12/20/2012

Andrade, J. E., Twaddle, N.C., Helferich, W.G. and Doerge, D.R., (2010). Absolute Bioavailability of Isoflavones from Soy Protein Isolate-Containing Food in Female Balb/c Mice. J Agric Food Chem;58:4529-36.

Andrade, J.E., Ju, Y.H., Baker, C., Wei, X., Doerge, D.R. and W.G. Helferich, Long-term dietary exposure of genistein and soy protein isolate containing genistein affect the progression of human breast cancer (MCF-7) cells after genistein withdrawal in athymic mice. 2012. (Submitted).

Aronchik I, Chen T, Durkin KA, Horwitz MS, Preobrazhenskaya MN, Bjeldanes LF, Firestone GL. Target protein interactions of indole-3-carbinol and the highly potent derivative 1-Benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling. Mol Carcinog. 2011 Oct 19. doi: 10.1002/mc.20857.

Baldwin, T.T., Riley, R.T., Zitomer, N.C., Voss, K.A., Coulombe, R.A. Jr., Pestka, J.J., Williams, D.E. and Glenn, A.E. (2011) The Current State of Mycotoxin Biomarker Development in Humans and Animals and the Potential for Application to Plant Systems World Mycotoxin Forum J. 4:257-270.

Barnett BA and Weir TL (2012) Bacterial secretion. In: Secretions and Exudates in Biological Systems (eds. Baluska F, Vivanco JM). Springer, Berlin, Germany.

Beaver, L.M., Yu, T.-W., Sokolowski, E.I., Williams, D.E., Dashwood, R.H. and Ho, E. (2012). 3,3Diindolylmethane, but not Indole-3-Carbinol, Inhibits Histone Deacetylase Activity in Prostate Cancer Cells. Toxicol. Appl. Pharmcol. 263:345-351.

Benninghoff, A.D., Orner, G.A., Buchner, C., Hendricks, J.D., Duffy, A.M. and Williams, D.E. (2012) Promotion of Hepatocarcinogenesis by Perfluoroalkyl Acids in Rainbow Trout. Toxicol. Sci. 125:60-78.

Bondy, G.S., Mehta, R., Caldwell, D., Coady, L., Armstrong, C., Savard, M., Miller, J. D., Chomyshyn, E., Bronson, R., Zitomer, N.C., Riley, R.T. (2012) Effects of long term exposure to the mycotoxin fumonisin B1 in p53 heterozygous and p53 homozygous transgenic mice Food and Chemical Toxicology DOI 10.1016/j.fct.2012.07.024

Borresen EC, Henderson AJ, Kumar A, Weir TL, Ryan EP (2012) Fermented foods: Patented approaches and formulations for nutritional supplementation and health promotion. Recent Patents on Food, Nutrition & Agriculture. 4, in press.

Bulder, A. S., Arcella, D., Bolger, M., Carrington, C., Kpodo, K., Resnik, S., Riley, R.T., Wolterink, G., and Wu, F. (2012) Fumonisins (addendum), In: Safety evaluation of certain food additives and contaminants. Geneva, World Health Organization, WHO Food Additives Series, 65, 325-794.

Caiozzi G, Wong BS, Ricketts ML (2012) Dietary modification of metabolic pathways via nuclear hormone receptors. Cell Biochem Funct. 30(7):531-51. doi: 10.1002/cbf.2842. Epub 2012 Jul 2.

Callihan, P., Zitomer, N., Kennedy, P., Lynch, K.R., Riley, R.T. and Hooks, S.B. (2012) Distinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydro-sphingosine 1-phosphate in human neural progenitor cells. Neuropharmacology 62, 988-996.

Carey, S. A., Plopper, C. G., Hyde, D. M., Islam, Z., Pestka, J. J., and Harkema, J. R. (2012). Satratoxin-G from the black Mold Stachybotrys chartarum induces rhinitis and apoptosis of olfactory sensory neurons in the nasal airways of rhesus monkeys. Toxicol Pathol 40, 887-898.

Cho, Y., H. Kim, et al. (2011). "A chemoprotective fish oil- and pectin-containing diet temporally alters gene expression profiles in exfoliated rat colonocytes throughout oncogenesis." J Nutr 141(6): 1029-1035.

Cho, Y., N. D. Turner, et al. (2012). "A chemoprotective fish oil/pectin diet enhances apoptosis via Bcl-2 promoter methylation in rat azoxymethane-induced carcinomas." Experimental Biology & Medicine In press.

Cimafranca, M.A., Davila, J., Ekman, G.C., Andrews, R.N., Neese, S.L., Peretz, J., Woodling, K.A., Helferich, W.G., Sarkar, J., Flaws, J.A., Schantz, S.L., Doerge, D.R., and Cooke, P.S. (2010). Acute and chronic effects of oral genistein administration in neonatal mice. Biol Reprod. 2010 83(1):114-21.

Clarke, J.D., Hsu, A., Williams, D.E., Dashwood, R.H., Stevens, J.F., Thuillier, P, Shannon, J. and Ho, E. (2011) Metabolism and Tissue Distribution of Sulforaphane in Nrf2 Knockout and Wild-Type Mice. Pharmacol. Res. 28:3171-3179 NIHMSID #351443.

Crowell, S.R., Amin, S.G., Anderson, K.A., Krishnegowda, G., Sharma, A.K., Soelberg, J.J, Williams, D.E. and Corley, R.A. (2011). Preliminary Physiologically Based Pharmacokinetic Models for Benzo[a]Pyrene and Dibenzo[def,p]Chrysene in Rodents. Toxicol. Appl. Pharmacol. 257:365-376.

De Assis, S., Warri, A., Benitez, C., Helferich, W.G., and Hilakivi-Clarke, L.A., (2011). Protective effects of prepubertal genistein exposure on mammary tumorigenesis are dependent on BRCA1 expression. Cancer Prev Res. 4(9):1436-48.

de Roos B, Romagnolo DF. Proteomic approaches to predict bioavailability of fatty acids and their influence on cancer and chronic disease prevention. J Nutr. 2012 Jul;142(7):1370S-6S. Epub 2012 May 30. Review.

Du, M., Yang X., Hartman J.A., Cooke, P.S., Doerge D.R., Ju Y.H., Helferich, W.G. (2012). Low-dose dietary genistein negates the therapeutic effect of tamoxifen in athymic nude mice. Carcinogenesis. 33(4):895-901.

Feduccia AA, Wang Y, Simms JA, Yi HY, Li R, Bjeldanes L, Ye C, Bartlett SE. Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors. Pharmacol Biochem Behav. 2012:102(2):241-8.

Flannery, B. M., Clark, E. S., and Pestka, J. J. (2012). Anorexia induction by the trichothecene deoxynivalenol (vomitoxin) is mediated by the release of the gut satiety hormone peptide YY (PYY). Toxicol Sci.
Gelineau-van Waes, J., Rainey, M.A., Maddox, J. R., Voss, K. A., Sachs, A. J., Gardner, N. M., Wilberding, J. D. and Riley, R. T. (2012) Increased sphingoid base-1-phosphates and failure of neural tube closure after exposure to fumonisin or FTY720. Birth Defects Research Part A: Clinical and Molecular Teratology 2012 Sep 18. DOI: 10.1002/bdra.23074. [Epub ahead of print]

George, N. I., J. R. Lupton, et al. (2010). "Evaluation of fecal mRNA reproducibility via a marginal transformed mixture modeling approach." BMC Bioinformatics 11: 13.

He, K., Pan, X., Zhou, H. R., and Pestka, J. (2012a). Modulation of inflammatory gene expression by the ribotoxin deoxynivalenol involves coordinate regulation of the transcriptome and translatome. Toxicol Sci.

He, K., Zhou, H. R., and Pestka, J. J. (2012b). Mechanisms for ribotoxin-induced ribosomal RNA cleavage. Toxicol Appl Pharmacol. 265, 10-18

He, K., Zhou, H. R., and Pestka, J. J. (2012c). Targets and intracellular signaling mechanisms for deoxynivalenol-induced ribosomal RNA cleavage. Toxicol Sci 127, 382-390.

Hilakivi-Clarke, L. Andrade, J.E., and Helferich. W.G. (2010). Is Soy Consumption good or bad for the breast? J. Nutr. 140(12):2326S-34S.

Hintze, K.J., Benninghoff, A.D. and Ward, R.E. (2012) Formulation of the Total Western Diet (TWD) as a basal diet for rodent cancer studies. Journal of Agricultural and Food Chemistry 60 (27): 6736-6742.

Ho, E., Beaver, L.M., Williams, D.E. and Dashwood, R.H. (2011) Dietary factors and epigenetic regulation for prostate cancer. Adv. Nutr. 2:497-510.

Hsu, A., Bray, T.M., Helferich, W.G., Doerge, D.R., and Ho, E., (2010). Differential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cells. Exp. Biol. Med. 2010;235:90-7.

Hsu, A., Wong, C.P., Williams, D.E., Dashwood, R.H. and Ho, E. (2011). Promoter De-Methylation of Cyclin D2 by Sulforaphane in Prostate Cancer Cells. Clin. Epigenetics 3:3-

Jackson, L.S., Jablonski, J.J, Bullerman, L.B., Bianchini, A., Hanna, M.A., Voss, K.A., Hollub, A.D., Ryu D. (2011) Reduction of fumonisin B1 in corn grits by twin-screw extrusion. Journal of Food Science 76, T150-155.

Jeffery, J. L., N. D. Turner, et al. (2012). "Carotenoid bioaccessibility from nine raw carotenoid-storing fruits and vegetables using an in vitro model." J Sci Food Agric 92(13): 2603-2610.

Johnson TA, Sohn J, Inman WD, Estee SA, Loveridge ST, Vervoort HC, Tenney K, Liu J, Ang KK, Ratnam J, Bray WM, Gassner NC, Shen YY, Lokey RS, McKerrow JH, Boundy-Mills K, Nukanto A, Kanti A, Julistiono H, Kardono LB, Bjeldanes LF, Crews P. Natural product libraries to accelerate the high-throughput discovery of therapeutic leads. J Nat Prod. 2011;74(12):2545-55.
Johnson TA, Sohn J, Vaske YM, White KN, Cohen TL, Vervoort HC, Tenney K, Valeriote FA, Bjeldanes LF, Crews P. Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries. Bioorg Med Chem. 2012 Jul 15;20(14):4348-55.

Keller AC, Weir TL, Broeckling CD, Ryan EP (2012) Antibacterial activity and phytochemical profile of fermented Camellia sinensis (Fuzhuan tea). Food Research International. Under revision

Kim, J.E., Bunderson, B., Croasdell, A., and R.A. Coulombe, Jr. (2011) Functional Characterization of Alpha-class Glutathione S-transferases from the Turkey (Meleagris gallopavo) Toxicological Sciences doi: 10.1093/toxsci/kfr212

Kim, J.E., Bunderson, B., Croasdell, A., Reed, K.M, and R.A. Coulombe, Jr. (20XX) Alpha-class glutathione S-transferases in wild turkeys: Characterization and Role in Resistance to the Carcinogenic Mycotoxin AflatoxinB1. PLoS One (submitted for publication).

Kumar A, Henderson A, Forster GM, Chen MH, Goodyear AW, Bauer JE, Weir TL, Leach JE, Dow SW, Ryan EP (2012) Dietary Rice Bran Promotes Resistance to Salmonella Colonization and Mucosal Invasion in Mice. BMC Microbiology. 12, 71.

Kumar M, Roe K, Nerurkar PV, Namekar M, Orillo B, Verma S, Nerurkar VR. Impaired virus clearance, compromised immune response and increased mortality in type 2 diabetic mice infected with West Nile virus. PLoS One. 2012;7(8):e44682. doi: 10.1371/journal.pone.0044682. Epub 2012 Aug 31

Lemlioglu-Austin, D., N. D. Turner, et al. (2012). "Effects of sorghum [Sorghum bicolor (L.) Moench] crude extracts on starch digestibility, estimated glycemic index (EGI), and resistant starch (RS) contents of porridges." Molecules 17(9): 11124-11138.

Lemlioglu-Austin, D., N. D. Turner, et al. (2012.). "Effects of brans from specialty sorghum varieties on in vitro digestibility of soft and hard sorghum endosperm porridges." Cereal Chemistry 89: 190-197.

Leonardi, T., J. Vanamala, et al. (2010). "Apigenin and naringenin suppress colon carcinogenesis through the aberrant crypt stage in azoxymethane-treated rats." Exp Biol Med (Maywood) 235(6): 710-717.

McQuistan, T.J, Simonich, M.T., Pratt, M.M., Pereira, C.B, Hendricks, J.D., Dashwood, R.H., Williams, D.E. and Bailey, G.S. (2011) Cancer Chemoprevention by Dietary Chlorophylls: A 12,000-Animal Dose-Dose Matrix Biomarker and Tumor Study. Fd. Chem. Toxicol. Nov. 3 [Epub ahead of print].

Myung, K., Zitomer, N., Duvall, M., Glenn, A.H., Riley R.T. and Calvo A.M. (2012) The conserved global regulator VeA is necessary for maize seedling disease in Fusarium verticillioides Plant-Pathology 61, 152-160. 2012.

Neese, S.L., Bandara,S.B., Doerge, D.R., Helferich, W.G., Korol, D.L., Schantz, S.L. (2011). Effects of multiple daily genestein treatment on executive function in middle-aged rats. Neurotoxicology & Teratology. 34(1):187-95.
Neese, S.L., Wang, V.C., Doerge, D.R., Woodling, K.A., Andrade, J.E., Helferich, W.G., Korol, D.L., and Schantz, S.L., (2010). Impact of dietary genistein and aging on executive function in rats. Neurotoxicol Teratol. 32(2): p. 200-211.

Nerurkar PV, Nishioka A, Eck PO, Johns LM, Volper E, Nerurkar VR. Regulation of glucose metabolism via hepatic forkhead transcription factor 1 (FoxO1) by Morinda citrifolia (noni) in high-fat diet-induced obese mice. Br J Nutr. 2012 Jul;108(2):218-28.

Papoutsis AJ, Borg JL, Selmin OI, Romagnolo DF. BRCA-1 promoter hypermethylation and silencing induced by the aromatic hydrocarbon receptor-ligand TCDD are prevented by resveratrol in MCF-7 cells. J Nutr Biochem. 2012 Oct;23(10):1324-32. doi: 10.1016/j.jnutbio.2011.08.001. Epub 2011 Dec 23.

Parasramka, M., Ho, E., Williams, D.E. and Dashwood, R.H. (2011). MicroRNAs, Diet and Cancer Chemoprevention: New Mechanistic Insights on the Epigenetic Action of Phytochemicals. Molec. Carcinogenesis 51:213-230.

Parasramka, M.A., Dashwood, W.M., Wang, R., Abdelli, A., Bailey, G.S., Williams, D.E., Ho, E. and Dashwood, R.H. (2012) Let-7/c-Myc/Lin28 Axis in 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-Induced Rat Colon Tumors and the Influence of Dietary Spinach. Molec. Nutr. Fd. Res., in press.

