NRSP7: A National Agricultural Program for Minor Use Animal Drugs

(National Research Support Project Summary)

Status: Inactive/Terminating

SAES-422 Reports

12/22/2009

06/28/2010

06/29/2010

11/10/2010

07/12/2011

Presentations


Groocock, Geoffrey H., Emily R. Cornwell, Rodman G. Getchell, Gregory A. Wooster, Paul R. Bowser. 2010. Efficacy of iodophore disinfection of viral hemorrhagic septicemia virus (VHSV) on walleye (Sander vitreus) eggs. Annual Meeting of the New York Chapter of the American Fisheries Society. Lake George, New York. 10-12 February 2010.

Groocock, G.H., E.R. Cornwell, R.G. Getchell, G.A. Wooster, and P.R. Bowser. 2010. Iodophor Disinfection of Walleye (Sander vitreus) Eggs. 35th Eastern Fish Health Workshop. Shepherdstown, WV. 24-28 May 2010.

Publications


Clothier, K. A., Leavens, T., Griffith, R. W., Wetzlich, S. E., Baynes, R. E., Riviere, J. E., and Tell, L. A. (2011) Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus), J Vet Pharmacol Ther. doi: 10.1111/j.1365-2885.2011.01300.x

Clothier, K. A., Leavens, T., Griffith, R. W., Wetzlich, S. E., Baynes, R. E., Riviere, J. E., and Tell, L. A. (2011) Pharmacokinetics of tulathromycin after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus), J Vet Pharmacol Ther 34, 448-454.

Emily R. Cornwell, Geoffrey H. Groocock, Rodman G. Getchell, and Paul R. Bowser. 2010. Residual tannic acid destroys virucidal properties of iodine. North American Journal of Aquaculture 73(1):8-12.

Leavens, T. L., Tell, L. A., Clothier, K. A., Griffith, R. W., Baynes, R. E., and Riviere, J. E. (2011) Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats, J Vet Pharmacol Ther. doi: 10.1111/j.1365-2885.2011.01304.x.

Tell, L. A., Brooks, J. W., Lintner, V., Matthews, T., and Kariyawasam, S. (2011) Antimicrobial susceptibility of Arcanobacterium pyogenes isolated from the lungs of white-tailed deer (Odocoileus virginianus) with pneumonia, J Vet Diagn Invest 23, 1009-1013.

12/21/2011

Presentations


Emily R. Cornwell, Geoffrey H. Groocock, Rodman G. Getchell, and Paul R. Bowser. 2010. Residual tannic acid destroys virucidal properties of iodine. North American Journal of Aquaculture 73(1):8-12.

Grismer B, Rowe JD, Carlson J, Wetzlich S, Kieu H, Tell L. Pharmacokinetics of a single subcutaneous injection of tulathromycin in lactating dairy goats (Capra hircus). UC Davis STAR student presentation, September 24, 2011

Rivera S, Tell L. Pharmacokinetics of ceftiofur crystalline free acid in sheep following subcutaneous single-dose administration. Proceedings of the 33rd Annual House Officer Seminar Day, VMTH, University of California Davis, Large Animal/Avian-Exotics/Lab Animal/Primate Presentations, March 11, 2011.

Publications


Doré E, Angelos JA, Rowe JD, Carlson JL, Wetzlich SE, Kieu HT, Tell LA. Pharmacokinetics of ceftiofur crystalline free acid after single subcutaneous administration in lactating and nonlactating domestic goats (Capra aegagrus hircus). J Vet Pharmacol Ther, 34(1):25-30, 2011.

Leavens TL, Tell LA, Clothier KA, Griffith RW, Baynes RE, Riviere JE. Development of physiologically based pharmacokinetic (PBPK) model to predict tulathromycin distribution in goats. The Toxicologist, 50th Annual Meeting of the Society of Toxicology Annual Meeting, Washington DC, Vol 120(2), March 2011.

Romanet J, Smith GW, Leavens TL, Baynes RE, Wetzlich SE, Riviere JE, Tell, LA. Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats. In preparation. Planned submission to AJVR, 2011.

Tell LA, Brooks JW, Lintner V, Matthews T, Kariyawasam S. Antimicrobial susceptibility of Arcanobacterium pyogenes isolated from the lungs of white-tailed deer (Odocoileus virginianus) with pneumonia. J Vet Diagn Invest, 23(5):1009-1013, 2011.

Topic Popovic, N., T. Howell, J.G. Babish and P.R. Bowser. 2011. Cross-sectional study of hepatic CYP1A and CYP3A enzymes in sunshine bass, channel catfish and Nile tilapia following oxytetracycline treatment. Research in Veterinary Science. In press.

Young G, Smith GW, Leavens TL, Wetzlich SE, Baynes RE, Mason SE, Riviere JE, Tell LA. Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats. Res Vet Sci, 90(3):477-479, 2011.

