quantification of bovine plasma amino acids via liquid chromatography-electrospray ionization-mass spectrometry: Comparison of underivatized and precolumn derivatized methods. JDS Communications 2021; 2:227-232.

Ermisch AF, Bidne KL, Bochantin KA, Wood JR (2021) Ovarian inflammation increases oocyte maternal mRNAs during maturation and alters expression of cumulus regulatory genes resulting in reduced developmental competence. 54^th Annual Meeting of the Society for the Study of Reproduction, St. Louis, MO, Oral presentation 

 

Bell B, Kurz SG, Abedal-Majed M, Springman S, Hart M, Snider AP, Wood JR, Davis JS, Cupp AS (2021) Anti-Mullerian Hormone and pro-inflammatory cytokines contribute to inflammation and follicle arrest while Vascular Endothelial Growth Factor A isoforms may rescue follicle progression in High A4 cow ovarian microenvironment. 54^th Annual Meeting of the Society for the Study of Reproduction, St. Louis, MO, Oral presentation 

 

Keane JA, Snider AP, Fudolig MA, Sutton CM, Bochantin KA, Bergman JW, Kurz SG, Hanford KJ, Wood JR, and Cupp AS (2021) Reductions in hematocrit and hemoglobin concentrations in non-cycling pubertal classification beef heifers may contribute to delayed pubertal attainment. 54^th Annual Meeting of the Society for the Study of Reproduction, St. Louis, MO, Poster.

 

Rial C., A. L. Laplacette, and J. O. Giordano*. 2021. Effect of first-service management programs including AI at detected estrus based on automated estrus alerts and estrus occurrence during the voluntary waiting period on reproductive outcomes of dairy cows. J. Dairy Sci. Vol. 104 (E-Suppl. 1).

 

Giordano, J.O*. 2021. Use of multiple biological, management, and performance data for the design of targeted reproductive management strategies for dairy cows. J. Dairy Sci. 104 (E-Suppl. 1).

 

Sitko, E. M., Pérez, M. M., Granados, G. E., Masello, M., J.O. Giordano*. 2021. Effect of reproductive programs that prioritized timed AI or AI at detected estrus on cash flow of primiparous dairy cows. J. Dairy Sci.; 104. (E-Suppl. 1).

 

Theses/Dissertations

 

Crites, Benjamin Ryne, "THE EFFECTS OF FORM OF SELENIUM ON THE BOVINE CORPUS LUTEUM, UTERINE ENDOMETRIUM, AND DEVELOPMENT OF THE CONCEPTUS" (2021)”. Theses and Dissertations--Animal and Food Sciences. 135. https://uknowledge.uky.edu/animalsci_etds/135 https://doi.org/10.13023/etd.2021.424

 

Helmers, AC. 2022. The role of microRNA, complement proteins and immune cells in bovine luteal function and rescue. PhD Dissertation. The Pennsylvania State University. (Pate)

Oli, N. 2022. Effects of the estrous cycle and early pregnancy on proportions and functions of peripheral immune cells in dairy cows and heifers. M.S. Thesis. The Pennsylvania State University. (Ott)

Master’s Thesis: “Increasing vitamin D levels to improve fertilization rates in cattle.” Vanessa Peixoto de Souza, M.S., D.V.M. 06/14/2021. Major Professors C. Estill and C. Bishop.

Casey Read. Effects of pre-ovulatory follicle physiological status on oocyte metabolic capacity. (PhD Dissertation, 2022; SEM PhD student).

Mary Ali Oliver. The effect of endometrial cell conditioned media on in vitro cultured bovine embryo development. (MS Thesis, 2021; DJM MS student)

Sarah Singleton. Novel postpartum reproductive phenotypes in beef cattle. (Undergraduate Chancellor’s Honor’s Thesis, 2021; SEM undergraduate student)

Alicia Arneson (2021). Evaluating the impact of heat stress and altered glycemic state on plasma gamma-aminobutyric acid (GABA) in lactating Holstein cows (MS thesis).

 

Mary-Kathryn Harrod-Byrd (2021). Serial measurements of circulating glucose and luteinizing hormone concentrations in lactating dairy cattle (MS Thesis).

 

Michelle L. Kott (2021). Effects of mid-gestational L-citrulline supplementation to twin-bearing ewes on umbilical blood flow, placental development, and lamb production traits (MS Thesis).

 

Dallas Soffa (2022). Effects of feed additives on uterine morphology and selected reproductive attributes (MS thesis).

 

Jacob Stewart (2021). Physiological consequences of exposure to heat stress and the mycotoxin zearalenone (MS thesis).