Petrovi, D.; Sivapragasam, N.; Thavarajah, D.; Gelling, V.; Thavarajah, P. Resistant starch nanoparticles for potential colonic drug and nutrient delivery. Biomacromolecules (in preparation)

Petrovi, D.; Sivapragasam, N.; Thavarajah, D.; Gelling, V.; Thavarajah, P. (2013). Corn resistant starch nanoparticles as encapsulation material for micronutrient and pharmaceutical drug delivery. ACS National Meeting oral presentation (Abstract #12061); presenting author

Rajendran, P., Ho, E., Williams, D.E. and Dashwood, R.H. (2011) Dietary Phytochemicals, HDAC Inhibition and DNA Damage/Repair Defects in Cancer Cells. Clin. Epigenetics 3:4- NIHMS #346513.

Rajendran, P., Kidane, A.I., Yu, T.-W., Dashwood, W.-M., Löhr, C.V., Ho, E., Williams, D.E. and Dashwood, R.H. (201x) HDAC Turnover, CtIP Acetylation and Dysregulated DNA Damage in Colon Cancer Cells Treated With Sulforaphane and Related Dietary Isothiocyanates. Carcinogenesis, in press.

Rajendran, Praveen, DeLage, B., Dashwood, W.M., Yu, T.-W., Wuth, B., Williams, D.E., Ho, E. and Dashwood, R.D. (2011) Histone Deacetylase Turnover and Recovery in Sulforaphane-Treated Colon Cancer Cells: Competing Actions of 14-3-3 and Pin1 in HDAC3/SMRT Corepressor Complex Dissociation/Reassembly. Molec. Cancer 10:68 doi:10.1186/1476-4598-10-68.

Rawal, S., and R.A. Coulombe, Jr. (2011). Metabolism of Aflatoxin B1 in Turkey Liver Microsomes: The Relative Roles of Cytochromes P450 A15 and 3A37. Toxicology and Applied Pharmacology 254:349-354. doi:10.1016/j.taap.2011.05.010

Riley , R.T., Torres, O.,,Showker, J.L., Zitomer, N.C., Matute, J., Voss, K.A., Gelineau-van Waes, J., Maddox, J.R., Gregory, S.G., Ashley-Koch, A.E. (2012) The Kinetics of Urinary Fumonisin B1 Excretion in Humans Consuming Maize-Based Diets . Molecular Nutrition and Food Research 56, 1445-1455.

Riley, R.T., Voss, K.A., Coulombe, R.A. Jr., Pestka, J.J. and Williams, D.E. (2011) Developing Mechanism-Based and Exposure Biomarkers for Mycotoxins in Animals, in Determining Mycotoxins and Mycotoxigenic Fungi in Food and Feed, S. De Saeger (ed.), Ghent University, Woodhead Publishing Limited, Cambridge, U.K., Pp. 245-275.

Riley, R.T., Voss, K.A., Coulombe, R.A., Pestka, J.J. and D. E. Williams (2011). Developing mechanism-based and exposure biomarkers for mycotoxins in animals. In Determining Mycotoxins and Mycotoxigenic Fungi in Food and Feed (S. De Saeger, ed.) Woodhead Publishing LTD, Cambridge, UK. ISBN 978-1-84569-674-0

Riley, R.T., Voss, K.A., Showker, J.L., Torres, O., Matute, J., Maddox, J.R., Rainey, M.A., Gardner, N.M., Sachs, A., Gregory, S.G., Ashley-Koch, A.E., Krupp, D., and Gelineau-Van Waes, J. (2012) Development of Biomarkers to Assess Fumonisin Exposure and Birth Defects. In: World Nutrition Forum 2012, E.M. Binder, ed., pp 249-256, Anytime Publishing, Leicestershire, England.

Romagnolo DF, Dashwood R, Stover PJ, Waterland RA, Ziegler TR. Nutritional regulation of epigenetic changes. Adv Nutr. 2012 Sep 1;3(5):749-50. doi: 10.3945/an.112.002675.

Romagnolo DF, Davis CD, Milner JA. Phytoalexins in cancer prevention. Front Biosci. 2012 Jun 1;17:2035-58. Review.

Romagnolo DF, Milner JA. Opportunities and challenges for nutritional proteomics in cancer prevention. J Nutr. 2012 Jul;142(7):1360S-9S. Epub 2012 May 30. PubMed PMID: 22649262; PubMed Central PMCID: PMC3374671.

Romagnolo DF, Selmin OI. Flavonoids and cancer prevention: a review of the evidence. J Nutr Gerontol Geriatr. 2012;31(3):206-38. doi: 10.1080/21551197.2012.702534. PubMed PMID: 22888839.

Shorey, L., Castro, D.J., Baird, W., Siddens, B., Löhr, Matzke, M., Waters, K., Corley, R.A. and Williams, D.E. (2012) Transplacental Carcinogenesis with Dibenzo[d,e,f,p]chrysene (DBC): Timing of Maternal Exposures Determines Target Tissue Response in Offspring. Cancer Lett. 317:49-55.

Shorey, L.E., Hagman, A.M., Williams, D.E., Ho, E., Dashwood, R.H. and Benninghoff, A.D. (2012). 3,3-Diindolylmethane Induces G1 Arrest and Apoptosis in Human Acute T-Cell Lymphoblastic Leukemia Cells. PloS One 7:e34975.

Shorey, L.E., Williams, D.E., Ho, E., Dashwood, R.H. and Benninghoff, A.D. (2012) 3,3-Diindolylmethane induces G1 arrest and apoptosis in human acute T-cell lymphoblastic leukemia cells. PLoS ONE 7(4): e34975.

Siddens, L.K., Larkin, A., Krueger, S.K., Bradfield, C.A., Waters, K.M., Tilton, S.C., Pereira, C.B., Löhr, C.V., Arlt, V.M., Phillips, D.H., Williams, D.E. and Baird, W.M. (201x) PAHs as Skin Carcinogens: Comparison of Benzo[a]pyrene, Dibenzo[def,p]chrysene and Three Environmental Mixtures in the FVB/N Mouse. Toxicol. Appl. Pharmacol. 264:377-386.

Sivapragasam, N.; Petrovi, D.; Thavarajah, D.; Thavarajah, P. (2013). Carbohydrate based micro- and nano-materials for functional food and pharmaceutical application

Solhaug, A., Vines, L. L., Ivanova, L., Spilsberg, B., Holme, J. A., Pestka, J., Collins, A., and Eriksen, G. S. (2012). Mechanisms involved in alternariol-induced cell cycle arrest. Mutat Res. 738-739,1-11

Tang, L., Yang, X., Dobrucki, W.L., Chaudhury, I., Yin, Q., Yao, C., Lezmi, S., Lu, Y., Helferich, W.G., Fan, T.M., and Cheng. J. Aptamer-functionalized, ultra-small, monodisperse silica nanoconjugate for targeted dual-modal imaging of lymph nodes with metastatic tumors. 2012. Angewandte Chemie. In Press.

Turner, N. D. and J. R. Lupton (2011). "Dietary fiber." Adv Nutr 2(2): 151-152.

Turner, P. C., Flannery, B., Isitt, C., Ali, M., and Pestka, J. (2012). The role of biomarkers in evaluating human health concerns from fungal contaminants in food. Nutr Res Rev 25, 162-179.

Turner, R.T., Iwaniec, U.T., Olson, D.A., Branscum, A.J., Belosay, A., Wang, V.C., Neese, S.L., Andrade, J., Schantz, S.L., Doerge, D.R., Helferich, W.G. Physiologically Relevant Levels of Genistein Do Not Protect the Skeleton in Rat Models for Postmenopausal Bone Loss. 2012 (Submitted).

Voss, K.A., Riley, R.T., Jackson, L.S., Jablonski, J.E., Bianchini, A., Bullerman, L.B., Hanna, M.A., Ryu, D. (2011) Extrusion cooking with glucose supplementation of fumonisin contaminated corn grits protected against nephrotoxicity and disrupted sphingolipid metabolism in rats. Molecular Nutrition and Food Research 55, S312-S320.

Watterson, T.L., Hamilton, B., Martin, R., and R.A. Coulombe, Jr. (2012) Urban Particulate Matter Activates Akt in Human Lung Cells. Archives of Toxicology 86:121-135 DOI: 10.1007/s00204-011-0739-5.

Watterson, T.L., Hamilton, B., Martin, R., and R.A. Coulombe, Jr. (2011) Urban Particulate Matter Activates Akt in Human Lung Cells. Archives of Toxicology DOI: 10.1007/s00204-011-0739-5

Weir TL, Hu Y, Ryan EP, Lin W, Murray P, Fu D, Snook R, Xiao W. (2012) Medicinal teas: a review to summarize health benefits and highlight fermented tea. Herbalgram. 94: 45-49.

WHO (2011) World Health Organization. Evaluation of Certain Food Additives and Contaminants. Seventy-fourth Report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical report Series, no. 966, pp 136. (R.T. Riley Member of the Secretariat issuing the report)

Williams, D.E. (2011) The Rainbow Trout Liver Cancer Model: Response to Environmental Chemicals and Studies on Promotion and Chemoprevention. Comp. Biochem. Physiol. Part C 155:121-127.
Wu, W., Bates, M., Bursian, S. J., Link, J. E., Flannery, B. M., Sugita-Konishi, Y., Wantanabe, M., Zhang, H., and Pestka, J. J. (2012a). Comparison of emetic potencies of the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon x and nivalenol. Toxicol Sci.

Wu, W., Flannery, B. M., Sugita-Konishi, Y., Watanabe, M., Zhang, H., and Pestka, J. J. (2012b). Comparison of murine anorectic responses to the 8-ketotrichothecenes 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, fusarenon X and nivalenol. Food Chem Toxicol 50, 2056-2061.

Xing, H., Tang, L., Yang, X., Hwang, K., Wang, W., Yin, Q., Wong, N.Y., Dobrucki, L.W., Yasui, N., Katzenellenbogen, J.A., Helferich, W. Cheng, J., Lu, Y. Selective Delivery of an Anti-cancer Drug to Breast Cancers in Vitro and in Vivo with Nucleolin-Aptamer-Functionalized Liposomes. 2012 (Submitted).

Xu X, Hu Y, Xiao W, Huang J, He X, Wu J, Ryan EP, Weir TL (2012) Effects of fermented Camilla sinensis, Fuzhuan tea, on egg cholesterol and production performance in laying hens. J. Int. Food and Agric. Res. 1:6-10.

Yang, X., Belosay A., Hartman, J.A., Song H., Doerge D.R. and Helferich W.G., Estradiol increases ER± negative breast cancer metastasis in an experimental model. 2012. Clinical & Experimental Metastasis. In Press.

08/02/2016

Publications:

Kim, J.E., Bunderson, B., Croasdell, A., Reed, K.M, and R.A. Coulombe, Jr. (2013) Alpha-class glutathione S-transferases in Wild Turkeys: Characterization and Role in Resistance to the Carcinogenic Mycotoxin Aflatoxin B1. PLOS One 8(4): e60662. doi:10.1371/journal.pone.0060662

Bunderson, B., Kim, J.E., Croasdell, A., Mendoza, K, Reed, K.M, and R.A. Coulombe, Jr. (2013) Heterologous Expression and Functional Characterization of Avian Mu-Class Glutathione S-Transferases. Comp. Biochem. Physiol. C – Toxicol Pharmacol. 158: 109-116. DOI: 10.1016/j.cbpc.2013.05.007.

Wu, Y., McEwen, G.D., Tang, M., Yu, T., Dimmick, Zhou, A., Gilbertson, T.A., Coulombe, Jr., R.A., and J.R. Stevens. (2013) Sensing Biophysical Alterations of Human Lung Cells (A549) in the Context of Toxicity Effects of Diesel Exhaust Particles. Cell Biochem Biophys May 28 (epub ahead of print) DOI: 10.1007/s12013-013-9618-4

Watterson, T.L., Hamilton, B., Martin, R., and R.A. Coulombe, Jr. (2012) Urban Particulate Matter Activates Akt in Human Lung Cells. Archives of Toxicology 86:121-135 DOI: 10.1007/s00204-011-0739-5

Benninghoff, A.D.* and Williams, D.E. (2013) The role of estrogen receptor beta (ERβ) in transplacental cancer prevention by indole-3-carbinol.  Cancer Prevention Research 6(4): 339-348.

Chen CH, Ravishankar S, Marchello J, Friedman M. 2013. Antimicrobial activity of plant compounds against Salmonella Typhimurium DT104 in ground pork and the influence of heat and storage on the antimicrobial activity. J Food Prot 76(7):1264-9.

Choi S-H, Ahn J-B, Kim H-J, Im N-K, Kozukue N, Levin CE, Friedman M. 2012. Changes in free amino acid, protein and flavonoid content in jujube (Ziziphus jujube) fruit during eight stages of growth and antioxidative and cancer cell inhibitory effects by extracts. J Agric Food Chem 60(41):10245-55.

Choi SP, Kim SP, Nam SH, Friedman M. 2013. Antitumor effects of dietary black and brown rice brans in tumor-bearing mice: Relationship to composition. Mol Nutr Food Res 57(3):390-400.

Du W-X, Avena-Bustillos RJ, Woods RD, Breksa A, McHugh TH, Friedman M, Levin CE, Mandrell R. 2012. Sensory evaluation of baked chicken wrapped with antimicrobial apple and tomato edible films formulated with cinnamaldehyde and carvacrol. J Agric Food Chem 60(32):7799-804.

Friedman M. 2013. Review of the anticarcinogenic, cardioprotective, and other health benefits of tomato compounds lycopene, a-tomatine, and tomatidine in pure form and in fresh and processed tomatoes. J Agric Food Chem. 2013, Online; DOI.org/10.1021/jf402654e

Friedman M, Henika PR, Levin CE. 2013. Bactericidal activities of health-promoting, food-derived powders against the foodborne pathogens Escherichia coli, Listeria monocytogenes, Salmonella enterica, and Staphylococcus aureus. J Food Sci 78(2):M270-M5.

Friedman M, Rasooly R. 2013. Review of the inhibition of biological activities of food-related selected toxins by natural compounds. Toxins 5(4):743-75.

Juneja VK, Altuntas EG, Ayhan K, Hwang C-A, Sheen S, Friedman M. 2013. Predictive model for the reduction of heat resistance of Listeria monocytogenes in ground beef by the combined effect of sodium chloride and apple polyphenols. Int J Food Microbiol 164(1):54-9.

Juneja VK, Gonzales-Barron U, Butler F, Yadav AS, Friedman M. 2013. Predictive thermal inactivation model for the combined effect of temperature, cinnamaldehyde and carvacrol on starvation-stressed multiple Salmonella serotypes in ground chicken. Int J Food Microbiol 165(2):184-99.