06/15/2012

PRESENTATIONS
Breyer, K.E., R.G. Getchell, G.H. Groocock, L.L. Coffee, G.A. Wooster, P.R. Bowser, H..G. Ketola. 2012. Garlic (Allicin): More Than Just Flavor For Your Fish! 37th Annual Eastern Fish Health Workshop. Lake Placid, New York. 23-27 April 2012.

PUBLICATIONS
Clothier, K. A., Leavens, T., Griffith, R. W., Wetzlich, S. E., Baynes, R. E., Riviere, J. E., and Tell, L. A. (2012) Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus), J Vet Pharmacol Ther 35, 113-120.

Dechant, J. E., Rowe, J. D., Byrne, B. A., Wetzlich, S. E., Kieu, H. T., and Tell, L. A. (2012) Pharmacokinetics of ceftiofur crystalline free acid after single and multiple subcutaneous administrations in healthy alpacas (Vicugna pacos), J Vet Pharmacol Ther. (In Press)

Groocock, G.H., Getchell, R.G., Cornwell, E.R. Frattini, S.A., Wooster, G.A. and Bowser, P.R. (2012) Iodophor Disinfection of Walleye Eggs Exposed to Viral Hemorrhagic Septicemia Virus type IVb. North American Journal of Aquaculture. (In Press)

Leavens, T. L., Tell, L. A., Clothier, K. A., Griffith, R. W., Baynes, R. E., and Riviere, J. E. (2012) Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats, J Vet Pharmacol Ther 35, 121-131.

Topic Popovic, N., T. Howell, J.G. Babish and P.R. Bowser. 2012. Cross-sectional study of hepatic CYP1A and CYP3A enzymes in sunshine bass, channel catfish and Nile tilapia following oxytetracycline treatment. Research in Veterinary Science 93:283-291

01/26/2013

Publications for Project Period 10/09 to 11/12
1. Topic Popovic, N., Howell, T., Babish, J. G., and Bowser, P. R. (2012) Cross-sectional study of hepatic CYP1A and CYP3A enzymes in hybrid striped bass, channel catfish and Nile tilapia following oxytetracycline treatment, Res Vet Sci 92, 283-291.

2. Tell, L. A., Stephens, K., Teague, S. V., Pinkerton, K. E., and Raabe, O. G. (2012) Study of nebulization delivery of aerosolized fluorescent microspheres to the avian respiratory tract, Avian Dis 56, 381-386.

3. Romanet, J., Smith, G. W., Leavens, T. L., Baynes, R. E., Wetzlich, S. E., Riviere, J. E., and Tell, L. A. (2012) Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats, Am J Vet Res 73, 1634-1640.

4. Mehl, M. L., Tell, L., Kyles, A. E., Chen, Y. J., Craigmill, A., and Gregory, C. R. (2012) Pharmacokinetics and pharmacodynamics of A77 1726 and leflunomide in domestic cats, J Vet Pharmacol Ther 35, 139-146.

5. Lee, K. A., Tell, L. A., and Mohr, F. C. (2012) Inflammatory markers following acute fuel oil exposure or bacterial lipopolysaccharide in mallard ducks (Anas platyrhynchos), Avian Dis 56, 704-710.

6. Leclere, M., Magdesian, K. G., Cole, C. A., Szabo, N. J., Ruby, R. E., Rhodes, D. M., Edman, J., Vale, A., Wilson, W. D., and Tell, L. A. (2012) Pharmacokinetics and preliminary safety evaluation of azithromycin in adult horses, J Vet Pharmacol Ther 35, 541-549.

7. Leavens, T. L., Tell, L. A., Clothier, K. A., Griffith, R. W., Baynes, R. E., and Riviere, J. E. (2012) Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats, J Vet Pharmacol Ther 35, 121-131.

8. Hope, K. L., Tell, L. A., Byrne, B. A., Murray, S., Wetzlich, S. E., Ware, L. H., Lynch, W., Padilla, L. R., and Boedeker, N. C. (2012) Pharmacokinetics of a single intramuscular injection of ceftiofur crystalline-free acid in American black ducks (Anas rubripes), Am J Vet Res 73, 620-627.

9. Dechant, J. E., Rowe, J. D., Byrne, B. A., Wetzlich, S. E., Kieu, H. T., and Tell, L. A. (2012) Pharmacokinetics of ceftiofur crystalline free acid after single and multiple subcutaneous administrations in healthy alpacas (Vicugna pacos), J Vet Pharmacol Ther.

10. Cornwell, E. R., Anderson, G. B., Wooster, G. A., Getchell, R. G., Groocock, G. H., Casey, J. W., Bain, M. B., and Bowser, P. R. (2012) Low prevalence of Cyprinid Herpesvirus 3 Found in common carp (Cyprinus carpio carpio) collected from nine locations in the Great Lakes, J Wildl Dis 48, 1092-1096.

