Brief Summary of Minutes of Annual Meeting

Community of Practice (CoP), eXtension: ABC's of n-3 content. To start eXtension webpage, we need 150 FAQs and answers, min of 250 content pages. The initial deadline date was September 30. We have 142 FAQs, very close to 150, and almost 50 content pages, mostly recipes. Right now we need to work on reaching the 250 content page goal. As far as research related to the CoP, Deb has helped lead research including over 310 interviews with college students about what they want to know about omega-3 FAs and 140 interviews with others. Deb is working with students to create a webpage for SNAP-Ed on Second Life, a webpage where you create a virtual you. She is also creating a grocery store tour podcast of omega-3 fatty acids. It has been effective at helping consumers find omega-3 fatty acid foods and can be linked to the eXtension page but not considered a content page. So, we can use Second Life for individuals to create avatars to do a grocery store tour. Deb would like to suggest changes to the eXtension format to make the pages more interactive, etc. There are different types of content pages: recipes (we need to think about if we want to list how much omega-3s are in them or is the fact they include salmon good enough); powerpoints (using slide sorter to choose just one) with narrative; and regular content pages. Administrative Update [David Jackson]. Dr. Jackson printed out the official list of members and wants to make sure that we have an accurate and representative list of members. Members do not need to be University faculty to be members of the team or have PhDs. They can be industry members (like Jerome) and practitioners. We would like to expand the group for the next proposal, especially considering retirements. Both Jennifer and Nancy will be retiring next year, so will not be serving on the CoP. We will invite the CoP members to officially join the multi-state team. Kate also knows of a researcher, Susan Raatz, Grand Forks Human Nutrition Center, who works with commodity groups, commercial sector, who would be a great addition to the group. We need a RD who can interact with ADA, RD. One idea was Gretchen VanEss. We also need to identify which committee/group they want to be involved with. The multi-state research program is valued at $51.6 million dollars, $48 million goes to states, approx. $1 million per state. The state money is to help encourage travel to yearly meetings. The projects are approved every 5 years based on demonstrated collaboration between states on research. This is different from the notion that we are working on a common goal, but everyone has their own research projects. The intention is to share research. The next proposal/plan essentially needs to be completed next year. It should take into consideration how to come together in common research themes. We are in a good place in terms of common goals, but we need to show that researchers are working together. We definitely are doing that but need to document that, as well as the translational approach with bench scientists contributing to the behavioral CoP. Another benefit is a CoP; we need to have that project online and readily accessible BEFORE renewal. The project expires September 30, 2012. Following are the deadlines which can also be found at http://ncra.wisc.edu/approvalprocess.htm : By September 15, 2011, we will need to request/notify them that of a re-write. By October 15th, 2011, we need to post the objectives. By November 15th, 2011, membership lists need to be submitted. December 1st the proposal needs to be completed. Dec. 1 15th, it's reviewed. Late March/Early April final decisions made. By June 1st, all revisions need to be made. Mid-July revisions approved. All projects expire September 30th and begin again October 1st. Everything needs to be completed this time next year. We need to develop goals for the next proposal and start assembling the final report and the next proposal by the EB meeting. Industry/private funds can be accepted by the group. NIFA Update [Susan Welsh]. Susan gave an update on the new structure of NIFA, focus areas, and the childhood obesity research initiatives. Stay tuned for the release of the new Dietary Guidelines for Americans and HP2010 (with addition of solid fats and sugars) in December. It is likely that the pyramid will be revised. CoP, eXtension. We need to identify funds to help Deepika for salary. Martek is one thought. If any funding is provided to the eXtension foundation, the funders could have their logo in the eXtension page depending on their level. We received a tour of the eXtension webpage. Some concerns about the website that Deb is working with eXtension on include: rotating pictures (some may not attract people as much); academic nature of webpage (it's not that consumer-friendly). There is someone from eXtension that finds press releases on related topics that can be featured on the webpage. We need to make sure that we utilize the resources. Please set-up an account at eXtension and for the ABCs of Omega-3s CoP at: http://people.extension.org Evaluation Plan: Qualitative assessment of the webpage and what they enjoy and also what they learned (using moodle). Then wed like to look at health professionals' views. Listserves. Please note there are two different listserves. The NC1039 one is for the multi-state project and ABC is for the whole community of practice. Station Reports. Please send peer-reviewed publications and presentations to Doug Mashek, dmashek@umn.edu, current secretary and incoming Chair, from this past year for our final station report. This is REQUIRED. Again, we will need to document the collaborations. If its not there, it will be difficult to justify approval. Notes to Chair (Doug). The agenda needs to be approved before we receive authorization (see notes about dates and agenda items) in late July/early August. Members cannot receive approval for travel and make travel arrangements until they receive official