Kim SP, Nam SH, Friedman M. 2013. Hericium Erinaceus (Lion's Mane) mushroom extracts inhibit metastasis of cancer cells to the lung in CT-26 colon cancer-transplanted mice. J Agric Food Chem 61(20):4898-904.

Moore-Neibel K, Gerber C, Patel J, Friedman M, Jaroni D, Ravishankar S. 2013. Antimicrobial activity of oregano oil against antibiotic-resistant Salmonella enterica on organic leafy greens at varying exposure times and storage temperatures. Food Microbiol 34(1):123-9.

Rasooly R, Hernlem B, Friedman M. 2013. Low levels of aflatoxin B1, ricin, and milk enhance recombinant protein production in mammalian cells. PLoS ONE 8(8):article no. e71682; doi:10.1371/journal.pone.0071682.

Rasooly R, Hernlem B, He X, Friedman M. 2013. Non-linear relationships between aflatoxin B1 levels and the biological response of monkey kidney Vero cells. Toxins 5(8):1447-61.

Rounds L, Havens CM, Feinstein Y, Friedman M, Ravishankar S. 2013. Concentration-dependent inhibition of Escherichia coli O157:H7 and heterocyclic amines in heated ground beef patties by apple and olive extracts, onion powder and clove bud oil. Meat Sci 94(4):461-7.

Todd J, Friedman M, Patel J, Jaroni D, Ravishankar S. 2013. The antimicrobial effects of cinnamon leaf oil against multi-drug resistant Salmonella Newport on organic leafy greens. Int J Food Microbiol 166(1):193-9.

Rajamoorthi A, Shrivastava S, Steele R, Nerurkar P, Gonzalez JG, Crawford S, Varvares M and Ray RB. Bitter Melon Reduces Head and Neck Squamous Cell Carcinoma Growth by Targeting c-Met Signaling. PLoS One. 2013 Oct 17;8(10):e78006. doi: 10.1371/journal.pone.0078006.

Rensvold JW, Ong SE, Jeevananthan A, Carr SA, Mootha VK and Pagliarini DJ, Complementary RNA and Protein Profiling Identifies Iron as a Key Regulator of Mitochondrial Biogenesis. Cell Reports, 2013, 3(1): 237-245.

Caiozzi G, Wong BS, Ricketts ML. Dietary modification of metabolic pathways via nuclear hormone receptors.Cell Biochem Funct. (2012) 30(7):531-51. doi: 10.1002/cbf.284

Bondy, G.S., Mehta, R., Caldwell, D., Coady, L., Armstrong, C., Savard, M., Miller, J. D., Chomyshyn, E., Bronson, R., Zitomer, N.C., Riley, R.T. (2012) Effects of long term exposure to the mycotoxin fumonisin B₁ in p53 heterozygous and p53 homozygous transgenic mice. Food and Chemical Toxicology. 50 (10), 3604-3613. (reported last year but without volume and pages)

Gelineau-van Waes, J., Rainey, M.A., Maddox, J. R., Voss, K. A., Sachs, A. J., Gardner, N. M., Wilberding, J. D. and Riley, R. T. (2012) Increased sphingoid base-1-phosphates and failure of neural tube closure after exposure tofumonisin or FTY720. Birth Defects Research Part A: Clinical and Molecular Teratology 94(10), 790-803. (reported last year but without volume and pages)

Pitt, J.I., Wild, C.P., Gelderblom, W.C.A., Miller, J.D., Riley, R.T., Wu, F. and Baan, R.A. (Eds). (2012).  Management Of Mycotoxins In Foods And Feeds For Improving Public Health.  165 pp., International Agency for Research on Cancer Scientific Publication No 158, Lyon, France.

Van der Westhuizen, L., Shephard, G. S., Gelderblom, W. C. A., Torres, and Riley, R.T. (2013) Fumonisin biomarkers in maize eaters and implications for human disease. World Mycotoxin Journal 6(3):223-232.

Voss, K.A., Riley, R.T., Moore, N.D., Burns, T.D. (2013) Alkaline cooking (Nixtamalization) reduced the in vivo toxicity of fumonisin-contaminated corn in a rat feeding bioassay. Food Additives and Contaminants. 30, 1415-1421.

Cho, Y., N.D. Turner, L.A. Davidson, R.S. Chapkin, R.J. Carroll, and J.R. Lupton.  2012.  A chemoprotective fish oil/pectin diet enhances apoptosis via Bcl-2 promoter methylation in rat azoxymethane-induced carcinomas.  Experimental Biology & Medicine 237:1387-1393.

Turner, N.D., L.E. Ritchie, R.S. Bresalier, and R.S. Chapkin.  The microbiome and colorectal neoplasia – environmental modifiers of dysbiosis.  Current Gastroenterology Reports 15(9):346.

Weir TL*, Manter DK, Sheflin AM, Barnett BA, Heuberger AH, Ryan EP (2013) Stool microbiome and metabolome differences between colorectal cancer patients and healthy adults. PLoS One. PLoS One 8(8): e70803. doi:10.1371/journal.pone.0070803

Keller AC, Weir TL*, Broeckling CD, Ryan EP (2013) Antibacterial activity and phytochemical profile of fermented Camellia sinensis (Fuzhuan tea). Food Research International. dx.doi.org/10.1016/j.foodres/2013.04.023

Borresen EC, Henderson AJ, Kumar A, Weir TL, Ryan EP (2012) Fermented foods: Patented approaches and formulations for nutritional supplementation and health promotion. Recent Patents on Food, Nutrition & Agriculture. 4,134-140.

Xu X, Hu Y, Xiao W, Huang J, He X, Wu J,  Ryan EP, Weir TL* (2012) Effects of fermented Camilla sinensis, Fuzhuan tea, on egg cholesterol and production performance in laying hens. J. Int. Food and Agric. Res. 1:6-10.

Parasramka, M.A., Dashwood, W.M., Wang, R., Saeed, H.H., Williams, D.E., Ho, E. and Dashwood, R.H. (2012) A Role for Low-Abundance miRNAs in Colon Cancer: the miR-206/Krüppel-Like Factor 4 (KLF4) Axis.  Clin. Epigenetics. 4:16 DOI: 10.1186/1868-7083-4-16.

Siddens, L.K., Larkin, A., Krueger, S.K., Bradfield, C.A., Waters, K.M., Tilton, S.C., Pereira, C.B., Löhr, C.V., Arlt, V.M., Phillips, D.H., Williams, D.E. and Baird, W.M. (2012) PAHs as Skin Carcinogens: Comparison of Benzo[a]pyrene, Dibenzo[def,p]chrysene and Three Environmental Mixtures in the FVB/N Mouse.  Toxicol. Appl. Pharmacol. 264:377-386. NIHMS 407423

*Benninghoff, A.D. and Williams, D.E. (2013) The Role of Estrogen Receptor Beta in Transplacental Cancer Prevention by Indole-3-Carbinol.  Cancer Prev. Res. 6:339-348.

Larkin, A., Siddens, L.K., Krueger, S.K., Tilton, S.C., Waters, K.M., Williams, D.E. and Baird, W.M. (2013) Application of a Fuzzy Neural Network Model in Predicting Polycyclic Aromatic Hydrocarbon-Mediated Perturbations of the CYP1B1 Transcriptional Regulatory Network in Mouse Skin.  Toxicol. Appl. Pharmacol. 267:192-199. NIHMS 441901

Shorey, L.E., Madeen, E.P., Atwell, L.L., Ho, E., Löhr, C.V., Pereira, C.B., Dashwood, R.H. and Williams, D.E. (2013) Differential Modulation of Dibenzo[def,p]chrysene Transplacental Carcinogenesis: Maternal Diets Rich in Indole-3-Carbinol Versus Sulforaphane. Toxicol. Appl. Pharmacol. 270:60-69.

Watson, G., Beaver, L., Williams, D., Dashwood, R. and Ho, E. (2013) Phytochemicals from Cruciferous Vegetables, Epigenetics, and Prostate Cancer Prevention. Am. Assoc. Pharmaceut. Sci., DOI: 10:10.1208/s12248-013-9504-4.

Kaur, P., Shorey, L., Ho, E., Dashwood, R.H. and Williams, D.E. (2013). The Epigenome as a Potential Mediator of Cancer Prevention and Disease Prevention in Prenatal Development.   Nutr. Rev. 71:441-457.

Crowell, S.R., Sharma, A.K., Amin, S., Soelberg, J.J., Sadler, N.C., Wright, A.T., Baird, W.M., Williams, D.E. and Corley, R.A. (2013) Impact of Pregnancy on the Pharmacokinetics of Dibenzo[def,p]chrysene in Mice. Toxicol. Sci. 135:48-62.

Liang, J.F., Q. Yang, M. J. Zhu, Y. Jin, M. Du. (2013). AMP-activated protein kinase (AMPK) α2 subunit mediates glycolysis in postmortem skeletal muscle. Meat Science, 95: 536-541

Hu, J., B. Wang, X. Fang, W.J. Means, R.J. McCormick, M. Gomelsky, and M. J. Zhu. (2013). c-di-GMP signaling regulates E. coli O157:H7 adhesion to colonic epithelium. Veterinary Microbiology, 164: 344-351

Yan, X.,Y. Huang, J. X. Zhao, C. J. Rogers, M. J. Zhu, S. P. Ford, P. W. Nathanielsz, and M. Du. (2013). Maternal obesity down-regulates microRNA let-7g expression, a possible mechanism for enhanced adipogenesis during ovine fetal skeletal muscle development. International Journal of Obesity, 37: 568-575

Harries, S.M., W.F. Yue, S.A. Olsen, J. Hu, W.J. Means, R.J. McCormick, M. Du, and M. J. Zhu. (2012). Salt at concentrations relevant to meat processing enhances Shiga toxin 2 production in Escherichia coli O157:H7. International Journal of Food Microbiology, 159:186-192

Wang, H., J. Zhao, N. Hu, J. Ren, M. Du, and M. J. Zhu. (2012). Side-stream smoking reduces inflammation and increases expression of tight junction proteins in the intestine. World Journal of Gastroenterology, 18: 2180-2187

Wang, H., J. Zhao, Y. Huang, X. Yan, A.M. Meyer, M. Du, K. Vonnahme, L.

Reynolds, J. Caton and M. J. Zhu. (2012). Effects of maternal plane of nutrition and increased dietary selenium in first parity ewe on inflammatory response in the ovine neonatal gut. Journal of Animal Science, 90: 325-333.

Yue, W.F., M. Du, and M. J. Zhu. (2012). High temperature in combination with UV irradiation enhances horizontal transfer of stx2 gene from E. coli O157:H7 to non- pathogenic E. coli. PLoS One, 7: e31308 (1-7)

Huang, Y., A. K. Das, Q. Y. Yang, M. J. Zhu, and M. Du. (2012). Zfp423 promotes adipogenic differentiation of bovine stromal vascular cells. PLoS One, 7: e47496.

Das, A. K., Q. Y. Yang, X. Fu, J. F. Liang, M. S. Duarte, M. J. Zhu, G. D. Trobridge, and M. Du. (2012). AMP-activated protein kinase stimulates myostatin expression in C2C12 cells. Biochemical and Biophysical Research Communications, 427:36-40.

Yan, X., M. J. Zhu, M. V. Dodson, and M. Du. (2012). Developmental programming of fetal skeletal muscle and adipose tissue development. Journal of Genomics, 1,29-38.

Huang, Y., J. X. Zhao, X. Yan, M. J. Zhu, N. M. Long, R. J. McCormick, S. P. Ford, P. W. Nathannielsz, and M. Du. (2012). Maternal obesity enhances collagen accumulation and cross-linking in skeletal muscle of ovine offspring. PLoS One. 7: e31691(1-8).

12/29/2014

Benninghoff, A.D. and Williams, D.E. (2013) The role of estrogen receptor beta (ER?) in transplacental cancer prevention by indole-3?carbinol. Cancer Prevention Research 6(4): 339?348.

Polejaeva, I., Broek, D., Walker, S., Zhou, W., Walton, M., Benninghoff, A.D., Faber, D. (2013) Longitudinal study of reproductive performance of female cattle produced by somatic cell nuclear transfer. PLoS ONE 8(12): e84283.

Hintze, K.J, Cox, J.E., Rompato, G., Benninghoff, A.D., Ward, R.E., Broadbent, J., and Lefevre, M. (2014) Broad scope method for creating humanized animal models for animal health and disease research through antibiotic treatment and human fecal transfer. Gut Microbes 5(2): 1-9.

Tang X, Kuhlenschmidt TB, Li Q, Ali S, Lezmi S, Chen H, Pires-Alves M, Laegreid WW, Saif TA, Kuhlenschmidt MS. (2014) A mechanically-induced colon cancer cell population shows increased metastatic potential. Mol Cancer. 13(1):131.

Monson, M. S., Settlage, R.E., McMahon, K.W., Mendoza, K.M., Rawal, S., El Nezami, H., Coulombe, R.A., and K.M. Reed. (2014) Response of the Hepatic Transcriptome to Aflatoxin B1 in Domestic Turkey. PLOS One 9(6): doi: 10.1371/journal.pone.0100930.

Rawal, S., Bauer, M. M., Mendoza, K.M., El?Nezami, H., Hall, J.O., Kim, J?E., Stevens, J.R., Reed, K.M., and R.A. Coulombe (2014). Aflatoxicosis Chemoprevention by Probiotic Lactobacillus and its Impact on BG Genes of the Major Histocompatibility Complex. Research in Veterinary Science. pii: S0034?5288(14)00170?2. doi: 10.1016/j.rvsc.2014.06.008.

Kim, J.E., Bunderson, B., Croasdell, A., Reed, K.M, and R.A. Coulombe, Jr. (2013) Alpha?class glutathione S? transferases in Wild Turkeys: Characterization and Role in Resistance to the Carcinogenic Mycotoxin Aflatoxin B1. PLOS One 8(4): e60662. doi:10.1371/journal.pone.0060662

Bunderson, B., Kim, J.E., Croasdell, A., Mendoza, K, Reed, K.M, and R.A. Coulombe, Jr. (2013) Heterologous Expression and Functional Characterization of Avian Mu?Class Glutathione S?Transferases. Comp. Biochem. Physiol. C – Toxicol Pharmacol. 158: 109?116. DOI: 10.1016/j.cbpc.2013.05.007.

Wu, Y., McEwen, G.D., Tang, M., Yu, T., Dimmick, Zhou, A., Gilbertson, T.A., Coulombe, Jr., R.A., and J.R. Stevens. (2013) Sensing Biophysical Alterations of Human Lung Cells (A549) in the Context of Toxicity Effects of Diesel Exhaust Particles. Cell Biochem Biophys 67(3):1147?56. doi: 10.1007/s12013?013?9618?4.