11. Clothier, K. A., Leavens, T., Griffith, R. W., Wetzlich, S. E., Baynes, R. E., Riviere, J. E., and Tell, L. A. (2012) Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus), J Vet Pharmacol Ther 35, 113-120.

12. Bowser, P. R., Casey, J. W., Casey, R. N., Quackenbush, S. L., Lofton, L., Coll, J. A., and Cipriano, R. C. (2012) Swimbladder Leiomyosarcoma in Atlantic salmon (Salmo salar) in North America, J Wildl Dis 48, 795-798.

13. Young, G., Smith, G. W., Leavens, T. L., Wetzlich, S. E., Baynes, R. E., Mason, S. E., Riviere, J. E., and Tell, L. A. (2011) Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats, Res Vet Sci 90, 477-479.

14. White, S. D., Bourdeau, P., Bruet, V., Kass, P. H., Tell, L., and Hawkins, M. G. (2011) Reptiles with dermatological lesions: a retrospective study of 301 cases at two university veterinary teaching hospitals (1992-2008), Veterinary dermatology 22, 150-161.

15. Tell, L. A., Brooks, J. W., Lintner, V., Matthews, T., and Kariyawasam, S. (2011) Antimicrobial susceptibility of Arcanobacterium pyogenes isolated from the lungs of white-tailed deer (Odocoileus virginianus) with pneumonia, J Vet Diagn Invest 23, 1009-1013.

16. Strunk, A., Imai, D. M., Osofsky, A., and Tell, L. A. (2011) Dysgerminoma in an eastern rosella (Platycercus eximius eximius), Avian Dis 55, 133-138.

17. Leavens, T. L., Tell, L. A., Clothier, K. A., Griffith, R. W., Baynes, R. E., and Riviere, J. E. (2011) Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats, J Vet Pharmacol Ther.

18. Kline, Y., Clemons, K. V., Woods, L., Stevens, D. A., and Tell, L. A. (2011) Pharmacokinetics of voriconazole in adult mallard ducks (Anas platyrhynchos), Medical mycology 49, 500-512.

19. Hawkins, M. G., Taylor, I. T., Byrne, B. A., Armstrong, R. D., and Tell, L. A. (2011) Pharmacokinetic-pharmacodynamic integration of orbifloxacin in Japanese quail (Coturnix japonica) following oral and intravenous administration, J Vet Pharmacol Ther 34, 350-358.

20. Goetting, V., Lee, K. A., and Tell, L. A. (2011) Pharmacokinetics of veterinary drugs in laying hens and residues in eggs: a review of the literature, J Vet Pharmacol Ther 34, 521-556.

21. Dore, E., Angelos, J. A., Rowe, J. D., Carlson, J. L., Wetzlich, S. E., Kieu, H. T., and Tell, L. A. (2011) Pharmacokinetics of ceftiofur crystalline free acid after single subcutaneous administration in lactating and nonlactating domestic goats (Capra aegagrus hircus), J Vet Pharmacol Ther 34, 25-30.

22. Cornwell, E. R., Eckerlin, G. E., Getchell, R. G., Groocock, G. H., Thompson, T. M., Batts, W. N., Casey, R. N., Kurath, G., Winton, J. R., Bowser, P. R., Bain, M. B., and Casey, J. W. (2011) Detection of viral hemorrhagic septicemia virus by quantitative reverse transcription polymerase chain reaction from two fish species at two sites in Lake Superior, J Aquat Anim Health 23, 207-217.

23. Cornwell, E. R., Cinelli, M. J., McIntosh, D. M., Blank, G. S., Wooster, G. A., Groocock, G. H., Getchell, R. G., and Bowser, P. R. (2011) Epizootic Nocardia infection in cultured weakfish, Cynoscion regalis (Bloch and Schneider), J Fish Dis 34, 567-571.

24. Clothier, K. A., Leavens, T., Griffith, R. W., Wetzlich, S. E., Baynes, R. E., Riviere, J. E., and Tell, L. A. (2011) Pharmacokinetics of tulathromycin after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus), J Vet Pharmacol Ther 34, 448-454.

25. Clothier, K. A., Leavens, T., Griffith, R. W., Wetzlich, S. E., Baynes, R. E., Riviere, J. E., and Tell, L. A. (2011) Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus), J Vet Pharmacol Ther.

26. Young, G., Smith, G. W., Leavens, T. L., Wetzlich, S. E., Baynes, R. E., Mason, S. E., Riviere, J. E., and Tell, L. A. (2010) Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats, Res Vet Sci.

27. Tell, L. A., Clemons, K. V., Kline, Y., Woods, L., Kass, P. H., Martinez, M., and Stevens, D. A. (2010) Efficacy of voriconazole in Japanese quail (Coturnix japonica) experimentally infected with Aspergillus fumigatus, Medical mycology 48, 234-244.