approval notification (members will receive a NIMMS approval email when this takes place). David Jackson can accept registration too. Draft of Proposal for Reauthorization. We developed committees to work on a draft of the proposal in the next 6 months by EB. " Bench/Clinical: Kimberly, Jay, Kate, Concetta, Mary, Doug, Shane, Susan, Jerome " Community/extension: Deb, Nancy, Jennifer, Elena 2011 meetings: " ADA FNCE 2011 is Sept. 24 - 27 in San Diego " EB 2011 is April 9 - 13, in Washington, DC " Obesity Society Meeting is Sept. 30 - October 5, in Orlando, FL There will be a mid-year meeting at EB. The re-write will be discussed at the meeting. The meeting will be Friday, April 8th, before the meeting starts onsite or at the hotel (where they will have wireless). Next year's meeting will be all-day Oct. 26th and 27th then end at noon on the 28th in Washington, DC. Susan Welsh agreed to host the meeting again. This would allow more work on the CoP. We also need to finalize the draft for project approval. " Oct. 26th - Wednesday - CoP " 27th - Thursday CoP and multi-state (1/2 day) joint meeting, then multi-state Thursday afternoon " Finish up the report and write new proposal " 28th - Friday (1/2 day) multi-state " Note to CoP: You are welcome to stay for the whole meeting " Note to multi-state: You are welcome to come on Wednesday Timeline We will need to do the assessment of the eXtension webpage on the next report. Station Reports - everyone who is conducting research related to omega-3 fatty acids provided updates. -Nancy Lewis discussed the development of a food frequency questionnaire on omega-3 fatty acids with Latinas. Chicken, hard-boiled eggs, and mole were major contributors of omega-3 fatty acids. There was a positive acculturation with omega-3 fatty acids. Education was also a contributor. We discussed creating a sub-scale that would be easy to assess DHA and ALA for individuals who use the eXtension webpage. Jerome discussed some of the initiatives/projects he is working on, as new member and for possible partnership. His focus is on animal science, which represents a new discipline represented in the group. One project he is working on is related to animal feed, particularly for cattle. The omega-3 supplement for livestock would be part of their daily food intake. The omega-3 helps with animal and human health through different food sources (meat, dairy, butter). Based on some of their research, ground beef patties (4 ounce) contain 200mg of omega-3. Hes going to send information on how much DHA, ALA. They are working on a trademark logo for the food type. He wants to work with identifiers in wireless communication. In one county, they have 64,000 head. In the top 4 states, they are producing 78 billion pounds of milk. Elena will look at the use of eXtension by FCS Extension Agents, so that the ABCs for Omega-3s can be used as a training tool as well as consumer tool. Deepika provided an update on their research on what people know and want to know about omega-3 fatty acids with college students and other individuals using a written questionnaire. They plan on submitting the data for publication by next year. Mary is interested in omega-3 fatty acids and reproductive health. There were correlational plasma phospholipids and omega-3 fatty a She is also interested in WIC food package  especially fish in the breastfeeding moms. She found using a semi-quantitative questionnaire that intake was 238 mg per day in WIC population and 311 in private population, big difference was in supplemental intake of n-3s among private population. A potential for joint partnerships is to help recruit WIC subjects with a higher representation from African American/black population. Another study was related to omega-3 oil stability, Crisco Puritan Oil with DHA. They aged it out. They didn't have to use the aging system since the product comes in a plastic bottle. Within one week, they lost almost half of DHA. At 10 weeks of aging, they had 0 DHA left in the product. Where is it going? It's forming lipo-peroxide. Finally, she is interested in looking at alleles in predicting DHA levels. Timeline for Reauthorization. " Sept. 15 - Deadline to submit a request to write a proposal in NIMSS " Oct. 15 - Deadline to upload the objectives section in NIMSS " Dec. 1 - Completed proposal due in NIMSS Sub-groups will need to be formed and start communication ASAP in order to develop objectives by the time of the EB meeting. Mary is going to lead the basic-clinical group. Members include: Doug, Jay, Shane, Raz, Concetta, Kate, Jerome, and Kimberly. The group will need to determine objectives and future goals either via email, conference call, or in-person meeting. Jerome will initiate communication for an animal-human group. Members include: Jerome, Kate, Jay, and maybe Elena (for the school part). The applied-extension sub-group will focus on continued development and evaluation of the eXtension community of practice on omega-3 fatty acids, such as with Extension Educators working with the public. Elena will help work on this with Deb, Audrey, Deepika, Jennifer, and a new person Lisa Fransen (UNL). At EB, we are going to have to get together for at least a few hours to finalize the objectives. Before then, we need to set-up two conference calls to discuss (1st one for bench scientists in Nov., 2nd on Fri., January 22). Appointed incoming secretary Kate Claycombe. Recommendation for next year's meeting: Station reports should be provided at the beginning of the multi-state project meeting to provide ample time to discuss collaborations. Evaluation of eXtension webpage. We can get hits, where they go, what they do, etc. They will be using Second Life and other social media to see if they can figure out how people get to the webpage (facebook, etc.). Content Pages Needed - " Ideas for Novel Food Sources of Omega-3 Fatty Acids " Stability of Omega-3 Fatty Acids " Animal Feed and Omega-3 Fatty Acids " DRIs and Omega-3 Fatty Acids  what is optimum?