Anwar-Mohamed, A., Elshenawy, O.H., Soshilov, A.A., Denison, M.S., Le, X.C., Klotz, L.-O., El-Kadi, A.O.S. (2013) Methylated pentavalent arsenic metabolites are bifunctional inducers as they induce cytochrome P4501A1 (CYP1A1) and NAD(P)H:quinone oxidoreducatase (NQO1) through AhR and Nrf2 dependent mechanisms, Free Radical Biol. Med. 67C, 171-187. PMID: 24161444

Magiatis, P., Pappas, P., Gaitanis, G., Mexia, N., Melliou, E., Galanou, M., Vlachos, C., Stathopoulou, K., Skaltsounis, A.L., Marselos, M., Velegraki, A., Denison, M.S. and Bassukas, I.D. (2013) Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) receptor detected in diseased human skin, J. Invest. Dermatol. 133, 2023-2030. PMC3714356

DeGroot, D.E., Hayashi, A. and Denison, M.S. (2014) Lack of ligand-selective binding of the aryl hydrocarbon receptor to putative DNA binding sites regulating expression of Bax and Paraoxonase 1 genes, Arch. Biochem. Biophys. 541, 13-20. PMC3875388

Addeck, A., Croes, K., Van Langenhove, K., Denison, M.S., Elhamalawy, A., Elskens, M. and Baeyens, W. (2014) Time-integrated monitoring of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) in urban and industrial wastewaters using a ceramic toximeter and the CALUX bioassay, Chemosphere 94, 27-35. PMID: 24075528

Addeck, A., Croes, K., Van Langenhove, K., Denison, M.S., Afify, A.S., Gao, Y., Elskens, M. and Baeyens, W. (2014) Time-integrated monitoring of dioxin-like polychlorinated biphenyls (dl-PCBs) in aquatic environments using the ceramic toximeter and the CALUX bioassay. Talanta 120, 413-418. PMID: 24468390

Vogel, C.F.A., Khan, E.M., Chang, W.L.W., Wu, D., Haarmann-Stemmann, T., Hoffmann, A. and Denison, M.S. (2014) Cross-talk between aryl hydrocarbon receptor and the inflammatory response: a Role for NF-?B, J. Biol. Chem. 289, 1866-1875. PMC3894361

Soshilov, A.A. and Denison, M.S. (2013) Ligand promiscuity of aryl hydrocarbon receptor agonists and antagonists revealed by site directed mutagenesis, Molec. Cell. Biol. 34, 1707-1719. PMC3993610

Bessede, A., Gargaro, M., Pallotta, M.T., Matino, D., Servillo, G., Brunacci, C., Bicciato, S., Mazza, E.M.C., Macchiarulo, A., Vacca, C., Iannitti, R., Tissi, L., Volpi, C., Belladonna, M.L., Orabona, C., Bianchi, R., Lanz, T., Platten, M., Della Fazia, M.A., Piobbico, D., Zelante, T., Funakoshi, H., Nakamura, T., Gilot, D., Denison, M.S., Guillemin, G.J., DuHadaway, J.D., Prendergast, G.C., Metz, R., Geffard, M., Boon, L., Pirro, M., Iorio, A., Veyret, A., Romani, Grohmann, U., Fallarino, F. and Puccetti, P. (2014) Aryl hydrocarbon receptor control of a disease tolerance defense pathway, Nature 511, 184-190. PMC4098076

Ghorbanzadeh, M., van Ede, K.I., Larsson, M.N., van Duursen, M.B.M., Poellinger, L., Lucke, S., Machala, M., Pencikova, K., Vondracek, J., van den Berg, M., Denison, M.S., Ringsted, T. and Andersson, P.L. (2014) In vitro and in silico derived relative effect potencies of Ah-receptor mediated effects by PCDD/Fs and PCBs in rat, mouse and guinea pig CALUX cell lines, Chem. Res. Toxicol. 27, 1120-1132. PMID: 24901989

Novotna, A., Korhonova, M., Bartonkova, I., Soshilov, A.A., Denison, M.S., Kolar, M. and Dvorak, Z. (2014) Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor, PLoS One 9(7) e101832. PMC4084896

Choi, S. H.; Kim, D.-S.; Kozukue, N.; Kim, H.-J.; Nishitani, Y.; Mizuno, M.; Levin, C. E.; Friedman, M., Protein, free amino acid, phenolic, ?-carotene, and lycopene content, and antioxidative and cancer cell inhibitory effects of 12 greenhouse-grown commercial cherry tomato varieties. J. Food Compos. Anal. 2014, 34, 115-127.

Friedman, M., Rice brans, rice bran oils, and rice hulls: composition, food and industrial uses, and bioactivities in humans, animals, and cells. J. Agric. Food Chem. 2013, 61, 10626–10641, ARIS no. 297371.

Friedman, M., Antibacterial, antiviral, and antifungal properties of wines and winery byproducts in relation to their flavonoid content. J. Agric. Food Chem. 2014, 62, 6025-6042.

Friedman, M., The chemistry and multi-beneficial bioactivities of carvacrol (4-isopropyl-2-methylphenol), a component of essential oils produced by aromatic plants and spices. J. Agric. Food Chem. 2014.

Kim, S. P.; Nam, S. H.; Friedman, M., Rice hull smoke extract protects mice against a Salmonella lipopolysaccharide-induced endotoxemia. J. Agric. Food Chem. 2014, 62, 7753-9.

Kim, S. P.; Park, S. O.; Lee, S. J.; Nam, S. H.; Friedman, M., A polysaccharide isolated from the liquid culture of Lentinus edodes (Shiitake) mushroom mycelia containing black rice bran protects mice against a Salmonella lipopolysaccharide-induced endotoxemia. J. Agric. Food Chem. 2013, 61, 10987-94.

Kim, S. P.; Park, S. O.; Lee, S. J.; Nam, S. H.; Friedman, M., A polysaccharide isolated from the liquid culture of Lentinus edodes (Shiitake) mushroom mycelia containing black rice bran protects mice against salmonellosis through up-regulation of the Th1 immune reaction. J. Agric. Food Chem. 2014, 62, 2384-91.

Nowotarska, S. W.; Nowotarski, K. I.; Friedman, M.; Situ, C., Effect of structure on the interactions between five natural antimicrobial compounds and phospholipids of bacterial cell membrane on model monolayers. Molecules 2014, 19, 7497-7515.

Rasooly, R.; Hernlem, B.; He, X.; Friedman, M., Microwave heating inactivates Shiga Toxin (Stx2) in reconstituted fat-free milk and adversely affects the nutritional value of cell culture medium. J. Agric. Food Chem. 2014, 62, 3301-3305.

Williams, J. R.; Rayburn, J. R.; Cline, G. R.; Sauterer, R.; Friedman, M., The potential protective effect of L-cysteine against the toxicity of acrylamide and furan in exposed Xenopus laevis embryos: an interaction study. J. Agric. Food Chem. 2014, 62, 7927-38.

Zhu, L.; Olsen, C.; McHugh, T.; Friedman, M.; Jaroni, D.; Ravishankar, S., Apple, carrot, and hibiscus edible films containing the plant antimicrobials carvacrol and cinnamaldehyde inactivate Salmonella Newport on organic leafy greens in sealed plastic bags. J. Food Sci. 2014, 79, M61-M66.

Walsh, H., J.J. Cheng, M.R. Guo. 2014 Effects of carbonation on probiotic survivability, physicochemical and sensory Properties of milk-based symbiotic beverages. J. Food Sci. M604-613.

Aumsuwan P, Khan SI, Khan IA, Avula B, Walker LA, Helferich WG, Katzenellenbogen BS, Dasmahapatra AK. Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells. In vitro Cell Dev Biol Anim. 2014 Aug 23 [Epub ahead of print] PMID: 25148825

Andrade, J.A., Lopez Cintron, J.R., Engeseth, J.J., Helferich, W.G. (2014). Development of a Point-of-Use Fortification Technology for Delivery of Micronutrients in Honduras. J Sci Food Agri. 2014 May 9. doi: 10.1002/jsfa.6736. [Epub ahead of print] PMID: 24817038.

Andrade, J., Ju, Y.H., Baker, C., Doerge, D.R. and Helferich, W.G. (2014). Long-term exposure to dietary sources of genistein induces estrogen-independence in the human breast cancer (MCF-7) xenograft model. Mol Nutr Food Res. 2014 Feb 24. doi: 10.1002/mnfr.201300780. [Epub ahead of print]. PMID: 24668689

Strakovsky, R.S., Lezmi, S., Flaws, J.A., Schantz, S.L., Pan, Y.X., Helferich, W.G. (2014). Genistein Exposure During the Early Postnatal Period Favors the Development of Obesity in Female, But Not Male Rats. Toxicol Sci. 2014 138:161-174. PMID: 24361872

Neese SL, Pisani SL, Doerge DR, Helferich WG, Sepehr E, Chittiboyina AG, Rottee SCK, Smillie TJ, Khan IA (2013) The effects of dietary treatment with S-equol on learning and memory processes in middle-aged ovariectomized rats. Neurotoxicol Teratol 2013 Dec 22. pii: S0892-0362(13)00226-2. doi: 10.1016/j.ntt.2013.12.004. [Epub ahead of print] PMID: 24368316

Jiang, Y., Gong, P., Madak-Erdogan, Z., Martin, T., Jeyakumar, M., Carlson, K., Khan, I., Smillie, T.J., Chittiboyina, A.G., Rotte, S.C.K., Helferich, W.G., Katzenellenbogen, J.A. and Katzenellenbogen, B.S. (2013). Mechanisms Enforcing the Estrogen Receptor ?-Selectivity of Botanical Estrogens. FASEB J. 27(11): 4406-4418. PMID: 23882126 PMCID:PMC3804744

Xing, H., Tang, L., Yang, X., Hwang, K., Wang, W., Yin, Q., Wong, N.Y., Dobrucki, L.W., Yasui, N., Katzenellenbogen, J.A., Helferich, W. Cheng, J., Lu, Y. (2013). Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo. J Mater Chem B Mater Biol Med. 1(39):5288-5297. PMID: 24159374

Yang, X., Belosay A., Hartman, J.A., Song H., Doerge D.R. and Helferich W.G. (2013). Estradiol increases ER-negative breast cancer metastasis in an experimental model. 2013. Clin Exp Metastasis. 30(6):711-721. PMID: 24096710

Sternberg RA, Pondenis HC, Yang X, Mitchell MA, O'Brien RT, Garrett LD, Helferich WG, Hoffmann WE, Fan TM. (2013). Association between Absolute Tumor Burden and Serum Bone-Specific Alkaline Phosphatase in Canine Appendicular Osteosarcoma. J Vet Intern Med. 27(4):955-963. PMID: 23734720

Turner, R.T., Iwaniec, U.T., Andrade, J., Branscum, A.J., Neese, S.L., Olson, D.A., Wagner, L., Wang, V.C., Schantz, S.L., Helferich, W.G. (2013). Genistein Administered as a Once-Daily Oral Supplement Had No Beneficial Effect on the Tibia in Rat Models for Postmenopausal Bone Loss. Menopause. 20(6):677-686. PMID: 23385720

Medina-Cleghorn D, Nomura DK. (2014) Exploring metabolic pathways and regulation through functional chemoproteomic and metabolomic platforms. Chemistry & Biology 21, 1171-1184. PMID: 25237861.

Cai X, Perttula K, Pajouh SK, Hubbard A, Nomura DK, Rappaport SM. (2014) Untargeted lipidomic profiling of human plasma reveals differences due to race, gender, and smoking status. Metabolomics: Open Access 4, 1000131.

Mulvihill MM, Nomura DK. (2014) Metabolomic Strategies to Map Functions of Metabolic Pathways. AJP Metabolism and Endocrinology 307, E237-E244. PMID: 24918200

Latimer LN, Lee MR, Medina-Cleghorn D, Kohnz RA, Nomura DK, Dueber JE. (2014) Employing a combinatorial expression approach to characterize xylose utilization in Saccharomyces cerevisiae. Metabolic Engineering 25, 20-29. PMID: 24930894.

Mulvihill MM, Benjamin DI, LeScolan E, Ji X, Shieh A, Green M, Narasimhalu T, Morris PJ, Luo K, Nomura DK. (2014) Metabolic Profiling Reveals PAFAH1B3 as a critical driver of breast cancer pathogenicity. Chemistry & Biology 21, 831-840. PMID: 24954006

Benjamin DI, Louie S, Mulvihill MM, Kohnz RA, Li DS, Chan LG, Sorrentino A, Bandhyopadhyay S, Cozzo A, Ohiri A, Goga A, Ng-SW, Nomura DK. (2014) INPP1 Promotes Cancer Aggressiveness by Linking Inositol Phosphate Recycling to Glycolytic and Lipid Metabolism. ACS Chemical Biology 20, 1340-1350. PMID: 24738946

Kohnz RK, Nomura DK. (2014) Chemical approaches to therapeutically target the metabolism and signaling of the endocannabinoid 2-AG and eicosanoids. Chemical Society Reviews 43, 6859-6869. PMID: 24676249

Morris PJ*, Medina-Cleghorn D*, Heslin A, King S, Orr J, Krauss RM, Nomura DK. (2014) Organophosphorus flame retardants inhibit specific liver carboxylesterases and cause serum hypertriglyceridemia. ACS Chemical Biology 9, 1097-1103. (*authors contributed equally to the work) PMID: 24597639

Hunerdosse D, Nomura DK. (2014) Activity-based proteomic and metabolomic approaches for understanding metabolism. Current Opinion in Biotechnology 28C, 116-126. PMID 24594637

Poole D, Lee M, Tso P, Bunnett N, Yo S, Lieu T, Shiu A, Wang J-C, Nomura DK, and Aponte GW. (2014) Feeding dependent activation of enteric cells and sensory neurons by lymphatic fluid: evidence for a neurolymphocrine system. AJP-Gastrointestinal and Liver Physiology 306, G686-G698. PMID: 24578341

Dominguez E, Galmozzi A, Chang JW, Hsu K-L, Pawlak J, Li W, Godio C, Thomas J, Partida D, Niessen S, O’Brien PE, Russell AP, Watt MJ, Nomura DK, Cravatt BF, Saez E. (2014) Integrated phenotypic screening and activity-based proteomics defines a role for carboxylesterase 3 in obesity and diabetes. Nature Chemical Biology 10, 113-121. PMID: 24362705

Medina-Cleghorn D, Heslin A, Morris PJ, Mulvihill MM, Nomura DK. (2014) Multidimensional profiling platforms reveal metabolic dysregulation caused by organophosphorus pesticides. ACS Chemical Biology 9, 423-432. PMID: 24205821

Nomura DK, Cravatt BF. (2013) Lipid Metabolism in Cancer. Biochimica et Biophysica Acta—Molecular and Cell Biology of Lipids 1831, 1497-1498. PMID: 23921253

Benjamin DI, Cozzo A, Ji X, Roberts LS, Louie SM, Luo K, Nomura DK. (2013) The ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids that fuel cancer pathogenicity. Proceedings of the National Academy of Sciences, USA 110, 14912-14917. PMID: 23980144