28. Rowe, J. D., Tell, L. A., Carlson, J. L., Griffith, R. W., Lee, K., Kieu, H., Wetzlich, S., and Hallford, D. (2010) Progesterone milk residues in goats treated with CIDR-G((R)) inserts, J Vet Pharmacol Ther 33, 605-609.

29. Hope, K. M., Casey, R. N., Groocock, G. H., Getchell, R. G., Bowser, P. R., and Casey, J. W. (2010) Comparison of quantitative RT-PCR with cell culture to detect viral hemorrhagic septicemia virus (VHSV) IVb infections in the Great Lakes, J Aquat Anim Health 22, 50-61.

30. Clothier, K. A., Jordan, D. M., Loynachan, A. T., and Griffith, R. W. (2010) Safety evaluation of tulathromycin use in the caprine species: tulathromycin toxicity assessment in goats, J Vet Pharmacol Ther 33, 499-502.

31. Bain, M. B., Cornwell, E. R., Hope, K. M., Eckerlin, G. E., Casey, R. N., Groocock, G. H., Getchell, R. G., Bowser, P. R., Winton, J. R., Batts, W. N., Cangelosi, A., and Casey, J. W. (2010) Distribution of an invasive aquatic pathogen (viral hemorrhagic septicemia virus) in the Great Lakes and its relationship to shipping, PLoS One 5, e10156.

32. Spitsbergen, J. M., Blazer, V. S., Bowser, P. R., Cheng, K. C., Cooper, K. R., Cooper, T. K., Frasca, S., Jr., Groman, D. B., Harper, C. M., Law, J. M., Marty, G. D., Smolowitz, R. M., St Leger, J., Wolf, D. C., and Wolf, J. C. (2009) Finfish and aquatic invertebrate pathology resources for now and the future, Comp Biochem Physiol C Toxicol Pharmacol 149, 249-257.

33. Rowe, J. D., Tell, L. A., and Wagner, D. C. (2009) Animal safety report on intravaginal progesterone controlled internal drug releasing devices in sheep and goats, J Vet Pharmacol Ther 32, 303-305.

34. Nguyen, K. Q., Hawkins, M. G., Taylor, I. T., Wiebe, V. J., and Tell, L. A. (2009) Stability and uniformity of extemporaneous preparations of voriconazole in two liquid suspension vehicles at two storage temperatures, Am J Vet Res 70, 908-914.

35. Kosoff, R. E., Chen, C. Y., Wooster, G. A., Getchell, R. G., Bowser, P. R., Clifford, A., Craig, J. L., Lim, P., Wetzlich, S. E., Craigmill, A. L., and Tell, L. A. (2009) Florfenicol residues in three species of fish after 10-day oral dosing in feed, J Aquat Anim Health 21, 8-13.

36. Davis, J. L., Smith, G. W., Baynes, R. E., Tell, L. A., Webb, A. I., and Riviere, J. E. (2009) Update on drugs prohibited from extralabel use in food animals, J Am Vet Med Assoc 235, 528-534.

37. Bowser, P. R., Kosoff, R. E., Chen, C. Y., Wooster, G. A., Getchell, R. G., Craig, J. L., Lim, P., Wetzlich, S. E., Craigmill, A. L., and Tell, L. A. (2009) Florfenicol residues in Nile tilapia after 10-d oral dosing in feed: effect of fish size, J Aquat Anim Health 21, 14-17.

38. Smith, G. W., Davis, J. L., Tell, L. A., Webb, A. I., and Riviere, J. E. (2008) Extralabel use of nonsteroidal anti-inflammatory drugs in cattle, J Am Vet Med Assoc 232, 697-701.

06/30/2001

1. Topic Popovic, N., Howell, T., Babish, J. G., and Bowser, P. R. (2012) Cross-sectional study of hepatic CYP1A and CYP3A enzymes in hybrid striped bass, channel catfish and Nile tilapia following oxytetracycline treatment, Res Vet Sci 92, 283-291.

2. Tell, L. A., Stephens, K., Teague, S. V., Pinkerton, K. E., and Raabe, O. G. (2012) Study of nebulization delivery of aerosolized fluorescent microspheres to the avian respiratory tract, Avian Dis 56, 381-386.

3. Romanet, J., Smith, G. W., Leavens, T. L., Baynes, R. E., Wetzlich, S. E., Riviere, J. E., and Tell, L. A. (2012) Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats, Am J Vet Res 73, 1634-1640.

4. Mehl, M. L., Tell, L., Kyles, A. E., Chen, Y. J., Craigmill, A., and Gregory, C. R. (2012) Pharmacokinetics and pharmacodynamics of A77 1726 and leflunomide in domestic cats, J Vet Pharmacol Ther 35, 139-146.