Objective 1: To determine the health promotion and disease prevention effects of both the forms and the amounts of n-3 fatty acids by correlation with tissue functions, and with alterations in biomarkers, relevant to optimal health and disease prevention. " The use of rodent models to identify that linolenic acid intake enhances ovulation similar to very high EPA/DHA ingestion in rats. " Development of a new immunohistochemical method to detect how toll-like receptor-2 (TLR-2) and transcription factor nuclear factor-kappa B (NF-kB) mediate inhibitory effects of stearadonic acid and EPA. Development of these particular methods enabled us to determine target proteins and exact intracellular signaling pathways underlying anti-inflammatory effects of n-3 PUFAs in adipose stem cells. " Identification of genes that correlated with dietary effects of PUFA indicating that these genes may be potential biomarkers for dietary fat intake. " Dietary studies in rodents revealed that very long chain omega-3 fatty acids, but not linolenic acid, are responsible for reducing TAG synthesis. Additionally, linolenic acid is readily converted to very long chain omega-3 fatty acids in the liver providing additional insight into the regulation of omega-3 metabolism. " Identification the omega-3 fatty acids can modify lipid raft organization on B-cells. " Data showing that EPA enhance the regression of prostate cancer following hormone ablation therapy and delayed tumor relapse. " Rodent studies revealing that central administration of omega-3 fatty acids suppress food intake and promotes weight loss indicating that omega-3 fatty acids may regulate metabolism, in part, through the central nervous system. " Data showing that dietary EPA feeding prevents and reverses insulin resistance in high-fat diet-induced obese C57BL/6J mice via modulation of adipose tissue inflammation. EPA supplementation of a high fat diet also reduces adipose tissue lipogenesis and fatty acid oxidation. Objective 2: To examine dietary levels of both form and amount of n-3 PUFA that promote health and reduce disease that are relevant and achievable in human diets using the human equivalent dose method (allometric scaling) in rodent models. " We show that mice are more efficient at elongating and desaturating linolenic acid to EPA at doses above 0.9en% as compared to humans, where supplemental doses of linolenic acid at all levels to humans had little impact on plasma and RBC fatty acid composition content. " Human data suggests that modifying dietary levels of linolenic acid has no impact of changing tissue arachidonic acid levels either by reducing these levels by as much as 90% or increasing the levels 6 fold. Objective 3: To develop, test and disseminate effective means for translating research on the health promoting and disease preventing effects of n-3 PUFA into consumer food choices. " Development of Extension omega-3 site entitled A, B, Cs of omega-3s. " Characterization of dietary intakes of omega-3 fatty acids between WIC participants and private obstetrical patients. Findings revealed that those on WIC had lower omega-3 fatty acids intake suggesting an economic disparity exists for omega-3 fatty acid intake. " Identification of foods responsible for omega-3 fatty acids intake in Hispanic women.

Broughton KS, Bayes J, Culver B. High ±-linolenic acid and fish oil ingestion promotes ovulation to the same extent in rats. Nutr Research 2010;30:731-738 Kalupahana NS, Claycombe K, Newman SJ, Stewart T, Siriwardhana N, Matthan N, Lichtenstein AH, Moustaid-Moussa N. Eicosapentaenoic Acid Prevents and Reverses Insulin Resistance in High-Fat Diet-Induced Obese Mice via Modulation of Adipose Tissue Inflammation. J Nutr. 2010;140(11):1915-1922. Rockett BD, Salameh M, Carraway K, Morrison K, Shaikh SR. n-3 PUFA improves fatty acid composition, prevents palmitate-induced apoptosis, and differentially modifies B cell cytokine secretion in vitro and ex vivo. J Lip Res. 2010;51, 1284-1297. Shaikh SR, LoCascio DS, Soni SP, Wassall SR, Stillwell W. Oleic- and docosahexaenoic acid-containing phosphatidylethanolamines differentially phase separate from sphingomyelin Biochemica et Biophyscia Acta  Biomembranes. 2009;1788, 2421-2426. Lora KR, Lewis NM, Eskridge KM, Stanek-Krogstrand K, Ritter-Gooder P. Validity and reliability of an omega-3 fatty acid food frequency questionnaire for first-generation Midwestern Latinas. Nutr Research 2010;30:550-557. Whelan J, Jahns L, Kavanagh-Prochaska K. DHA: Measurements in Food and Dietary Exposure. Prostaglandins Leukot Essent Fatty Acids. 2009;81:133-136.