Louie SM*, Roberts LS*, Mulvihill MM, Luo K, Nomura DK. (2013) Cancer cells incorporate and remodel exogenous fatty acids into structural and oncogenic signaling lipids. Biochimica et Biophysica Acta—Molecular and Cell Biology of Lipids 1831, 1566-1572. PMID: 23872477 (* authors contributed equally to the work)

Louie SM, Roberts LS, Nomura DK. (2013) Mechanisms linking obesity and cancer. Biochimica et Biophysica Acta—Molecular and Cell Biology of Lipids 1831, 1499-1508. PMID: 23470257

Medina-Cleghorn D, Nomura DK. (2013) Chemical Approaches to Study Metabolic Networks. Pflugers Archive 465,427-440. PMID: 23296751

Cao Z, Mulvihill MM, Mukhopadhyay P, Xu H, Erdelyi K, Hao E, Holovac E, Hasko G, Cravatt BF,

Nomura DK#, Pal Pacher#. (2013) Monoacylglycerol lipase controls endocannabinoid and eicosanoid signaling and hepatic injury in mice. Gastroenterology 144, 808-817. PMID: 23295443 (# co-corresponding authors)

Mulvihill MM, Nomura DK. (2013) Therapeutic Potential of Monoacylglycerol Lipase Inhibitors. Life Sciences 92, 492-497. PMID: 23142242

Kumar M, Roe K, Nerurkar PV, Orillo B, Thompson KS, Verma S and Nerurkar VR. Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus. J Neuroinflammation. 2014 11:80. PMID: 24750819

Rajamoorthi A, Shrivastava S, Steele R, Nerurkar P, Gonzalez JG, Crawford S, Varvares M, Ray RB. Bitter melon reduces head and neck squamous cell carcinoma growth by targeting c-Met signaling. PLoS One. 2013 8(10):e78006. PMID: 24750819

Rensvold JW, Ong SE, Jeevananthan A, Carr SA, Mootha VK and Pagliarini DJ. Complementary RNA and Protein Profiling Identifies Iron as a Key Regulator of Mitochondrial Biogenesis. Cell Reports, 2013, 3(1): 237-245

Baldwin TT, Zitomer NC, Mitchell TR, Zimeri A-M, Bacon CW, Riley RT and Glenn AE. Seedling blight of maize by Fusarium verticillioides causes accumulation of fumonisin B1 in upper leaves apart from colonization of the leaves. Journal of Agricultural and Food Chemistry, 62: 2118-2125, 2014.

Riley RT. Naturally Occurring Chemical Carcinogens. In: World Cancer Report 2014, pp. 206-219, B. Stewart and C.P. Wild, eds., International Agency for Research on Cancer, Lyon, France, 2014.

Torres O, Matute J, Gelineau-van Waes J, Maddox JR, Gregory SG, Ashley-Koch AE, Showker JL, Voss KA, and Riley RT. Human health implications from co-exposure to aflatoxins and fumonisins in maize-based foods in the Latin America: Guatemala a case study. World Mycotoxin Journal DOI 10.3920/WMJ2014.1736.

Torres O, Matute J, Gelineau-van Waes J,. Maddox JR,. Gregory SG,. Ashley-Koch AE, Showker JL, Zitomer NC, Voss KA, Riley RT. Urinary fumonisin B1 and estimated fumonisin intake in women from high and low exposure communities in Guatemala. Mol. Nutr. Food Res. 58:973-983, 2014.

Voss KA and Riley RT. Fumonisin toxicity and mechanism of action: overview and current perspectives. Food Safety (Japan) 1:49-69, 2013.

Voss KA, Riley RT, Gelineau-van Waes J. Fumonisin ¬B1-induced neural tube defects were not increased in LM/Bc mice fed folate deficient diets. Mol. Nutr. Food Res.58:1190-1198, 2014.

Cho, Y., N.D. Turner, L.A. Davidson, R.S. Chapkin, R.J. Carroll, and J.R. Lupton. 2014. Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid DHA and butyrate through promoter methylation. Experimental Biology and Medicine 239:302-310. PMID: 24495951.

Morgan, J.L.L., L.E. Ritchie, B.E. Crucian, C. Theriot, H. Wu, S.M. Smith, N.D. Turner, and S.R. Zwart. 2014. Increased dietary iron and radiation in rats promotes oxidative stress, localized and systemic immune system responses, and alters colon mucosal environment. FASEB Journal 28:1486-1498. PMID: 24334706

Wang, R., Löhr, C.V., Fischer, K., Dashwood, W.M., Greenwood, J.A., Ho, E., Williams, D.E., Ashktorab, H., Dashwood, M.R. and Dashwood, R.H. (2013) Epigenetic Inactivation of Endothelin-2 and Endothelin-3 in Colon Cancer. Internatl. J. Cancer 132:1004-1012.

Rajendran, P., Kidane, A.I., Yu, T.-W., Dashwood, W.-M., Bisson, W.H., Löhr, C.V., Ho, E., Williams, D.E. and Dashwood, R.H. (2013) HDAC Turnover, CtIP Acetylation and Dysregulated DNA Damage in Colon Cancer Cells Treated With Sulforaphane and Related Dietary Isothiocyanates. Epigenetics 8:612-623.

Wong, C.P., Hsu, A., Buchanan, A., Palomera-Sanchez, Z., Beaver, L.M., Houseman, E.A., Williams, D.E., Dashwood, R.H. and Ho, E. (2014) Effects of Sulforaphane and 3,3'-Diindolylmethane on Genome-Wide Promoter Methylation in Normal Prostate Epithelial Cells and Prostate Cancer Cells. PLoS One 9:e86787.

Crowell, S.R., Hanson-Dury, S., Williams, D.E. and Corley, R.A. (2014) In Vitro Metabolism of Benzo[a]pyrene and Dibenzo[def,p]chrysene in Rodent and Human Hepatic Microsomes. Toxicol. Lett. 228:48-55.

Beaver, L.M., Buchanan, A., Sokolowski, E.I., Riscoe, A.N., Wong, C.P., Chang, J.H., Löhr, C.V., Williams, D.E., Dashwood, R.H. and Ho, E. (2014) Transcriptome Analysis Reveals a Dynamic and Differential Transcriptional Response to Sulforaphane in Normal and Prostate Cancer Cells and Suggests a Role for Sp1 in Chemoprevention. Molec. Nutr. Food Res. Doi: 10.1002/mnfr.2014002689

Yang, G., H. Wang, Y. Kang, and M. J. Zhu. (2014). Grape seed extract improves epithelial structure and suppresses inflammation in the ileum of Il10-deficient Mice. Food and Function, 5: 2558-2563

Wang, B., G. Yang, X. Liang, M. J. Zhu, and M. Du. (2014). Grape seed extract prevents skeletal muscle wasting in Interleukin 10 knockout mice. BMC Complementary and Alternative Medicine, 14:162-169.

Zhang, H., Y. Xue, H. Wang, Y. Huang, M. Du, and M. J. Zhu. (2014). Mast cell deficiency induces inflammation and exacerbates inflammatory bowel symptoms in Il10-deficiency mice. World Journal of Gastroenterology, 20:9106-9115

Wang, H., Y. Xue, B. Wang, J. Zhao, X. Yan, Y. Huang, M. Du, and M. J. Zhu. (2014). Maternal obesity exacerbates insulitis and type I diabetes in NOD mice. Reproduction, 148:73-79.

Xue, Y., H. Wang, M. Du, and M. J. Zhu. (2014). Maternal obesity induces gut inflammation and impairs gut epithelial barrier function in NOD mice. Journal of Nutritional Biochemistry, 25: 758-764.

Xue, Y., H. Zhang, H. Wang, J. Hu, M. Du, and M. J. Zhu. (2014). Host inflammatory response inhibits Escherichia coli O157:H7 adhesion to gut epithelium through augmenting mucin expression. Infection and Immunity, 82:1921-1930.

Zhu, M. J., M. Du, and S.P. Ford. (2014). Impacts of maternal obesity on placental and gut inflammation and health. An invited review. Journal of Animal Science, 92:1840-1849.

Kandadi, M. R., Y. Hua, M. J. Zhu, S. Turdi, P.W. Nathanielsz, S. P. Ford, and S. Nair. (2013). Influence of gestational overfeeding and obesity on myocardial pro-inflammatory mediators in fetal sheep heart. Journal of Nutritional Biochemistry, 24:1982-1990

Wang, H., Y. Xue, H. Zhang, Y. Huang, G Yang, M. Du, and M. J. Zhu. (2013). Dietary grape seed extract ameliorates symptoms of inflammatory bowel disease in interleukin-10 deficient mice. Molecular Nutrition & Food Research, 57:2253-2257.

Yang, Q. Y., J .F. Liang, C. J. Rogers, J. X. Zhao, M. J. Zhu, and M. Du. (2013). Maternal obesity induces epigenetic modifications to facilitate Zfp423 expression and enhance adipogenic differentiation in fetal mice. Diabetes, 62:3727-3735.

12/10/2015

1. Anderson, S. N., Richards, J. M., Esquer, H. J., Benninghoff, A. D., Arif, A. M., and Berreau, L. M. (2015). A Structurally-Tunable 3-Hydroxyflavone Motif for Visible Light-Induced Carbon Monoxide-Releasing Molecules (CORMs). ChemistryOpen 4, 590-594.


2. Andrade, J. E., Ju, Y. H., Baker, C., Doerge, D. R., and Helferich, W. G. (2015). Long-term exposure to dietary sources of genistein induces estrogen-independence in the human breast cancer (MCF-7) xenograft model. Mol Nutr Food Res 59, 413-423.


3. Andrade, J. E., Rosales, E., Lopez, J. R., Carrillo, E. P., Engeseth, N. J., and Helferich, W. G. (2015). Development of a point-of-use fortification technology for delivery of micronutrients in Honduras. J. Sci. Food Agric. 95, 393-400.


4. Andruska, N. D., Zheng, X., Yang, X., Mao, C., Cherian, M. M., Mahapatra, L., Helferich, W. G., and Shapiro, D. J. (2015). Estrogen receptor alpha inhibitor activates the unfolded protein response, blocks protein synthesis, and induces tumor regression. Proc. Natl. Acad. Sci. U. S. A. 112, 4737-4742.


5. Andruska, N., Zheng, X., Yang, X., Helferich, W. G., and Shapiro, D. J. (2015). Anticipatory estrogen activation of the unfolded protein response is linked to cell proliferation and poor survival in estrogen receptor alpha-positive breast cancer. Oncogene 34, 3760-3769.


6. Atwell, L.L., Beaver, L.M., Shannon, J., Williams, D. E., Dashwood, R.H. and Ho, E. (2015) Epigenetic Regulation by Sulforaphane: Opportunities for Breast and Prostate Cancer Chemoprevention. Current Pharmacol. Reports. 1:102-111.


7. Atwell, L.L., Hsu, A., Wong, C.P., Stevens, J.F., Bella, D., Yu, T.., Pereira, C.B., Löhr, C.V., Christensen, J.M., Dashwood, R.H., Williams, D.E., Shannon, J. and Ho, E. (2014) Absorption and Chemopreventive Targets of Sulforaphane in Humans Following Consumption of Broccoli Sprouts or Myrosinase-Treated Broccoli Sprout Extracts. Molec. Nutr. Food Res. 59:424-433.


8. Aumsuwan, P., Khan, S. I., Khan, I. A., Avula, B., Walker, L. A., Helferich, W. G., Katzenellenbogen, B. S., and Dasmahapatra, A. K. (2015). Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells. In Vitro Cell. Dev. Biol. Anim. 51, 59-71.


9. Bates, M.A., Brandenberger, C., Langohr, I., Kumagai, K., Harkema, J.R., Holian, A., Pestka, J.J., 2015. Silica Triggers inflammation and ectopic lymphoid neogenesis in the lungs in parallel with accelerated onset of systemic autoimmunity and glomerulonephritis in the lupus-prone NZBWF1 mouse. PLoS ONE 10, e0125481.


10. Bello NT 2015 Clinical utility of guanfacine extended release in the treatment of ADHD in children and adolescents. Patient Prefer Adherence 9:877-885


11. Bello NT, Walters AL, Verpeut JL, Caverly J 2014 Dietary-induced binge eating increases prefrontal cortex neural activation to restraint stress and increases binge food consumption following chronic guanfacine. Pharmacol Biochem Behav 125:21-28


12. Bello NT, Yeh CY, Verpeut JL, Walters AL 2014 Binge-like eating attenuates nisoxetine feeding suppression, stress activation, and brain norepinephrine activity. PLoS One 9:e93610


13. Benninghoff, A.D., Lefevre, M., Hintze, K.J., Ward, R.E. and Broadbent, J.R. (2015)  Fighting cancer with functional foods: new approaches to investigate the interactions of dietary bioactive chemicals and the gut microbiome.  Journal of Developments in Sustainable Agriculture 10: 1-21.


14. Bittner, G.D., Denison, M.S., Yang, C.S., Stoner, M.A. and He, G. (2014) Chemicals having estrogenic activity can be released from some bisphenol A-free, hard and clear, thermoplastic resins, Environ. Health 14 (1), 103.


15. Block, K. I., . . . . Helferich, W. G., et al. (2015). Designing a broad-spectrum integrative approach for cancer prevention and treatment. Semin. Cancer Biol. 35 Suppl, S276-304.


16. Boonmuen, N., Gong, P., Ali, Z., Chittiboyina, A. G., Khan, I., Doerge, D. R., Helferich, W. G., Carlson, K. E., Martin, T., Piyachaturawat, P., Katzenellenbogen, J. A., and Katzenellenbogen, B. S. (2015). Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities. Steroids.


17. Brennan, J. C., Bassal, A., He, G. and Denison, M.S. (2015) Development of a recombinant human ovarian (BG1) cell line containing estrogen receptor a and b for improved detection of estrogenic/antiestrogenic chemicals, Environ. Toxicol. Chem., In Press.


18. Brennan, J. C., He, G., Tsutsumi, T., Zhao, J., Wirth, E., Fulton, M. H. and Denison, M.S. (2015) Development of species-specific Ah receptor-responsive third generation CALUX cell lines with increased sensitivity and responsiveness, Environ. Sci. Tech. 49(19):11903-12.


19. Caron-Beaudoin, E., Denison, M. S. and Sanderson, J. T. (2015) Effects of neonicotinoids on promoter-specific expression and activity of aromatase in human adrenocortical carcinoma (H295R) and umbilical vein endothelial (HUVEC) cells, Toxicol. Sci., In Press.


20. Casey, S. C., Amedei, A., Aquilano, K., Azmi, A. S., Benencia, F., Bhakta, D., Bilsland, A. E., Boosani, C. S., Chen, S., Ciriolo, M. R., Crawford, S., Fujii, H., Georgakilas, A. G., Guha, G., Halicka, D., Helferich, W. G., Heneberg, P., Honoki, K., Keith, W. N., Kerkar, S. P., Mohammed, S. I., Niccolai, E., Nowsheen, S., Vasantha Rupasinghe, H. P., Samadi, A., Singh, N., Talib, W. H., Venkateswaran, V., Whelan, R. L., Yang, X., and Felsher, D. W. (2015). Cancer prevention and therapy through the modulation of the tumor microenvironment. Semin. Cancer Biol. 35 Suppl, S199-223.