5. Lee, K. A., Tell, L. A., and Mohr, F. C. (2012) Inflammatory markers following acute fuel oil exposure or bacterial lipopolysaccharide in mallard ducks (Anas platyrhynchos), Avian Dis 56, 704-710.

6. Leclere, M., Magdesian, K. G., Cole, C. A., Szabo, N. J., Ruby, R. E., Rhodes, D. M., Edman, J., Vale, A., Wilson, W. D., and Tell, L. A. (2012) Pharmacokinetics and preliminary safety evaluation of azithromycin in adult horses, J Vet Pharmacol Ther 35, 541-549.

7. Leavens, T. L., Tell, L. A., Clothier, K. A., Griffith, R. W., Baynes, R. E., and Riviere, J. E. (2012) Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats, J Vet Pharmacol Ther 35, 121-131.

8. Hope, K. L., Tell, L. A., Byrne, B. A., Murray, S., Wetzlich, S. E., Ware, L. H., Lynch, W., Padilla, L. R., and Boedeker, N. C. (2012) Pharmacokinetics of a single intramuscular injection of ceftiofur crystalline-free acid in American black ducks (Anas rubripes), Am J Vet Res 73, 620-627.

9. Dechant, J. E., Rowe, J. D., Byrne, B. A., Wetzlich, S. E., Kieu, H. T., and Tell, L. A. (2012) Pharmacokinetics of ceftiofur crystalline free acid after single and multiple subcutaneous administrations in healthy alpacas (Vicugna pacos), J Vet Pharmacol Ther.

10. Cornwell, E. R., Anderson, G. B., Wooster, G. A., Getchell, R. G., Groocock, G. H., Casey, J. W., Bain, M. B., and Bowser, P. R. (2012) Low prevalence of Cyprinid Herpesvirus 3 Found in common carp (Cyprinus carpio carpio) collected from nine locations in the Great Lakes, J Wildl Dis 48, 1092-1096.

11. Clothier, K. A., Leavens, T., Griffith, R. W., Wetzlich, S. E., Baynes, R. E., Riviere, J. E., and Tell, L. A. (2012) Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus), J Vet Pharmacol Ther 35, 113-120.

12. Bowser, P. R., Casey, J. W., Casey, R. N., Quackenbush, S. L., Lofton, L., Coll, J. A., and Cipriano, R. C. (2012) Swimbladder Leiomyosarcoma in Atlantic salmon (Salmo salar) in North America, J Wildl Dis 48, 795-798.

13. Young, G., Smith, G. W., Leavens, T. L., Wetzlich, S. E., Baynes, R. E., Mason, S. E., Riviere, J. E., and Tell, L. A. (2011) Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats, Res Vet Sci 90, 477-479.

14. White, S. D., Bourdeau, P., Bruet, V., Kass, P. H., Tell, L., and Hawkins, M. G. (2011) Reptiles with dermatological lesions: a retrospective study of 301 cases at two university veterinary teaching hospitals (1992-2008), Veterinary dermatology 22, 150-161.

15. Tell, L. A., Brooks, J. W., Lintner, V., Matthews, T., and Kariyawasam, S. (2011) Antimicrobial susceptibility of Arcanobacterium pyogenes isolated from the lungs of white-tailed deer (Odocoileus virginianus) with pneumonia, J Vet Diagn Invest 23, 1009-1013.

16. Strunk, A., Imai, D. M., Osofsky, A., and Tell, L. A. (2011) Dysgerminoma in an eastern rosella (Platycercus eximius eximius), Avian Dis 55, 133-138.

17. Leavens, T. L., Tell, L. A., Clothier, K. A., Griffith, R. W., Baynes, R. E., and Riviere, J. E. (2011) Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats, J Vet Pharmacol Ther.

18. Kline, Y., Clemons, K. V., Woods, L., Stevens, D. A., and Tell, L. A. (2011) Pharmacokinetics of voriconazole in adult mallard ducks (Anas platyrhynchos), Medical mycology 49, 500-512.

19. Hawkins, M. G., Taylor, I. T., Byrne, B. A., Armstrong, R. D., and Tell, L. A. (2011) Pharmacokinetic-pharmacodynamic integration of orbifloxacin in Japanese quail (Coturnix japonica) following oral and intravenous administration, J Vet Pharmacol Ther 34, 350-358.

20. Goetting, V., Lee, K. A., and Tell, L. A. (2011) Pharmacokinetics of veterinary drugs in laying hens and residues in eggs: a review of the literature, J Vet Pharmacol Ther 34, 521-556.

21. Dore, E., Angelos, J. A., Rowe, J. D., Carlson, J. L., Wetzlich, S. E., Kieu, H. T., and Tell, L. A. (2011) Pharmacokinetics of ceftiofur crystalline free acid after single subcutaneous administration in lactating and nonlactating domestic goats (Capra aegagrus hircus), J Vet Pharmacol Ther 34, 25-30.

22. Cornwell, E. R., Eckerlin, G. E., Getchell, R. G., Groocock, G. H., Thompson, T. M., Batts, W. N., Casey, R. N., Kurath, G., Winton, J. R., Bowser, P. R., Bain, M. B., and Casey, J. W. (2011) Detection of viral hemorrhagic septicemia virus by quantitative reverse transcription polymerase chain reaction from two fish species at two sites in Lake Superior, J Aquat Anim Health 23, 207-217.

23. Cornwell, E. R., Cinelli, M. J., McIntosh, D. M., Blank, G. S., Wooster, G. A., Groocock, G. H., Getchell, R. G., and Bowser, P. R. (2011) Epizootic Nocardia infection in cultured weakfish, Cynoscion regalis (Bloch and Schneider), J Fish Dis 34, 567-571.

24. Clothier, K. A., Leavens, T., Griffith, R. W., Wetzlich, S. E., Baynes, R. E., Riviere, J. E., and Tell, L. A. (2011) Pharmacokinetics of tulathromycin after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus), J Vet Pharmacol Ther 34, 448-454.

25. Clothier, K. A., Leavens, T., Griffith, R. W., Wetzlich, S. E., Baynes, R. E., Riviere, J. E., and Tell, L. A. (2011) Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus), J Vet Pharmacol Ther.

26. Young, G., Smith, G. W., Leavens, T. L., Wetzlich, S. E., Baynes, R. E., Mason, S. E., Riviere, J. E., and Tell, L. A. (2010) Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats, Res Vet Sci.

27. Tell, L. A., Clemons, K. V., Kline, Y., Woods, L., Kass, P. H., Martinez, M., and Stevens, D. A. (2010) Efficacy of voriconazole in Japanese quail (Coturnix japonica) experimentally infected with Aspergillus fumigatus, Medical mycology 48, 234-244.

28. Rowe, J. D., Tell, L. A., Carlson, J. L., Griffith, R. W., Lee, K., Kieu, H., Wetzlich, S., and Hallford, D. (2010) Progesterone milk residues in goats treated with CIDR-G((R)) inserts, J Vet Pharmacol Ther 33, 605-609.

29. Hope, K. M., Casey, R. N., Groocock, G. H., Getchell, R. G., Bowser, P. R., and Casey, J. W. (2010) Comparison of quantitative RT-PCR with cell culture to detect viral hemorrhagic septicemia virus (VHSV) IVb infections in the Great Lakes, J Aquat Anim Health 22, 50-61.

30. Clothier, K. A., Jordan, D. M., Loynachan, A. T., and Griffith, R. W. (2010) Safety evaluation of tulathromycin use in the caprine species: tulathromycin toxicity assessment in goats, J Vet Pharmacol Ther 33, 499-502.

31. Bain, M. B., Cornwell, E. R., Hope, K. M., Eckerlin, G. E., Casey, R. N., Groocock, G. H., Getchell, R. G., Bowser, P. R., Winton, J. R., Batts, W. N., Cangelosi, A., and Casey, J. W. (2010) Distribution of an invasive aquatic pathogen (viral hemorrhagic septicemia virus) in the Great Lakes and its relationship to shipping, PLoS One 5, e10156.

32. Spitsbergen, J. M., Blazer, V. S., Bowser, P. R., Cheng, K. C., Cooper, K. R., Cooper, T. K., Frasca, S., Jr., Groman, D. B., Harper, C. M., Law, J. M., Marty, G. D., Smolowitz, R. M., St Leger, J., Wolf, D. C., and Wolf, J. C. (2009) Finfish and aquatic invertebrate pathology resources for now and the future, Comp Biochem Physiol C Toxicol Pharmacol 149, 249-257.

33. Rowe, J. D., Tell, L. A., and Wagner, D. C. (2009) Animal safety report on intravaginal progesterone controlled internal drug releasing devices in sheep and goats, J Vet Pharmacol Ther 32, 303-305.

34. Nguyen, K. Q., Hawkins, M. G., Taylor, I. T., Wiebe, V. J., and Tell, L. A. (2009) Stability and uniformity of extemporaneous preparations of voriconazole in two liquid suspension vehicles at two storage temperatures, Am J Vet Res 70, 908-914.

35. Kosoff, R. E., Chen, C. Y., Wooster, G. A., Getchell, R. G., Bowser, P. R., Clifford, A., Craig, J. L., Lim, P., Wetzlich, S. E., Craigmill, A. L., and Tell, L. A. (2009) Florfenicol residues in three species of fish after 10-day oral dosing in feed, J Aquat Anim Health 21, 8-13.