21. Chieng, M., Ying, S., Kunde, D., Cook, A., Nerurkar, P.V., Ahuja, K. and Eri, R. Bitter melon extract protects against ER stress in LS174T colonic epithelial cells and copper-induced oxidation in human serum. Phytotherapy Research. Under revision, 2015


22. Chung, J., Anderson, S.A., Gwynn, B, Deck, K.M., Chen, M.J., Langer, N.B., Shaw, G.C., Huston, N.C., Boyer, L.F., Datta, S., Paradkar, P.N., Li, L., Wei, Z., Lambert, A.J., Sahr, K., Wittig, J.G., Chen, W., Lu, W., Galy, B., Schlaeger, T.M., Hentze, M.W., Ward, D.M., Kaplan, J., Eisenstein, R.S., Peters, L.L., Paw, B.H. (2014) Iron regulatory protein 1 protects against mitoferrin-I deficient porphyria. J. Biol. Chem. 289:7835. PMC3953295.


23. Chung, J., Bauer, D.E., Ghamari, A., Nizzi, C.P., Deck, K.M., Kingsley, P.D., Yuen, Y.Y., Huston, N.C., Chen, C., Schultz, I.J., Dalton, A.J., Wittig, J.G., Palis, J., Orkin, S.H., Lodish, H.F., Eisenstein, R.S., Cantor, A.B. and Paw, B.H. (2014) The mTORC/4E-BP pathway coordinately regulates hemoglobin production with L-leucine availability. Sci Signal. 2015 8(372):ra34. PMC4402725.


24. Coulombe, R.A., Bergeson, J., Aguilar, S., Hergert, N., and Lefevre, M. (2014) Effects of Ambient Particulate Air Pollution on Pulmonary Function, Pulmonary and Systemic Inflammation, and Lack Protective Effect of a Comprehensive Antioxidant and Anti-Inflammatory Dietary Supplement. PLOS One (in press).


25. Cox-York K, Sheflin AM, Foster MT, Gentile CL, Kahl A, Koch L, Britton S, Weir TL (2015) Gut ecology associated with high innate aerobic capacity protects against ovariectomy-induced cardiometabolic risk. Physiol Reports 3, e12488 .


26. Croes, K., Debaille, P., Van den Bril, B., Staelens, J., Vandermarken, T., Van Langenhove, K., Denison, M.S., Leermakers, M. and Elskens, M. (2015) Assessment of estrogenic activity in PM₁₀ air samples with the ERE-CALUX bioassay: method optimization and implementation at an urban location in Flanders (Belgium), Chemosphere 144, 392-398.


27. Davis, A. P., Benninghoff, A. D., Thomas, A. J., Sessions, B. R., and White, K. L. (2015). DNA methylation of the LIN28 pseudogene family. BMC Genomics 16, 287.


28. DeGroot, D.E., Franks, D.G., Higa, T., Tanaka, J., Hahn, M.E. and Denison, M.S. (2015) Naturally-occurring marine brominated indoles are aryl hydrocarbon receptor ligands/agonists, Chem. Res. Toxicol. 28, 1176-1185.


29. Ferguson, L. R., Chen, H., Collins, A. R., Connell, M., Damia, G., Dasgupta, S., Malhotra, M., Meeker, A. K., Amedei, A., Amin, A., Ashraf, S. S., Aquilano, K., Azmi, A. S., Bhakta, D., Bilsland, A., Boosani, C. S., Chen, S., Ciriolo, M. R., Fujii, H., Guha, G., Halicka, D., Helferich, W. G., Keith, W. N., Mohammed, S. I., Niccolai, E., Yang, X., Honoki, K., Parslow, V. R., Prakash, S., Rezazadeh, S., Shackelford, R. E., Sidransky, D., Tran, P. T., Yang, E. S., and Maxwell, C. A. (2015). Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition. Semin. Cancer Biol. 35 Suppl, S5-S24.


30. Gentile CL, Weir TL , Cox-York K , Yuren W, Wang D, Reese L, Moran G, Estrada A, Mulligan C, Pagliassotti M, Foster MT (2014) The Role of Visceral and Subcutaneous Adipose Tissue Fatty Acid Composition in Liver Pathophysiology Associated with NALFD. Adipocyte, doi=10.4161/21623945.2014.978662


31. Hintze, K.J, Cox, J.E., Rompato, G., Benninghoff, A.D., Ward, R.E., Broadbent, J., and Lefevre, M. (2014)  Broad scope method for creating humanized animal models for animal health and disease research through antibiotic treatment and human fecal transfer.  Gut Microbes 5(2): 1-9


32. Hong, M.Y., N.D. Turner, M.E. Murphy, R.J. Carroll, R.S. Chapkin, and J.R. Lupton.  In vivo regulation of colon cell proliferation, differentiation, apoptosis and P27Kip1 by dietary fish oil and butyrate in rats.  Cancer Prevention Research (In Press).


33. Jiang, W. G., Sanders, A. J., Katoh, M., Ungefroren, H., Gieseler, F., Prince, M., Thompson, S. K., Zollo, M., Spano, D., Dhawan, P., Sliva, D., Subbarayan, P. R., Sarkar, M., Honoki, K., Fujii, H., Georgakilas, A. G., Amedei, A., Niccolai, E., Amin, A., Ashraf, S. S., Ye, L., Helferich, W. G., Yang, X., Boosani, C. S., Guha, G., Ciriolo, M. R., Aquilano, K., Chen, S., Azmi, A. S., Keith, W. N., Bilsland, A., Bhakta, D., Halicka, D., Nowsheen, S., Pantano, F., and Santini, D. (2015). Tissue invasion and metastasis: Molecular, biological and clinical perspectives. Semin. Cancer Biol. 35 Suppl, S244-275.


34. Johnson, N.B., Deck, K.M., Nizzi, C.P. and Eisenstein, R.S. Interrelationships Between Iron-Sulfur Cluster Biogenesis and Control of Iron Metabolism by Iron Regulatory Protein 1 and the E3 Ubiquitin Ligase FBXL5. In preparation.


35. Kang, Y., Nian, H., Rajendran, P., Kim, E., Dashwood, W.M., Pinto, J., Boardman, L., Thibodeau, S., Limburg, P., Löhr, C., Bisson, W., Williams, D.E., Ho, E. and Dashwood, R.H. (2014) HDAC8 and STAT3 Repress BMF Gene Activity in Colon Cancer Cells. Cell Death Dis. 5:e1476.


36. Kelly CJ, Zheng L, Campbell EL, Saeedi B, Scholz CC, Bayless AJ, Wilson KE, Glover LE, Kominsky DJ, Magnuson AM, Weir TL, Ehrentraut SE, Nguyen V, Taylor CT, Colgan SP (2015) Host-Microbe Crosstalk between Short-Chain Fatty Acids and Intestinal Epithelial HIF Provides a New Mechanism to Augment Tissue Barrier Function. Cell Host & Microbe DOI: http://dx.doi.org/10.1016/j.chom.2015.03.005.


37. Khedidji, S., Croes, K., Yassaa, N., Ladji, R., Denison, M.S., Baeyens, W. and Elskens, M. (2015) Assessment of dioxin-like activity in PM₁₀ air samples from an industrial location in Algeria, using the DRE-CALUX bioassay, Environ. Sci. Poll. Res., In Press.


38. Kim, E., Bisson ,W.H., Löhr, C.V., Williams, D.E., Ho, E., Dashwood, R.H. and Rajendran, P. (2015) Histone and Non-Histone Targets of Dietary Deacethylase Inhibitors. Curr. Topics Med. Chem., in press.


39. Kim, E., L.A. Davidson, R.S. Zoh, B.S. Patil, G.K. Jayaprakasha, E.S. Callaway, C.D. Allred, N.D. Turner, and R.S. Chapkin.  Homeostatic responses of colonic LGR5 stem cells following acute in vivo exposure to a genotoxic carcinogen.  Carcinogenesis (Accepted with revision).


40. Liu, Y., Hilakivi-Clarke, L., Zhang, Y., Wang, X., Pan, Y. X., Xuan, J., Fleck, S. C., Doerge, D. R., and Helferich, W. G. (2015). Isoflavones in soy flour diet have different effects on whole-genome expression patterns than purified isoflavone mix in human MCF-7 breast tumors in ovariectomized athymic nude mice. Mol Nutr Food Res 59, 1419-1430.


41. Maayah, Z.H., Ghebeh, H.B., Alhaider, A.A., El-Kadi, A.O., Soshilov, A.A., Denison, M.S., Ansari, M.A. and Korashy, H.M. (2015) Metformin inhibits 2,7-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway, Toxicol. Appl. Pharmacol. 284, 217-226. 


42. Madak-Erdogan, Z., Gong, P., Zhao, Y. C., Xu, L., Wrobel, K. U., Hartman, J. A., Wang, M., Cam, A., Iwaniec, U. T., Turner, R. T., Twaddle, N. C., Doerge, D. R., Khan, I. A., Katzenellenbogen, J. A., Katzenellenbogen, B. S., and Helferich, W. G. (2015). Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland. Mol Nutr Food Res.


43. Madeen, E., Corley, R.A., Crowell, S., Turteltaub, K., Ognibene, T., Malafatti, M., McQuistan, T.J., Garrard, M., Sudakin, D. and Williams, D.E. (2014) Human In Vivo Pharmacokinetics of [¹⁴C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral


44. Mexia, N., Gaitanis, G., Velegraki, A., Soshilov, A., Denison, M.S. and Magiatis, P. (2015) Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast, Arch. Biochem. Biophys. 571, 16-20.


45. Mohammad, R. M., Muqbil, I., Lowe, L., Yedjou, C., Hsu, H. Y., Lin, L. T., Siegelin, M. D., Fimognari, C., Kumar, N. B., Dou, Q. P., Yang, H., Samadi, A. K., Russo, G. L., Spagnuolo, C., Ray, S. K., Chakrabarti, M., Morre, J. D., Coley, H. M., Honoki, K., Fujii, H., Georgakilas, A. G., Amedei, A., Niccolai, E., Amin, A., Ashraf, S. S., Helferich, W. G., Yang, X., Boosani, C. S., Guha, G., Bhakta, D., Ciriolo, M. R., Aquilano, K., Chen, S., Mohammed, S. I., Keith, W. N., Bilsland, A., Halicka, D., Nowsheen, S., and Azmi, A. S. (2015). Broad targeting of resistance to apoptosis in cancer. Semin. Cancer Biol. 35 Suppl, S78-S103.


46. Monson, M. S., Coulombe, R.A., and K.M. Reed. (2015). Sensitivity and Response of Poultry to Aflatoxin B₁ Exposure. Agriculture   doi:10.3390/agriculture50x000x (in press).


47. Monson, M. S., Settlage, R.E., McMahon, K.W., Mendoza, K.M., Rawal, S., El-Nezami, H., Coulombe, R.A., and K.M. Reed. (2014) Response of the Hepatic Transcriptome to Aflatoxin B₁ in Domestic Turkey. PLOS One June 30;9(6): doi: 10.1371/journal.pone.0100930. 


48. Monson, M. S., Settlage, R.E., Mendoza, K.M., Rawal, S., El-Nezami, H., Coulombe, R.A., and K.M. Reed. (2015). Modulation of the Spleen Transcriptome in Domestic Turkey (Meleagris gallopavo) in Response to Aflatoxin B1 and Probiotics. Immunogenetics Jan 20; DOI 10.1007/s00251-014-0825-y


49. Neale, P., Ait-Aissa, S., Brack, W., Creusot, N., Denison, M.S., Deutschmann, B., Hilscherova, K., Hollert, H., Krauss, M., Novak, J., Schulze, T., Seiler, T.-B., Serra, H., Shao, Y. and Escher, B. (2015) Linking in vitro effects and detected organic micropollutants in surface water using mixture toxicity modeling, Environ. Sci. Tech., In Press.


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Brennan, J.C., Bassal, A., He, G. and Denison, M.S., 2016. Development of a recombinant human ovarian (BG1) cell line containing estrogen receptor a and b for improved detection of estrogenic/antiestrogenic chemicals. Environ. Toxicol. Chem. 35, 91-100. PMC4772679

Brown, D.G., Rao, S., Weir, T.L., O’Malia, J., Bazan, M., Brown, R.J., Ryan, E.P., 2016. Metabolomics investigation of tumors, adjacent colonic mucosa and stool from colorectal cancer patients. Cancer & Metabolism 4:11.

Cai, K, Yen, J, Yin, Q, Liu, Y, Song, Z, Lezmi, S, Zhang, Y, Yang, X, Helferich, WG, and Cheng, J., 2015. Redox-responsive self-assembled chain-shattering polymeric therapeutics. Biomater Sci. 3, 1061-1065. PMID: 26146551

Casey, SC, Amedei, A, Aquilano, K, Benencia, F, Bhakta, D, Boosani, CS, Chen, S, Ciriolo, MR, Crawford, S, Fujii, H, Georgakilas, AG, Guha, G, Halicka, D, Helferich, WG, Heneberg, P, Honoki, K, Kerkar, SP, Mohammed, SI, Niccolai, E, Nowsheen, S, Vasantha Rupasinghe, HP, Samadi, A, Singh, N, Talib, WH, Venkateswaran, V, Whelan, RL, Yang, X, Felsher, DW., 2015. Cancer prevention and therapy through the modulation of the tumor microenvironment. Semin Cancer Biol. Apr 9. pii: S1044-579X(15)00015-2. doi: 10.1016/j.semcancer.2015.02.007. [Epub ahead of print] Review. PMID: 25865775.

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Choi, S.-H., Kozukue, N., Kim, H.-J., and Friedman, M., 2016. Analysis of protein amino acids, non-protein amino acids and metabolites, dietary protein, glucose, fructose, sucrose, phenolic, and flavonoid content and antioxidative properties of potato tubers, peels, and cortexes (pulps). J. Food Compos. Anal. 50, 77-87.

Clark, E.S., Flannery, B.M., Gardner, E.M., Pestka, J.J., 2015a. High sensitivity of aged mice to deoxynivalenol (Vomitoxin)-induced anorexia corresponds to elevated proinflammatory cytokine and satiety hormone responses. Toxins (Basel) 7, 4199-4215.

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Cole, B., Brander, S., Jeffries, K., Hasenbein, S., He, G., Denison, M.S., Fangue, N. and Connon, R., 2016. Changes in menidia beryllina gene expression and in vitro hormone receptor activation following exposure to estuarine waters near treated wastewater outfalls, Arch. Environ. Contam. Toxicol. 71, 210-223. PMID: 27155869

Corrada, D., Soshilov, A.A., Denison, M.S. and Bonati, L., 2016. Deciphering dimerization modes of PAS domains: Computational and experimental analyses of the AhR:ARNT complex reveal new insights into the mechanisms of AhR transformation, PLoS Comp. Biol. 12(6), e1004981. PMC4905635

Cox-York, K, Sheflin, AM, Foster, MT, Gentile, CL, Kahl, A, Koch, L, Britton, S, Weir, TL, 2015. Gut ecology associated with high innate aerobic capacity protects against ovariectomy-induced cardiometabolic risk. Physiol Reports 3, e12488.