36. Davis, J. L., Smith, G. W., Baynes, R. E., Tell, L. A., Webb, A. I., and Riviere, J. E. (2009) Update on drugs prohibited from extralabel use in food animals, J Am Vet Med Assoc 235, 528-534.

37. Bowser, P. R., Kosoff, R. E., Chen, C. Y., Wooster, G. A., Getchell, R. G., Craig, J. L., Lim, P., Wetzlich, S. E., Craigmill, A. L., and Tell, L. A. (2009) Florfenicol residues in Nile tilapia after 10-d oral dosing in feed: effect of fish size, J Aquat Anim Health 21, 14-17.

38. Smith, G. W., Davis, J. L., Tell, L. A., Webb, A. I., and Riviere, J. E. (2008) Extralabel use of nonsteroidal anti-inflammatory drugs in cattle, J Am Vet Med Assoc 232, 697-701.

03/12/2014

1. Wu, H., Baynes, R. E., Leavens, T., Tell, L. A., and Riviere, J. E. (2013) Use of population pharmacokinetic modeling and Monte Carlo simulation to capture individual animal variability in the prediction of flunixin withdrawal times in cattle, J Vet Pharmacol Ther 36, 248-257.

2. Washburn, K. E., Fajt, V. R., Lawhon, S. D., Adams, L. G., Tell, L. A., and Bissett, W. T. (2013) Caprine abscess model of tulathromycin concentrations in interstitial fluid from tissue chambers inoculated with Corynebacterium pseudotuberculosis following subcutaneous or intrachamber administration, Antimicrobial agents and chemotherapy 57, 6295-6304.

3. Spitsbergen, J. M., Frattini, S. A., Bowser, P. R., Getchell, R. G., Coffee, L. L., Wolfe, M. J., Fisher, J. P., Marinovic, S. J., and Harr, K. E. (2013) Epizootic neoplasia of the lateral line system of lake trout (Salvelinus namaycush) in New York's Finger Lakes, Vet Pathol 50, 418-433.

4. Snook, T. S., White, S. D., Hawkins, M. G., Tell, L. A., Wilson, L. S., Outerbridge, C. A., and Ihrke, P. J. (2013) Skin diseases in pet rabbits: a retrospective study of 334 cases seen at the University of California at Davis, USA (1984-2004), Veterinary dermatology.

5. Shelver, W. L., Tell, L. A., Wagner, S., Wetzlich, S. E., Baynes, R. E., Riviere, J. E., and Smith, D. J. (2013) Comparison of ELISA and LC-MS/MS for the Measurement of Flunixin Plasma Concentrations in Beef Cattle after Intravenous and Subcutaneous Administration, J Agric Food Chem 61, 2679-2686.

6. McDonnel, S. J., Tell, L. A., and Murphy, B. G. (2013) Pharmacokinetics and pharmacodynamics of suberoylanilide hydroxamic acid in cats, J Vet Pharmacol Ther.

7. Macpherson, M. L., Giguere, S., Hatzel, J. N., Pozor, M., Benson, S., Diaw, M., Sanchez, L. C., Vickroy, T. W., Tell, L., Wetzlich, S., and Sims, J. (2013) Disposition of desfuroylceftiofur acetamide in serum, placental tissue, fetal fluids, and fetal tissues after administration of ceftiofur crystalline free acid (CCFA) to pony mares with placentitis, J Vet Pharmacol Ther 36, 59-67.

8. Grismer, B., Rowe, J. D., Carlson, J., Wetzlich, S. E., and Tell, L. A. (2013) Pharmacokinetics of tulathromycin in plasma and milk samples after a single subcutaneous injection in lactating goats (Capra hircus), J Vet Pharmacol Ther.

9. Goetting, V., Lee, K. A., Woods, L., Clemons, K. V., Stevens, D. A., and Tell, L. A. (2013) Inflammatory marker profiles in an avian experimental model of aspergillosis, Medical mycology 51, 696-703.

10. DeDonder, K. D., Gehring, R., Baynes, R. E., Tell, L. A., Vickroy, T. W., Apley, M. D., and Riviere, J. E. (2013) Effects of new sampling protocols on procaine penicillin G withdrawal intervals for cattle, J Am Vet Med Assoc 243, 1408-1412.

11. Dechant, J. E., Rowe, J. D., Byrne, B. A., Wetzlich, S. E., Kieu, H. T., and Tell, L. A. (2013) Pharmacokinetics of ceftiofur crystalline free acid after single and multiple subcutaneous administrations in healthy alpacas (Vicugna pacos), J Vet Pharmacol Ther 36, 122-129.

12. Cornwell, E. R., Labuda, S. L., Groocock, G. H., Getchell, R. G., and Bowser, P. R. (2013) Experimental Infection of Koi Carp with viral hemorrhagic septicemia virus type IVb, J Aquat Anim Health 25, 36-41.