Croes, K., Van den Heuvel, R., Van den Bril, B., Staelens, J., Denison, M.S., Van Langenhove, K., Vandermarken, T. and Elskens, M., 2016. Assessment of estrogenic and androgenic activity in PM10 air samples from an urban, industrial and rural area in Flanders (Belgium) using the CALUX bioassay. Environ Res. 150, 66-72. PMID: 27257826

Doerge, DR, Woodling, KA, Churchwell, MI, Fleck, SC, and Helferich, WG., 2016. Pharmacokinetics of isoflavones from soy infant formula in neonatal and adult rhesus monkeys. Food Chem Toxicol. Apr 12. pii: S0278-6915(16)30111-9. doi: 10.1016/j.fct.2016.04.005. [Epub ahead of print] PMID:27084109

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Downing, L.E., Ferguson, B.S., Rodriguez, K., Ricketts, M.L., 2016. A grape seed procyanidin extract inhibits HDAC activity leading to increased Pparα phosphorylation and target-gene expression. Mol Nutr Food Res. Sep 14. doi: 10.1002/mnfr.201600347. [Epub ahead of print] PMID: 27624175

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Foster, M.T., Gentile, C.L., Cox-York, K., Wei, Y., Wang, D., Estrada, A., Reese, L., Miller, T., Pagliassotti, M.J., Weir, T.L., 2016. Fuzhuan tea consumption imparts hepatoprotective effects and alters intestinal microbiota in high saturated fat diet-fed rats. Molecular Nutrition and Food Research 60, 1213-1220.

Friedman, M., 2016. Bioactive compounds from Ziziphus jujuba and allied species. In Chinese Dates: A Traditional Functional Food, Liu, D.; Ye, X.; Jiang, Y., Eds. CRC Press: Boca Raton, FL, pp 35-52.

Friedman, M., and Levin, C.E., 2016. Glycoalkaloids and calystegine alkaloids in potatoes. In Advances in Potato Chemistry and Technology, 2nd ed.; Singh, J.; Kaur, L., Eds. Elsevier: Oxford, UK, pp 167-194.

Friedman, M., Levin, C.E., and Henika, P.R., 2016. Addition of phytochemical-rich plant extracts mitigate the antimicrobial activity of essential oil/wine mixtures against Escherichia coli O157:H7 but not against Salmonella enterica. Food Control Online Sept 4, doi: 10.1016/j.foodcont.2016.09.002.

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Heidker, R.M., Caiozzi, G.C., Ricketts, M.L., 2016. Dietary procyanidins selectively modulate intestinal farnesoid X receptor-regulated gene expression to alter enterohepatic bile acid recirculation: elucidation of a novel mechanism to reduce triglyceridemia. Mol Nutr Food Res. 60, 727-36. doi: 10.1002/mnfr.201500795. PMID: 26718753

Heidker, R.M., Caiozzi, G.C., Ricketts, M.L., 2016. Grape seed procyanidins and cholestyramine differentially alter bile acid and cholesterol homeostatic gene expression in mouse intestine and liver. PLoS One. 11(4):e0154305. doi: 10.1371/journal.pone.0154305. PMID: 27111442

Hong, M.Y., Turner, N.D., Murphy, M.E., Carroll, R.J., Chapkin, R.S., and Lupton, J.R., 2015. In vivo regulation of colon cell proliferation, differentiation, apoptosis and P27Kip1 by dietary fish oil and butyrate in rats. Cancer Prevention Research 8, 1076-1083. PMID 26323483.

Hwang, P., Oishi, M., Karratti-Abordo, J., and Nerurkar, P.V., Fermented noni juice induces apoptosis by differentially regulating survivin signaling in ER positive, MCF-7 and triple negative, MDA-MB-231 breast cancer cells. Oncotarget, Submitted, 2016

Jiang, WG, Sanders, AJ, Katoh, M, Ungefroren, H, Gieseler, F, Prince, M, Thompson, SK, Zollo, M, Spano, D, Dhawan, P, Silva, D, Subbarayan, PR, Sarkar, M, Honoki, K, Fujii, H, Georgakilas, AG, Amedei, A, Niccolai, E, Amin, A, Ashraf, SS, Ye, L, Helferich, WG, Yang, X, Boosani, CS, Guha, G, Ciriolo, MR, Aquilano, K, Chen, S, Azmi, AS, Keith, WN, Bilsland, A, Bhakta, D, Halicka, D, Nowsheen, S, Pantano, F, Santini, D., 2015. Tissue invasion and metastasis: Molecular, biological and clinical perspectives. Semin Cancer Biol. Apr 9. pii: S1044-579X(15)00023-1. doi: 10.1016/j.semcancer.2015.03.008. [Epub ahead of print] Review. PMID: 25865774.

Johnson, G.S., Li, J., Beaver, L., Dashwood, W.-M., Sun, D., Rajendran, P., Williams, D.E., Ho, E. and Dashwood, R.H., 2016. A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a co-activator of NQO1 in sulforaphane-treated colon cancer cells. Molec. Nutr. Food Res., in press.

Johnson, N.B., Deck, K.M., Nizzi, C.P. and Eisenstein, R.S. A synergistic role of IRP1 and FBXL5 in controlling iron metabolism during cell proliferation. To be submitted 11/16.

Joshi, K., Parks, P., Ravishankar, S., and Friedman, M., 2016. The impact of plant-based antimicrobials on sensory properties of organic leafy greens. Food Nutr. Sci. 7, 906-919.

Juneja, V.K., Cadavez, V., Gonzales-Barron, U., Mukhopadhyay, S. and Friedman, M., 2016. Effect of pomegranate powder on the heat inactivation of Escherichia coli O104:H4 in ground chicken. Food Control 70, 26-34.

Kang, Y., Xue, Y., Du, M., Zhu, M.J., 2016. Preventative effects of Goji berry in dextran sulfate sodium-induced colitis. Journal of Nutritional Biochemistry, accepted.

Kim, E., Davidson, L.A., Zoh, R.S., Patil, B.S., Jayaprakasha, G.K., Callaway, E.S., Allred, C.D., Turner, N.D., and Chapkin, R.S., 2016. Homeostatic responses of colonic LGR5 stem cells following acute in vivo exposure to a genotoxic carcinogen. Carcinogenesis 37, 206-214.

Kim, E., Davidson, L.A., Zoh, R.S., Hensel, M.E., Salinas, M.L., Patil, B.S., Jayaprakasha, G.K., Callaway, E.S., Allred, C.D., Turner, N.D., Weeks, B., and Chapkin, R.S., 2016. Rapidly cycling Lgr5+ stem cells are exquisitely sensitive to extrinsic dietary factors that modulate colon cancer risk. Cell Death & Disease 7, e2460: doi:10.1038/cddis.2016.269.

Kim, S.-P., Lee, S.-J., Nam, S.-H., and Friedman, M., 2016. Elm tree (Ulmus parvifolia) bark bioprocessed with mycelia of Shiitake (Lentinus edodes) mushrooms in liquid culture: composition and mechanism of protection against allergic asthma in mice. J. Agric. Food Chem. 64, 773-84.

Kunde, D., Chong, W., Nerurkar, P., Ahuja, K., Just, J., Smith, J., Guven, N., and Eri, R. Bitter melon protects against ER stress in LS174T colonic epithelial cells. BMC Complementary and Alternative Medicine. Under revision, 2016

Lee, D.M., Battson, M.L., Jarrell, D., Cox-York, K., Foster, M.T., Weir, T.L., Gentile, C.L., 2016. Fuzhuan tea reverses arterial stiffening following modest weight gain in mice. Nutrition. Dx.doi.org/10.1016/j.nut.2016.07.010

Lemas, D.J., Young, B.E., Baker, P.R., Tomczik, A., Soderborg, T.K., Hernandez, T.L., de la Houssaye, B.A., Robertson, C.E., Rudolph, M.C., Ir, D., Patinkin, Z.W., Krebs, N.F., Santorico, S.A., Weir, T.L., Barbour, L.A., Frank, D.N., Friedman, J.E., 2016. Alterations in human milk leptin and insulin impact early changes in the infant gut microbiome. American Journal Clinical Nutrition. 103, 1291.

Liang, X., Yang, Q., Fu, X., Rogers, C.J., Wang, B., Pan, H., Zhu, M.J., Nathanielsz, P.W., and Du, M., 2016. Maternal obesity epigenetically alters visceral fat progenitor cell properties in male offspring mice. Journal of Physiology, 594: 4453-666

Liu, Y., Hilakivi-Clarke, L., Zhang, Y., Wang, X., Pan, YX., Xuan, J., Fleck, S.C., Doerge, D.R., Helferich, W.G., 2015. Isoflavones in soy flour diet have different effects on whole-genome expression patterns than purified isoflavone mix in human MCF-7 breast tumors in ovariectomized athymic nude mice. Mol Nutr Food Res. Mar 27. doi: 10.1002/mnfr.201500028. [Epub ahead of print] PMID:25820259.

Luo, T., Snyder, S.M., Zhao, B., Sullivan, D.K., Hamilton-Reeves, J., Guthrie, G., Ricketts, M.L., Shiverick, K.T., Shay, N., 2016. Gene expression patterns are altered in athymic mice and metabolic syndrome factors are reduced in c57bl/6j mice fed high-fat diets supplemented with soy isoflavones. J Agric Food Chem. 64, 7492-7501. PMID: 27653593

Madak, Erdogan Z, Gong, P, Zhao, YC, Xu, L, Wrobel, KU, Hartman, JA, Wang, M, Cam, A, Iwaniec, UT, Turner, RT, Twaddle, NC, Doerge, DR, Khan, IA, Katzenellenbogen, JA, Katzenellenbogen, BS, and Helferich, WG., 2015. Dietary licorice root supplementation improves diet-induced weight gain, lipid deposition and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland. Mol Nutr Food Res. Nov 10. doi: 10.1002/mnfr.201500445. [Epub ahead of print]. PMID:26555669

Madeen, E.P., Löhr, C.V., You, H., Siddens, L.K., Krueger, S.K., Dashwood, R.H., Gonzalez, F.J., Baird, W.M., Ho, E., Bramer, L., Waters, K.M. and Williams, D.E., 2016. Dibenzo[def,p]chrysene transplacental exposure in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice. Molec. Carcinogenesis, March 17, DOI 10.1002/mc.22480 [Epub ahead of print].

Madeen, E.P., Ognibene, T.J., Corley, R.A., McQuistan, T.J., Baird, W.M., Bench, G., Turteltaub, K.W. and Williams, D.E., 2016. Human micro-dosing with carcinogenic polycyclic aromatic hydrocarbons: In vivo pharmacokinetics of dibenzo[def,p]chrysene and metabolites by UPLC accelerator mass spectrometry. Chem. Res. Toxicol., in press.

Madeen, E.P. and Williams, D.E. 2016. Environmental PAH exposure and male idiopathic infertility: A review on early life exposures and adult diagnosis. Rev. Environ. Hlth., in press.

Mahalingam, S, Gao, L, Gonnering, M, Helferich, WG, Flaws, JA., 2016. Equol inhibits growth, induces atresia, and inhibits steroidogenesis of mouse antral follicles in vitro. Toxicol Appl Pharmacol. 295, 47-55. doi: 10.1016/j.taap.2016.02.009. [Epub ahead of print] PMID:26876617

Male, D., Wu, W., Mitchell, N.J., Bursian, S., Pestka, J.J., Wu, F., 2016. Modeling the emetic potencies of food-borne trichothecenes by benchmark dose methodology. Food Chem Toxicol 94, 178-185.

Mexia, N., Gaitanis, G., Velegraki, A., Soshilov, A., Denison, M.S. and Magiatis, P., 2015. Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast, Arch. Biochem. Biophys. 571, 16-20. PMC4454357

Mohammad, RM, Muqbil, I, Lowe, L, Yedjou, C, Hsu, HY, Lin, LT, Siegelin, MD, Fimognari, C, Kumar, NB, Dou, QP, Yang, H, Samadi, AK, Russo, GL, Spagnuolo, C, Ray, SK, Chakrabarty, M, Morre, JD, Coley, HM, Honoki, K, Fujii, H, Georgakilas, AG, Amedei, A, Niccolai, E, Amin, A, Ashraf, SS, Helferich, WG, Yang, X, Boosani, CS., Guha, G, Bhakta, D, Ciriolo, MR, Aquilano, K, Chen, S, Mohammed, SI, Keith, WN, Bilsland, A, Halicka, D, Nowsheen, S, Azmi, AS., 2015. Broad targeting of resistance to apoptosis in cancer. 2015 Semin Cancer Biol. Apr 28. pii: S1044-579X(15)00016-4. DOI: 10.1016/j.semcancer.2015.03.001. [Epub ahead of print]. PMID: 25936818

Monsanto, S.P., Hintze, K.J., Ward, R.E., Larson, D.P., Lefevre, M., Benninghoff, A., 2016. The new total Western diet for rodents does not induce an overweight phenotype or alter parameters of metabolic syndrome in mice. Nutrition Research, 36, 1031-1044. dx.doi.org/10.1016/j.nutres.2016.06.002

Monson, M.S., Cardona, C.J., Coulombe, R.A., and Reed, K.M., 2016. Hepatic transcriptome responses of domesticated wild turkey embryos to Aflatoxin B1. Toxins 8 (1). doi: 10.3390/toxins8010016

Monson, M. S., Coulombe, R.A., and Reed, K.M., 2016. Sensitivity and response of poultry to aflatoxin B1 exposure. Agriculture doi:10.3390/agriculture50x000x.

Monson, M. S., Settlage, R.E., Mendoza, K.M., Rawal, S., El-Nezami, H., Coulombe, R.A., and K.M. Reed, K.M., 2015. Modulation of the spleen transcriptome in domestic turkey (Meleagris gallopavo) in response to aflatoxin B1 and probiotics. Immunogenetics DOI 10.1007/s00251-014-0825-y

Nerurkar, P.V., Hwang, P.W., Saksa, E., 2015. Anti-diabetic potential of noni: The yin and the yang. Molecules. 20, 17684-719. doi: 10.3390/molecules201017684.

Patel, S, Peretz, J, Pan, YX, Helferich, WG, Flaws, JA., 2016. Genistein exposure inhibits growth and alters steroidogenesis in adult mouse antral follicles. Toxicol Appl Pharmacol. 293, 53-62. doi: 10.1016/j.taap.2015.12.026. Epub 2016 Jan 12. PMID:26792615

Rada, X., Todd, J., Friedman, M., Patel, J., Jaroni, D., and Ravishankar, S., 2016. Combining essential oils and olive extract for control of multi-drug resistant Salmonella enterica on organic leafy greens. SDRP Journal of Food Science & Technology 1, 1-9.

Rendeiro, C, Sheriff, A, Bhattacharya, TK, Gogola, JV, Baxter, JH, Chen, H, Helferich, WG, Roy, EJ, Rhodes, JS., 2016. Long-lasting impairments in adult neurogenesis, spatial learning and memory from a standard chemotherapy regimen used to treat breast cancer. Behav Brain Res. 315, 10-22. doi: 10.1016/j.bbr.2016.07.043. [Epub ahead of print] PMID:27478140

Rensvold, J.W., Krautkramer, K.A., Dowell, J.A., Denu, J.M., and Pagliarini, D.J., 2016. Iron deprivation induces transcriptional regulation of mitochondrial biogenesis. Journal of Biological Chemistry, 291, 20827-20837

Romagnolo, D.F., Jackson, K.A., Sparks, P.L., Selmin, O.I. 2016. Building the Mediterranean Pyramid-PART B:  Balancing the plate. In: Mediterranean Diet: Dietary Guidelines and Impact on Health and Disease. Humana Press/Springer, Eds. Romagnolo, Selmin. Chapter 20, pg. 275-288.

Romagnolo, D.F., Papoutsis, A.J., Laukaitis, C., Selmin, O.I. 2015. Constitutive expression of AhR and BRCA-1 promoter CpG hypermethylation as biomarkers of ERα-negative breast tumorigenesis. BMC Cancer. 15, 1026.

Romagnolo, D.F., Selmin, O.I. Co-Editors. 2016. Mediterranean Diet: Dietary Guidelines and Impact on Health and Disease. Humana Press/Springer.

Romagnolo, D.F., Selmin, O.I. 2015. Epigenetics of Endocrine Tumors in Women and Dietary Prevention. In: Preventive Nutrition, Fifth Edition, Humana Press/Springer, Eds. Bendich, Deckelbaum, Chapter 9, pg. 153-166.

Romagnolo, D.F., Selmin, O.I. 2016. Mediterranean diet and lifestyle in a modern world context In: Mediterranean Diet: Dietary Guidelines and Impact on Health and Disease. Humana Press/Springer, Eds. Romagnolo, Selmin. Chapter 2, pg. 15-26.

Schreurs, A-S., Shirazi-Fard, Y., Shahnazari, M., Alwood, J.S., Truong, T.A., Tahimic, C.G.T., Limoli, C.L., Turner, N.D., Halloran, B., and Globus, R.K., 2016. Dried plum diet protects from bone loss caused by ionizing radiation. Scientific Reports DOI: 10.1038/srep21343. PMID 26867002.

Selmin, O.I., Daniels, K.D., Grunwald, J.T., Ramos, S.A., Propper, C.R., Romagnolo, D.F. 2016. Epigenetics of breast cancer: modifying role of environmental and bioactive food compounds. Mol Nutr Food Res. 60, 1310-29.

Selmin, O.I., Fang, C., Lyon, A.M., Doetschman, T.C., Thompson, P.A., Martinez, J.D., Smith, J.W., Lance, P.M., Romagnolo, D.F. 2016. Inactivation of adenomatous polyposis coli reduces bile acid/farnesoid X receptor expression through Fxr gene CpG methylation in mouse colon tumors and human colon cancer cells. J Nutr. 146, 236-4.

Selmin, O.I., Romagnolo, A.P.G., Romagnolo, D.F. 2016. The Mediterranean diet and neurodegenerative diseases. In: Mediterranean Diet: Dietary Guidelines and Impact on Health and Disease. Humana Press/Springer, Eds. Romagnolo, Selmin. Chapter 12, pg. 153-164.

Selmin, O.I., Romagnolo, D.F. 2016. Building the Mediterranean Pyramid-PART A: Mediterranean recipes. In: Mediterranean Diet: Dietary Guidelines and Impact on Health and Disease. Humana Press/Springer, Eds. Romagnolo, Selmin. Chapter 19, pg. 261-273.

Sheflin, A.M., Borresen, E.C., Kirkwood, J., Boot, C., Whitney, A.K., Lu, S., Brown, R.J., Broeckling, C.D., Ryan, E.P., Weir, T.L., 2016. Dietary supplementation with rice bran or navy bean alters gut bacterial metabolism in colorectal cancer survivors. Molecular Nutrition and Food Research. 10.1002/mnfr.201500905.

Sheng, L., Rasco, B., and Zhu, M.J., 2016. Cinnamon oil inhibited Shiga toxin 2 phage induction and Shiga toxin 2 production in E. coli O157:H7. Applied Environmental Microbiology, 82, in press.

Sheng, L., Olsen, S.A., Hu, J., Yue, W., Means, W.J., and Zhu, M.J., 2016. Grape seed extract regulates virulence factors of CDC “top-six” non-O157 STEC through inhibiting quorum sensing. International Journal of Food Microbiology, 229: 24-32.

Strakovsky, RS, Lezmi, S, Shkoda, I, Flaws, JA, Helferich, WG, Pan, YX., 2015. In utero growth restriction and catch-up adipogenesis after developmental di (2-ethylhexyl) phthalate exposure cause glucose intolerance in adult male rats following a high-fat dietary challenge. J Nutr Biochem. Jun 20. pii: S0955-2863(15)00145-X. doi: 10.1016/j.jnutbio.2015.05.012. [Epub ahead of print]. PMID:26188368

Strakovsky, RS, Wang, H, Engeseth, NJ, Flaws, JA, Helferich, WG, Pan, YX, Lezmi, S., 2015. Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis. Toxicol Appl Pharmacol. 284, 101-12. PMID: 25748669

Tang, S., Avena-Bustillos, R.J., Lear, M., Sedej, I., Holstege, D.M., Friedman, M., McHugh, T.H., Wang, S.C., 2016. Evaluation of thermal processing variables for reducing acrylamide in canned black ripe olives. J. Food Eng. 191, 124-130.

Teeguarden, J.G., Tan, Y.-M., Edwards, S.W., Leonard, J.A., Anderson, K.A., Corley, R.A., Harding, A.K., Kile, M.L., Simonich, S.M., Stone, D., Tanguay, R.L., Waters, K.M., Harper, S.L. and Williams, D.E., 2016. Completing the link between exposure science and toxicology for improved environmental health decision making: The aggregate exposure pathway framework. Environ. Sci. Technol., Feb. 10, Epub ahead of print, PMID: 26759916. *Featured manuscript of this ES&T issue.

Vasta, J.D., Andersen, K.A., Deck, K.M., Nizzi, C.P., Eisenstein, R.S. and Raines, R.T., 2016. Selective inhibition of collagen prolyl-4-hydroxylase in human cells. ACS Chemical Biology 11:193-9

Vinay, DS, Ryan, EP, Pawelec, G, Talib, WH, Stagg, J, Elkord, E, Lichtor, T, Decker, WK, Whelan, RL, Hmc, SK, Signori, E, Honoki, K, Georgakilas, AG, Amin, A, Helferich, WG, Boosani, CS, Guha, G, Ciriolo, MR, Chen, S, Mohammed, SI, Azmi, AS, Keith, WN, Bhakta, D, Halicka, D, Fujii, H, Aquilano, K, Ashraf, SS, Nowsheen, S, Yang, X, Choi, BK, Kwon, BS., 2015. Immune evasion in cancer: Mechanistic basis and therapeutic strategies. Seminars in Cancer Biology Mar 24. pii: S1044-579X(15)00019-X. doi: 10.1016/j.semcancer.2015.03.004. [Epub ahead of print] PMID: 25818339

Wang, B., Yang, Q., Harris, C.L., Nelson, M.L., Busboom, J.R., Zhu, M.J., and Du, M., 2016. Nutrigenomic regulation of adipose tissue development – role of retinoic acid. Meat Science, 120: 100-106.

Wang, R., Kang, Y., Löhr, C.V., Fischer, K.A., Bradford, S.S., Johnson, G., Dashwood, W.-M., Williams, D.E., Ho, E. and Dashwood, R.H., 2016. Reciprocal regulation of BMF and BIRC5 (survivin) linked to Eomes overexpression in colorectal cancer. Cancer Lett. 381, 341-348. PMID:27539959

Wang, W, Belosay, A, Yang, X, Hartman, JA, Song, H, Iwaniec, UT, Turner, RT, Churchwell, MI, Doerge, DR, and Helferich, WG., 2016. Effects of letrozole on breast cancer micro-metastatic tumor growth in bone and lung in mice inoculated with murine 4T1 cells. Clin Exper Metas, 33, 475-85. doi: 10.1007/s10585-016-9792-z. Epub 2016 May 21. PMID:27209469

Wang, Z, Dabrosin, C, Yin, X, Fuster, MM, Arreola, A, Rathmell, WK, Generali, D, Nagaraju, GP, El-Rayes, B, Ribatti, D, Chen, YC, Honoki, K, Fujii, H, Georgakilas, AG, Nowsheen, S, Amedei, A, Niccolai, E, Amin, A, Ashraf, SS, Helferich, B, Yang, X, Guhas, G, Bhaktas, D, Ciriolot, MR, Aquilanot, K, Chen, S, Halicka, D, Mohammed, SI, Azmi, AS, Bilsland, A, Keith, WN, Jensen, LD., 2015. Broad targeting of angiogenesis for cancer prevention and therapy. Semin Cancer Biol. Jan 16. pii:S1044-579X(15)00002-4. doi: 10.1016/j.semcancer.2015.01.001. [Epub ahead of print] Review. PMID: 25600295

Ward, R.E., Benninghoff, A., Healy, B.J., Li, M., Vagu, B., Hintze, K.J., Consumption of the total Western diet differentially affects the response to green tea in rodent models of chronic disease compared to the AIN93G diet. Molecular Nutrition and Food Research, (in press).

Watson, G.W., Wickramasekara, S., Maier, C.S., Williams, D.E., Dashwood, R.H. and Ho, E., 2015. Assessment of global proteome in LNCaP cells by 2D-RP/RP LC-MS/MS following sulforaphane exposure. EuPA Open Proteomics Aug. 15, 2015, DOI 10.1016/j.euprot.2015.08.002.

Watson, G.W., Wickramasekara, S., Fang, Y., Maier, C.S., Williams, D.E., Dashwood, R.H., Perez, V.I. and Ho, E., 2015. HDAC activity is not required for basal autophagic flux in metastatic prostate cancer cells. Exp. Biol. Med., Dec. 6. Pii: 1535370215618518.

Whitney, A.K. and Weir, T.L., 2016. Inhibitory activity of Fuzhuan tea fractions against Salmonella enterica and enteric pathogens. Current Topics in Phytochemistry 13, 17-27.

Whitney, A.K. and Weir, T.L., 2015. Interaction of caffeine with the SOS response pathway in Escherichia coli. Gut Pathogens 7, 21.

Wu, W., Zhou, H.R., Bursian, S.J., Link, J.E., Pestka, J.J., 2016a. Calcium-sensing receptor and transient receptor ankyrin-1 mediate emesis induction by deoxynivalenol (vomitoxin). Toxicol Sci.

Wu, W., Zhou, H.R., Bursian, S.J., Link, J.E., Pestka, J.J., 2016b. Emetic responses to T-2 toxin, HT-2 toxin and emetine correspond to plasma elevations of peptide YY3-36 and 5-hydroxytryptamine. Arch Toxicol 90, 997-1007.

Wu, W., Zhou, H.R., Pestka, J.J., 2016c. Potential roles for calcium-sensing receptor (CaSR) and transient receptor potential ankyrin-1 (TRPA1) in murine anorectic response to deoxynivalenol (vomitoxin). Arch Toxicol.

Xue, Y., Zhang, H., Sun, X., and Zhu, M.J., 2016. Metformin improves ileal epithelial barrier function in interleukin-10 deficient mice. PLoS ONE, accepted.

Yang, G., Bibi, S., Du, M., Suzuki, T., and Zhu, M.J., 2016. Regulation of the intestinal tight junction by natural polyphenols: a mechanistic perspective. Critical Reviews in Food Science and Nutrition, in press.

Yang, Q., Liang, X., Sun, X., Fu, X., Zhang, L., Rogers, C.J., Wang, S., Wang, B., Maricelli, J.W., Viollet, B., Rodger, B.D., Zhu, M.J., and Du, M., 2016. AMPK/α-ketoglutarate axis dynamically mediates DNA demethylation in the Prdm16 promoter and brown adipogenesis. Cell Metabolism, in press.

Yang, X., Belosay A., Hartman, J.A., Song H., Zhang Y., Wang W., Doerge D.R. and Helferich W.G., 2015. Dietary soy isoflavones increase metastasis to lungs in an experimental model of breast cancer with bone micro-tumors. Clin Exp Metastasis. 32, 323-333. PMID: 25749878

Yaswen, P, MacKenzie, KL, Keith, WN, Hentosh, P, Rodier, F, Zhu, J, Firestone, GL, Matheu, A, Carnero, A, Bilsland, A, Sundin, T, Honoki, K, Fujii, H, Georgakilas, AG, Amedei, A, Amin, A, Helferich, B, Boosani, CS, Guha, G, Ciriolo MR, Chen, S, Mohammed, SI, Azmi, AS, Bhakta, D, Halicka, D, Niccolai, E, Aquilano, K, Ashraf, SS, Nowsheen, S, Yang, X., 2015. Therapeutic targeting of replicative immortality. Semin Cancer Biol. Apr 10. pii: S1044-579X(15)00022-X. doi: 10.1016/j.semcancer.2015.03.007. [Epub ahead of print] Review. PMID: 25869441

Yin, Q., Tang, L., Cai, K., Tong, R., Sternberg, R., Yang, X., Dobrucki, L.W., Borst, L.B., Kamstock, D., Song, Z., Helferich, W.G., Cheng, J., Fan, T.M., 2016. Pamidronate functionalized nanoconjugates for targeted therapy of focal skeletal malignant osteolysis. Proc Natl Acad Sci USA. 113, E4601-9. doi: 10.1073/pnas.1603316113. Epub 2016 Jul 25. PMID:27457945

Zhang, H., Du, M., Yang, Q., and Zhu, M.J., 2016. Butyrate suppresses murine mast cell proliferation and cytokine production through inhibiting histone deacetylase. Journal of Nutritional Biochemistry, 27: 299-306.

Zhou, H.R., Pestka, J.J., 2015. Deoxynivalenol (vomitoxin)-induced cholecystokinin and glucagon-like peptide-1 release in the stc-1 enteroendocrine cell model is mediated by calcium-sensing receptor and transient receptor potential ankyrin-1 channel. Toxicol Sci 145, 407-417.

Zhu, H., Du, M., Fox, L., and Zhu, M.J., 2016. Bactericidal effects of Cinnamomum cassia oil against bovine mastitis bacterial pathogens. Food Control, 66: 291-299.