13. Cornwell, E. R., Bellmund, C. A., Groocock, G. H., Wong, P. T., Hambury, K. L., Getchell, R. G., and Bowser, P. R. (2013) Fin and gill biopsies are effective nonlethal samples for detection of viral hemorrhagic septicemia virus genotype IVb, J Vet Diagn Invest 25, 203-209.

14. Coffee, L. L., Casey, J. W., and Bowser, P. R. (2013) Pathology of tumors in fish associated with retroviruses: a review, Vet Pathol 50, 390-403.

15. Coffee, L. L., Bogdanovic, L. B., Cushing, T. L., and Bowser, P. R. (2013) Pharyngeal odontoma in an adult walleye (Sander vitreus), Vet Pathol 50, 483-487.

08/01/2014

Publications During this Period

1) Rivera-Garcia, S., Angelos, J. A., Rowe, J. D., Byrne, B. A., Wetzlich, S. E., Van Liew, D. B., and Tell, L. A. (2014) Pharmacokinetics of ceftiofur crystalline-free acid following subcutaneous administration of a single dose to sheep, Am J Vet Res 75, 290-295.

2) McDonnel, S. J., Tell, L. A., and Murphy, B. G. (2014) Pharmacokinetics and pharmacodynamics of suberoylanilide hydroxamic acid in cats, J Vet Pharmacol Ther 37, 196-200.

3) Kinney, M. E., Lamberski, N., Wack, R., Foster, R., Neely, M., Tell, L., and Gehring, R. (2014) Population pharmacokinetics of a single intramuscular administration of tulathromycin in adult desert tortoises (Gopherus agassizii), J Vet Pharmacol Ther 37, 500-507.

4) Grismer, B., Rowe, J. D., Carlson, J., Wetzlich, S. E., and Tell, L. A. (2014) Pharmacokinetics of tulathromycin in plasma and milk samples after a single subcutaneous injection in lactating goats (Capra hircus), J Vet Pharmacol Ther 37, 205-208.

5) Griffith, R., Yaeger, M., Hostetter, S., Tell, L. A., Wetzlich, S., Vickroy, T., Lillie, B., MacFarlane, W., Laudenslager, T., Whitley, E., Dzikamunhenga, R., and Larson, W. (2014) Safety of fenbendazole in Chinese ring-necked pheasants (Phasianus colchicus), Avian Dis 58, 8-15.

6) Groocock, G.H., Getchell, R.G., Cornwell, E.R. Frattini, S.A. Wooster, G.A. and Bowser, P.R. (2013) Iodophor disinfection of walleye eggs exposed to viral hemorrhagic septicemia virus type iVB. North American Journal of Aquaculture. 75:25-33.

7) Wu, H., Baynes, R. E., Leavens, T., Tell, L. A., and Riviere, J. E. (2013) Use of population pharmacokinetic modeling and Monte Carlo simulation to capture individual animal variability in the prediction of flunixin withdrawal times in cattle, J Vet Pharmacol Ther 36, 248-257.

8) Washburn, K. E., Fajt, V. R., Lawhon, S. D., Adams, L. G., Tell, L. A., and Bissett, W. T. (2013) Caprine abscess model of tulathromycin concentrations in interstitial fluid from tissue chambers inoculated with Corynebacterium pseudotuberculosis following subcutaneous or intrachamber administration, Antimicrobial Agents and Chemotherapy 57, 6295-6304.

Abstracts and Presentations

1. Smith J, Angelos J, Rowe J, Carlson J, Lee, L, Tell LA. Pharmacokinetics of flunixin meglumine in plasma and milk of domestic goats (Capra aegagrus hircus) following single subcutaneous dosing. UC Davis Goat Day, Davis, CA, February 1, 2014, UC Davis 36th Annual House Officer Seminar Day, Davis, CA, March 21st, 2014 and ACVIM Annual Meeting, Nashville, TN, June 4-7, 2014.

2. Breyer, K.E. 2013. Evaluating the efficacy of a low-dose Garlic Compound (Allicin) Against Infection With Aeromonas salmonicida In Rainbow Trout. Master Of Science Thesis, Cornell University. 45 Pp.

3. Breyer, K.E. , Getchell, R., Wooster, G., Ketola, G., and Bowser, P. (2013) Evaluating the efficacy of a low-dose garlic compound against Aeromonas salmonicida in Rainbow trout. 2013 Clinical Investigator’s Day, Cornell University, Ithaca, New York. 18 March 2013. (Keb: Honorable Mention Award).

4. Breyer, K.E. , Getchell, R., Wooster, G., Ketola, G., and Bowser, P. (2013) Update! Garlic (Allicin): More than just flavor for your fish. 38th Eastern Fish Health Workshop, Gettysburg, PA. 29 April – 3 May 2013.

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